Dietetics and Clinical Nutrition Commons^™

Development Of A Nicotinic Acetylcholine Receptor Nachr Α7 Binding Activity Prediction Model, Sugunadevi Sakkiah, Carmine Leggett, Bohu Pan, Wenjing Guo, Luis G. Valerio Jr., Huixiao Hong

United States Food and Drug Administration: Publications

Despite the well-known adverse health effects associated with tobacco use, addiction to nicotine found in tobacco products causes difficulty in quitting among users. Nicotinic acetylcholine receptors (nAChRs) are the physiological targets of nicotine and facilitate addiction to tobacco products. The nAChR-α7 subtype plays an important role in addiction; therefore, predicting the binding activity of tobacco constituents to nAChR-α7 is an important component for assessing addictive potential of tobacco constituents. We developed an α7 binding activity prediction model based on a large training data set of 843 chemicals with human α7 binding activity data extracted from PubChem and ChEMBL. The model …

Long-Term Negative Emotional Outcomes Of Warzone Tbi, Jennifer J. Vasterling, Mihaela Aslan, Susan P. Proctor, John Ko, Xenia Leviyah, John Concato

United States Food and Drug Administration: Publications

Objective: Many veterans of the Iraq and Afghanistan Wars have experienced traumatic brain injury (TBI). Although prior work has examined associations between TBI and development of psychi- atric syndromes, less is known about associations between TBI and component emotions constituting these syndromes, especially in the long term. The purpose of this study was to examine the long-term emotional consequences of deployment-related TBI.

Methods: As part of VA Cooperative Studies Program #566, we assessed a sample of n1⁄4456US Army soldiers prior to an index deployment to Iraq, and again an average of 8.3 years (SD1⁄42.4years) after their deployment for a long-term …

Association Between Breastfeeding And Child Stunting In Mexico, Ana Paola Campos, Mireya Vilar-Compte, Summer Sherburne Hawkins

Department of Public Health Scholarship and Creative Works

Background: Globally, the prevalence of child stunting has been decreasing over the past decades. How-ever, in low-and middle-income countries such as Mexico, stunting is still the most prevalent form of undernutrition affecting a large number of children in the most vulnerable conditions. Breastfeeding has been identified as one of the key affordable and modifiable maternal health behaviors protecting against child stunting. Objective: To examine the association between breastfeeding (defined as never breastfed, any breast-feeding for <6 months, and any breastfeeding for ≥6 months) and other individual-, household-, and area-level factors with child stunting (defined as length/height-for-age-z-score for sex under –2 standard deviations of the World Health Organization child growth standards’ median) in Mexico. Methods: Secondary data analysis using the 2012 Mexican Health and Nutrition Survey, which allowed representativeness of rural and urban areas at national level and among 4 regions in Mexico. Our subset included data on 2,089 singleton Mexican children aged 6–35 months with information on previously identified risk and protective factors for stunting. We conducted fixed-and mixed-effects logistic regression models sequentially controlling for each level of factors. Findings: Overall, 12.3% of children were stunted and 71.1% were breastfed for ≥6 months. Any breast-feeding and being female were consistent protective factors against child stunting across all models. In contrast, child low birthweight, maternal short stature, higher number of children aged <5 years per household, and moderate to severe food insecurity were consistent risk factors for child stunting across all models. Conclusions: According to our findings, efforts to reduce child stunting in Mexico should include prenatal strategies aiming to prevent low birthweight offspring particularly among short-stature women, moderate to severe food insecure households, families with a higher number of children aged <5 years, and indigenous communities. Postnatal components should include multilevel strategies to support breastfeeding.

December 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

World AIDS Day

World AIDS Day is a global initiative to raise awareness, fight stigma, and improve education about HIV, the virus that causes AIDS. Around the world, about 37 million people are living with HIV. In the United States, about 38,500 people get infected with HIV every year and many of which don’t even know they have it. World AIDS Day is a global initiative to raise awareness, fight prejudice, and improve education about HIV and AIDS.

The only way to know if you have HIV is to get tested. It’s important that everyone ages 15 to 65 gets …

November 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

National Diabetes Awareness Month Diabetes is one of the leading causes of disability and death in the United States. One in 10 Americans have diabetes — that’s more than 30 million people. There are also 84 million adults in the United States are at high risk of developing type 2 diabetes.

