Endodontics and Endodontology Commons^™

Effect Of Beverages With Varying Acidity On The Surface Microhardness Of Resin Composites: An In Vitro Study, Vishnu S, Shweta Purohit, Yashas Dm, Mangala G K, Chinnu Mary Jose, Athira Bs

International Arab Journal of Dentistry

Introductions: The increasing consumption of acidic beverages has raised concerns regarding their impact on the longevity of composite resin restorations. Surface microhardness is a critical parameter for evaluating the mechanical performance and durability of restorative materials.

Aim: To evaluate and compare the effect of beverages with varying acidity on the surface microhardness of different composite resin materials and to assess the relationship between beverage pH and microhardness reduction.

Materials and Methods: This in vitro experimental study included 140 disc-shaped specimens of four composite resins: Filtek Z350 XT, Tetric N-Ceram, Beautifil II, and Charisma Smart (n = 35 …

Prevalence Of Acute Periapical Abscesses In Cannabis Users, Ilan Rotstein D.D.S., Joseph Katz D.M.D.

The New York State Dental Journal

Background: Cannabis use and cannabis-related disorders have increased significantly worldwide. The aim of this study was to assess the prevalence of acute periapical abscesses (PAs) in cannabis users.

Methods: Data from 1,799,122 patients were analyzed and the odd ratio (OR) of acute PAs and their association with cannabis use were statistically compared.

Results: Patients using cannabis showed significantly more PAs than nonusers. The difference was statistically significant. Following adjustment for diabetes and smoking comorbidities, the statistical difference remained significant.

Conclusion: The risk for acute PAs is significantly higher in cannabis users as compared to nonusers.

Clinical Outcomes Of Adjunctive Use Of Oxygen-Releasing Formula In Non-Surgical Treatment Of Periodontal Abscess Associated With Type 2 Diabetes Mellitus, Anil Kumar Kanakamedala, Laxmi Kavya Gangireddy, Gautami S Penmetsa, Sruthima Gottumukkala, Mohan Kumar Pasupuleti, Konathala Santhosh Venkata Ramesh

Journal of Dentistry Indonesia

Background: This study aimed to evaluate the effectiveness of oxygen-releasing formula (ORF) as an adjunct in the non-surgical management of periodontal abscess in patients with type 2 diabetes mellitus.

Methods: This split-mouth clinical trial was conducted on 14 patients with periodontal abscess with type 2 diabetes mellitus (T2DM), who were divided into a control group, nonsurgical periodontal therapy (NSPT) alone, and a test group (NSPT+ORF). Parameters such as Landry's healing index (HI) were evaluated at 1 week, 2 weeks, and 1 month. Probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing presence or absence (BOP) …

Psychosocial And Functional Impact Of Temporomandibular Disorder Subtypes Among Adults: A Cross-Sectional Study In Indonesia, Ni Luh Dewi, Wita Anggraini, Maria Valiente-Lopez, Carolina Marpaung

Journal of Dentistry Indonesia

Background: Temporomandibular disorders (TMDs) affect psychological, functional, and pain-related aspects of oral health-related quality of life (OHRQoL). However, the differential impact of pain-related and non-pain-related TMDs remains limited. This study aimed to evaluate the impact of different TMD subtypes on psychological distress, jaw function, and OHRQoL in young adults and to determine whether pain-related TMDs exert a greater effect than non-pain-related TMDs.

Methods: In this cross-sectional study, 278 university students (aged 18–24 years) were categorized into no TMD (NT), pain-related TMD (PT), intra-articular TMD (IT), and combined TMD (CT). Diagnoses were made using the 5Ts Questionnaire screening tool …

Adverse Drug Reaction Reporting In Dental Practice And The Importance Of Pharmacovigilance In Dental Education, Radhakrishna Lagishetty, Lakshmi Ramya T, Kvr Barath Raju, Mohan Kumar Pasupuleti

Journal of Dentistry Indonesia

Background: Adverse drug reactions (ADRs) are a critical component of patient safety; however, ADR monitoring remains underutilized in dentistry. This study aimed to assess knowledge, attitudes, and practices regarding ADR reporting among undergraduate and postgraduate students and practicing dentists.

