Periodontics and Periodontology Commons^™

Mangosteen Peel Extract Vs Tetracycline Gel In Treatment Of Periodontal Abscess In Type-2 Diabetes – A Randomized Clinical Trial, Ksv Ramesh, Itha Joshna, Gautami S. Penmetsa, Gottumukkala Nvs Sruthima, Pasupuleti Mohan Kumar, Boddeda Anusha, Sathya Valli

Journal of Dentistry Indonesia

Herbal products are gaining popularity due to their diverse biological action and safety. Mangosteen peel extract has antibacterial and anti-inflammatory properties and can be used to treat periodontal diseases. Objective: To compare the efficacy of mangosteen peel extract and tetracycline gel as an adjunct to non-surgical management of periodontal abscess in type-II diabetes patients. Methods: This was a double blinded, randomized clinical trial included 20 Patients with Type-II diabetes. Both test and control groups received NSPT followed by adjunctive local application of mangosteen peel extract and tetracycline gel. Clinical parameters i.e., Probing depth (PPD), Clinical attachment level (CAL), …

Comparison Of The Factors Affecting Smile Esthetics With The Patient And Physician Perceptions Using The Smile Esthetic Index, Dilek Özkan Şen, Zeynep Taştan Eroğlu,, Osman Babayiğit,, Fatma Uçan Yarkaç

Journal of Dentistry Indonesia

Objective: This study aimed to evaluate the smile esthetics of individuals and the factors affecting it using the smile esthetic index (SEI) and compare them with the patient’s perception of smile. Methods: Seventy-six patients consisting of 44 females and 32 males who presented to for routine periodontal treatments were included in study. The smile esthetics were evaluated by three researchers on the photographs taken from the patients. The visual analog scala was used for the subjective evaluation of smile esthetics. Results: According to the results obtained from the study, the average of the SEI total scores was …

Recent Advances In Nanomaterial-Based Biosensor For Periodontitis Detection, Mohammad Hosseini Hooshiar, Masoud Amiri Moghaddam, Mohammad Kiarashi, Athraa Y Al-Hijazi, Abbas Fadel Hussein, Hareth A Alrikabi, Sara Salari, Samar Esmaelian, Hassan Mesgari, Saman Yasamineh

Faculty, Staff and Student Publications

Periodontitis, a chronic inflammatory condition caused by bacteria, often causes gradual destruction of the components that support teeth, such as the alveolar bone, cementum, periodontal ligament, and gingiva. This ultimately results in teeth becoming loose and eventually falling out. Timely identification has a crucial role in preventing and controlling its progression. Clinical measures are used to diagnose periodontitis. However, now, there is a hunt for alternative diagnostic and monitoring methods due to the progress of technology. Various biomarkers have been assessed using multiple bodily fluids as sample sources. Furthermore, conventional periodontal categorization factors do not provide significant insights into the …

Association Of F. Alocis And D. Pneumosintes With Periodontitis Disease Severity And Red Complex Bacteria, Hawaabi F.M. Shaikh, Pratima U. Oswal, Manohar Suresh Kugaji, Sandeep S. Katti, Kishore Gajanan Bhat, Eswar Kandaswamy, Vinayak M. Joshi

School of Dentistry Faculty Publications

Oral biofilms are considered the principal etiological agent in the development of periodontitis. Novel species that may contribute to periodontitis and dysbiosis have been identified recently. The study aims to evaluate the presence of F. alocis and D. pneumosintes in healthy and diseased patients and their association with clinical parameters and with red complex bacteria. The study included 60 subjects, with 30 patients each in the healthy and periodontitis groups. The clinical parameters were noted, and samples were subjected to DNA extraction followed by a polymerase chain reaction. Statistical analysis was performed using the Graph Pad Prism software. Results: F. …

Caries Management For The Modern Era

Journal of the Macomb Dental Society

This month's Meeting lecture reviewed non-restorative versus restorative management of caries based on science, evidence based research and leading expert guidelines with Dr. Margherita Fontana. Dr. Fontana stressed that caries risk assessments done with patients give insights but that should not be the end of the conversation.

Efficacy Of Photodynamic Therapy As An Adjunct To Scaling And Root Planing On Clinical Parameters And Microbial Composition In Subgingival Plaque Of Periodontitis Patients: A Split-Mouth Randomized Clinical Trial, Paul W. Bible, Min Nie, Peien Huang, Peiyao Peng, Daonan Shen, Lei Zhao, Duan Jiang, Yuqin Shen, Lai Wei, Jingmei Yang, Jun Wang, Yafei Wu

Computer Science Faculty publications

Background

The aim of this study was to assess the efficacy of photodynamic therapy (PDT) as an adjunct to scaling and root planing (SRP) on clinical parameters and microbial composition in subgingival plaque of periodontitis patients.

