Dentistry Commons^™

Serum Anti-Phosphorylcholine And Anti-Cardiolipin Concentrations Following Periodontal Scaling And Root Planing, Reve W. Chaston

Theses and Dissertations

Atherosclerosis is an insidious disease with serious morbidity and mortality including ischemic heart disease, stroke, and myocardial infarction. This condition is progressive and can start early in life eventually leading to large plaques and arterial occlusion. Two key components of this process are the immune system and lipids; in particular, LDL which accumulates within the arterial walls and macrophages which recognize and engulf oxidized-LDL (oxLDL) to form foam cells. Knowing that certain antibodies directed against bacterial antigens such as phosphorylcholine (PC) and cardiolipin (CL) show opsonizing cross-reactivity with oxLDL it can be proposed that there is a link between immune …

The Anti-Plaque Efficacy Of Listerine® Used In Combination With Toothbrushing In Orthodontic Patients, Zachary A. Casagrande

Theses and Dissertations

The bactericidal efficacy of Listerine®, the essential oil-containing mouthrinse, has long been recognized. The purpose of this study was to determine whether Listerine® mouthrinse, when added to the standard oral hygiene regimen, had an added benefit in reducing plaque and gingivitis development in orthodontic patients over a six-month period. 50 orthodontic patients from the Virginia Commonwealth University Department of Orthodontics were assigned either to the brushing + flossing (N= 25) or brushing + flossing + Listerine® (N = 25) group. At baseline (TI), measurements for the Ramfjord teeth were recorded for the gingival index, plaque index and bleeding index. Subsequent …

Use Of A Synthetic Substrate For Orthodontic Bond Strength Testing, Elijah B. Saikaly

Theses and Dissertations

In vitro bond strength studies are of great importance and interest since they allow the prediction of clinical success of orthodontic adhesives. There are many studies that have investigated bond strength values of bonding systems. However, due to the variation in the materials and methods employed, it is very difficult and often impossible to make comparisons among data. The use of a substrate as an alternate to enamel for mechanical tests would minimize these variables and reduce the challenges faced with in vitro bond strength tests. The purpose of this study was to investigate the suitability of Macor as a …

Oral Cancer Prevalence In Virginia, Karin C. Loftin, Michele Darby, Stacey Plichta, Sophie Thompson, Shreeram Kumar, Louis Abbey

Dental Hygiene Faculty Publications

Purpose. Oral and pharyngeal cancer affects 30,000 Americans a year and kills one fourth of those diagnosed. The primary risk factors for oral cancer are past or present cigarette and tobacco usage, and alcohol consumption in conjunction with tobacco use. Even though the prevalence of oral cancer is relatively low in the younger age groups, this group is most likely to benefit from intervention programs designed to change risky behavior such as smoking, and to prevent oral cancer in the later years. The goal of the study was to identify high-risk target areas for an oral cancer prevention program in …

The Comparative Effects Of 0.12% Chlorhexidine And Herbal Oral Rinse On Dental Plaque-Induced Gingivitis, Elizabeth N. Southern, Gayle B. Mccombs, S. L. Tolle, Ken Marinak

Dental Hygiene Faculty Publications

PURPOSE: The purpose of this study was to determine the effects of two oral rinses-one 0.12% chlorhexidine rinse (CHX) and one herbal rinse (HBR)-on gingival health status over time.

METHODS: Sixty-three participants were randomly assigned to one of three treatment groups: CHX, HBR, or placebo. For three months, participants rinsed twice daily (morning and evening) with (1/2) ounce of allocated rinse after brushing and flossing. Individuals were given the same type of soft bristle toothbrush and whitening toothpaste. No attempt was made to modify participants' routine oral care, except they were advised to refrain from use of any other oral …

Virginia Dental Journal (Vol. 83, No. 2, 2006)

Virginia Dental Journal

No abstract provided.

