Pediatric Dentistry and Pedodontics Commons^™

Physico-Mechanical Properties And Streptococcus Mutans Biofilm Formation Of Bio‑Based Flexible Crowns Versus Stainless Steel And Zirconia Crowns For Pediatric Full-Coverage Restorations, Tzu-Yu Peng, Szu-Yu Lai, Yan-An Wu, Ya-Ting Yang, Yuichi Mine, Huei-Yu Huang

Journal of Dental Sciences

Background/purpose: Bio‑based flexible (BFX) have recently emerged as a potential alternative to conventional pediatric full‑coverage restorations, but evidence regarding their properties and microbial behavior remains limited. Thus, this study aimed to evaluate the physico-mechanical properties and microbial behavior of BFX crown compared with stainless steel crowns (SSC) and zirconia crowns (ZRC) for pediatric full-coverage restorations.

Materials and methods: Mandibular primary molar crowns from BFX, SSC, and ZRC were assessed. Weight was measured using an electronic balance, and surface roughness and topography were evaluated using a stylus profilometer and atomic force microscopy. The arithmetic mean roughness (Ra) and root mean square …

Delayed Tooth Eruption As An Early Clinical Indicator Of Genetical Tooth Agenesis: A Family-Based Study Of Cases With Whole-Exome Sequencing, Yu-Chen Jeng, I-Ting Chen, Hui-Ching Cheng, Hsin-Yu Huang, Chao-Kai Hsu, Yu-Fen Yen

Journal of Dental Sciences

Delayed tooth eruption is frequently considered a benign developmental variation but may represent an early sign of genetically driven tooth agenesis. We evaluated a 22-month-old female presenting with markedly delayed eruption (only eight primary teeth) and a positive family history of ectodermal features. Given the inconclusive early radiographic findings, whole-exome sequencing (WES) was utilized. WES revealed the proband carried a heterozygous EDARADD variant (NM_080738:c.328G>T; p.Asp110Tyr). Subsequent familial segregation analysis identified an additional heterozygous WNT10A variant (NM_025216:c.637G>A; p.Gly213Ser) within the broader family. The EDARADD variant alone was associated with varying presentations from normal dentition to delayed eruption. Furthermore, the …