Depending on your age, weight, and other factors, you may be at higher risk of developing type 2 diabetes. The good news is that making healthy changes can greatly lower your risk. To help prevent type 2 diabetes:

• Watch your weight
• Eat healthy
• Get more physical activity

September 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

National Childhood Obesity Awareness Month

One in 5 children in the United States have obesity. Childhood obesity puts kids at risk for health problems that were once seen only in adults, like type 2 diabetes, high blood pressure, and heart disease.

The good news is that childhood obesity can be prevented. In honor of National Childhood Obesity Awareness Month, SWOSU encourages your family to make healthy changes together.

• Get active outside! Walk around the neighborhood, go on a bike ride, or play basketball at the park.
• Limit screen time. Keep screen time (time spent on the computer, watching TV, or …

August 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

National Immunization Month

We all need shots (vaccines) to help protect us from serious diseases. This protection is called immunization and it is in place to help keep our community safe. Shots can prevent serious diseases like the flu, measles, and pneumonia. It’s important to know which shots you need and when to get them.

July 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

UV Safety Month

Summer has arrived and while the sun is shining bright it's a golden time to highlight July as UV Safety Awareness Month! We all love to take in those warm summer rays, but everyone must remember to protect their skin and eyes from the damaging effects of the sun.

June 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

National Safety Month

Injuries are the leading cause of death for Americans ages 1 to 44. The good news? Everyone can get involved to help prevent injuries. During National Safety Month, SWOSU is working with community members to help reduce the risk of injuries. This June, we encourage you to learn more about important safety issues like preventing poisonings, transportation safety, and slips, trips, and falls.

May 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Physical Fitness and Sports Month

Southwestern Oklahoma State University is supporting the President’s Council on Sports, Fitness & Nutrition in honor of National Physical Fitness and Sports Month. During the month of May, we challenge all adults to get active every day!

Abstracts From The 25th Annual Health Care Systems Research Network Conference, April 8–10, 2019, Portland, Oregon

Journal of Patient-Centered Research and Reviews

The Health Care Systems Research Network (HCSRN) is made up of nonprofit health systems with embedded research departments whose scientists are dedicated to public domain research. The network’s annual conference serves as a forum for research teams to disseminate study findings, stimulate new collaborations, and share insights about conducting research in real-world care settings. Abstracts accepted for presentation at HCSRN 2019 are published in this supplement of Journal of Patient-Centered Research and Reviews, the official scientific journal of the conference.

April 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

National Public Health Week

Join in observing National Public Health Week from April 1-7, 2019 and become part of a growing movement to create the healthiest nation in one generation. During the week, we will celebrate the power of prevention, advocate for healthy and fair policies, share strategies for successful partnerships and champion the role of a strong public health system. Each day of NPHW 2019 will focus on a public health topic. Hoping each topic will spark new conversations and engage new participants in the community. Follow along at this link to see daily themes and ways each of …

March 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

The Bulldog Wellness Committee has 1 standing desk available to be loaned out for a 4 month trial basis. The desk has a two-tiered design with separate keyboard/mouse deck and a spring-assisted lift mechanism that allows for easy access when either sitting or standing. Contact Christina Darras at (580) 774-3159 or email [email protected] to reserve your desk today.

February 2019, Sarah Yount

Wellness Committee Minutes

No abstract provided.

Market Claims And Efficacy Information In Direct‐To‐Consumer Prescription Drug Print Advertisements, Kathryn J. Aikin Phd, Kevin R. Betts Phd, Aysha Keisler Phd, Kathryn Schaefer Ziemer Phd

United States Food and Drug Administration: Publications

This study examined the impact of “New” and “#1 Prescribed” market claims and quantitative efficacy information on perceptions of a hypothetical prescription drug in a direct‐to‐consumer (DTC) print advertisement. We examined two market claims (New and #1 Prescribed), two efficacy levels (higher and lower), and a control condition without this information. Participants with diabetes were randomized to review one ad version and asked their perceptions of the ad's message, the drug's benefits, side effects and risks, doctors' opinions about the drug, and behavioral intention to use the drug, as well as recall and recognition of drug benefits and risks. Results …

Youth Perception Of Harm And Addictiveness Of Tobacco Products: Findings From The Population Assessment Of Tobacco And Health Study (Wave 1), David R. Strong, Karen Messer, Martha White, Yuyan Shi, Madison Noble, David B. Portnoy, Alexander Persoskie, Annette R. Kaufman, Kelvin Choi, Charles Carusi, Maansi Bansal-Travers, Andrew Hyland, John Pierce

United States Food and Drug Administration: Publications

Purpose: We provide a US national assessment of youth perceptions of the harm and addictiveness of six separate tobacco products, identifying a continuum of perceived harm associated with a range of products in relation to patterns of current use, former use, and susceptibility to use tobacco products.