Tannerella Forsythia, A Periodontal Pathogen Entering The Genomic Era, Anne C. R. Tanner, Jacques Izard

Department of Food Science and Technology: Faculty Publications

Several questions need to be addressed to evaluate whether Tannerella forsythia is to be considered a periodontal pathogen. T. forsythia has been detected in periodontal health and disease, so could it be a pathogen? The species was not detected in many studies despite finding other putative pathogens, so could it be important in pathogenicity? The challenges of working with T. forsythia include its fastidious and anaerobic growth requirements for cultural detection. Thus, studies associating T. forsythia with periodontal and other oral infections have used noncultural approaches (immunoassays and DNA-based assays) in addition to cultural approaches. We feel …

Serum Decreases The Size Of Metafectene- And Genejammer-Dna Complexes But Does Not Affect Significantly Their Transfection Activity In Sccvii Murine Squamous Cell Carcinoma Cells, Krystyna Konopka, Nathan Overlid, Anitha C. Nagaraj, Nejat Düzgüneş

All Dugoni School of Dentistry Faculty Articles

Cationic liposome-DNA (lipoplexes) or polymer-DNA (polyplexes) complexes have been used to deliver therapeutic genes, both in vitro and in vivo. However, gene transfer by these non-viral vectors is usually inhibited by biological milieu. A relatively high efficiency of transfection could be achieved in human oral cancer cells transfected with the polycationic liposome, Metafectene, and the polyamine reagent, GeneJammer, in the presence of 60% fetal bovine serum (FBS) (Konopka et al., Cell. Mol. Biol. Lett. 10 (2005) 455-470). Here, we examined the efficacy of these vectors to deliver β-galactosidase (β-gal), luciferase and Herpes Simplex Virus thymidine kinase (HSV-tk) genes to SCCVII …

Micro-Computed Tomographic Analysis Of Bone Healing Subsequent To Graft Placement, Preeti M. Chopra

All ETDs from UAB

A MicroCT analysis of bone healing subsequent to graft (tri calcium phosphate/TCP) placement in the maxillary sinus prior to dental endosteal implant placement was the objective of the current study. Ten trephined rod shaped human bone cores were obtained three months after the placement of particulate graft material and the samples were stored immediately in 10% neutral buffered formalin. Using a Microcomputed tomography, the samples were evaluated at resolutions of 6 and 20μm. The thresholds for bone and graft material were determined using visual image, intensity (grey level) and histogram analyses. The graft and bone threshold was 235 greylevel and …

Aadej Comm 37 3&4 2006

AADEJ - The Communicator

The Communicator is the official journal of the American Association of Dental Editors and Journalists (AADEJ). It is published quarterly, distributed digitally via email to members, and posted on the Association's website, AADEJ.org. Each issue includes regular updates from the editorial team and AADEJ board, as well as feature articles on current issues in the field.

This is a combined issue for 2006, issue 3 and 4.

J Am Coll Dent 2006 73 1

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

The Effect Of Media Advertising On Consumer Perception Of Orthodontic Treatment Quality, Daenya T. Edwards

Theses and Dissertations

A survey instrument was designed to evaluate factors influencing consumer selection of an orthodontist and consumer perception of different forms of media advertising (radio, television, newspaper, magazine, direct mail, and billboard) by orthodontic practices. The surveys were distributed by 8 orthodontic offices in and around the Richmond, Virginia area. Out of 676 surveys, 655 (97%) were returned. Respondents most often cited dentist and patient referrals as how they learned of the orthodontic practices they visited (50%- 57%). However, a caring attitude and good practitioner reputation were cited as the top reasons influencing selection of an orthodontist (53% and 49% respectively). …

Treatment Effects Of Incisor Positioning On Anterior Tooth Display, Scott J. Eberle

Theses and Dissertations

The purpose of this study was to determine the effect of changes in maxillary incisor position on anterior tooth display (ATD) in adult (n = 21) and adolescent (n = 38) orthodontic patients. The effects of anterior-posterior, vertical, and angular changes of the maxillary central incisor position during orthodontic treatment were evaluated relative to changes in the amount of ATD measured from pretreatment (TI) and posttreatment (T2) lateral cephalometric radiographs of existing patient records.Results showed a significant relationship between starting ATD and ATD change during treatment for both adults (P = ,006) and adolescents (P