Methods

Seventeen patients were included in this split-mouth randomized clinical trial. Sites with probing pocket depth (PPD) ≥5 mm in combination with bleeding on probing in different quadrants were randomized into the control group, the group with a single PDT application right after SRP, and the group with three repeated PDT applications 1 week after SRP. The subgingival plaque was collected for 16S rRNA …

Efficacy Of Suture Versus Sutureless Technique After Periodontal Flap Surgery – A Split Mouth Study, Saranya M

Annual Research Symposium

Suturing is an integral part of periodontal flap surgery, but it has disadvantages such as difficulty in maintaining oral hygiene, increased post-operative discomfort, and higher infection rate. To overcome these problems, a search for an alternative like tissue adhesives, possibly a sutureless technique has been experimented. The aim of the study was to compare the stability & healing properties after periodontal flap surgery using tissue adhesive and surgical sutures.

I-Prf : A Smart Cell Scaffold, Dr.Lochini Suriya

Annual Research Symposium

In regenerative dentistry, platelet rich plasma (PRP) has been used as a supra-physiological concentration of autologous growth factors capable of encouraging tissue regeneration. Despite this, there have been concerns raised about the use of anticoagulants, which are known to impair wound healing. In this work, a liquid formulation of platelet rich fibrin (PRF) called injectable-PRF (I-PRF) was studied without the need of anti-coagulants .

The Transformative Potential Of Ligaplants In Replicating Natural Tooth Connections, Mohan Prasad, Mohan Muthu Kumar

Annual Research Symposium

Over the past decade, dental implants have become the gold standard in tooth replacement, with osseointegrated implants reigning supreme. However, these implants present certain limitations, notably the absence of the periodontal ligament (PDL). In response to this challenge, innovative periodontal ligament implants, known as ligaplants, have emerged. By combining tissue engineering principles with cutting-edge implant materials, ligaplants offer a promising alternative to traditional implants, showcasing superior biological performance and potentially extending prosthetic life.Dental implantology has witnessed a transformative shift over the last ten years, with osseointegrated implants dominating the landscape of tooth replacement. Despite their widespread adoption, these implants face …

Clinical, Radiographic And Biochemical Evaluation Of One-Piece Vs Two-Piece Single Implants After 5 Years Of Functional Loading, Ippolito Caputo

Annual Research Symposium

The aim of this study was to compare the clinical and radiographic conditions and the expression of proinflammatory cytokines in peri-implant crevicular fluid (PICF) of two-piece/bone level (TP/BL) versus one-piece/tissue level (OP/TL) single implants with a laser-microgrooved collar after at least 5 years of functional loading.

Influence Of Abutments Surface (Machined Vs. Laser-Microgrooved) In Soft-Tissue Response During One Year Of Function: Clinical And Biochemical Outcomes Of A Rct With Split-Mouth Design, Elisa Maccari

Annual Research Symposium

To evaluate peri-implant soft tissue behaviour around machined vs laser-microgrooved implants/healing/prosthetic abutments during 1 year of function by assessing IL-6, IL-1b and MMP-8 levels in peri-implant crevicular fluid (PICF).

Mandibular Bone Block Graft For Localised Ridge Augmentation- A Case Report, Teena Selvaraj

Annual Research Symposium

Dental implants in the anterior mandible is a challenge for clinicians because of patients exacting esthetic demands and difficult pre-existing anatomy. The placement of endosteal implants requires adequate bone volume for successful osseointegration. When themorphology of the bone does not allow proper implant placement, there are various bone augmentation procedures like bone grafts, which may be autografts, xenografts, allografts or alloplasts aids in reconstruction of the residual alveolar ridge for ideal implant placement. Among various bone grafts, the autogenous bone graft is still the “gold standard” for bone augmentation procedures. The symphysis region can act as an excellent source of …

Comprehensive Assessment Of Socket Preservation Techniques: Exploring The Effectiveness Of Titanium-Prf And Demineralized Freezed Dried Bone Allograft In Implant Dentistry, Surthi Senthil

Annual Research Symposium

To evaluate the effectiveness of Titanium-prepared Platelet rich Fibrin (T-PRF) gel combined with demineralized freeze-dried bone allograft (dFDBA) for Socket Preservation versus spontaneous healing with the aid of Cone beam computed tomography (CBCT).