Methods: A cross-sectional observational study was conducted using a structured, validated 19-item questionnaire covering socio-demographics, knowledge (6 items), attitude (4 items), and practice (5 items), which was distributed both in person and online. A total of 258 complete responses were analyzed out of 300 individuals contacted (response rate: 86%). Descriptive statistics and Chi-square tests were applied, with p < 0.05 considered statistically significant.

Results …

Investigation Of Patients' Use Of Non-Pharmacological Substances In Dental Pain Management, Neslihan Yılmaz Çırakoğlu, Özgenur Kaya

Journal of Dentistry Indonesia

Background: Dental pain is a complex condition influenced by biological, biochemical, environmental, and psychological factors. Before seeking professional care, many patients attempt to relieve dental pain using self-administered, non-medical agents. This study aimed to investigate patients’ use of non-pharmacological substances in dental pain management and to identify factors influencing these practices.

Methods: The questionnaire consisted of four sections addressing demographic characteristics, oral hygiene habits, pain characteristics, and pain-relief agents. Categorical variables were analyzed using Pearson’s chi-square test. Categorical data are presented as frequencies and percentages, while continuous data are expressed as mean ± standard deviation and median values. …

Orthodontic Camouflage Treatment Of A Severe Class Iii Skeletal Pattern With Anterior Open Bite: A Case Report, Dikeledi Maureen Letsholo, Mandla Dominic Nyakale, Mosimane Peter Silas Sethusa

Journal of Dentistry Indonesia

Background: Class III malocclusion combined with anterior open bite (AOB) is one of the most challenging occlusal problems to treat. The objective of this article was to report a case of an adult female patient diagnosed with Class III malocclusion combined with an anterior open bite and a hyperdivergent facial pattern.

Case Report: Camouflage orthodontic treatment with the extraction of maxillary and mandibular first premolars was used to treat the patient. Anterior teeth were retracted maximally against the Nance holding arch and fixed lingual arch appliances, and box elastics were used to close AOB. At the end of …

Hypo-Responsiveness Of The Dental Pulp In Patients With Type 2 Diabetes And Hypertension: A Cross-Sectional Study, Kavitha M, Mallolu Anthony Sanjana Vijay, Niveditha B, Fathima A.I, Pavithra D, Vigneshwaran J

International Arab Journal of Dentistry

Introduction: Diabetes mellitus and hypertension, two of the most prevalent metabolic disorders worldwide, exert profound and progressive effects on multiple physiological systems. While their systemic complications are well documented, their subtle yet clinically significant impact on oral structures, particularly the dental pulp, remains underexplored.

Objectives: This study aims to assess the functional responsiveness of dental pulp nerves in individuals with type 2 diabetes mellitus and systemic hypertension, and to compare the findings with responses from healthy individuals, using an Electric pulp tester (EPT) as a diagnostic tool.

Methods: A total of 600 teeth from 75 adult patients (25 diabetic, 25 …

Can Gingival Crevicular Fluid Help In Diagnosing Pulp Inflammation? A Systematic Review, Wael Kassamany, Roula Abiad

BAU Journal - Science and Technology

This review aims to find if there’s a positive correlation between biological markers detected in human gingival crevicular fluid and pulp inflammation.

An electronic search of three databases; PubMed, EBSCOhost and Google Scholar was conducted using the keywords “tooth or teeth or pulp” AND “gingival crevice fluid or gingival crevicular fluid” for English articles published between the year 1990 and 2026. Information regarding study design, patients age range and gender distribution, sampling method used, types of biomarkers studied, assay test used, and key findings of each article were extracted and analyzed.

