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The Effects Of Mechanical Vibration On Human Chondrocytes In Vitro, Bradley J. Gauthier

Master's Theses (2009 -)

Introduction: Inflammation is the biological basis of temporomandibular joint disorders (TMD), when severe it can lead to osteoarthritis. One of the physical therapies used to manage this condition is mechanical vibration, as has been used in medicine for many years as a non-pharmacological therapy. Recently an FDA approved dental device called AcceleDent has been introduced to increase the rate of tooth movement and decrease pain. As the device-generated vibration transmits to the TMJ, it is important for us to investigate whether mechanical vibration influences TMJ on its biologic basis – chondrocytes under normal and inflammatory conditions. Materials and Methods: Human …