Estrogen Level, Osteopenia/Osteoporosis And Periodontal Status In Post Menopausal Women – A Comparative Evaluation, Dr Sanupa S. Madhavan, Dr Anjhana Narayanan

Annual Research Symposium

Osteopenia, Osteoporosis and periodontitis are diseases, which affect a large number of populations across the country and world. Both are silent diseases” which cause bone loss mediated by local and systemic factors. These two diseases also share some risk factors that may interfere with healing.. Estrogen deficiency is the dominant pathogenic factor for osteoporosis in women .Various reports also have linked estrogen deficiency and osteopenia/osteoporosis to increased oral bone resorption , attachment loss and tooth loss .The objective of the study is to analyse and evaluate the condition of periodontal status of twenty five osteopenic/osteoporotic postmenopausal women and their estrogen …

Root Analogue Implants- The New Route, Subhashini Balaguru

Annual Research Symposium

Dental implants are an excellent option for replacing missing teeth. Traditional implants have a cylindrical or tapered geometry with threads along the screw length. The lack of proper congruency between the implant and the socket bone can eventually lead to implant failure due to stability loss and failure in osseointegration. To overcome this problem, novel approaches are being evaluated to manufacture customized root implants. This is expected to reduce the bone and soft-tissue trauma and promote a better primary stability. They do not require bone drilling, sinus lifting, bone augmentation or other traumatic procedures.

Relationship Between Periodontal Disease And Coronary Heart Disease: A Bibliometric Analysis, Xiaowen Bo, Wenpeng Song

Annual Research Symposium

Periodontal disease (PD) and coronary heart disease (CHD) are both prevalent diseases worldwide and cause patients physical and mental suffering and a global burden. Recent studies have suggested a link between PD and CHD, but there is less research in this field from the perspective of bibliometrics. This study aimed to quantitatively analyze the literature on PD and CHD to summarize intellectual bases, research hotspots, and emerging trends and pave the way for future research.

Interplay Of Periodontal Bacterial Metabolites In The Progression Of Coronary Artery Disease: A System Biological Approach, Janakiraman V

Annual Research Symposium

Purpose:

The purpose of this study is to investigate the intricate relationship between periodontal disease (PD) and coronary artery disease (CAD), as evidenced by epidemiological associations. Metalloproteinase inhibitor (TIMP1) plays a pivotal role in cellular signaling, differentiation, cell death, and migration by binding to target metalloproteinases, forming complexes with other molecules (collagenases) to inactivate them. However, the expression of TIMP1 is reduced in both PD and CAD, leading to an upregulation of other metalloproteinases. This research explores the hypothesis that metabolites released from (Porphyromonas gingivalis), a prevalent bacterium in atherosclerotic patients, may inhibit TIMP1, thereby influencing CAD progression. …

Impact Of Non-Surgical Periodontal Treatment On Salivary Hif-1Α In Gingivitis & Periodontitis Patients, Srijanani S

Annual Research Symposium

To estimate and compare the level of salivary HIF-1α in periodontally & systemically healthy volunteers, generalized chronic gingivitis & periodontitis patients before and after non-surgical periodontal treatment.

Exploring The Resilience Of Two Commercial Suturing Materials Subjected To Thermocycling And Chlorhexidine Immersion: An In Vitro Study, Devadharshini Chandrasekar

Annual Research Symposium

To evaluate the durability of two commercially available suture materials (non absorbable Black Braided Silk and absorbable polyglactin 910) subjected to thermocycling after immersing in Chlorhexidine mouthwash.

Diagnostic Detail: Understanding The Impact Of Tooth Rotation In Correcting Mucogingival Defects, Trevor Simmonds Dds, Stephanie M. Chu Dmd, Mike Roig Dmd, Kristian T. Poventud Dmd

The New York State Dental Journal

Introduction: The subepithelial connective tissue graft (S-CTG) is the gold standard in achieving root coverage but is not without limitations. The Acellular Dermal Matrix (ADM) is an alternative source that can compensate for the S-CTG’s limitations. Body: Severe recession type 1 (RT1) defects were treated with a combined approach of autogenous and allogeneic soft tissue grafting, optimizing the benefits of both types of materials, in order to achieve maximum root coverage (MRC). Conclusion: Identifying the anatomical limitations of gingival recession as it relates to tooth rotation and its impact on vascular supply will best prepare both the clinician and patient …

The Use Of Tissue Grafts Associated With Immediate Implant Placement To Achieve Better Peri-Implant Stability And Efficacy: A Systematic Review And Meta-Analysis, Enrico Maria Rondone, Bruno Leitão-Almeida, Miguel Silva Pereira, Gustavo Fernandes, Tiago Borges

