Dentistry Commons^™

Pseudomyogenic Hemangioendothelioma: A Vascular Tumor Previously Undescribed In The Oral Cavity, Yeshwant B. Rawal, Kenneth M. Anderson, Thomas B. Dodson

School of Dentistry Faculty Research and Publications

The pseudomyogenic hemangioendothelioma (PMH) is a low-grade malignant vascular neoplasm of different tissue planes including skin and soft tissue. Primary tumors in the skeletal muscle and bone have also been diagnosed. The PMH was introduced into the WHO classification of tumors of soft tissue and bone in 2013. This is the first description of oral involvement. A 21-year-old female presented with a 2-month old swelling of her gingiva. The swelling appeared red in color and was soft in consistency. A clinical diagnosis of a pyogenic granuloma was made and an incisional biopsy was submitted for histopathological evaluation. The lesion consisted …

Divergent Schwannoma-Like Phenotype In A Pleomorphic Adenoma, Srinivasa R. Chandra, Farah Karim, Yeshwant B. Rawal

School of Dentistry Faculty Research and Publications

The schwannoma-like pleomorphic adenoma is a rare histopathological variant of the pleomorphic adenoma. Five previous reports with seven cases exist in English language literature. These tumors present in the parotid gland most commonly. Intraparotid schwannomas of the facial nerve and schwannomas with glandular differentiation have also been reported. A 60-year-old male presented with an asymptomatic swelling over the left angle of the mandible. The swelling had been present for about 12 years with a recent increase in size. CT imaging showed a hyperdense circumscribed mass of the superficial lobe of the parotid. The working diagnosis was that of a benign …

Prosthetic Rehabilitation Following Lateral Resection Of The Mandible With A Long Cantilever Implant-Supported Fixed Prosthesis: A 3-Year Clinical Report, Georgios Maroulakos, William W. Nagy, Ayman Ahmed, Ioli I. Artopoulou

School of Dentistry Faculty Research and Publications

This clinical report describes the prosthetic management of the surgical reconstruction of a patient after mandibular resection. Complete oral rehabilitation was achieved with a maxillary complete denture and a mandibular implant-supported fixed prosthesis with a custom titanium framework and a long unilateral cantilever.

3d Printed Tcp-Based Scaffold Incorporating Vegf-Loaded Plga Microspheres For Craniofacial Tissue Engineering, Farahnaz Fahimipour, Morteza Rasoulianboroujeni, Erfan Dashtimoghadam, Kimia Khoshroo, Mohammadreza Tahriri, Doug Lobner, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Objective

Vascularization is a critical process during bone regeneration/repair and the lack of tissue vascularization is recognized as a major challenge in applying bone tissue engineeringmethods for cranial and maxillofacial surgeries. The aim of our study is to fabricate a vascular endothelial growth factor (VEGF)-loaded gelatin/alginate/β-TCP composite scaffold by 3D printing method using a computer-assisted design (CAD) model.

Methods

The paste, composed of (VEGF-loaded PLGA)-containing gelatin/alginate/β-TCP in water, was loaded into standard Nordson cartridges and promptly employed for printing the scaffolds. Rheological characterization of various gelatin/alginate/β-TCP formulations led to an optimized paste as a printable bioink at room …

S-100 Negative Granular Cell Tumor (So-Called Primitive Polypoid Non-Neural Granular Cell Tumor) Of The Oral Cavity, Yeshwant B. Rawal, Thomas B. Dodson

School of Dentistry Faculty Research and Publications

Four cases of cutaneous S-100 negative granular cell tumor were described in 1991. Until now, only 3 cases of oral involvement have been documented in English literature. Two additional cases of oral S-100 negative granular cell tumor are described. Immunohistochemical markers were applied to exclude other lesions that may show the presence of granular cells. The clinical findings were correlated with the histopathological and immunohistochemical features to arrive at the appropriate diagnosis. S-100 negative granular cell tumors are erythematous polypoid masses commonly mistaken for granulation tissue or a pyogenic granuloma. Any part of the oral cavity may be affected. Histopathologically, …