Methods: We evaluated youth respondents (N=13,651) ages 12–17 from Wave 1 (2013–2014) of the Population Assessment of Tobacco and Health (PATH) Study. Analyses (2015–2016) focused on refining mea- sures of perceived harm for each product and delineating youth characteristics (demographic, tobacco use status) associated with beliefs about the harmfulness and addictiveness of tobacco …

Associations Of Risk Factors Of E-Cigarette And Cigarette Use And Susceptibility To Use Among Baseline Path Study Youth Participants (2013–2014), Michael D. Sawdey, Hannah R. Day, Blair Coleman, Lisa D. Gardner, Sarah E. Johnson, Jean Limpert, Hoda T. Hammad, Macieji L. Goniewicz, David B. Abrams, Cassandra A. Stanton, Jennifer L. Pearson, Annette R. Kaufman, Heather L. Kimmel, Cristine D. Delnevo, Wilson M. Compton, Maansi Bansal-Travers, Raymond S. Niaura, Andrew Hyland, Bridget K. Ambrose

United States Food and Drug Administration: Publications

Introduction: Improved understanding of the distribution of traditional risk factors of cigarette smoking among youth who have ever used or are susceptible to e-cigarettes and cigarettes will inform future longitudinal studies examining transitions in use.

Methods: Multiple logistic regression analysis was conducted using data from youth (ages 12–17 years) who had ever heard of e-cigarettes at baseline of the PATH Study (n = 12,460) to compare the distribution of risk factors for cigarette smoking among seven mutually exclusive groups based on ever cigarette/e-cigarette use and sus- ceptibility status.

Results: Compared to committed never users, youth susceptible to e-cigarettes, cigarettes, or …

Selection And Consumption Of Lunches By National School Lunch Program T Participants, Janet G. Peckham, Jaclyn D. Kropp, Thomas A. Mroz, Vivian Haley-Zitlin, Ellen M. Granberg

United States Food and Drug Administration: Publications

The Healthy, Hunger-Free Kids Act of 2010 requires schools participating in the National School Lunch Program (NSLP) to offer a variety of healthy food options each day. Using digital photography data collected from two suburban elementary schools in the spring of 2013, we examine NSLP participant's selection and consumption of all five NSLP lunch components ((1) milk, (2) vegetable, (3) fruit, (4) meat/meat alternate (MA), and (5) grain). We use logit regressions to analyze the selection of the various lunch components by race/ethnicity, gender, grade, and household income level. In addition, ordinary least squares regressions are used to analyze the …

Examining The Role Of Menthol Cigarettes In Progression To Established T Smoking Among Youth, James Nonnemaker, Shari P. Feirman, Anna Macmonegle, Bridget K. Ambrose, Kia J. Jackson, Megan J. Schroeder, Alexandria A. Smith, William Ridgeway, Olga Rass

United States Food and Drug Administration: Publications

Background: Menthol, a flavoring compound added to cigarettes, makes cigarettes more appealing to youth and inexperienced smokers and increases cigarettes' abuse liability. However, limited studies are available on menthol's role in smoking progression.

Methods: To assess the association between menthol in cigarettes and progression to established smoking, we used five waves of data from the Evaluation of Public Education Campaign on Teen Tobacco Cohort Study, a nationally representative longitudinal survey of U.S. youth conducted as part of “The Real Cost” evaluation. We used discrete time survival analysis to model the occurrence of two event outcomes—progression to established, current smoking and …

U.S. Adult Perceptions Of The Harmfulness Of Tobacco Products: Descriptive T Findings From The 2013–14 Baseline Wave 1 Of The Path Study, Geoffrey T. Fong, Tara Elton-Marshall, Pete Driezen, Annette R. Kaufman, K. Michael Cummings, Kelvin Choi, Jonathan Kwan, Amber Koblitz, Andrew Hyland, Maansi Bansal-Travers, Charles Carusi, Mary E. Thompson

United States Food and Drug Administration: Publications

Introduction: This study is the first nationally representative survey of U.S. adults (18+) to examine perceptions of the relative harms of eight non-cigarette tobacco products.

Methods: Data are from Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study Adult Questionnaire, a nationally representative study of 32,320 adults in the United States conducted from September 2013 to December 2014.

