Dentistry Commons^™

Time And Dose Dependent Effects Of Adipose-Derived Stromal Vascular Fraction Exosomes On Human Dental Pulp Stem Cell Proliferation, Sylva Dinie Alinda, Anggraini Margono, Indah Julianto, Dini Asrianti Bagio

Journal of Dentistry Indonesia

Background: Cell proliferation is essential for tissue repair and immunomodulation in regenerative dentistry. Adipose-derived stromal vascular fraction (AD-SVF) is a promising autologous source for tissue engineering. Its exosomes (AD-SVF Exo), as cell-free products stable under ischemic conditions, represent an ethical and attractive modality for dental tissue regeneration and broader regenerative applications. Prior study indicates that AD-SVF Exo can enhance human dental pulp stem cell (hDPSC) migration and proliferation, particularly at low concentrations, but their detailed time- and dose-dependent proliferative effects remain unclear. This study aimed to investigate the time- and dose-dependent effects of low-concentration AD-SVF Exo on hDPSC proliferation …

In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami

Journal of Dentistry Indonesia

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach.

Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond …

Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu

Journal of Dentistry Indonesia

Background: This study aimed to evaluate canal transportation, centering ability, structure model index (SMI), surface area, and root canal volume changes in the mesial canals of mandibular first molars using micro-CT.

Methods: Twenty-four mandibular first molars with two separate mesial canals and moderate curvature were included. Teeth were scanned using micro-CT before instrumentation and randomly divided into three groups (N = 8). Root canals were prepared using OneShape, OneCurve, and Rotate file systems, followed by post-instrumentation micro-CT scanning (10µm/pixel resolution). Changes in canal volume, surface area, transportation, centering ability, and SMI were analyzed at the apical, middle, and …

Evaluation Of An Audiovisual Educational Tool With Reinforcement Messages For Orthodontic Patients: A 6-Month Randomized Controlled Trial, Laura Restrepo Quijano, Maria Paula Vasco Gomez, Natalia Hurtado Velasquez, Luis Fabian Benitez Moreno

Journal of Dentistry Indonesia

Background: Orthodontic treatment increases the risk of bacterial plaque accumulation; therefore, oral hygiene education is essential to prevent complications, but its impact is usually limited when it is not reinforced with effective tools. This study aims to evaluate an audiovisual educational tool with reinforcement messages, compared with a verbal explanation about the proper use of the orthodontic oral hygiene kit.

Methods: This was a randomized controlled trial that included 62 patients randomly assigned to an intervention group: 31 patients who received an educational video plus three reinforcement messages via WhatsApp, and a control group: 31 patients who received …

Sinus Formation As A Manifestation Of Chronic Periodontitis In Mandibular Anterior Region: A Report On 2 Cases, Anisha Kumari, Shikha Tewari

Journal of Dentistry Indonesia

Background: Periodontitis is defined as an inflammatory disease of the supporting tissues of the teeth caused by specific microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone. Clinical manifestations of Persistent chronic periodontitis may mimic varied clinical manifestations, including those of apical abscess and systemic involvement.

Case report: This report presents the management of an intraoral sinus mimicking a chronic apical abscess in the mandibular anterior region associated with deep periodontal pockets in two male patients in their early thirties. With careful clinical and radiological examination and ruling out of endodontic and systemic involvement, the …

Antibacterial And Antibiofilm Effects Of Ziziphus Mauritiana Leaf Extract Against Staphylococcus Aureus, Wiwiek Poedjiastoeti, Irvan Septrian Syah Putra Rasad, Felicia Klarissa Tanzil, Indrayadi Gunardi, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Background: Tooth extraction is a common dental procedure often complicated by postoperative infections, with Staphylococcus aureus as a key opportunistic pathogen. Rising antibiotic resistance and side effects of conventional antiseptics like chlorhexidine highlight the need for natural alternatives. This study evaluated the antibacterial and antibiofilm potential of 96% ethanol extract from Ziziphus mauritiana leaves against S. aureus.