Evaluation Of Die Trim Morphology Made By Cad-Cam Technology, Pratiksha Agrawal, Geoffrey A. Thompson, Seok-Hwan Cho, Gerald J. Ziebert

School of Dentistry Faculty Research and Publications

Statement of problem

The die contour can affect the emergence profile of prosthetic restorations. However, little information is available regarding the congruency between a stereolithographic (SLA) die and its corresponding natural tooth.

Purpose

The purpose of this vitro study was to evaluate the shapes of SLA die in comparison with the subgingival contour of a prepared tooth to be restored with a ceramic crown.

Material and methods

Twenty extracted human teeth, 10 incisors, and 10 molars, were disinfected and mounted in a typodont model. The teeth were prepared for a ceramic restoration. Definitive impressions were made using an intraoral scanner …

Thermal Properties Of Commonly Used Clear Aligner Systems As-Received And After Clinical Use, Louis Wenger

Master's Theses (2009 -)

Background/Objectives: The purpose of this study was to investigate the thermal properties, particularly glass transition temperature, of the polymers that are used to fabricate three different types of modern orthodontic aligners. Invisalign, (Align Technology, Inc, Santa Clara, CA, USA), Simpli5 (Allesee Orthodontic Appliances, Sturtevant, WI, USA), and ClearCorrect (ClearCorrect, Round Rock, TX, USA) were examined both as-received and after clinical use to determine if any differences were present both between and within aligners. Materials/Methods: Orthodontic aligners were collected from three different patients using the systems under investigation after two weeks of intraoral use. Duplicate, un-used samples were obtained from the …

Direct Visual Approximation Of Arch Length Discrepancy And Cephalometric Measurements, Bradley J. Wurm

Master's Theses (2009 -)

Introduction: Arch length discrepancy and cephalometric analysis are critical components of orthodontic treatment planning. Both have direct effects on the decision to extract teeth or not and treatment mechanics as well. Visual approximation is the most common method used to analyze arch length discrepancy among practitioners. Current trends show a decrease in the amount of orthodontists completing a cephalometric analysis. Previous studies have shown a tendency for orthodontists to overestimate the degree of crowding when visually approximating on dental casts. No previous study has assessed the ability to visually approximate cephalometric angle measurements. The purpose of this survey was to …

Effects Of Palatal Expansion On Speech Production, Jason Milton Meinhardt

Master's Theses (2009 -)

Introduction: Rapid palatal expanders (RPEs) are a commonly used orthodontic adjunct for the treatment of posterior crossbites. RPEs are cemented to bilateral posterior teeth across the palate and thus may interfere with proper tongue movement and linguopalatal contact. The purpose of this study was to identify what specific role RPEs have on speech sound production for the child and early adolescent orthodontic patient. Materials and Methods: RPEs were treatment planned for patients seeking orthodontics at Marquette University. Speech recordings were made using a phonetically balanced reading passage (“The Caterpillar”) at 3 time points: 1) before RPE placement; 2) immediately after …

Ultraviolet-Induced Surface Grafting Of Octafluoropentyl Methacrylate On Polyether Ether Ketone For Inducing Antibiofilm Properties, Parisa Amdjadi, Hanieh Nojehdehian, Farhood Najafi, Amir Ghasemi, Massoud Seifi, Erfan Dashtimoghadam, Farahnaz Fahimipour, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Since octafluoropentyl methacrylate is an antifouling polymer, surface modification of polyether ether ketone with octafluoropentyl methacrylate is a practical approach to obtaining anti-biofilm biocompatible devices. In the current study, the surface treatment of polyether ether ketone by the use of ultraviolet irradiation, so as to graft (octafluoropentyl methacrylate) polymer chains, was initially implemented and then investigated. The Fourier-transform infrared and nuclear magnetic resonance spectra corroborated the appearance of new signals associated with the fluoroacrylate group. Thermogravimetric curves indicated enhanced asymmetry in the polymer structure due to the introduction of the said new groups. Measuring the peak area in differential scanning …

