Dentistry Commons^™

Fully Digital Workflow From Bone Augmentation To Implant-Supported Prosthetic Reconstruction, Ufuk Tatli, Koray Soygun, Orcan Yuksel

School of Dentistry Faculty Research and Publications

No abstract provided.

Are Sleeves Necessary In Static Computer-Assisted Implant Surgery? A Comparative In Vitro Analysis, Jenna Hang, Arndt Guentsch

School of Dentistry Faculty Research and Publications

Objectives

This study aims to examine differences in trueness and precision between surgical guides with (S) and without sleeves (SL). A secondary aim was to assess the impact of the sleeve-to-bone distance.

Materials and Methods

Mandible replicas (n = 120) were printed from an STL file obtained from a clinical CBCT. The mandibles were divided into sleeved (S, n = 60) and sleeveless (SL, n = 60) groups, each further divided into three categories (n = 20 each) with different heights from the guide to the implant platform: 2 mm (H2), 4 mm (H4), or 6 mm (H6). …

A Scoping Review Of Patient Safety Checklists In Dentistry, K. Zouaidi, T. W. Miner, M. F. Walji, E. Kalenderian, D. B. Rindal, K. J. Suda

School of Dentistry Faculty Research and Publications

Objectives

Not much is known about safety checklists use in dentistry. We aim to examine, assess, and provide a comprehensive understanding of the current knowledge concerning the use of checklists to improve patient safety in dentistry.

Methods

We conducted a comprehensive literature search using Medline and Embase for studies that use or describe the development of dental patient safety checklists. All study designs were included for citations published through December 2023.

Results

Following abstract and full-text screening, 27 studies remained for data extraction and analysis. Oral surgery emerged as the main dental specialty where the utilization and evaluation of checklists …

The Nature Of Adverse Events In Dentistry, Bunmi Tokede, Alfa Yansane, Muhammad F. Walji, D. B. Rindal, Don Worley, Joel White, Elsbeth Kalenderian

School of Dentistry Faculty Research and Publications

Objectives

Learning from clinical data on the subject of safety with regards to patient care in dentistry is still largely in its infancy. Current evidence does not provide epidemiological estimates on adverse events (AEs) associated with dental care. The goal of the dental practice study was to quantify and describe the nature and severity of harm experienced in association with dental care, and to assess for disparities in the prevalence of AEs.

Methods

Through a multistaged sampling procedure, we conducted in-depth retrospective review of patients’ dental and medical records.

Results

We discovered an AE proportion of 1.4% (95% CI, 1.1% …

Identifying Primary Proximal Caries Lesions In Pediatric Patients From Bitewing Radiographs Using Artificial Intelligence, Cesar D. Gonzalez, Zaid Badr, H. Cem Güngör, Shengtong Han, Manal Hamdan

School of Dentistry Faculty Research and Publications

Purpose: To develop a no-code artificial intelligence (AI) model capable of identifying primary proximal surface caries using bitewings among pediatric patients.

Methods: One hundred bitewing radiographs acquired at pediatric dental clinics were anonymized and reviewed. The inclusion criteria encompassed bitewing radiographs of adequate diagnostic quality of primary and mixed-dentition stages. The exclusion criteria included artifacts related to sensors’ quality, positioning errors, and motion. Sixty-six bitewing radiographs were selected. Images were uploaded to LandingLens™, a no-code AI platform. A calibrated consensus panel determined the presence or absence of proximal caries lesions on all surfaces (using ground truth labeling). The radiographs were …

Collagen: The Superior Material For Full-Thickness Oral Mucosa Tissue Engineering, Alexandra Gelin, Daniela S. Masson-Meyers, Fatemeh Amini, Keyvan Moharamzadeh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Background

Tissue engineering has significantly progressed in developing full-thickness oral mucosa constructs designed to replicate the natural oral mucosa. These constructs serve as valuable in vitro models for biocompatibility. testing and oral disease modeling and hold clinical potential for replacing damaged or lost oral soft tissue. However, one of the major challenges in tissue engineering of the oral mucosa is the identification of an appropriate scaffold with optimal porosity, interconnected porous networks, biodegradability, and biocompatibility. These characteristics facilitate cell migration, nutrient delivery, and vascularization. Various biomaterials have been investigated for constructing tissue-engineered oral mucosa models; collagen has demonstrated superior outcomes …

Electrochemical Properties Of Nickel-Titanium Rotary Endodontic Instruments, Vidyalakshmi Subramanian, Howard W. Roberts, Shengtong Han, Stephanie J. Sidow, David W. Berzins

School of Dentistry Faculty Research and Publications

Introduction

Nickel-titanium rotary endodontic files have been commercially available for decades, but more recent innovations have introduced heat-treated and surface-treated files. This study investigated the corrosion properties of various nickel-titanium files in normal saline and sodium hypochlorite (NaOCl).