MOSDOH Faculty Publications

Background: The goal of this systematic study and meta-analysis was to evaluate the efficacy of hard and/or soft tissue grafts associated with type-1 implants on healing and treatment outcomes. The primary outcomes studied were implant survival rate, pocket depth, marginal periimplant recession, bone loss, bone thickness (volumetric change), interproximal bone level, mesial and distal papilla migration, and radiographic evaluation; and the secondary parameters were Pink Esthetic Score (PES), vertical distance from implant shoulder and bone, Visual Analogue Score (VAS), Implant Stability Quotient (ISQ), and biological complications (fistulas, pain, mucositis, and peri-implantitis). Methods: The PICO strategy was used to formulate the …

Fibroblasts And Osteoblasts Behavior After Contact With Different Titanium Surfaces Used As Implant Abutment: An In Vitro Experimental Study, Jose Henrique Cavalcanti De Lima, Patricia Cristina Matos Robbs, Elena Mavropoulos Oliveira Tude, Piedad N. De Aza, Eleani Maria Da Costa, Antonio Scarano, Juan Carlos Prados-Frutos, Gustavo Fernandes, Sergio Alexandre Gehrke

MOSDOH Faculty Publications

Background: The goal of this in vitro study was to compare three different surfaces: two types of implant surfaces commercially available ([a] smooth/machined and [b] acid-treated surface) versus (c) anodized surface. Discs were manufactured with commercially pure titanium (CP) grade IV, which were subsequently analyzed by scanning microscopy and fibroblastic and osteoblastic cell cultures. Methods: Ninety-nine discs (5 × 2 mm) were manufactured in titanium grade IV and received different surface treatments: (i) Mach group: machined; (ii) AA group: double acid etch; and (iii) AN group: anodizing treatment. Three discs from each group were analyzed by Scanning Electron Microscopy (SEM) …

Minimally Invasive Periodontal Regeneration With The Buccal Approach: A Systematic Review And Meta-Analysis Of Clinical Studies, Elisa Pasqualini, Filipe Castro, Denise Curado, Ana Martelete, Artak Heboyan, Muhammad H. Saleh, Juliana Campos Hasse Fernandes, Gustavo Fernandes

MOSDOH Faculty Publications

OBJECTIVE: The aim of this study was to investigate clinical periodontal parameters after treatment using the Minimally Invasive Surgical Technique (MIST), Modified Minimally Invasive Surgical Technique (M-MIST), and/or any technique for papilla preservation, such as Entire Papilla Preservation (EPP), modified-papilla preservation technique (M-PPT), or simplified-papilla preservation technique (SPPT). METHODS: The focus question was “For patients with periodontal intrabony defects (P), what is the best minimally invasive regenerative approach (I), comparing MIST, M-MIST, and papilla preservation techniques’ outcomes (C) to improve PD, CAL, GR, and periodontal stability (O)?” An online search was conducted on PubMed, Cochrane Library, and Embase. Only randomized …

Is The Facial Bone Wall Critical To Achieving Esthetic Outcomes In Immediate Implant Placement With Immediate Restoration? A Systematic Review, Sergio Charifker Ribeiro Martins, Marcio Da Costa Marques, Michael Gomes Vidal, Pedro Henrique Moreira Paulo Tolentino, Roberto Galvão Dinelli, Gustavo Fernandes, Jamil Awad Shibli

MOSDOH Faculty Publications

Background. Rehabilitation in the anterior region requires specific conditions for success, such as the presence of papilla, emergence profile, and balance between pink and white esthetic. Objectives. This systematic review aimed to evaluate the esthetic risk associated with immediate implant placement with immediate restoration in the anterior superior area, where the facial bone plate may be absent or deficient. Materials and methods. The search was done in PubMed, Embase, Cochrane, Lilacs, Scopus, Scielo, and Google Scholar databases. The investigation involved clinical studies and observational studies published between January 2012 and July 2023. Studies were excluded if there was less than …

Critical-Size Defects Reconstruction With Four Different Bone Grafts Associated With E-Ptfe Membrane: A Histomorphometric Experimental In Vivo Study, Gustavo Fernandes, Filipe Castro, Rafael Martins Pereira, Wendel Teixeira, Sergio Gehrke, Julio Cesar Joly, Juan Blanco Carrion, Juliana Campos Hasse Fernandes

MOSDOH Faculty Publications

Objectives: The goal of this study was to assess the newly formed bone and the remnant biomaterial by comparing four different bone grafts used to treat critical-size defects, associated or not with the non-resorbable membrane.