Biomarkers studied were substance P “SP”, neurokinin A “NKA”, …

Time And Dose Dependent Effects Of Adipose-Derived Stromal Vascular Fraction Exosomes On Human Dental Pulp Stem Cell Proliferation, Sylva Dinie Alinda, Anggraini Margono, Indah Julianto, Dini Asrianti Bagio

Journal of Dentistry Indonesia

Background: Cell proliferation is essential for tissue repair and immunomodulation in regenerative dentistry. Adipose-derived stromal vascular fraction (AD-SVF) is a promising autologous source for tissue engineering. Its exosomes (AD-SVF Exo), as cell-free products stable under ischemic conditions, represent an ethical and attractive modality for dental tissue regeneration and broader regenerative applications. Prior study indicates that AD-SVF Exo can enhance human dental pulp stem cell (hDPSC) migration and proliferation, particularly at low concentrations, but their detailed time- and dose-dependent proliferative effects remain unclear. This study aimed to investigate the time- and dose-dependent effects of low-concentration AD-SVF Exo on hDPSC proliferation …

In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami

Journal of Dentistry Indonesia

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach.

Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond …

Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu

Journal of Dentistry Indonesia

Background: This study aimed to evaluate canal transportation, centering ability, structure model index (SMI), surface area, and root canal volume changes in the mesial canals of mandibular first molars using micro-CT.

Methods: Twenty-four mandibular first molars with two separate mesial canals and moderate curvature were included. Teeth were scanned using micro-CT before instrumentation and randomly divided into three groups (N = 8). Root canals were prepared using OneShape, OneCurve, and Rotate file systems, followed by post-instrumentation micro-CT scanning (10µm/pixel resolution). Changes in canal volume, surface area, transportation, centering ability, and SMI were analyzed at the apical, middle, and …

Retrospective Cbct Evaluation Of Missed Root Canals And Their Association With Periapical Lesions In A Makkah-Based Population, Mashael Alqahtani, Samia Mohamed Elsherief, Ibtesam Kamel Afifi

Journal of Dentistry Indonesia

Background: Missed root canals are common and can cause persistent periapical disease, making the assessment of their prevalence essential for improving diagnostic accuracy and treatment outcomes. This study aimed to investigate the prevalence of missed canals and evaluate their association with periapical lesions in root canal–treated teeth in the Makkah population.

Methods: This retrospective cross-sectional study analysed 815 cone-beam computed tomography scans obtained from Umm Al-Qura University between 2019 and 2024. Missed canals and their association with periapical lesions were assessed by two independent observers. Statistical analysis was performed using the chi-square test.

Results: Missed canals were …

Comparative Evaluation Of The Antimicrobial Efficacy Of 2% Chlorhexidine And 10% Dimethyl Sulfoxide At The Resin–Tooth Bond Interface: A Pilot In Vitro Study, Kashmiri Chowdhury, Delphine Priscilla Antony, Praveen Kumar Elango, Amee Sanghavi

International Arab Journal of Dentistry

Objectives: To evaluate and compare the effectiveness of chlorhexidine (CHX) versus dimethyl sulfoxide (DMSO) in preventing Streptococcus mutans adhesion at the resin-tooth bond interface. H0 states no significant difference in antimicrobial efficacy between CHX and DMSO.

Methods: Fifteen extracted molars were randomly assigned to three groups: 2% CHX, 5% DMSO, and saline (control). Surfaces were treated for 60 seconds, bonded with a two-step etch-and-rinse adhesive, and restored with composite resin. Samples were incubated with S. mutans in BHI broth at 37°C for 14 days with broth changes every 48 hours. Confocal laser scanning microscopy (CLSM) assessed microbial viability.

Results: CHX …

Comparative Evaluation Of Irrigants On Sealer Penetration: An In Vitro Confocal Laser Scanning Microscopy Study, Savani Purohit, Priyanka Zinge, Roshan Samuel, Aayush Bhatt, Rucha Pawar

International Arab Journal of Dentistry

Objectives: Effective smear layer removal enhances sealer penetration in endodontics. Chelating agents vary in their efficacy, influencing treatment outcomes. In this study, the depth of penetration of AH Plus and Bio-C root canal sealers into dentinal structures was analysed using confocal laser scanning microscopy (CLSM), following the application of four final irrigants: 17% EDTA, 20% citric acid, 0.2% chitosan, and 5% fulvic acid.