Opioid Analgesic Prescribing Practices Of Dental Professionals In The United States, C. N. Steinmetz, C. Zheng, Elaye Okunseri, Aniko Szabo, Christopher Okunseri

School of Dentistry Faculty Research and Publications

The prescription of opioid analgesics by dental professionals is widespread in the United States. Policy makers, government agencies, and professional organizations consider this phenomenon a growing public health concern. This study examined trends in the prescription of opioid analgesics for adults by dental professionals and associated factors in the United States. Data from the Medical Expenditure Panel Survey (1996-2013) were analyzed. Descriptive statistics were calculated separately for each year. Logistic regression analyses were conducted to estimate the overall trend during the period with and without adjusting for dental procedures and personal characteristics. Survey weights were incorporated to handle the sampling …

The Effect Of Heat Treatment On The Bending Properties Of A Cobalt-Chromium Orthodontic Wire, Alex Schwab

Master's Theses (2009 -)

Introduction: Elgiloy, a brand name of the original cobalt-chromium orthodontic wire, has been around for more than 50 years; yet despite this, little literature is available. Most of the literature on Elgiloy wires tends to evaluate the wires in tension. For these reasons, this study aimed to determine the bending properties of the four available tempers of Elgiloy wires and how heat treatment affects the wires’ bending properties. Materials and Methods: All four tempers of Elgiloy (red, yellow, green, and blue) were ordered in straight lengths containing 20 wires per pack that are each 0.018 inches in diameter and 14 …

Reliability Of Digital Dental Cast Measures As Compared To Cone-Beam Computed Tomography For Analyzing The Transverse Dimension, Brian Michel

Master's Theses (2009 -)

The purpose of this study was to assess the consistency in diagnosing the transverse dimension on cone-beam computed tomography (CBCT) images as compared to digital dental models. The study consisted of 11 patients with posterior crossbite at the level of the first molar and 17 patients with no crossbite at the level of the first molar. 13 patients were male and 15 patients were female with an overall mean age of 13.6 years. Eight linear measurements and two angular measurements were made on CBCT images of the patients and six linear measurements were made on the corresponding digital dental casts. …

Hairy Tongue, Marc Zachary Handler, David F. Butler, Drore Eisen, Jeff Burgess, Denis P. Lynch, Gary L. Stafford

School of Dentistry Faculty Research and Publications

Hairy tongue (lingua villosa) is a commonly observed condition of defective desquamation of the filiform papillae that results from a variety of precipitating factors. ^[1] The condition is most frequently referred to as black hairy tongue (lingua villosa nigra); however, hairy tongue may also appear brown, white, green, pink, or any of a variety of hues depending on the specific etiology and secondary factors (eg, use of colored mouthwashes, breath mints, candies). ^{[2, 3]} See the images below:

Oral Health And Dental Anxiety In A German Practice-Based Sample, Arndt Guentsch, Christiane Stier, Gregor F. Raschke, Andre Peisker, Mina D. Fahmy, Harald Kuepper, Ina Schueler

School of Dentistry Faculty Research and Publications

Objective

Does dental anxiety have an effect on dental and periodontal health?

Methods

Survey data was collected from n = 200 adults (53 % females, average age 49 years) in a cross-sectional study. Dental anxiety was measured with the modified dental anxiety scale (MDAS, score 1–5, the greater the score, the greater the anxiety). Clinical parameters including probing depth (PD), clinical attachment level (CAL), plaque index (SLI), and bleeding on probing (BoP) as well as the DMFT index were recorded and statistically analyzed.

