Oral Biology and Oral Pathology Commons^™

Resorbable Barrier Effect In Sinus Graft Using Anorganic Bone, Kyung-Soo Choi

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of a resorbable membrane on new bone formation in human maxillary sinus augmentation using anorganic bovine material is unclear at the present time. As a pilot study, six patients who required bilateral maxillary sinus augmentations for endoessous dental implant treatment were grafted with anorganic bovine bone material. All six patients had a resorbable collagen membrane placed over the graft material on only one side for the sinus augmentation. At the time of implant placement, a minimum of 8 months following sinus graft healing, a biopsy was made of each side to permit histomorphometric analysis.

Similar amounts of new …

Detection Of The Argonaute Protein Ago2 And Micrornas In The Rna Induced Silencing Complex (Risc) Using A Monoclonal Antibody, K. Ikeda, M. Satoh, Kaleb M. Pauley, M. J. Fritzler, W. H. Reeves, E. K. Chan

Science and Mathematics Faculty Publications

MicroRNAs (miRNAs) are short RNA molecules responsible for post-transcriptional gene silencing by the degradation or translational inhibition of their target messenger RNAs (mRNAs). This process of gene silencing, known as RNA interference (RNAi), is mediated by highly conserved Argonaute (Ago) proteins which are the key components of the RNA induced silencing complex (RISC). In humans, Ago2 is responsible for the endonuclease cleavage of targeted mRNA and it interacts with the mRNAbinding protein GW182, which is a marker for cytoplasmic foci referred to as GW bodies (GWBs). We demonstrated that the antiAgo2 monoclonal antibody 4F9 recognized GWBs in a cell cycle …

Histopathologic Findings And Assessment Of Cervical Lymph Node Metastasis In Oral Squamous Cell Carcinoma Of Malaysian Patients, Ismail S. B., Rosnah Binti Zain, Kipli N. P., Abraham T., Ismail M. S., Rahman Z. A. A., Prepageran N., Jalaludin M. A. B.

Prof. Dr. Rosnah Binti Zain

Purpose: To evaluate some histopathologic parameters and relate with the occurrence of cervical lymph node metastasis in oral squamous cell carcinoma (OSCC) in Malaysian patients. Methods: A total of 44 cases of OSCC resected were included. The resected specimens were examined for the OSCC type, degree of differentiation, pattern of invasion (at the tumour invasive front), greatest dimension and the depth of stromal invasion. Where there is no neck resection, the clinical nodal status was obtained from the Oral Cancer database maintained at the University of Malaya Oral Cancer Research and Coordinating Centre (UM-OCRCC) while the histopathologic data were obtained …

Immunoexpression Of Prb And Egfr Using Tissue Microarray (Tma) Technique - A Preliminary Study, Kipli N. P., Cheong C. S., Rosnah Binti Zain, Hamid S., Lim K. P., Abraham T., Ismail M. S., Hussaini H. M.

Prof. Dr. Rosnah Binti Zain

Purpose: To assess the expression of pRb and EGFR in oral epithelial lesions using TMA technique. Methods: Paraffin embedded specimens were selected from the archives of the Diagnostic Laboratories at the Faculty of Dentistry, University of Malaya and Universiti Kebangsaan Malaysia. Selected epithelial areas were cored and developed into tissue microarray blocks. A total of 32 samples for pRb and 50 samples for EGFR were analysed using immunohistochemical techniques. Results: Abnormal pRb staining (1+ or less) was seen in 80% (8/10) OSCC, 38.5% (5/13) dysplastic and 22.2% (2/9) normal/hyperplastic epithelium. Positive EGFR staining was observed in 25/35 (71.4%) OSCC cases …

Expression Of Human B-Defensin-3 In Oral Squamous Cell Carcinoma Using Tissue Microarray - A Preliminary Study, Hussaini H. M., Lim P. K., Rahman R. A., Abraham T., Cheong C. S., Rosnah Binti Zain, Ismail M. S., Nam A. N.

Prof. Dr. Rosnah Binti Zain

Purpose: Human b-Defensin (hBDs) is an epithelial origin, cationic antimicrobial peptides. Their expression is reported in oral mucosa, gingiva and salivary glands. However, their protective role is not well understood. It has been suggested that bacterial and viral infection are an important factors in the process of carcinogenesis. This study investigated the expression of hBD-3 in oral squamous cells carcinoma (OSCC). Methods: 29 OSCC and 23 samples of normal and dysplastic tissues were obtained from Oral Pathology diagnostic laboratory, faculty of Dentistry, UKM and UM. The tissues were arrayed and the expression of hBD-3 was analysed using immunohistochemistry technique. Results: …

Immunoexpression Of Prb And Egfr Using Tissue Microarray (Tma) Technique - A Preliminary Study, Kipli N. P., Cheong C. S., Rosnah Binti Zain, Hamid S., Lim K. P., Abraham T., Ismail M. S., Hussaini H. M.

