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Oral Biology and Oral Pathology Commons

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Full-Text Articles in Oral Biology and Oral Pathology

Influence Of The Oral Microbiome On General Health, Zvi G. Loewy, Shoshana Galbut, Ephraim Loewy, David A. Felton Jan 2018

Influence Of The Oral Microbiome On General Health, Zvi G. Loewy, Shoshana Galbut, Ephraim Loewy, David A. Felton

Touro College of Pharmacy (New York) Publications and Research

The prevalence of edentulism is common worldwide. While improvements in access to healthcare and dental care are reducing the prevalence rate of edentulism, the rapidly growing number of elderly as a percent of the global population will sustain a need for denture therapy for the foreseeable future. While denture use has positive impacts on the quality of life, their use is associated with some problems and risks. Denture stomatitis, a chronic infection-related inflammatory disorder of the oral mucosa, is extremely common and has been reported to occur in up to two-thirds of denture wearers. Importantly, epidemiology studies have shown edentulism …


Oral Biofilms: Development, Control, And Analysis, Daniela Berger, Aviva Rakhamimova, Andrew Pollack, Zvi G. Loewy Jan 2018

Oral Biofilms: Development, Control, And Analysis, Daniela Berger, Aviva Rakhamimova, Andrew Pollack, Zvi G. Loewy

Touro College of Pharmacy (New York) Publications and Research

The oral cavity harbors hundreds of microbial species that are present either as planktonic cells or incorporated into biofilms. The majority of the oral microbes are commensal organisms. Those that are pathogenic microbes can result in oral infections, and at times can initiate systemic diseases. Biofilms that contain pathogens are challenging to control. Many conventional antimicrobials have proven to be ineffective. Recent advances in science and technology are providing new approaches for pathogen control and containment and methods to characterize biofilms. This perspective provides (1) a general understanding of biofilm development; (2) a description of emerging chemical and biological methods …


Oral Health: The Need For Both Conventional Microbial And Molecular Characterization, Elisheva Friedman, Negin Alizadeh, Zvi G. Loewy Jan 2017

Oral Health: The Need For Both Conventional Microbial And Molecular Characterization, Elisheva Friedman, Negin Alizadeh, Zvi G. Loewy

Touro College of Pharmacy (New York) Publications and Research

This study aims to consider the microbial distribution in oral disease, as well as gene analysis and expression, in elucidating: 1, the fundamental underpinnings of oral disease, and 2, the potential relationship between oral diseases and systemic health. A key focus is identifying the microbiota associated with oral disease manifestations characterized by both conventional microbiological and molecular methods. Variations in the observed microbial populations characterized by conventional and molecular approaches have been identified for caries, periodontitis, peri-implantitis, and stomatitis. The discovery of therapeutic approaches for oral disease will require comprehensive microbial and genomic analysis. This study evaluated the current state …