Results

Rating of dental anxiety was higher in women than in men (65 vs 35 %). Subjects …

Central Xanthoma Of The Jaw Bones: A Benign Tumor, Yeshwant B. Rawal, Srinivasa R. Chandra, James M. Hall

School of Dentistry Faculty Research and Publications

Extragnathic xanthomas are seen in the bones or as soft tissue masses. They are often associated with hyperlipidemia and are considered as reactive or metabolic lesions. Only 19 cases of xanthomas of the jaws have been reported so far in the English literature. A total of ten cases of central xanthoma of the jaw bones were identified from the Oral and Maxillofacial Pathology biopsy services of the University of Washington and the Tufts University School of Dental Medicine, between the years 2000–2016. The demographic and clinical information on these cases was tabulated logically on the basis of age, gender, location …

A Method Of Facilitating The Fabrication Of Access Openings For Implant-Supported Complete Fixed Dental Prostheses, Seok-Hwan Cho, Geoffrey A. Thompson

School of Dentistry Faculty Research and Publications

This report describes a method for fabricating access openings for implant-supported complete fixed dental prostheses (ICFP) by using a dental milling machine and silicone putty matrix. The method can help clinicians achieve the accurate and precise fabrication of access openings for ICFPs without excessive grinding.

Development Of A Dna-Liposome Complex For Gene Delivery Applications, Morteza Rasoulianboroujeni, G. Kupgan, F. Moghadam, A. Boughdachi, Payam Khoshkenar, J. J. Ambrose, N. Kiaie, Daryoosh Vashaee, J. D. Ramsey, Lobat Tayebi

School of Dentistry Faculty Research and Publications

The association structures formed by cationic liposomes and DNA(Deoxyribonucleic acid)-liposome have been effectively utilized as gene carriers in transfection assays. In this research study, cationic liposomes were prepared using a modified lipid film hydration method consisting of a lyophilization step for gene delivery applications. The obtained results demonstrated that the mean particle size had no significant change while the polydispersity (PDI) increased after lyophilization. The mean particle size slightly reduced after lyophilization (520 ± 12 nm to 464 ± 25 nm) while the PDI increased after lyophilization (0.094 ± 0.017 to 0.220 ± 0.004). In addition. The mean particle size …

Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and non-ketotic hyperosmolar coma. In addition, possible long-term complications include impotence, nerve damage, stroke, chronic kidney failure, cardiovascular disease, foot ulcers, and retinopathy. Historically, universal methods to measure glycemic control for the diagnosis of diabetes included fasting plasma glucose level (FPG), 2-h plasma glucose (2HP), and random plasma glucose. However, these measurements did not provide information about glycemic control over a long period of time. To …

Hairy Leukoplakia, James E. Cade, Richard P. Vinson, Jeff Burgess, Sanjiv S. Agarwala, Denis P. Lynch, Gary L. Stafford

School of Dentistry Faculty Research and Publications

Oral hairy leukoplakia (OHL) is a disease of the mucosa first described in 1984. This pathology is associated with Epstein-Barr virus (EBV) and occurs mostly in people with HIV infection, both immunocompromised and immunocompetent, and can affect patients who are HIV negative. ^{[1, 2]} The first case in an HIV-negative patient was reported in 1999 in a 56-year-old patient with acute lymphocytic leukemia. Later, many cases were reported in heart, kidney, and bone marrow transplant recipients and patients with hematological malignancies. ^{[3, 4]}

Salivary Mmp-9 In The Detection Of Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Mina D. Fahmy, Arndt Guentsch, Korosh Roshanghias, Joschka Hennings, Stefan Schultze-Mosgau

School of Dentistry Faculty Research and Publications

Background: Oral squamous cell carcinoma (OSCC) is the most common malignant tumour of the oral cavity. Detection of OSCC is currently based on clinical oral examination combined with histopathological evaluation of a biopsy sample. Direct contact between saliva and the oral cancer makes measurement of salivary metalloproteinase- 9 (MMP-9) an attractive alternative.

