Diseases Commons^™

Coronavirus Update 3-23-22, The Coronavirus Planning Team

University Briefings & Virtual Events

There will be a booster clinic on campus this coming Saturday, March 26, from 10 a.m. to 2 p.m. in the Edgerton Center atrium. The clinic will be open to SHU community members and their family and friends.

Covid-19 Newsletter (Vol. 111), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Epidemiology, Clinical Ramifications, And Cellular Pathogenesis Of Covid-19 Mrna-Vaccination-Induced Adverse Cardiovascular Outcomes: A State-Of-The-Heart Review, Talal Almas, Sarah Rehman, Eyad Mansour, Tarek Khedro, Ali Alansari, Jahanzeb Malik, Norah Alshareef, Vikneswaran Raj Nagarajan, Abdulla Hussain Al-Awaid, Reema Alsufyani

Medical College Documents

The coronavirus disease 2019 (COVID-19) has overwhelming healthcare systems globally. To date, a myriad of therapeutic regimens has been employed in an attempt to curb the ramifications of a severe COVID-19 infection. Amidst the ongoing pandemic, the advent and efficacious uptake of COVID-19 vaccination has significantly reduced disease-related hospitalizations and mortality. Nevertheless, many side-effects are being reported after COVID-19 vaccinations and myocarditis is the most commonly reported sequelae post vaccination. Majority of these diseases are associated with COVID-19 mRNA vaccines. Various studies have established a temporal relationship between these complications, yet the causality and the underlying pathogenesis remain hypothetical. In …

The Who Global Tuberculosis 2021 Report - Not So Good News And Turning The Tide Back To End Tb, Chakaya Jeremiah, Eskild Petersen, Rebecca Nantanda, Brenda N. Mungai, Giovanni Battista Migliori, Farhana Amanullah, Patrick Lungu, Francine Ntoumi, Nagalingeswaran Kumarasamy

Department of Paediatrics and Child Health

Objective: To review the data presented in the 2021 WHO global TB report and discuss the current constraints in the global response.
Introduction and methods: The WHO global TB reports, consolidate TB data from countries and provide up to date assessment of the global TB epidemic. We reviewed the data presented in the 2021 report.
Results: We noted that the 2021 WHO global TB report presents a rather grim picture on the trajectory of the global epidemic of TB including a stagnation in the annual decline in TB incidence, a decline in TB notifications and an increase in estimated TB …

The Response To Covid-19 Among Drug Retail Outlets In Indonesia: A Cross-Sectional Survey Of Knowledge, Attitudes, And Practices, Yusuf Ari Mashuri, Luh Putu Lila Wulandari, Mishal Khan, Astri Ferdiana, Ari Probandari, Tri Wibawa, Neha Batura, Marco Liverani, Richard Day, Stephen Jan

Community Health Sciences

Background: Pharmacists have been at the frontline of the COVID-19 response in Indonesia, providing medicines, advice, and referral services often in areas with limited healthcare access. This study aimed to explore their knowledge, attitudes, and practices during the pandemic, so that we can be better prepared for future emergencies.
Methods: A cross-sectional online survey of community pharmacists and pharmacy technicians in Indonesia was conducted between July and August 2020. The dataset was analysed descriptively, and logistic regression was used to explore willingness to participate in COVID-19 interventions.
Findings: 4716 respondents participated in the survey. Two-thirds (66·7%) reported knowing only "a …

Covid-19 Newsletter (Vol. 110), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

If Past Is Prologue, Then The Future Is Bleak: Contracts, Covid–19, And The Changed Circumstances Doctrines, Danielle K. Hart

Texas A&M Law Review

At the heart of most of the systemic problems currently confronting individuals and businesses as a result of the COVID–19 pandemic is quite literally a contract. Housing. Insurance. Food. Health care. Child care. Employment. Manufacturing. Construction. Supply chains. You name it. Contracts are implicated everywhere. So make no mistake: How contract law addresses these ostensibly private contracts will have profound social consequences. If the past really is prologue, then the future is indeed bleak. The empirical study conducted for this Article establishes what the conventional wisdom has claimed for the last 70 years. More specifically, the empirical study here shows …

Coronavirus Update 3-10-22, The Coronavirus Planning Team

University Briefings & Virtual Events

As you know, the deadline for employees to receive a booster shot was March 1, and the deadline for students is March 15. Anyone who has received an exemption or has not complied with the booster deadline will need to be tested weekly throughout the remainder of the semester. We also recommend that those who have not been vaccinated and/or received a booster wear a mask indoors.

