Oral Biology and Oral Pathology Commons^™

Salivary Mmp-9 In The Detection Of Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Mina D. Fahmy, Arndt Guentsch, Korosh Roshanghias, Joschka Hennings, Stefan Schultze-Mosgau

School of Dentistry Faculty Research and Publications

Background: Oral squamous cell carcinoma (OSCC) is the most common malignant tumour of the oral cavity. Detection of OSCC is currently based on clinical oral examination combined with histopathological evaluation of a biopsy sample. Direct contact between saliva and the oral cancer makes measurement of salivary metalloproteinase- 9 (MMP-9) an attractive alternative.

Material and Methods: In total, 30 OSCC patients and 30 healthy controls were included in this prospective study. Saliva samples from both groups were collected, centrifuged and supernatant fluid was subjected to ELISA for assessment of MMP-9. The median salivary MMP-9 values with interquartile range (IQR) of OSCC …

Longterm Quality Of Life After Oncologic Surgery And Microvascular Free Flap Reconstruction In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Korosh Roshanghias, Francy Eichmann, Stefan Schultze-Mosgau

School of Dentistry Faculty Research and Publications

Background: Quality of life (QoL) has become increasingly important in cancer treatment. It refers to the patient’s perception of the effects of the disease and therapy, and their impact on daily functioning and general feeling of well being. Material and Methods: In this prospective study, a total of 100 patients treated at our institution, completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and the specific EORTC QLQ-H&N35 module. The questionnaires were distributed to the patients between 12 and 60 months postoperatively. Results: Global QoL score was 58.3 and mean score for functioning scale was 76.7. …

The Effect Of Extracorporeal Shock Wave (Esw) On Cementoblasts In Vitro, Joshua Barta

Master's Theses (2009 -)

Root resorption is an adverse consequence of orthodontic treatment, and currently no effective treatment method exists. Extracorporeal shock wave (ESW) has been applied to enhance angiogenesis, growth and healing of bone, but the effects of ESW on root resorption have not been studied. Cementoblasts are the cells responsible for forming and repairing cementum covering the dental root, and ESW may enhance this reparative process. The purpose of this study was to investigate the effects of ESW on cementoblasts to determine if ESW could potentially be used to treat root resorption. OCCM.30 cementoblasts were prepared in suspension at a density of …