Material and Methods: In total, 30 OSCC patients and 30 healthy controls were included in this prospective study. Saliva samples from both groups were collected, centrifuged and supernatant fluid was subjected to ELISA for assessment of MMP-9. The median salivary MMP-9 values with interquartile range (IQR) of OSCC …

Interleukin-6 Expression In Disc Derangement Of Human Temporomandibular Joint And Association With Osteoarthrosis, Flavio Camejo, Marina Azevedo, Viviane Ambros, Karina Caporal, Andrea Doetzer, Luis Eduardo Almeida, Marcia Olandoski, Lucia Noronha, Paula C. Trevilatto

School of Dentistry Faculty Research and Publications

The inflammatory process is a coordinated response that protects host after infection or trauma, involving several molecular reactions. Once the inflammation is closely linked to the process of destruction of the temporomandibular joint, this study aims to examine, by immunohistochemistry, the expression of interleukin-6 (IL-6), an important inflammatory marker, in temporomandibular articular discs of patients with anterior disc displacement with (ADDwR) and without reduction (ADDwoR) and its association with osteoarthrosis (OA). Thirty-eight (n = 38) articular discs were divided into two cutoffs: 1) analysis 1: 4 control (acute pathology), 17 ADDwR, 17 ADDwoR; and 2) analysis 2: without OA (n …

From Solvent-Free Microspheres To Bioactive Gradient Scaffolds, Morta Rasoulianboroujeni, Mostafa Yazdimamaghani, Payam Khoshkenar, Venkata Raveendra Pothineni, Kwang-Min Kim, Teresa A. Murray, Jayakumar Rajadas, David K. Mills, Daryoosh Vashaee, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

A solvent-free microsphere sintering technique was developed to fabricate scaffolds with pore size gradient for tissue engineering applications. Poly(D,L-Lactide) microspheres were fabricated through an emulsification method where TiO₂ nanoparticles were employed both as particulate emulsifier in the preparation procedure and as surface modification agent to improve bioactivity of the scaffolds. A fine-tunable pore size gradient was achieved with a pore volume of 30 ± 2.6%. SEM, EDX, XRD and FTIR analyses all confirmed the formation of bone-like apatite at the 14^th day of immersion in Simulated Body Fluid (SBF) implying the ability of our scaffolds to bond to …

Predoctoral Dental Students’ Perceptions Of Dental Implant Training: Effect Of Preclinical Simulation And Clinical Experience, Soni Prasad, Naveen K. Bansal

School of Dentistry Faculty Research and Publications

The aims of this study were to assess 1) differences in perceptions of dental implant training between dental students who received didactic training alone (control group) and those who received didactic plus simulation training (test group); 2) differences in response between students with and without clinical experience in implant dentistry; and 3) the interaction effect of simulation training and clinical experience on students’ satisfaction. A survey was distributed to the control group in 2014 and to the test group in 2015; both groups were at the same U.S. dental school. Data were collected on confidence levels with various implant restorative …

Analysis Of Flexural Strength And Monotonic Load To Failure Following Simulated Chairside Adjustments And Repair In A Lithium Disilicate Glass-Ceramic, Ali Ramadhan

Master's Theses (2009 -)

Introduction: There are no studies regarding e.max Press that evaluate post-adjustment healing protocols and their effect on the load to failure in a clinically relevant test. It is essential to find the ultimate treatment protocol which will help clinicians preserve the physical properties of the ceramic restoration after adjustment. Material and Methods: The total number of samples used in this study was 440 IPS e.max press discs. The discs were 15 mm in diameter and 1 mm of thickness. The material was tested for flexural strength and monotonic load to failure. The test was done in two parts and with …

Comparison Of Anterior Denture Teeth Arrangements Made With The Tooth Mold Template And Definitive Computer-Aided Design & Computer-Aided Manufacturing Complete Removable Dental Prostheses, Jose Antonio Sierra

