Diseases Commons^™

Coronavirus Update 8-10-21, The Coronavirus Planning Team

University Briefings & Virtual Events

We are sharing this year’s version of the Pioneer Promise. While it remains a commitment to one another to follow protocols that will keep the community safe, it has been adapted to reflect fewer restrictions and procedures as we move toward more normalcy on campus. Just like last year, students, faculty and staff will be asked to sign the Pioneer Promise before the semester begins.

Coronavirus Update 8-6-21, The Coronavirus Planning Team

University Briefings & Virtual Events

As you know, the rise of the delta variant has put a little bit of a damper on things by necessitating, for now, that everyone wears masks indoors whether vaccinated or not. We know you are disappointed—we all are. But it is a small price to pay for the health and safety of our community. Here are some things we know about COVID-19 and the delta variant.

*Correction* Coronavirus Update 8-6-21, The Coronavirus Planning Team

University Briefings & Virtual Events

CORRECTION: The following statement from this morning’s coronavirus message was incorrect. Upperclassmen will move in on Sunday, August 29, not August 28. We apologize for any inconvenience.

Gender, Age And Staff Preparedness To Adopt Internet Tools For Research Sharing During Covid-19 In African Varsities, Valentine Joseph Owan, Michael Ekpenyong Asuquo Phd., Samuel Okpon Ekaette Ph.D., Sana Aslam, Moses Eteng Obla, Daniel Clement Agurokpon, Mercy Valentine Owan

Library Philosophy and Practice (e-journal)

This study assessed the partial as well as the collaborative impact of age and gender on academic staff preparedness to adopt Internet tools for research sharing in African universities during Covid-19. Although evidence abounds in the literature on gender and age as they affect relatively, scholars’ utilisation of digital tools for research communication, such studies did not examine scholars’ preparedness to adopt from a broad perspective of Africa. This study was conducted based on the argument that the preparedness of scholars may affect their future interest to utilize digital tools for research sharing. A quantitative method, based on the descriptive …

Covid-19 Newsletter (Vol. 83), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Perceptions And Experiences Of Healthcare Providers During Covid-19 Pandemic In Karachi, Pakistan: An Exploratory Qualitative Study, Anam Shahil Feroz, Nousheen Pradhan, Zarak Hussain Ahmed, Mashal Murad Shah, Nargis Asad, Sarah Saleem, Sameen Siddiqi

Community Health Sciences

Objective: To explore healthcare provider's perspectives and experiences of the barriers and facilitators to treat and manage COVID-19 cases.
Design and setting: We conducted an exploratory qualitative study using a purposive sampling approach, at a private tertiary care teaching hospital in Karachi, Pakistan. Study data were analysed manually using the conventional content analysis technique.
Participants: Key-informant interviews (KIIs) were conducted with senior management and hospital leadership and in-depth interviews (IDIs) were conducted with front-line healthcare providers.
Results: A total of 31 interviews (KIIs=19; IDIs=12) were conducted, between April and May 2020. Three overarching themes emerged. The first was 'challenges faced …

Host Cell Responses To Zika Virus Infection, Bikash Ranjan Sahoo

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

The re-emergence of Zika virus (ZIKV) in 2015 as a significant human pathogen causing neurological diseases in infants as well as adults is a serious global health concern. A clear understanding of the mechanisms involved in ZIKV replication in infected host cells as well as the host responses to virus infection are keys to the development of therapeutic strategies against ZIKV. Studies conducted in this dissertation demonstrate that ZIKV infection induces the activation of mTOR signaling cascade that promotes viral protein accumulation and infectious progeny production. While both mTORC1 and mTORC2 are essential for ZIKV replication, the observation that depletion …

Euadb: A Resource For Covid-19 Test Development And Comparison, Alyssa Woronik, Henry W. Shaffer, Karin Kiontke, Jon M. Laurent, Ronald Zambrano, Mariah Daley, Jef D. Boeke, David H. Fitch