Methods: Ninety-six single-rooted human premolars were prepared and irrigated with sodium hypochlorite. Final irrigation used one of four agents: 17% EDTA, 20% citric acid, 0.2% chitosan, or 5% fulvic acid, followed by sonic activation. Canals were obturated …

Effect Of Root Canal Sealer Type On Obturation Density: An In Vitro Comparison Of Ah Plus, Bioactive Rcs, Novel Bioactive Glass-Based Bioceramic Sealer, And Zinc Oxide Eugenol, Poulomi Guha, Pradeep Solete, Nishitha Arun, Praveen Kumar Elango, Sanyukta Singh

International Arab Journal of Dentistry

Objectives: To compare the obturation density of four root canal sealers—AH Plus, Bioactive RCS, a novel bioactive glass-based bioceramic sealer, and zinc oxide eugenol (ZOE) using a standardized single-cone obturation technique.

Methods: Forty extracted premolars were endodontically prepared to a 15 mm working length and divided into four groups (n=10). Each group was obturated with the same F2-sized guttapercha cones and one of the sealers being evaluated. Weight variations pre-obturation and postobturation, and after complete sealer setting were used to calculate obturation density. Data were analyzed using one-way ANOVA and Tukey’s post hoc test (p < 0.05) to test for group differences.

Results: The bioactive glass-based sealer …

Oral Rehabilitation Of A Pediatric Patient With A Dental Anomaly: A Case Report, Enas Almasri, Mohamed Altinawi, Shadi Azzawi, Imad Katbeh, Anas Abdo

International Arab Journal of Dentistry

Objective: Tooth fusion is an uncommon dental abnormality, occurring in 0.1% of permanent dentition. Fusion of a normal permanent tooth and a supernumerary tooth is unusual. This case report delineates a multidisciplinary strategy for the management of a child with a fused tooth and a concomitant supernumerary tooth. The objective is to progressively illustrate the aesthetic and functional restoration of a smile impacted by a dental fusion abnormality.

Case Report: A 9-year-old boy was referred to the pediatric dental clinic with the chief complaint of a large upper anterior tooth. Intraoral and radiographic investigations showed fusion of the permanent maxillary …

Successful Regenerative Endodontic Therapy Of An Immature Dens Evaginatus Mandibular Second Premolar With Apical Periodontitis Case Report, Jake Horowitz D.D.S., Prashant Sukhani D.M.D., Aaron Brandwein D.D.S., Fagd, Ficd, James Sconzo D.M.D.

The New York State Dental Journal

Background: Dens evaginatus cusps typically have pulpal tissue, and fracturing of the cusp leads to necrosis. Immature permanent teeth with pulp necrosis have traditionally been treated with apexification, which eliminates infection but does not promote root development.

Methods: Regenerative endodontics utilizes revascularization by infiltrating stem cells from the apical papilla and using them to treat an immature necrotic tooth with periapical infection.

Results: Periapical radiolucency completely resolved, root length and thickness increased, and vitality returned at the one-year follow-up.

Conclusion: Regenerative protocols promote root development, reducing fracture risk. This treatment offers improved outcomes with fewer appointments and shorter treatment duration.

J Mich Dent Assoc February 2026

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association delivers news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It remains the main publication reaching Michigan dentists and is available worldwide through ADA Commons.

The February 2026 (Volume 108, No. 2) issue of the Journal is published in a digital format to provide updates and insights for Michigan's oral health community and MDA members. Print editions occur every other month beginning with January.