The Covid-19 Pandemic: Exploring E-Learning Experience During Schools Closure In Tanzania, Fabian Gallus Mahundu

Journal of Humanities and Social Sciences

of parents and guardians in supporting their children’s e-learning activities during the COVID-19 lockdown in Tanzania. The study adopted an exploratory qualitative research design. Data were collected using telephone interviews and open-ended questions (using google forms), which inquired parents’ and guardians’ experience in supporting home based e-learning activities among students during the COVID-19 lockdown. The paper argues that giving students free access to online learning materials during COVID-19 lockdowns is paramount. However, parents’ and guardians’ support through sharing one’s phones must be monitored to safeguard learners from accessing irrelevant materials. Findings show that parents and guardians had different experiences in …

Antibacterial And Anti-Hiv-1 Gp120 Activities Of Selected Medicinal Plants, Rose J. Masalu, Cyprian B. Mpinda

Journal of Humanities and Social Sciences

Medicinal plants play an important role in traditional medicine and drug development research because of their numerous bioactivities. However, some concerns have risen on the inefficiencies of such products due to improper use of medicinal plant products, notably when mixed with other traditional remedies. This study evaluates the antibacterial and anti-human immunodeficiency virus 1 glycoprotein 120/CD4 (anti-HIV-1 GP120/CD4) activities of medicinal plants species Sapium ellipticum, Pseudospondias microcarpa, and Capparis erythrocarpos; and their respective combinations effects. Results revealed that aqueous and ethyl acetate extracts of S. ellipticum and P. microcarpa had antimicrobial activities against S. aureus (ATCC 25923), E. coli (ATCC …

Spatial Deconcentration Of Tourism Concentrations: A Visitors’ Galaxy Impact Model Of The Covid-19 Crisis, Jaewon Lim, Karima Kourtit, Peter Nijkamp, Christopher Stream

Public Policy and Leadership Faculty Research

This paper analyzes the impact of COVID-19 on mass tourism concentrations, such as Las Vegas. It argues that health risks and perceptions may induce a more deconcentrated pattern of mass tourism, with more geographical dispersion to rural and natural areas. The analytical framework is modeled and applied to extensive data on Las Vegas tourism. The proposition on deconcentrated tourism concentrations is confirmed. Pre-pandemic outer-inner city complementary relations between “Outdoor Activities” in 11 surrounding national parks and the “Gaming Industry” in Las Vegas have transformed into outer-inner city substitution relations in the COVID-19 pandemic. This represents the evolving deconcentration of tourism …

Covid-19 Newsletter (Vol. 109), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Coronavirus Update 3-3-22, The Coronavirus Planning Team

University Briefings & Virtual Events

We have scheduled a booster clinic on campus on Saturday.

We want to remind you to make sure you have picked up your at-home COVID test before you leave for break. Please take the test the morning that you first plan to return to campus.

Association Between Diagnosed Anxiety And Depression And Exposure To Life Stressors During The Covid-19 Pandemic, Emily Hallgren Phd, Don E. Willis Phd, Brett Rowland Ma, James P. Selig Phd, Pearl A. Mcelfish Phd

Journal of Health Disparities Research and Practice

Research suggests that mental health disorders heighten the risk of exposure to life stressors. Drawing on a sample of 754 adults from a survey distributed at six primary care clinics, we examine whether adults who reported ever being diagnosed with depression or anxiety were more likely to experience an employment disruption, a housing disruption, and/or report more COVID-19-related stressors during the COVID-19 pandemic. Individuals who reported ever being diagnosed with depression reported a greater burden (B=.75) of COVID-19-related stressors. Those who reported ever being diagnosed with anxiety had higher odds of experiencing an employment disruption (OR=1.90) and a housing disruption …

Perceptions Of Physical Therapy Clinicians Regarding The Impact Of Covid 19 On Patients’ Mental Health, Brandy Chase, Amy L. Barnett

Faculty Articles & Research

• Research shows that the COVID 19 outbreak can negatively affect a person’s mental health, especially those at a higher risk with debilitating conditions (Javed, Sarwer, & Soto, 2020).
• This alludes to the need to take a closer look at the impact of COVID 19 on physical therapy patients and the amount of mental health training needed by physical therapy clinicians.

Covid-19 Newsletter (Vol. 108), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Use Of Steroids In Covid-19 Patients: What Is Known?, Syed Muhammad Mustahsan, Marzia Tahir, Emaduddin Siddiqui

Department of Emergency Medicine

COVID-19 pandemic has exaggerated the role of steroids in the standard of care despite minimum direct evidence of their efficacy in COVID-19 patients and their well-known adverse effects. The literature abounds on the side effects of steroids affecting different organ systems of the body. COVID-19 patients, who are on long-term steroids, are more susceptible to their adverse effects. We, herein, briefly review the potential uses and the adverse effects of steroids on different organ systems of the body. Key Words: Steroids, COVID-19, Adverse effects.

Coronavirus Update 2-24-22, The Coronavirus Planning Team

University Briefings & Virtual Events

Given the low numbers of positive cases on campus and the trends at other campuses and in towns and cities in the area, we are modifying our indoor mask mandate, effective March 1.

