Diseases Commons^™

Investigation Of Selenium Status In Hypo-, Hyper- And Euthyroid Children, Ping Sun

Chemistry & Biochemistry Theses & Dissertations

Recently, it has been reported that human type I iodothyronine deiodinase, an enzyme important in the conversion of T₄ to T₃ , is a selenoenzyme. Several studies have reported alterations in plasma selenium level in hypo- and hyperthyroid patients.

Using polarized Zeeman-effect atomic absorption spectroscopy, we measured selenium, zinc, copper and manganese concentrations in the plasma and/or red blood cells in children with or without thyroid disease being seen at the outpatient clinic at Children's Hospital of the King's Daughters. Children with thyroid disease were subdivided into untreated, treated and nonresponsive groups. Data were analyzed using Student's t-test …

Longitudinal Study Of Plasma And Erythrocyte Selenium Levels In Type I Diabetic Children During Development And Treatment Of Ketoacidosis, Pi-Hsia Fan

Chemistry & Biochemistry Theses & Dissertations

Most studies on the biological activity of selenium have focused on its role at the active site in the ubiquitous enzyme, glutathione peroxidase (GSH-Px) which catalyzes the removal of hydrogen peroxide and organic hydroperoxides (1). A connection between selenium deficiency and a wide range of diseases in animals and humans has been reviewed (2). Development of various forms of human cancer (3), failure of the immune system (4), as well as some cardiovascular diseases (5) have been reported or suspected to correlate with selenium deficiency. However, the physiological function of selenium in these different diseases is not fully understood, and …

Development Of A Questionnaire To Assess Knowledge In Women With Gestational Diabetes, Caron Mclarty

Theses : Honours

Women with a history of gestational diabetes mellitus (GDM) have a significantly increased risk of developing diabetes mellitus in later life. A lifestyle which includes healthy eating habits, weight control, regular exercise, and stress management has been associated with preventing or delaying the onset of diabetes mellitus and its associated complications. To care for themselves women require educati9n about and knowledge of strategies that have been associated with preventing diabetes. An essential part of education is knowledge assessment Women with GDM have been largely overlooked in the development of instruments to measure knowledge of diabetes. Orem's general theory of nursing …

Clover Infertility Of Sheep : Continuing Problem, N R. Adams, Keith Croker

Journal of the Department of Agriculture, Western Australia, Series 4

Some varieties of subterranean clover, notably Dinninup, Dwalganup and Yarloop, contain compounds which act like the female sex hormone oestrogen. These plant oestrogens, or "phyto-oestrogens", interfere with the fertility of sheep and depress the percentage of lambs born.

Over the past 10 years our understanding of clover infertility has increased, and we can now gauge the extent of this residual problem. In fact, there is a widespread but low-level incidence of infertility which does not greatly affect individial farms but which has an important impact on the State's sheep production.

Magnesium, Copper And Zinc Concentrations In Blood From Children With Diabetes Mellitus, Linda Lowers Jenkins

Chemistry & Biochemistry Theses & Dissertations

Trace element levels in blood from diabetic children were investigated and compared to control children. Plasma, erythrocyte, mononuclear and polymorphonuclear cells were analyzed for magnesium, copper, and zinc content. Leukocyte separation was performed by density gradient centrifugation on Ficoll-Hypaque, followed by washing steps to remove platelet contamination and hypotonic lysis to remove red cell contamination. Polarized Zeeman-effect atomic absorption spectroscopy was used for trace metal analysis.

Decreased plasma magnesium levels were observed in the diabetic children. This finding is well documented and probably due to increased urinary magnesium loss from glycosuria. Lymphocyte magnesium levels in the diabetic children were also …

The Effect Of Adrenaline Injection On Glycogenolysis And Glycogenesis In Rat Livers, Virginia Mary Zingsheim

Bachelors’ Theses

Present day knowledge concerning the liver is derived from many sources and the accumulation of many methods of investigation. Sugar, which is needed by the body for energy, is stored in the liver as glycogen. Claude Bernard (26), an eminent physiologist, was the first to suspect that carbohydrates were stored in the liver. Faulty glycogen synthesis and hydrolysis results in one of our most widespread diseases, diabetes. Thus, many biochemists and physiologists have tried to find the mechanism of the process, and the primary and secondary facts which affect glycogenesis and glycogenolysis. Although the chemical secretions and hormones of such …

Insulin, Walter Zeit

Bachelors’ Theses

The objectives of this paper are: 1. A review of the discovery of insulin. 2. A discussion of the nature of insulin. 3. A discussion of the distribution of insulin. 4. A study of the development of the pancreas. 5. The presentation of a problem for further investigation.