Biology Faculty Publications

Due to the sheer number of COVID-19 (coronavirus disease 2019) cases there is a need for increased world-wide SARS-CoV-2 testing capability that is both efficient and effective. Having open and easy access to detailed information about these tests, their sensitivity, the types of samples they use, etc. would be highly useful to ensure their reproducibility, to help clients compare and decide which tests would be best suited for their applications, and to avoid costs of reinventing similar or identical tests. Additionally, this resource would provide a means of comparing the many innovative diagnostic tools that are currently being developed in …

Suppression Of Dc-Sign And Gh Reveals Complex, Subset-Specific Mechanisms For Kshv Entry In Primary B Lymphocytes, Nancy Palmerin, Farizeh Aalam, Romina Nabiee, Murali Muniraju, Javier Gordon Ogembo, Jennifer Totonchy

Pharmacy Faculty Articles and Research

Kaposi sarcoma-associated herpesvirus (KSHV) is the causative agent of multiple cancers in immunocompromised patients including two lymphoproliferative disorders associated with KSHV infection of B lymphocytes. Despite many years of research into the pathogenesis of KSHV associated diseases, basic questions related to KSHV molecular virology remain unresolved. One such unresolved question is the cellular receptors and viral glycoproteins needed for KSHV entry into primary B lymphocytes. In this study, we assess the contributions of KSHV glycoprotein H (gH) and the cellular receptor DC-SIGN to KSHV infection in tonsil-derived B lymphocytes. Our results show that (1) neither KSHV-gH nor DC-SIGN are essential …

Coronavirus Update 7-30-21, The Coronavirus Planning Team

University Briefings & Virtual Events

Message Highlights

1. Students, faculty and staff will need to have at least one dose of the vaccine before coming back to campus. Students must upload their proof of vaccination (even if it is only a first dose) to their SPA health portal.
2. Everyone needs to have their second injection by September 15 and will need to upload the information by that date.
3. Students may apply for a religious or medical exemption.
4. Unvaccinated students with an approved exemption will need to provide a negative PCR test taken within five days prior to their arrival on campus.
5. As part of our attempt …

Update Coronavirus Update 7-30-21, The Coronavirus Planning Team

University Briefings & Virtual Events

It has just been announced that the CDC is including Fairfield County as an area with substantial COVID-19 community transmission. Consequently, as of now we will be putting an indoor masking requirement in place until further notice.

Impact Of Coronavirus Disease 2019 On Prevention And Elimination Strategies For Hepatitis B And Hepatitis C, Syed Tabish Rehman, Hareem Rehman, Shahab Abid

Section of Pulmonary & Critical Care

The coronavirus disease 2019 (COVID-19) pandemic has resulted in significant morbidity and mortality since its first case was discovered in December 2019. Since then, multiple countries have witnessed a healthcare system collapse due to the overwhelming demand for COVID-19 care. Drastic measures have been taken globally in order to curb the spread of the virus. However, those measures have led to the disruption of other aspects of healthcare, increasing the burden due to other medical conditions. We have also stepped back in achieving the ambitious goal set in place by World Health Organization to eliminate viral hepatitis as a public …

Walking The Talk In A Vaccine Study, Carl P. Fictorie

Faculty Work Comprehensive List

"Scientists and engineers of all religious stripes and colors have helped bring about the amazing advances in science and technology that have improved our lives and well-being over the past few hundred years.."

Posting about ­­­­­­­­science as a reliable tool for understanding from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/walking-the-talk-in-a-vaccine-study/

Post-Acute Sequelae Of Covid-19 (Pasc): Association With Inflammation And Autoimmunity, Raghava S. Ambadapoodi, Fnu Deepti, Javaria Anwer Mbbs, Rafael Fernandez-Botran

The University of Louisville Journal of Respiratory Infections

It has become increasingly evident that a high percentage of patients that recover from acute COVID-19 infection continue to suffer from a variety of persistent symptoms even months after viral clearance, the most common ones being fatigue, dyspnea, anosmia, dysgeusia, cognitive dysfunction, and psychological problems, including anxiety and depression. This syndrome, known as Post-acute sequelae of COVID-19 (PASC), can severely affect the life quality and represents an important health care concern. The exact causes for the symptoms observed in patients with PASC remain to be adequately characterized, but are likely to be associated with multiple factors, including residual disease and/or …