Prof. Dr. Rosnah Binti Zain

Purpose: To assess the expression of pRb and EGFR in oral epithelial lesions using TMA technique. Methods: Paraffin embedded specimens were selected from the archives of the Diagnostic Laboratories at the Faculty of Dentistry, University of Malaya and Universiti Kebangsaan Malaysia. Selected epithelial areas were cored and developed into tissue microarray blocks. A total of 32 samples for pRb and 50 samples for EGFR were analysed using immunohistochemical techniques. Results: Abnormal pRb staining (1+ or less) was seen in 80% (8/10) OSCC, 38.5% (5/13) dysplastic and 22.2% (2/9) normal/hyperplastic epithelium. Positive EGFR staining was observed in 25/35 (71.4%) OSCC cases …

Effect Of Mouthrinses On Surface Microhardness Of Selected Dental Composites, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Objective: To compare the surface microhardness of composites(Spectrum®TPH, Filtek™Z350, Ceram•X mono and Ceram•X duo-enamel shade) before and after immersion in alcohol containing mouthrinses (Listerine), alcohol-free mouthrinses (Oral-B) and experimental herbal mouthrinses based on plant extract (mouthrinses X, Y and Z). Methods: 60 disc-shaped specimens of approximately 10mm x 2mm were perpared from various composites using perspex split mould and was cured for 40 seconds. The irradiated surface was polished using Sof-Lex pop-on polishing discs. The specimens were randomly divided to 6 groups. Microhardness was recorded before immersion (control group) using a load of 200g for 15 seconds using Vickers microhardness …

Shear Bond Strength Of Orthodontic Adhesives On Different Tooth Types: An In Vitro Study, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Introduction: Owing to the variety of materials and methods employed, comparison of the results and findings from bonding studies is difficult. Until recently, several types of teeth have been used in published research papers as a substrate in orthodontic bonding research including bovine incisors, fresh and rebonded human premolars. Objectives: The purpose of this study was to compare the shear bond strength of an adhesive bonded to different tooth surfaces (human premolar, bovine incisor and rebonded human premolar). Methods: Two groups of thirty premolar teeth and one group of bovine incisors had brackets attached in a standardized manner using Transbond …

Multiple Intelligences And Academic Performance Among Malaysian Undergraduate Dental Students, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Objectives: To identify the nature of multiple intelligences among dental students and investigate the relationship between these intelligences and performance in the various skill areas of dentistry. Methods: Sixty-one final year dental students at the Faculty of Dentistry, University of Malaya in Malaysia were administered a Multiple Intelligence Inventory [(MII), David Larear, 1991)] after their final written examinations. MII comprised 80 4-point likert items assessing eight types of multiple intelligences: Verbal/Linguistic, Visual Spatial, Logical Mathematical, Musical Rhythmic, Intra Personal, Body Kinesthetic, Inter Personal and Naturalist. These intelligences were correlated with six academic performance scores: Amalgam Class II, Composite, Crown & …

Investigating Examiner Consistency In Criterion-Based Assessment Using Rasch Measurement, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

In the implementation of criterion-based assessment some disparities in the interpretation of the assessment criteria have been observed.Therefore it is essential that a standardization exercise be carried out to ensure equitable and fair assessment. Objectives: The purpose of the study was to evaluate inter-examiner variability and examiners' internal consistency in applying a criterion-based assessment. Method: The subjects consisted of 9 full-time staff of the Department of Conservative Dentistry, University of Malaya, 4 part-time staff and 2 postgraduate students. One buccally-approached and one palatally-approached Class III cavity preparation were assessed according to a set of criteria developed by the department. Both …

Oral Cancer Prevalence In Virginia, Karin C. Loftin, Michele Darby, Stacey Plichta, Sophie Thompson, Shreeram Kumar, Louis Abbey

Dental Hygiene Faculty Publications

Purpose. Oral and pharyngeal cancer affects 30,000 Americans a year and kills one fourth of those diagnosed. The primary risk factors for oral cancer are past or present cigarette and tobacco usage, and alcohol consumption in conjunction with tobacco use. Even though the prevalence of oral cancer is relatively low in the younger age groups, this group is most likely to benefit from intervention programs designed to change risky behavior such as smoking, and to prevent oral cancer in the later years. The goal of the study was to identify high-risk target areas for an oral cancer prevention program in …