This issue includes feature articles on Risk Management and 2025 Servant Leadership as well as a clinical reprint …

N Y State Dent J August-September 2026

The New York State Dental Journal

In the August/September 2026 issue, the reader will find the following feature articles:

• Prevalence of Acute Periapical Abscesses in Cannabis Users
• Odontogenic Myxoma in Maxilla
• A Systematic Review of Recommendations for Asynchronous Teledentistry

This issue includes regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Ruptured Silicone Cheek Implant Mimicking Odontogenic Infection: A Diagnostic Pitfall, Kimiko Ohgi, Tomoko Shiraishi, Toyohiro Kagawa, Yasunori Yoshinaga

Journal of Dental Sciences

No abstract provided.

Negative Pulp Sensibility Responses Do Not Necessarily Indicate Pulp Necrosis In Teeth Associated With Cystic Or Cyst-Like Lesions, Le Lu, Xiang Zhang, Ya Shen, He Liu

Journal of Dental Sciences

No abstract provided.

Comparative Evaluation Of The Solubility Of Three Commonly Used Root Canal Sealers When Exposed To Xylene And Endosolv: An In Vitro Study, Aparna Palekar, Piyush Mantri, Basawaraj Biradar, Mukund Singh, Vaidehi Joshi, Pushpal Ingle

International Arab Journal of Dentistry

Objectives: This in vitro study compared the solubility of three root canal sealers, AH Plus (epoxy resin-based), MTA Fillapex (MTA-based), and Cerafill RCS (bioceramic), in two solvents: Xylene and Endosolv.

Methods: Sixty standardized cylindrical specimens were prepared using the three sealers of interest. The specimens were divided into six groups (n = 10) and immersed in either Xylene or Endosolv for 10 minutes. Solubility was assessed by calculating the percentage weight loss before and after immersion. Data were analysed using one-way ANOVA and Tukey’s post hoc test (α= 0.05).

Results: All sealers exhibited statistically significant solubility in both solvents (p …

Musculoskeletal Disorders In Dentistry: An Insight Into Dental Techniques And Practices, Mehwash Kashif, Aman Ashar, Amna Rehman, Abdul Aleem, Sidra-Tul-Muntaha Hashmi, Muhammad Yousuf Ali

Journal of Dentistry Indonesia

Objective: Musculoskeletal disorders (MSDs) are common workplace hazards in dentistry resulting from poor ergonomics and static postures, which lead to back, neck, and upper limb (shoulder, elbow, wrist, and hand) problems among dentists, resulting in harm to their health, productivity, and career. This study aimed to assess the frequency of MSDs, risk factors related to MSDs, and awareness of ergonomics among clinicians. Methods: Data were collected from 400 dental professionals, including house officers, postgraduate trainees, general dentists, and teachers/consultants, each with at least 12 months of practice. Data were collected using a structured, closed-ended questionnaire. Before data collection, ethical approval …

Matrix Metalloproteinase-9 (Mmp-9) Levels In Dentinal Fluid As A Diagnostic Biomarker For Irreversible Pulpitis, Aryo Megantoro, Valeria Widita Wairooy, Ratna Meidyawati, Endang Winiati Bachtiar

Journal of Dentistry Indonesia

Objective: Pulpitis is an inflammatory condition of the dental pulp. The inflammatory status can be accurately assessed by histological examination. Biomarkers, such as matrix metalloproteinases (MMPs), are effective indicators of inflammation severity. Among these, matrix metalloproteinase-9 (MMP-9) has emerged as a key mediator of inflammatory processes associated with pulpitis. However, its clinical application as a biomarker remains limited owing to challenges in its extraction. This study aimed to evaluate the effectiveness of MMP-9 extracted from the dentinal fluid as a biomarker for pulpitis. Methods: Dentinal fluid was collected using the blunt tip of a sterile paper point, following clean …

Articulator Volume 31, Issue 4

Metro Denver Dental Society Articulator Magazine

The 4^th Quarter 2025 of the MDDS Articulator Magazine offers a preview of the 2026 Rocky Mountain Dental Convention, taking place January 22–24 in Denver. The collection spotlights RMDC speakers and the future of dentistry, from the rise of AI and the shift toward integrated whole-health care to the hidden challenges of chronic illness, and a commitment to preserving natural dentition. The articles challenge dental professionals to rethink assumptions, embrace interdisciplinary collaboration and adopt more personalized and evidence-driven approaches to care.

