Diseases Commons^™

Small B Cell Non-Hodgkins Lymphoma In Pakistan, Kanwal Aftab, Yasmin Bhurgri, Shahid Pervez

Department of Pathology and Laboratory Medicine

Objective: To study the pattern of small B cell lymphomas in Pakistan.

Methods: This descriptive study was carried out at the Aga Khan University Hospital pathology department including 1721 cases of Non-Hodgkins Lymphoma (NHL) diagnosed during a period of five years (1998-2002) and classified according to REAL/WHO classification. The antibodies used included Leukocyte Common Antigen (LCA), Pan B (CD20, CD79a), Pan T (UCHL-1), Bcl 2, Mib 1(Ki 67) and Cyclin D1 (Dako, Denmark).

Results: Out of the 1721 NHL cases, only 140 (8.1%) could be categorized as small B-cell NHL. The study group comprised small lymphocytic lymphoma/chronic lymphocytic leukemia (58 …

Eliciting Facial Expressions In Children With And Without Down Syndrome, Orietta Coz

Master's Theses

This study investigated facial expressions of children between the ages of 10 and 15 years with Down Syndrome (experimental group) and compared them to typically developing children (control group). Elicitation of facial expressions was carried out through showings of video clips. Trained observers were used to code expressions of happiness, anger, and disgust from video recordings that were made of the children’s reactions while they watched the video clips.

I hypothesized that Down Syndrome children will not differ from typically developing children in the frequency of elicited happy expressions. However, I expected them to differ in the frequency of elicited …

Premature Induction Of An Immunosuppressive Regulatory T Cell Response During Acute Simian Immunodeficiency Virus Infection, Jacob D. Estes, Qingsheng Li, Matthew R. Reynolds, Stephen W. Wietgrefe, Lijie Duan, Timothy Schacker, Louis J. Picker, David I. Watkins, Jeffrey D. Lifson, Cavan Reilly, John V. Carlis, Ashley T. Haase

Qingsheng Li Publications

Here we report the results of an investigation into the possibility that one mechanism responsible for the establishment of persistent human immunodeficiency virus infection is an early regulatory T (T_reg) cell response that blunts virus- specific responses. Using the simian immunodeficiency virus (SIV)–infected rhesus macaque model, we show that, indeed, viral replication and immune activation in lymphatic tissue drive a premature immunosuppressive response, with dramatic increases in the frequencies of CD4⁺CD25⁺FOXP3⁺ Treg cells, transforming growth factor–β1⁺ cells, interleukin–10+ cells, and indoleamine 2,3-dioxygenase+CD3⁺ cells.When we compared SIV infection with rhesus cytomegalovirus (RhCMV) …

Infectious Diseases Of The Eye: Loa Loa, Onchocerciasis, & Trachoma, Lindsay N. Wise

Honors Program Theses

On December 16, 2006, I will graduate from the University of Northem Iowa with University Honors and a B.A. in both biology and psychology. I have always been interested in medicine and diseases, and this semester I wanted to explore some options for my future. At the start of the semester, I was considering applying to optometry schools after graduating from UNI. I am also highly interested in going on a mission trip, and perhaps a medical mission trip. ln light of these interests, I decided to design my senior honors thesis around infectious diseases of the eye. With the …

Religious And Denominational Problems In Nevada, Noel Tiano

Social Health of Nevada Reports

Ever since the earliest civilizations, humans have sought to make sense of their relationship with other beings, the universe, and the unknown through religious beliefs and practices. Shamans and healers interpreted phenomena for their followers, nuns cared for the sick and dying, ministers spearheaded anti-slavery movements, and religious activists joined campaigns for prison reform, worked for charitable organizations, and promoted novel educational institutions. Mother Theresa, Gandhi, Martin Luther King, Jr., the Dalai Lama and other world leaders with strong religious convictions have shown us what love in action means

Inside Unlv, Shane Bevell

Inside UNLV

No abstract provided.

Suicide Trends And Prevention In Nevada, Matt Wray

Social Health of Nevada Reports

Suicide has been around for as long as human society and it continues to challenge our collective wisdom. Consider this data provided by the National Institute of Medicine:

• Each year about one million people commit suicide worldwide.
• Every year some 30,000 Americans end their lives by suicide, and approximately 650,000 people receive emergency treatment after attempting suicide.
• Every 41 seconds someone in the U.S. attempts suicide; every 16.7 minutes, someone completes suicide; and every day over 85 people die by suicide.
• Suicide is the eighth leading cause of death in the U.S. and the third leading cause of death among …

Problem Gambling And Treatment In Nevada, Bo Bernhard

Social Health of Nevada Reports

For many years, it was moral experts, rather than medical and academic ones, who told us who gambled “too much.” Speaking from pulpits rather than podiums, church leaders informed us that gambling was uniquely subversive of the American way of life, for its something-for-nothing promise threatened to undermine the popular ethic of honest toil and gradual accumulation of goods. Samuel Hopkins, in an 1835 sermon on “The Evils of Gambling,” captured this sensibility: “Let the gambler know that he is watched, and marked; and that . . . he is loathed. Let the man who dares to furnish a resort …

Teen Sexuality And Pregnancy In Nevada, Marta Meana, Lea Thaler

Social Health of Nevada Reports

The United States has the highest rate of teen pregnancy in the fully industrialized world. While the rates have been declining in the last 15 years, it remains a source of concern that

• 34% of teenage girls in the U.S. are becoming pregnant at least once before the age of 20.
• The teen pregnancy in the U.S. rate is ten times that of Japan, four times those of France and Germany, and nearly twice that of Great Britain.

Diseases Prevalence And Behavioral Choices In Nevada, Mary Guinan, Chad L. Cross, Lawrence Sands

Social Health of Nevada Reports

Determining the health of a state population is a complex task. It involves knowing at least the prevalence of various diseases and conditions as well as the leading causes of death and disability compared to a national mean or median. The World Health Organization defines health as “a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.” Since health is affected by numerous social, economic, environmental, and cultural factors, these factors must also be considered when examining the health status of a population. All attempts to rank states in health are limited …

Health Care Access And Insurance Availability In Nevada, Charles B. Moseley, Michelle Sotero

Social Health of Nevada Reports

According to the Institute of Medicine (IOM),

• Approximately 18,000 Americans die prematurely every year, solely because they lack health insurance coverage (Institute of Medicine, 2004).
• The IOM estimates that the aggregate cost of increased morbidity and mortality due to un-insurance in the U.S. is between $65 billion and $130 billion per year.
• Costs to the health care system can be measured conservatively in terms of the value of uncompensated care provided to the uninsured, estimated at almost $35 billion in 2001, of which $24 billion was provided by hospitals.

Access to medical care is not a constitutional right in the …

Molecular Characterization Of A Tsetse Fly Midgut Proteolytic Lectin That Mediates Differentiation Of African Trypanosomes, Laila U. Abubakar, Wallace D. Bulimo, Francis J. Mulaa, Ellie O. Osir

All Peer-Reviewed Publications

Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. …