Covid-19 Newsletter (Vol. 107), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Pulmonary Post-Acute Sequelae Of Covid-19, Usman Akbar, Shivam Gulati, Johnny Zakhour Md, Alex Glynn, Jose Bordon

The University of Louisville Journal of Respiratory Infections

Introduction: Persistent symptoms have been observed in a substantial proportion of survivors of COVID-19 since relatively early in the pandemic. Among these post-acute sequelae of COVID-19 (PASC), respiratory symptoms appear to be the most prevalent.

Methods: We conducted a literature review of peer-reviewed publications in English on the clinical and epidemiological features of respiratory PASC in cohorts of 100 or more patients with a follow-up of four weeks or more after acute infection. Included studies reported the prevalence of persistent respiratory symptoms and/or the results of follow-up pulmonary function tests.

Results: On our review included 14 studies across eight countries …

Compliance With Guidelines For Treatment Of Staphylococcus Aureus Bacteremia Is Associated With Decreased Mortality In Patients Hospitalized For Community-Acquired Pneumonia With Staphylococcus Aureus Bacteremia, Leslie Beavin, Vidyulata Salunkhe, Shashvin Singh, Ahmed Gana, Balaji Sekaran, Mahder A. Tella, Stephen P. Furmanek, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

Introduction: Staphylococcus aureus bacteremia has a minimum treatment duration of two weeks, while S. aureus community-acquired pneumonia (CAP) treatment is at least five days. Treatment failure, persistent bacteremia, and recurrence are common among patients with community-acquired S. aureus bacteremia. There is conflicting information in the current Infectious Diseases Society of America (IDSA) guidelines for the treatment of S.aureus bacteremia patients with CAP. Therefore, the appropriate treatment duration and modality for S. aureus CAP with bacteremia is unclear. The objective of this study was to compare outcomes among patients with S. aureus CAP and bacteremia treated in compliance versus non-compliance with …

Allosteric Determinants Of The Sars-Cov-2 Spike Protein Binding With Nanobodies: Examining Mechanisms Of Mutational Escape And Sensitivity Of The Omicron Variant, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Structural and biochemical studies have recently revealed a range of rationally engineered nanobodies with efficient neutralizing capacity against the SARS-CoV-2 virus and resilience against mutational escape. In this study, we performed a comprehensive computational analysis of the SARS-CoV-2 spike trimer complexes with single nanobodies Nb6, VHH E, and complex with VHH E/VHH V nanobody combination. We combined coarse-grained and all-atom molecular simulations and collective dynamics analysis with binding free energy scanning, perturbation-response scanning, and network centrality analysis to examine mechanisms of nanobody-induced allosteric modulation and cooperativity in the SARS-CoV-2 spike trimer complexes with these nanobodies. By quantifying energetic and allosteric …

Covid-19 Newsletter (Vol. 106), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

“Hiccups” With Covid-19 Management, Yong W. Lee, Jacob Psomiadis, Sarah Akbani, Marvin Lopez-Medal, Aisha Miller

Advances in Clinical Medical Research and Healthcare Delivery

Hiccups, medically referred as singultus, is a condition that results from involuntary contraction of the diaphragm and intercostal muscles. Singultus is usually a self-limiting condition which typically lasts less than 48 hours but in rare cases, can persist greater than 48 hours. This is a case of a 48 year-old male who was prescribed dexamethasone for COVID-19 but developed intractable singultus for two weeks. Patient was unable to tolerate diet due to intractable singultus leading to vomiting. He underwent various non-pharmacological maneuvers and pharmacotherapy without resolution. Dexamethasone- induced hiccups have been reported as an under recognized side effect of dexamethasone. …

The Day The World Shut Down, Anonymous

Community Reflections

If I could tell only one thing to future generations about the hardships of the pandemic, I would tell them that no one thing in life is permanent. Things you could never imagine being temporary can be taken from you in an instant. The pandemic has taught me how to adapt during difficult times.

It Was Friday March 13th, Anonymous

Community Reflections

The Coronavirus is very similar to both “The Plague” and “The Black Death” in numerous ways. The spread of infection, self-quarantine, travel bans, and lack of a cure, are all qualities that these diseases share.

Challenging And Eye-Opening, Anonymous

Community Reflections

Standing next to us at the store was a man wearing a mask and gloves. Little did I know that that would be my attire for the next year.

Covid Pushed Me To Want To Be A Nurse Even More, Anonymous

Community Reflections

The biggest adjustment for other High school students as well as myself was switching from in-person to remote learning.

A Time Of Growth And Learning, Anonymous

Community Reflections

I spent most of my time reflecting, and I learned to appreciate what I already had and set new goals for myself.

Coronavirus Update 2-10-22, The Coronavirus Planning Team

University Briefings & Virtual Events

The Connecticut Governor’s state-wide mask mandate for K-12 schools is set to expire at the end of this month, leaving the decision up to local communities. Because the CDC still lists Fairfield County as a high-transmission area and, on the advice of state and local health officials, Sacred Heart will continue to require indoor masking for the time being.