Evaluation Of Anti-Bacterial Efficacy Of Ginger, Resin Gum, And Nigella Sativa Irrigants Against Enterococcus Faecalis: An In Vitro Study, Iman El Ghazzawy, Leen Imad Hasbini, Reem Chamseddine, Wael Betbout, Roula Abiad

International Arab Journal of Dentistry

Objectives: To evaluate the antibacterial efficacy of Ginger, Resin Gum, and Nigella Sativa, against Enterococcus Faecalis.

Methods: Thirty-eight extracted single-rooted premolars were inoculated with E.faecalis, except the negative control, and incubated for 4 weeks. After instrumentation samples were divided into 4 groups (n=7) according to final irrigation: NaOCl+EDTA (Group A), Nigella sativa (B), Resin Gum (C), Ginger (D), plus 2 control groups (n=5): Saline (E), and Saline without bacterial inoculation (F). Cultures were collected at baseline and after irrigation.

Results: One-way ANOVA showed that in groups A-D a statistically significant reduction of bacterial load was observed at …

Comparative Evaluation Of Heat-Treated Retreatment Files On Canal Transportation And Dentin Thickness In Endodontically Treated Teeth: An In Vitro Cbct Study, Monisha Bhate, Pradeep Solete, Aparna Mohan

International Arab Journal of Dentistry

Introduction: Non-surgical retreatment is a conservative approach for managing recurrent endodontic infections requiring efficient removal of obturating material while preserving dentin. Retreatment file systems,through their design and function,plays a vital role in ensuring effective cleaning and minimal structural compromise.

Methods: Forty-five extracted mandibular molars were decoronated and obturated at a standardized root length of 16 mm in both mesial canals. Samples were divided into three groups (n=15): Group 1 – SoliteRS3, Group 2 – Dentsply Protaper Universal Retreatment Files and Group 3 – Neoendo Retreatment Files. Pre- and postoperative CBCT scans were used to assess remaining dentin thickness, …

Cytotoxicity And Osteogenic Potentials Of Mesenchymal Stem Cells Via A Novel Formulation Of Mineral Trioxide Aggregate: An In Vitro Study, Ahmed Elgendi, Ehab Hassanien, Mohamed Nagy, Iman Fathy, Ashraf Abu Seida, Elhassan Hassanein

International Arab Journal of Dentistry

Objectives: Root perforations can lead to periodontitis and alveolar bone loss. This study compared cytotoxicity and osteogenic potential of zirconia-containing mineral trioxide aggregate (MTA) Matreva (MAT group) to MTA Angelus (ANG group) as root perforation repair materials.

Methods: Bone marrow mesenchymal stem cells (BM-MSCs) were extracted from two albino rats and cultivated. The cytotoxicity of the studied materials was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay at three time points: 3, 7, and 14 days. The evaluated materials were employed to guide the osteogenic differentiation of BM-MSCs into osteoblasts. The osteogenic impact was evaluated by assessing calcium …

Cooling Protocols Impact On Nickel-Titanium Rotary Instruments Cyclic Fatigue Resistance Under Extreme Curvatures And Sodium Hypochlorite, Palak Ravjibhai Ranparia, Chintan Joshi, Mona Somani, Aashray Patel, Urooj Desai, Janki Prajapati

Journal of Dentistry Indonesia

Objective: In this work, Hyflex CM, TruNatomy, and Plex V heat-treated nickel titanium rotary instruments were evaluated at body temperature (36 °C ± 1 °C) with and without a cooling protocol to assess the cyclic fatigue resistance. Methods: A 90° curved stainless-steel block was used for cyclic fatigue tests on 60 randomly selected rotary instruments, divided into two groups of 30: body temperature (n = 10) and body temperature with cooling (n = 10). Instruments were further subdivided into 6 groups of 3 different instruments. Cooling protocol group instruments received 5-second spray cooling every 30 seconds, along with continuous 5% …