Master's Theses (2009 -)

Introduction: There is a dearth of information in the refereed literature regarding esthetics of CAD/CAM complete removable dental prostheses (CRDPs). The purpose of this study was to investigate and compare the anterior denture teeth arrangement made with the medium-size anterior tooth mold template to CAD/CAM complete removable dental prostheses fabricated with bonded denture teeth and milled teeth. Material and methods: Poly-vinyl siloxane impression were made of an edentulous maxillary model and selected for use as the patient template. The edentulous model was mounted on a semi-adjustable articulator. Definitive impressions and jaw relation records were made according to the manufacturer’s protocol. …

Qmix 2in1 And Naoci Precipitate: Documentation, Identification, And Exothermic Reaction, Gordon L. Barkley Iii

Master's Theses (2009 -)

Introduction: The aim of this study was to document and identify precipitate formation and exothermic reaction caused when mixing NaOCl and QMiX. Methods: Photography captured time-dependent changes when mixing NaOCl and QMiX at; 0 seconds, 30 seconds, 1 minute, 30 minutes, 1 hour, and 24 hours. A differential scanning calorimeter (DSC) was utilized in determination of heat flow while analyzing temperature change (°C), enthalpy (mJ), and time (seconds) for NaOCl with QMiX and NaOCl with 2% chlorhexidine (CHX). 1H Nuclear Magnetic Resonance (NMR) and 2D NMR (DOSY) spectroscopy analyzed precipitation formed from NaOCl and QMiX. Results: Digital photography documented immediate, …

Correlation Between Subjective Nasal Patency And Intranasal Airflow Distribution, Kevin P. Casey, Azadeh A.T, Borojeni, Lisa J. Koenig, John S. Rhee, Guilherme J.M. Garcia

School of Dentistry Faculty Research and Publications

Objectives

(1) Analyze the relationship between intranasal airflow distribution and subjective nasal patency in healthy and nasal airway obstruction (NAO) cohorts using computational fluid dynamics (CFD). (2) Determine whether intranasal airflow distribution is an important objective measure of airflow sensation that should be considered in future NAO virtual surgery planning.

Study Design

Cross-sectional.

Setting

Academic tertiary medical center and academic dental clinic.

Subjects and Methods

Three-dimensional models of nasal anatomy were created based on computed tomography scans of 15 patients with NAO and 15 healthy subjects and used to run CFD simulations of nasal airflow and mucosal cooling. Subjective nasal …

Survival Rates Of Primary Endodontic Therapy Following Core/Post And Crown Placement, Kandace Yee

Master's Theses (2009 -)

Introduction: The objective of this study was to determine if a correlation exists between the time to core or post and core (core/post) placement following non-surgical root canal therapy (NS RCT), the time to crown placement following core/post placement, and the incidence of an untoward event. Materials and Methods: Utilizing the Delta Dental of Wisconsin Insurance Database, information was analyzed from 476,479 initial NS RCT procedures. Of these teeth, 160,040 had a core/post and a crown placed before the end of the continuous coverage period or occurrence of an untoward event. Untoward events were defined as having a retreatment, apicoectomy, …

Viability Of Human Periodontal Ligament Fibroblasts After Time In Tooth Storage Media, Scott Macdonald

Master's Theses (2009 -)

Periodontal ligament cell viability at the time of tooth replantation is of utmost importance for proper repair of the damaged tissues (1). Multiple different options are currently available for storage of an avulsed tooth. The goal of this study was to investigate new storage media and evaluate their ability to maintain cell viability over time. Materials and Methods: Cultured human periodontal ligament fibroblasts (hPDLF) were seeded on 96-well plates. These cells were exposed to different storage media including: Hank’s Balanced Salt Solution (HBSS), EMT Toothsaver (EMT), Save-A-Tooth (SAT), trehalose (T300), cell culture media, water, and different formulations of HBSS combined …