Soft Tissue To Hard Tissue Advancement Ratios For Mandibular Elongation Using Distraction Osteogenesis In Children, Michael B. Melugin, Pamela R. Hanson, Christopher A. Bergstrom, William I. Schuckit, T. Gerard Bradley

School of Dentistry Faculty Research and Publications

Distraction osteogenesis is extensively used for the elongation of hypoplastic mandibles in children, yet the soft tissue profile response to this is not well understood. The pre- and posttreatment lateral cephalometric radiographs of 27 pediatric patients who underwent bilateral mandibular elongation using distraction osteogenesis were analyzed retrospectively to correlate horizontal soft tissue advancement with horizontal underlying bone advancement at B point and pogonion. Horizontal advancement (in millimeters) of bone and overlying soft tissue at these points was collected from the radiographs of each patient, and linear regression analysis was performed to determine the relationship of hard to soft tissue horizontal …

Clinical And Experimental Applications Of Nir-Led Photobiomodulation, Kristina D. Desmet, David A. Paz, Jesse J. Corry, Janis T. Eells, Margaret T. T. Wong-Riley, Michele M. Henry, Ellen V. Buchmann, Mary P. Connelly, Julia V. Dovi, Huan Ling Liang, Diane S. Henshel, Ronnie L. Yeager, Deborah S. Millsap, Jinhwan Lim, Lisa J. Gould, Rina Das, Marti Jett, Brian D. Hodgson, David Margolis, Harry T. Whelan

School of Dentistry Faculty Research and Publications

This review presents current research on the use of far-red to near-infrared (NIR) light treatment in various in vitro and in vivo models. Low-intensity light therapy, commonly referred to as “photobiomodulation,” uses light in the far-red to near-infrared region of the spectrum (630–1000 nm) and modulates numerous cellular functions. Positive effects of NIR–light-emitting diode (LED) light treatment include acceleration of wound healing, improved recovery from ischemic injury of the heart, and attenuated degeneration of injured optic nerves by improving mitochondrial energy metabolism and production. Various in vitro and in vivo models of mitochondrial dysfunction were treated with a variety of …

Spatially-Oriented Emr For Dental Surgery, Min Wu, Lisa J. Koenig, John Lynch, Thomas S. Wirtz

School of Dentistry Faculty Research and Publications

As digital dental images become widely available, a new Electronic MR system (EMR) will be critical for the success of applying new technology to dental care. This project is designed an image-based and spatially-oriented EMR for dental surgery. A new panoramic image-based annotation model will be developed, which will complement dental charting precisely locating specific spatial findings for each patient. A spatially-oriented, multilayered data model for dental EMR will be developed using Geographic Information System (GIS) methods. This project will explore the possibility of applying head and neck images from VHP into a spatially-oriented EMR system.

Suppression Of The Tumorigenic Phenotype In Human Oral Squamous Cell Carcinoma Cells By An Ethanol Extract Derived From Freeze-Dried Black Raspberries, Kapila A. Rodrigo, Yeshwant B. Rawal, Robert J. Renner, Steven J. Schwartz, Qingguo Tian, Peter R. Larsen, Susan R. Mallery

School of Dentistry Faculty Research and Publications

Despite focused efforts to improve therapy, 5-yr survival rates for persons with advanced-stage oral squamous cell carcinoma (SCC) remain discouragingly low. Clearly, early detection combined with strategies for local intervention, such as chemoprevention prior to SCC development, could dramatically improve clinical outcomes. Previously conducted oral cavity human chemoprevention trials, however, have provided mixed results. Although some therapies showed efficacy, they were often accompanied by either significant toxicities or circulating antiadenoviral antibodies. It is clearly apparent that identification of nontoxic, effective treatments is essential to prevent malignant transformation of oral epithelial dysplasias. This study employed cell lines isolated from human oral …