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Articles 121 - 123 of 123

Full-Text Articles in Diseases

Alzheimer's Disease Cerebrospinal Fluid Biomarkers Are Not Influenced By Gravity Drip Or Aspiration Extraction Methodology, Alan Rembach, Lisbeth A. Evered, Qiao-Xin Li, Tabitha Nash, Lesley Vidaurre, Christopher J. Fowler, Kelly K. Pertile, Rebecca L. Rumble, Brett O. Trounson, Sarah Maher, Francis Mooney, Maree Farrow, Kevin Taddei, Stephanie Rainey-Smith, Simon Laws, S. Lance Macaulay, William Wilson, David G. Darby, Ralph N. Martins, David Ames, Steven Collins, Brendon Silbert, Colin L. Masters, James D. Doecke Jan 2015

Alzheimer's Disease Cerebrospinal Fluid Biomarkers Are Not Influenced By Gravity Drip Or Aspiration Extraction Methodology, Alan Rembach, Lisbeth A. Evered, Qiao-Xin Li, Tabitha Nash, Lesley Vidaurre, Christopher J. Fowler, Kelly K. Pertile, Rebecca L. Rumble, Brett O. Trounson, Sarah Maher, Francis Mooney, Maree Farrow, Kevin Taddei, Stephanie Rainey-Smith, Simon Laws, S. Lance Macaulay, William Wilson, David G. Darby, Ralph N. Martins, David Ames, Steven Collins, Brendon Silbert, Colin L. Masters, James D. Doecke

Research outputs 2014 to 2021

Introduction Cerebrospinal fluid (CSF) biomarkers, although of established utility in the diagnostic evaluation of Alzheimer’s disease (AD), are known to be sensitive to variation based on pre-analytical sample processing. We assessed whether gravity droplet collection versus syringe aspiration was another factor influencing CSF biomarker analyte concentrations and reproducibility. Methods Standardized lumbar puncture using small calibre atraumatic spinal needles and CSF collection using gravity fed collection followed by syringe aspirated extraction was performed in a sample of elderly individuals participating in a large long-term observational research trial. Analyte assay concentrations were compared. Results For the 44 total paired samples of gravity …


Long-Term Effect Of Respiratory Training For Chronic Obstructive Pulmonary Disease Patients At An Outpatient Clinic: A Randomised Controlled Trial, Feng Xi, Zheng Wang, Yong Qi, Richard F. Brightwell, Peter Roberts, Angus Stewart, Wei Wang Jan 2015

Long-Term Effect Of Respiratory Training For Chronic Obstructive Pulmonary Disease Patients At An Outpatient Clinic: A Randomised Controlled Trial, Feng Xi, Zheng Wang, Yong Qi, Richard F. Brightwell, Peter Roberts, Angus Stewart, Wei Wang

Research outputs 2014 to 2021

Objective: To assess the effect of respiratory training (RT ) on lung function, activity tolerance and acute exacerbation frequency with chronic obstructive pulmonary disease (COPD). Design: A randomised controlled trial. Setting: Outpatient clinic and home of the COPD patients, Zhengzhou City, China. Subjects: Sixty participants with COPD were randomised into two groups: an intervention group ( n = 30) which received the RT in self-management and a control group ( n = 30) that received an education program during the study. Intervention: Pulmonary function, activity tolerance and frequency of acute exacerbation of these COPD patients were evaluated before and after …


Risk Factors Of Cvd Mortality Among The Elderly In Beijing, 1992 - 2009: An 18-Year Cohort Study, Tao Zhou, Xia Li, Zhe Tang, Changchun Xie, Lixin Tao, Lei Pan, Da Huo, Fei Sun, Yanxia Luo, Wei Wang, Aoshuang Yan, Xiuhua Guo Jan 2014

Risk Factors Of Cvd Mortality Among The Elderly In Beijing, 1992 - 2009: An 18-Year Cohort Study, Tao Zhou, Xia Li, Zhe Tang, Changchun Xie, Lixin Tao, Lei Pan, Da Huo, Fei Sun, Yanxia Luo, Wei Wang, Aoshuang Yan, Xiuhua Guo

Research outputs 2014 to 2021

Few researchers have examined the effects of multiple risk factors of cardiovascular disease (CVD) mortality simultaneously. This study was to determine the associations of combined lifestyle and other factors with CVD mortality among the elderly (n = 3,257), in Beijing, China, through data mining of the Beijing Longitudinal Study of Aging (BLSA). BLSA is a representative cohort study from 1992 to 2009, hosted by Xuan Wu Hospital. Competing risk survival analysis was conducted to explore the association between risk factors and CVD mortality. The factors focused mainly on lifestyle, physical condition, and the model was adjusted for age and gender. …