Methods: The extract was prepared by maceration and tested in vitro using microdilution for minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against S. aureus ATCC 25923. Antibiofilm activity was assessed via crystal violet staining on mature biofilms, with …

Correlation Between Maxillary Morphology And Sinus Dimensions In Skeletal Class I, Ii, And Iii Subjects: A Comparative Study, Nida Shaikh, Dipti Shastri, Pradeep Tandon, Gyan Prakash Singh

Journal of Dentistry Indonesia

Background: This study aimed to evaluate variations in maxillary and sinus morphology and their correlations with skeletal malocclusion patterns using CBCT.

Methods: This retrospective study analyzed CBCT records of 70 subjects aged 17–40 years, divided into three groups: Skeletal Class I (N = 25), Class II (N = 25), and Class III (N = 20). Five maxillary skeletal and four sinus parameters were assessed. Intergroup comparisons were performed using one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test. Correlations were evaluated using Pearson’s correlation test. Intra-observer reliability was assessed by re-measuring 8 randomly selected CBCT scans …

Retrospective Cbct Evaluation Of Missed Root Canals And Their Association With Periapical Lesions In A Makkah-Based Population, Mashael Alqahtani, Samia Mohamed Elsherief, Ibtesam Kamel Afifi

Journal of Dentistry Indonesia

Background: Missed root canals are common and can cause persistent periapical disease, making the assessment of their prevalence essential for improving diagnostic accuracy and treatment outcomes. This study aimed to investigate the prevalence of missed canals and evaluate their association with periapical lesions in root canal–treated teeth in the Makkah population.

Methods: This retrospective cross-sectional study analysed 815 cone-beam computed tomography scans obtained from Umm Al-Qura University between 2019 and 2024. Missed canals and their association with periapical lesions were assessed by two independent observers. Statistical analysis was performed using the chi-square test.

Results: Missed canals were …

Comparison Of Chatgpt, Claude Ai, And Dental Students In The Detection Of Artifacts On Panoramic Radiography, Elif Çeçen Erol, Ceren Aktuna Belgin, Gözde Serindere, Kaan Gunduz

Journal of Dentistry Indonesia

Background: Accurate radiographic diagnosis requires images obtained with proper technique. Artifacts are unwanted irregularities or densities not produced by the primary X-ray beam and may obscure anatomical details in radiographic images. This retrospective study aimed to evaluate the performance of ChatGPT, Claude AI, and intern dental students in detecting artifacts in panoramic radiographs (PRs).

Methods: Between January and December 2024, panoramic radiographs of 40 patients containing 74 artifacts (motion, mispositioning, airway/soft tissue, and foreign body/metal artifacts) were retrospectively evaluated. The artifact detection performance of ChatGPT-4.0, Claude AI 3.5 Sonnet, and intern dental students was subsequently evaluated and compared …

Oral Health Behaviors And Oral Health Status In Elementary School Children In East Kalimantan, Indonesia, Lia Hapsari Andayani, Amabelle Elisanditya, Abdul Gani Soulisa, Sri Lestari

Journal of Dentistry Indonesia

Background: Children's oral health can be influenced by various factors, including health behaviors, dietary patterns, and oral health knowledge. This study aimed to determine the correlation between oral health behaviors and oral health status in elementary school children.

Methods: This cross-sectional study involved 182 elementary school children in Bontang, East Kalimantan, taken by convenience sampling. Health behavior data were acquired by 12-item questionnaires based on the WHO guideline. Examination of dental and oral health status was done by using the DMFT Index and OHI-S. Chi-square was used to determine the correlation between oral health behaviors and oral health …

Smoking Habits And Attitudes Of Dental, Nursing And Pharmacy Students, Daniel M. Laskin Dds, Ms, Caroline K. Carrico

Virginia Dental Journal

No abstract provided.

