Oral Biology and Oral Pathology Commons^™

The Dental Safety Net In Montgomery County: A Status Report, Sequoia Y. Butcher

Master of Public Health Program Student Publications

Background: Adult oral health has been identified as a major public health problem by the United States Surgeon General. A substantial number of adults between the ages of 20 and 64 have untreated tooth decay. There are limited treatment options for adults without dental insurance. Low-income adults must turn to free/low cost clinics, or private dentists that accept Medicaid to receive dental care. However, these resources are often limited. When the resources are not available these adults are left to deal with untreated tooth decay which can lead to worsening conditions and other health issues.

Methods: Eleven key-informant interviews were …

Etiology Of Noncarious Cervical Lesions, Caren M. Barnes

College of Dentistry: Faculty Publications

As the number of older adults in the United States continues to grow, this change in patient demographics will profoundly affect the practice of dental hygiene. Not only are there more older adults, but they are also retaining more of their natural teeth than ever before. The risk of alveolar bone loss; gingival recession, which can lead to exposed cervical and root areas of the teeth; and tooth wear all increase with age. The confluence of these factors raises the risk of noncarious cervical lesions (NCCLs).

The prevalence of NCCLs is growing, largely due to the rising numbers of older …

Analysis Of Periapical Biopsies Submitted For Histopathological Evaluation: A Retrospective Study, Abdullah I. Alqaied

Master's Theses

Apical periodontitis is the most common pathological process in the periapical region. Disciplined clinical and radiographic evaluations and appropriate diagnostic tests can detect lesions related to apical periodontitis. Aside from this, lesions mimicking pulp-related pathology but unrelated to pulpal infection and necrosis are occasionally discovered in the periapical region. The objective of this study was two-fold: (1) to determine the prevalence of diverse periapically located pathological entities, and (2) to apply that information to evaluate the rationale for routine submission of surgically obtained tissue for histological examination and diagnosis. Methods: A 5-year retrospective analysis of pathology reports from the UCONN …

Composition Of The Adult Digestive Tract Bacterial Microbiome Based On Seven Mouth Surfaces, Tonsils, Throat And Stool Samples, Nicola Segata, Susan Kinder Haake, Peter Mannon, Katherine P. Lemon, Levi Waldron, Dirk Gevers, Curtis Huttenhower, Jacques Izard

Department of Food Science and Technology: Faculty Publications

Background: To understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. The digestive tract includes diverse habitats and hosts the human body’s greatest bacterial density. We describe the bacterial community composition of ten digestive tract sites from more than 200 normal adults enrolled in the Human Microbiome Project, and metagenomically determined metabolic potentials of four representative sites.

Results: The microbiota of these diverse habitats formed four groups based on similar community compositions: buccal mucosa, keratinized gingiva, hard palate; saliva, tongue, tonsils, throat; sub- and supra-gingival plaques; …

Racemization Of Amino Acids In Teeth For The Determination Of Age, Andrea Lee Toll

Masters Theses & Specialist Projects

Instrumental to forensic investigations is the ability to identify unknown human remains providing key evidence to criminal cases, resolution to missing persons, and assistance in mass or natural disasters. Identification of remains in an effort to determine age is an area of forensics that has received considerable attention. Traditional methods in age determination such as morphology are often biased, antiquated, and frequently result in a large margin of error. Conversely, the emergence of new forensic techniques provide promise to reduce the margin of error in determining age. One such technique has focused on relating the extent of amino acid racemization …

The Effect Of Extracorporeal Shock Wave (Esw) On Cementoblasts In Vitro, Joshua Barta

Master's Theses (2009 -)

Root resorption is an adverse consequence of orthodontic treatment, and currently no effective treatment method exists. Extracorporeal shock wave (ESW) has been applied to enhance angiogenesis, growth and healing of bone, but the effects of ESW on root resorption have not been studied. Cementoblasts are the cells responsible for forming and repairing cementum covering the dental root, and ESW may enhance this reparative process. The purpose of this study was to investigate the effects of ESW on cementoblasts to determine if ESW could potentially be used to treat root resorption. OCCM.30 cementoblasts were prepared in suspension at a density of …

Pathogenicity Of Treponema Denticola Wild-Type And Mutant Strain Tested By An Active Mode Of Periodontal Infection Using Microinjection, Jacques Izard, Hajime Sasaki, Ralph Kent

Department of Food Science and Technology: Faculty Publications

The available passive mode of periodontal infections in mice requires high efficiency of bacterial attachment and invasiveness and is not always suitable to test the pathogenicity of genetically engineered mutant strains. We developed an active mode of oral infection, using microinjection in the marginal gingiva of mice, to test the pathogenicity of a genetically engineered Treponema denticola mutant strain deficient in intermediate-like filaments, compared to the wild-type strain. This targeted mode of infection inoculates the bacterial strain to be tested directly at a lesion site (needle entry point) located at the future periodontal lesion site. The efficiency of T. …