Results: 40.7% of adults believed that electronic cigarettes were less harmful than cigarettes, and 17.8% of adults believed that hookah was less harmful than cigarettes. Those less knowledgeable about the health risks of smoking were more likely to believe …

At Risk Alcohol Consumption With Smoking By National Background: Results From The Hispanic Community Health Study/Study Of Latinos, Frank C. Bandiera, Eliseo J. Pérez-Stable, Folefac Atem, Raul Caetano, Denise C. Vidot, Marc D. Gellman, Elena L. Navas-Nacher, Jianwen Cai, Gregory Talavera, Neil Schneiderman, Robert Kaplan

United States Food and Drug Administration: Publications

Introduction: Tobacco smoking and binge or excess drinking are unhealthy behaviors that frequently co-occur. Studies of Hispanics/Latinos have mostly been of Mexican Americans although there are substantial differences in smoking and drinking by heritage background. Associated with co-use by 5 subpopulations.

Methods: Cross-sectional data of 16,412 Hispanics/Latinos from Miami, the Bronx, Chicago and San Diego collected between 2008 and 2011 as part of the HCHS/SOL were analyzed. Smoking and alcohol consumption and demographic data were measured by self-report. Prevalence of smoking and alcohol consumption and co-use were reported. Logistic regression models examined the odds of co-use of smoking and binge …

Comparing Methods For Clinical Investigator Site Inspection Selection: A Comparison Of Site Selection Methods Of Investigators In Clinical Trials, Nicholas Hein, Elena Rantou, Paul Schuette

United States Food and Drug Administration: Publications

Background During the past two decades, the number and complexity of clinical trials have risen dramatically increasing the difficulty of choosing sites for inspection. FDA’s resources are limited and so sites should be chosen with care.

Purpose To determine if data mining techniques and/or unsupervised statistical monitoring can assist with the process of identifying potential clinical sites for inspection.

Methods Five summary-level clinical site datasets from four new drug applications (NDA) and one biologics license application (BLA), where the FDA had performed or had planned site inspections, were used. The num- ber of sites inspected and the results of the …

January 2019, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Making Your Resolutions Really Work

New Year’s resolutions are slightly out of favor — airily dismissed as a waste of time, given their high failure rate. But there remains something compelling about the onset of a brand new year for reflecting on changes that would improve your life. To provide advice on ways to make resolutions that will actually come to fruition,

December 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Money savers for Holiday Shoppers

We hate to be negative this time of year, but gift-giving can get expensive! How to pay for all those gifts? Here are a few suggestions…

Healthy Holiday Habits

Travel, parties, big meals and snack foods at the office all create a challenging environment for eating healthy. Add in several days of travel with little scheduled physical activity, and it becomes a real effort to stay on track. Here are some helpful hints to help keep your holidays healthy!

November 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Healthier Dishes to Serve This Thanksgiving

This year, why not make Thanksgiving not only delicious but also a health-boosting experience that’s truer to the origins of the holiday? For most of us, our traditional Thanksgiving meal has shifted away from the natural foods enjoyed by the 17th-century celebrants. But it’s not that difficult to get back to preparing delicious food that is fresh from the harvest…and packed with nutrition.

October 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Walking Club

The SWOSU Walking Club is meeting every MWF, 12:10 pm, at the Wellness Center. Fit exercising into your workday with a 30-40-minute walk and receive the benefits of social support, stress relief, and renewed energy.

SWOSU Fall Pool Hours

Monday-Friday 6:00-8:00 a.m. 12:00-2:00 p.m. 5:00-7:00 p.m. (except Tuesday)

Water Aerobics

Monday-Wednesday 6:00–7:00 p.m. Thursday 5:00-6:00 p.m.

September 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

Walking Club
The SWOSU Walking Club is meeting every MWF, 12:10 pm, at the Wellness Center. Fit exercising into your workday with a 30-40-minute walk and receive the benefits of social support, stress relief, and renewed energy.

SWOSU Fall Pool Hours
Monday-Friday
6:00-8:00 a.m. 12:00-2:00 p.m.
5:00-7:00 p.m. (except Tuesday)

Water Aerobics
Monday-Wednesday 6:00–7:00 p.m.
Thursday 5:00-6:00 p.m.

July 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

SWOSU Rural Health Center will be offering the National Diabetes Prevention Program (NDPP) again for those with prediabetes or at high risk for type 2 diabetes starting in September. The program has proven to cut the risk for type 2 diabetes in half. Please complete the following questionnaire to see if you qualify! https://swosu.formstack.com/forms/prescreening_questionnaire_dpp

June 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

No abstract provided.

May 2018, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

No abstract provided.