Contribution Of The M1 Vs M2 Phenotype Toward Macrophage Interactions With Streptococcus Mutans, The Dominant Bacteria In The Oral Cavity, Isabelle K. Wintz

Honors Thesis

We are all exposed to numerous pathogens every day. One of the sites for pathogens to interact with our body is in the mouth. To better understand these interactions between bacteria and host immune cells, I developed an assay to study the oral bacteria Streptococcus mutans and inflammatory macrophages. Our hypothesis was that the cytokines IL-4 and IFN-y would alter macrophage phenotypes with IL-4 reducing inflammatory responses and IFN-y increasing inflammation.  To test this, we performed experiments in cell culture as a first step toward understanding the severity of the host response at the cellular and molecular levels. Our results …

The Accuracy Of Occlusal Splint Fabricated By The Different Materials With Different 3d Printers., Supisara Thamrongsak

Master's Theses (2009 -)

Aim: The purpose of this study is to evaluate the accuracy of occlusal splints fabricated by the different materials with different 3D printers in four different orientations (0°, 15°, 25°, 40°) using surface matching software. Materials and Methods: Occlusal splints were printed in 4 different orientations including 0°, 15°, 25°, and 40° based on the STL file of the designed occlusal splint with 3 different printers (Carbon® M3Max, SprintRay Pro S, Asiga Pro4K). A total of 120 occlusal splints were printed for the present study, 10 occlusal splints were printed for each group. Then all occlusal splints were scanned using …

Garlic Breath And Beads Of Sweat: The Effects Of Garlic And Chili Peppers On The Growth And Ph Of Streptococcus Mutans., Lena Pitzer

Honors Projects

The purpose of this project is to provide a quantifiable and repeatable measurement of how the presence of garlic and chili pepper during the growth of a carious dentine strain of Streptococcus mutans affects the growth of the strain and surrounding pH level.This research project examines two possible alternative agents, garlic and chili peppers, due to the known antimicrobial effects of their active components, allicin and capsaicin. Prepared garlic and chili extracts were used during disk diffusion to assess and measure the zones of inhibition. The anticipated results are that there will be inhibition present with both the garlic and …

Digital Assessment Of Subtractive And Additive Cad/Cam Fabrication Methods On The Fit And Accuracy Of Lithium Disilicate Veneers, Basma Refaat Fayad, Islam Heiba Dr, Sara Fikry Dr, Maha Nagy

Dentistry

Objectives: This study compared subtractive and additive fabrication methods regarding their impact on the marginal/internal fit, trueness, and precision of lithium disilicate ceramic veneers. Methods: Laminate veneer preparations on an acrylic tooth were duplicated into twenty-four additively manufactured resin dies. Veneers were digitally designed and fabricated via milling (subtractive) or 3D-printing (additive) (n=12/group). All veneers were scanned. For trueness, the final design served as the reference; for precision, pairwise comparisons were made within each group. For adaptation, the scanned die was the reference. Post-cementation and thermal cycling (10,000 cycles, 5–55°C), marginal adaptation was measured using a digital microscope (×100). Data …

Functional Genomics Of Streptococcus Mutans: Identifying Critical Genes For Oral Biofilm Formation, Cara E. Pirani

Create@State

Streptococcus mutans (S. mutans) is a pathogen found in the human oral cavity that plays a central role in the development of dental caries, or tooth decay. This pathogen thrives on the sugars consumed in the diet, contributing to the breakdown of tooth enamel, especially in the presence of poor oral hygiene. S. mutans produces a glycosyltransferase enzyme that converts sucrose into the polysaccharide glucan. Glucan allows the pathogen to attach to the enamel of the tooth and begin metabolizing the sugar on the teeth, resulting in lactic acid. The acid under the biofilm layer lowers the pH of the …

Inhibitory Effects Of Novel Compounds On Biofilm Formation In Streptococcus Mutans, Graysen S. Jones

Create@State

Inhibitory Effects of Novel Compounds on Biofilm Formation in Streptococcus mutans

Exploring Systemic Challenges In The Western North Carolina Dental Safety Net: A Qualitative Analysis, Blaire Mirmow, Bill Milner, Nadia Laniado

Journal of Appalachian Health

Introduction: Despite statewide growth, rural communities in Western North Carolina (WNC) face persistent barriers to oral health care driven by chronic dental workforce shortages and systemic geographic disparities. Within this Appalachian region, the dental safety net serves as a vital yet strained support system, struggling with limited financial resources and a lack of provider participation that leaves many underserved populations without essential oral health services.

