Open Access. Powered by Scholars. Published by Universities.®

Endodontics and Endodontology Commons™

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Endodontics and Endodontology

Biological Effect Of Modern Bioactive Materials Used In Direct And Indirect Capping; In Vitro Study, Irina Maria Gheorghiu, Alexandru Andrei Iliescu, George Alexandru Denis Popescu, Stana Paunica, Anca Silvia Dumitriu Oct 2024

Biological Effect Of Modern Bioactive Materials Used In Direct And Indirect Capping; In Vitro Study, Irina Maria Gheorghiu, Alexandru Andrei Iliescu, George Alexandru Denis Popescu, Stana Paunica, Anca Silvia Dumitriu

Journal of Mind and Medical Sciences

Objective. In this study, the biological effect of MTA Repair HP (Mineral Trioxide Aggregate Repair High Plasticity) and Biodentine have been tested on a stabilized fibroblast cell line NCTC clone 929. Materials and Methods. We assessed quantitative and qualitative parameters related to cytotoxic effect of the investigated products. The experimental period was 96 hours. Statistical analysis was performed with Kruskal-Wallis and Wilcoxon tests. Results. The detached cells test showed no statistically significant difference on cell culture for Biodentine and MTA Repair HP, while for the cellular density assay we found the same biological effect on the tested fibroblasts in the …


Primary Endodontic Infections - Key Issue In Pathogenesis Of Chronic Apical Periodontitis, Alexandru Andrei Iliescu, Irina Maria Gheorghiu, Sergiu Ciobanu, Ion Roman, Anca Silvia Dumitriu, George Alexandru Denis Popescu, Stana Paunica Oct 2024

Primary Endodontic Infections - Key Issue In Pathogenesis Of Chronic Apical Periodontitis, Alexandru Andrei Iliescu, Irina Maria Gheorghiu, Sergiu Ciobanu, Ion Roman, Anca Silvia Dumitriu, George Alexandru Denis Popescu, Stana Paunica

Journal of Mind and Medical Sciences

Primary root canal infection is a dynamic process. All species of oral microbiota have comparable abilities to establish in the root canals of necrotic teeth. The essential ecological factors in their biological selection are nutrient availability, anaerobic environment and bacterial interactions. In chronic apical periodontitis, all selected microflora residing in the long-term infected habitat of root canals system are synergistic, and each of them can play the role of an endodontic pathogen. Microorganisms living in the root canal system of pulpless teeth progressively reach through anatomical communications to the periodontal ligament where, sooner or later, they cause the inflammatory and …