Materials and methods: Two calvaria critical-size bone defects were created in 50 male Wistar rats. They were divided into blood (G1), autogenous (G2), bioglass (G3), hydroxyapatite (G4), and xenograft (G5) groups, associated or not with e-PTFE. The experimental periods were 15 and 45 days. Sections were prepared for histomorphometric assessment. All data were analyzed by the mixed-effects model with multiple comparisons (significance level, p < .05).

Results: …

Protein Expression Of Bone Marrow Mesenchymal Stem Cells Transfected On Green Fluorescent Protein Mrna And Collagen-Coated Titanium Disk, Wasamon Swangvong

Chulalongkorn University Theses and Dissertations (Chula ETD)

New strategies for surface modification have been explored to promote osseointegration and osteogenesis, which are crucial factors for the success of titanium dental implants. Coating the titanium surface with mRNA encoding therapeutic growth factors may achieve these objectives. In our pilot study, we employed green fluorescent protein (GFP) mRNA as a model. Our investigation focused on determining whether titanium disks coated with GFP mRNA encapsulated with lipid nanoparticles and collagen Type I (GFP mRNA-Col) could enhance transfection in human bone marrow mesenchymal stem cells (hBMSCs), in comparison to titanium disks coated with GFP mRNA alone, without collagen. We tested various …

Influence Of Scaling And Root Planing With Minocycline Microspheres On Clinical Outcomes Of Patients With Periodontitis, Nupoor Sandeep Kulkarni

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Scaling and root planning (SRP) has been established as a “gold-standard” non-surgical initial treatment for periodontitis. Along with SRP, some systemic adjuncts like systemic antibiotics were used in the past to gain maximum benefits of SRP by reducing the need for further periodontal surgeries. Due to some drawbacks of systemic antibiotic use, like “transient antibiotic resistance”, “non-adherence” and “insufficient concentrations in the periodontal pockets to be clinically effective”, there was a shift towards the use of local antibiotic adjuncts to SRP like minocycline, tetracycline, chlorhexidine etc. Minocycline is a semi-synthetic tetracycline derivative which is available in a powder form, …

Periodontal Regeneration Related To Periodontitis Treated By Garden Cress And Ozone Therapy. (Randomized Clinical &Experimental Study), Zienab S. Farid, Doaa Adel Habba, Gihan Adel Balbola, Noura Mohammed Bakr

Journal of Medicine in Scientific Research

Objective: In this article, garden cress and ozone were evaluated for their potential therapeutic properties of PDL and resorption of alveolar bone in the periodontal tissues based on rats' experimental periodontitis and to assess the clinical effectiveness of local application of garden cress and ozone for treatment and management of periodontitis patients using scaling and root planing. Methodology: Thirty mature Wistar male albino rats. Three groups of rats were formed; periodontitis without treatment, periodontitis with garden cress, and periodontitis plus ozone therapy. The present study also included thirty periodontitis Patients were randomly allocated to one of three groups of ten …

Digital Assessment Of Soft And Hard Tissue Alterations After Anterior Maxillary Tooth Extraction, Robin Jalkh, Stephanie Mrad, Emile Chrabieh, Joe Bassil

International Arab Journal of Dentistry

Objectives: This study aimed to assess dimensional alterations in soft and hard tissues 12 weeks post-extraction using novel computerized methods. Secondary objectives included exploring potential correlations between soft tissue changes and underlying bone variations, as well as investigating relationships between soft and hard tissue alterations and various contributing factors.

Methods: For all patients, preoperative and postoperative CBCT scans and intra-oral scans were obtained. Soft and hard tissue dimensions before extraction and at 12 weeks post-extraction were measured using 3D-slicer software. Both DICOM and STL files were superimposed, and measurements were taken at 2mm and 4mm from the facial …

Bone-To-Implant Surface Contact As A Criterion For Immediate Implant Placement With Simultaneous Sinus Augmentation In The Upper Molars' Interradicular Bone: A Radiological Cbct Study, Nawal Baba, Nabil Ghosn, Abdel Rahman Kassir, Lara Nasr, Gabriel Menassa, Carole Chakar

International Arab Journal of Dentistry

Objectives: The aim of this study is to determine which type of vertical relationship (between molar apices and the sinus floor) is correlated with the most favorable bone to implant contact (BIC).

Methods: The CBCT database of the Faculty of Dental Medicine was used for datasets. For each dataset, a prosthetically-driven virtual implant placement was placed in the remaining interradicular bone. Potential BIC was measured using two different implant macrogeometries (straight and tapered).

Results: The study included 20 maxillary molars with divergent root anatomy: 90% of the molars had a type II vertical relationship with the sinus …