Purpose: This study aims to explore the experiences of individuals working within the WNC dental safety net to identify barriers and strategies required to strengthen the delivery of oral health care in high-need rural settings. …

Patient Perception Of Pain Following Extraction And Bone Graft With Or Without Preemptive Ibuprofen: A Randomized Clinical Trial, Samah Rady

Master's Theses (2009 -)

Objective: The purpose of this randomized clinical trial is to investigate the effects of preemptive analgesia on postoperative pain following extraction and ridge preservation and to evaluate the association between dental care-related fear and anxiety, health literacy, fear of pain, and pain catastrophizing with post-operative pain and swelling perception as well as Oral Health Impact Profile-14 (OHIP-14). Materials and Methods: Ibuprofen 600mg (test; n=9) or placebo (n=13) were randomly given one hour prior to extraction and ridge preservation. Preoperatively, patients completed the following questionnaires: Modified Dental Anxiety Scale (MDAS), Oral health-related quality of life (OHIP-14), Fear of Pain (FPQ-III), Pain …

Potential Applications Of Thymus Vulgaris In Dental Care: A Review Of Antimicrobial And Oral Health Benefits, Lakenzia Z. Ham

Undergraduate Research Conference

This research proposal focuses on how common thyme (Thymus vulgaris) can be used in dental care. There has been more interest in natural products for dental health because some common dental treatments can have side effects or lead to antibiotic resistance. Thyme contains natural compounds like thymol and carvacrol that help kill bacteria, reduce inflammation, and prevent buildup on teeth.

The purpose of this study is to investigate the current scientific literature to see the effectiveness of thyme in preventing common oral health problems like cavities, gum disease, and bad breath. Research shows that thyme can fight bacteria …

Perspectives On An Unconventional Partnership Between Occupational Therapists And Pediatric Dental Professionals, Marissa Holsonback, Reeti Douglas, Leslie Gazdeck

The Open Journal of Occupational Therapy

Pediatric clients with disabilities are at increased risk for dental problems, including periodontal disease. Developmental delay and sensory processing dysfunction hinder acceptance of the stimulating dental environment and engagement in oral care routines at home. This health disparity is magnified by many dental professionals’ lack of training and confidence with children who have special needs. The holistic occupational therapy scope of practice is inclusive of oral care, pediatric diagnoses, sensory integration, and behavior management, allowing occupational therapists to collaborate with pediatric dental professionals to address the oral health disparity. This perspective manuscript provides occupational therapists with an evidence-supported understanding of …

The Influence Of The Timing Of Definitive Restoration Placement After Root Canal Completion: A 22-Year Retrospective Study, Shikha Gupta

Master's Theses (2009 -)

Objective: To evaluate how the time interval between root canal obturation and the placement of a definitive restoration impacts the incidence of tooth failure, defined as non-surgical retreatment, apical surgery, or extraction. Methods: This 22-year-retrospective cohort study utilized electronic health records from the Marquette University School of Dentistry (MUSoD) axiUm database, analyzing 11,002 teeth treated between 2004 and 2026. Inclusion criteria required patients to be at least 18 years of age, categorized as established patients of record, with all non-surgical root canal treatments (NSRCT) meeting the 2020 AAE quality standards. The interval between obturation and restoration was categorized into seven …

Dr. Mark Crabtree Puts Community Service At The Forefront Of His Profession, Mackenzie Meleski

Virginia Dental Journal

No abstract provided.

Awards And Recognition

Virginia Dental Journal

No abstract provided.

Mountain Empire Community College Sponsors Fourth Annual Give Kids A Smile! Day, Emily Kate Bowen Dds, Ma, Mph

Virginia Dental Journal

No abstract provided.

Creating A Brand Identity For Your Dental Practice, Kelly O'Keefe

Virginia Dental Journal

No abstract provided.

What Patients Believe — And What They're Actually Doing, Michael Weitzner Dds

Virginia Dental Journal

No abstract provided.

The Dental Oenophile, Zaneta Hamlin Dds

Virginia Dental Journal

No abstract provided.

Virginia Board Of Dentistry Meeting Notes March 6, 2026, Ursula Klostermyer Dds, Phd

Virginia Dental Journal

No abstract provided.

Practicing Ethical Patient Selection: Applying The Ada Principles In Everyday Care, Adel Rizkalla Dds

Virginia Dental Journal

No abstract provided.