Griffithsin And Carrageenan Combination Results In Antiviral Synergy Against Sars-Cov-1 And 2 In A Pseudoviral Model, Sahar Alsaidi, Nadjet Cornejal, Oneil Mahoney, Claudia Melo, Neeharika Verma, Thierry Bonnaire, Theresa Chang, Barry R. O'Keefe, James Sailer, Thomas M. Zydowsky, Natalia Teleshova, José A. Fernández Romero

Publications and Research

Over 182 million confirmed cases of COVID-19 and more than 4 million deaths have been reported to date around the world. It is essential to identify broad-spectrum antiviral agents that may prevent or treat infections by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but also by other coronaviruses that may jump the species barrier in the future. We evaluated the antiviral selectivity of griffithsin and sulfated and non-sulfated polysaccharides against SARS-CoV-1 and SARS-CoV-2 using a cytotoxicity assay and a cell-based pseudoviral model. The half-maximal cytotoxic concentration (CC50) and half-maximal effective concentration (EC50) were determined for each compound, using a dose-response-inhibition …

Acceptance Of Covid-19 Vaccine In Pakistan: A Nationwide Cross-Sectional Study, Mohammad Aadil Qamar, Omar Irfan, Rubaid A. Dhillon, Areesh Bhatti, Mir Ibrahim Sajid, Safia Awan, Wajiha Rizwan, Ali Bin Sarwar Zubairi, Zouina Sarfraz, Javaid Ahmed Khan

Department of Paediatrics and Child Health

Introduction: The coronavirus disease 2019 (COVID-19) vaccine is available across various countries worldwide, with public-private partnerships ensuring all individuals are vaccinated through a phased approach. Irrespective of the geographical spread, several myths pertaining to the COVID-19 vaccine have stemmed, ultimately limiting the national administration of vaccines and rollouts. This study assessed the acceptance of the COVID-19 vaccine among the general public in Pakistan.
Methods: A pre-validated questionnaire was administered from January 2021 to February 2021 to assess the public attitude and acceptance of the COVID-19 vaccine. Logistic regression analyses were run to identify factors associated with the acceptance among the …

Coronavirus Update For July 23, 2021, The Coronavirus Planning Team

University Briefings & Virtual Events

One thing we have learned during this 18-month battle with COVID-19 is that things are constantly changing and, if we want to stay safe, we need to keep up with the latest news. We are aware of the recent rise in COVID Delta variant cases around the country, and in the state, as well as the number of our athletic and clinical partners who are now requiring the vaccine. As a result, and in consultation with state and local health officials, we have made the decision to mandate COVID-19 vaccinations for all students, faculty and staff who plan to be …

Informing Viral Surveillance Of Oropouche Virus: An Emerging Arbovirus, Christine E. Walsh

LSU Master's Theses

Arboviruses are viruses transmitted by hematophagous arthropod vectors. Many of these viruses pose a threat to human health. While some infections may be asymptomatic, others may produce febrile illness, or manifest in life threatening conditions. Symptomatic diagnosis of patients with generalized febrile illness can be confounded due to the various diseases that present clinically in the same manner, and a lack of available diagnostic tests. Surveillance efforts can be used to create awareness about the prevalence of neglected tropical arthropod-borne pathogens, such as Oropouche virus (OROV), and inform preparedness measures for disease outbreaks (SURVEILLANCE SENTENCE). OROV is an arbovirus and …

Covid-19 Newsletter (Vol. 81), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

How To Clean Electronic Items To Prevent Coronavirus (Covid-19), Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages developed in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment.This infographic provides facts about cleaning electronics.

Follow These Procedures For Cleaning Fruits And Vegetables - Lettuce And Other Leafy Greens And Root Vegetables, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages developed in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This fact sheet provides information about cleaning lettuce and other leafy greens and root vegetables.

Follow These Procedures For Cleaning Fruits And Vegetables - Tender Fruits And Vegetables, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 Prevention messages developed in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This fact sheet provides information about cleaning tender fruits and vegetables such as tomatoes, ripe stone fruits, mushrooms, and berries.

Follow These Procedures For Cleaning Fruits And Vegetables - Sturdy Fruits And Vegetables, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages developed in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This fact sheet provides information about cleaning sturdy fruits and vegetables such as green beans, asparagus, cucumbers, and melons.

How Long Can The Coronavirus (Covid-19) Survive?, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages developed in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This fact sheet provides information about the survival times of the virus.

What Can You Do To Prevent Spreading The Coronavirus (Covid-19)?, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This fact sheet provides information on practices to prevent disease.

What Household Cleaning Products Effectively Prevent The Coronavirus (Covid-19)?, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This fact sheet provides information about household cleaning products that prevent disease.

Covid-19 Deliveries: Maternal Features And Neonatal Outcomes, Viviana Zlochiver, Blair Tilkens, Ana Cristina Perez Moreno, Fatima Aziz, M. Fuad Jan

Journal of Patient-Centered Research and Reviews

Integrated, data-driven criteria are necessary to evaluate delivery outcomes in pregnancies affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the ongoing COVID-19 pandemic. This study analyzed maternal demographics, clinical characteristics, treatments, and delivery outcomes of 85 ethnically diverse, adult pregnant women who tested positive for SARS-CoV-2 at the time of delivery. Median maternal and gestational ages were 27 years (interquartile range [IQR]: 23–31) and 39 weeks (IQR: 37.3–40.0), respectively. Of the 85 SARS-CoV-2–positive participants, 67 (79%) had no COVID-19 symptoms at the time of routine COVID-19 admission testing, 14 (16%) reported mild COVID-19 symptoms, and 4 (5%) presented …

Follow These Procedures For Cleaning Fruits And Vegetables, Celina Wille, Teresa Hunsaker

All Current Publications

This infographic is part of a series of eight graphically depicted COVID-19 prevention messages available in English and Spanish, covering virus survival times, personal prevention practices, use of homemade cleaning products, and techniques to maintain a virus-free personal and home environment. This infographic provides facts about cleaning fruits and vegetables.

Preprints In Times Of Covid19: The Time Is Ripe For Agreeing On Terminology And Good Practices, Raffaella Ravinetto, Céline Caillet, Muhammad H. Zaman, Jerome Amir Singh, Philippe J. Guerin, Aasim Ahmad, Carlos E. Durán, Amar Jesani, Ana Palmero, Laura Merson

Section of Nephrology

Over recent years, the research community has been increasingly using preprint servers to share manuscripts that are not yet peer-reviewed. Even if it enables quick dissemination of research findings, this practice raises several challenges in publication ethics and integrity. In particular, preprints have become an important source of information for stakeholders interested in COVID19 research developments, including traditional media, social media, and policy makers. Despite caveats about their nature, many users can still confuse pre-prints with peer-reviewed manuscripts. If unconfirmed but already widely shared first-draft results later prove wrong or misinterpreted, it can be very difficult to "unlearn" what we …

Risk Of Infection And Transmission Of Sars-Cov-2 Among Children And Adolescents In Households, Communities And Educational Settings: A Systematic Review And Meta-Analysis, Omar Irfan, Jiang Li, Kun Tang, Zhicheng Wang, Zulfiqar Ahmed Bhutta

Woman and Child Health

Background: There is uncertainty with respect to SARS-CoV-2 transmission in children (0-19 years) with controversy on effectiveness of school-closures in controlling the pandemic. It is of equal importance to evaluate the risk of transmission in children who are often asymptomatic or mildly symptomatic carriers that may incidentally transmit SARS-CoV-2 in different settings. We conducted this review to assess transmission and risks for SARS-CoV-2 in children (by age-groups or grades) in community and educational-settings compared to adults.
Methods: Data for the review were retrieved from PubMed, EMBASE, Cochrane Library, WHO COVID-19 Database, China National Knowledge Infrastructure (CNKI) Database, WanFang Database, Latin …