Methods

Ten different file brands of size 40 with a 0.04 taper were subjected to electrochemical testing in 0.9% NaCl (saline) and 5.25% NaOCl at room temperature. The Open Circuit Potential (OCP) was observed for 1 hour followed by a cyclic polarization test from −300 to 700 mV and back to −300 mV (vs OCP). Nonparametric ANOVA and a pairwise comparison ( …

Learning From Data In Dentistry: Summary Of The Third Annual Openwide Conference, Elsbeth Kalenderian, Kawtar Zouaidi, Jan Yeager, Janelle Urata, Alfa Yansane, Bunmi Tokede, Donald B. Rindal, Heiko Spallek, Joel White, Muhammad F. Walji

School of Dentistry Faculty Research and Publications

The overarching goal of the third scientific oral health symposium was to introduce the concept of a learning health system to the dental community and to identify and discuss cutting-edge research and strategies using data for improving the quality of dental care and patient safety. Conference participants included clinically active dentists, dental researchers, quality improvement experts, informaticians, insurers, EHR vendors/developers, and members of dental professional organizations and dental service organizations. This report summarizes the main outputs of the third annual OpenWide conference held in Houston, Texas, on October 12, 2022, as an affiliated meeting of the American Dental Association (ADA) …

Traumatic Dental Injuries In Child, Adult And Elderly: Domestic Violence—Physical Abuse Hidden In Plain Sight, H. Cem Güngör

School of Dentistry Faculty Research and Publications

No abstract provided.

Comparison Of Dmft And Behavior Rating Scores Between Children With Systemic Disease And Healthy Children At The First Dental Visit, Gizem Erbaş Ünverdi, Beste Ozgur, H. Cem Güngör, Paul S. Casamassimo

School of Dentistry Faculty Research and Publications

Purpose: To evaluate and compare oral health and behavior scores at the first dental visit and dental treatment need using general anesthesia/sedation (GA/S) of children with systemic diseases (SD) and healthy children.

Methods: Data were obtained from healthy children (n = 87) and children with SD (n = 79), aged 4 to 6 years, presenting to a hospital dental clinic for a first dental examination. The total number of decayed, missing and filled teeth (dmft), dental behavior score using Frankl Scale, and dental treatment need using GA/S were recorded. Chi-square / Fisher’s exact test and Mann–Whitney U …

Exploring And Describing Current Behavioral And Social Sciences Curricula In Predoctoral Dental Programs, Casey D. Wright, Lance Brendan Young

School of Dentistry Faculty Research and Publications

Purpose

To maintain accreditation status, predoctoral dental programs in the United States and Canada are required to train future dentists in the fundamentals of behavioral sciences. Each program independently determines how to fulfill this task, and little information exists on the consistency of training across programs. The purpose of this study was to identify the range of topics currently taught in predoctoral dental programs in the United States and Canada, who teaches them, and the modes of instruction and assessment.

Methods

Invitations to complete an online survey were emailed to faculty responsible for, or familiar with, the behavioral sciences curricula …

Immunohistochemical Analysis Of Dentigerous Cysts And Odontogenic Keratocysts Associated With Impacted Third Molars—A Systematic Review, Luis Eduardo Almeida, David Lloyd, Daniel Boettcher, Olivia Kraft, Samuel Zammuto

School of Dentistry Faculty Research and Publications

Objective: This systematic review investigates the diagnostic, prognostic, and therapeutic implications of immunohistochemical markers in dentigerous cysts (DCs) and odontogenic keratocysts (OKCs) associated with impacted third molars.

Materials and Methods: A comprehensive search strategy was employed across major databases including MEDLINE/PubMed, EMBASE, and Web of Science, from the inception of the databases to March 2024. Keywords and Medical Subject Heading (MeSH) terms such as “dentigerous cysts”, “odontogenic keratocysts”, “immunohistochemistry”, “Ki-67”, and “p53” were used. The PRISMA 2020 guidelines were followed to ensure methodological rigor. Inclusion criteria encompassed studies on humans and animals providing definitive diagnoses or specific signs and symptoms …

Evaluating Surgical Approaches For Hemimandibular Hyperplasia Associated With Osteochondroma: A Systematic Literature Review, Luis Eduardo Almeida, Samuel Zammuto, Diego Fernando Lopez

School of Dentistry Faculty Research and Publications

Background/Objectives: Hemimandibular hyperplasia (HH) associated with osteochondroma presents complex challenges in maxillofacial surgery, including facial asymmetry, occlusal instability, and temporomandibular joint (TMJ) dysfunction. Surgical interventions vary widely in approach and outcomes, underscoring the need for a systematic evaluation of effectiveness. This systematic review assesses the effectiveness of surgical approaches for managing HH associated with osteochondroma, focusing on techniques including condylectomy, orthognathic surgery, distraction osteogenesis, total joint replacement (TJR), and genioplasty. Methods: Following PRISMA 2020 guidelines, a comprehensive search was conducted in PubMed, Scopus, and Web of Science for studies published from 2000 to 2023. Eligibility criteria were based on the …

Bayesian Rare Variant Analysis Identifies Novel Schizophrenia Putative Risk Genes, Shengtong Han

School of Dentistry Faculty Research and Publications

The genetics of schizophrenia is so complex that it involves both common variants and rare variants. Rare variant association studies of schizophrenia are challenging because statistical methods for rare variant analysis are under-powered due to the rarity of rare variants. The recent Schizophrenia Exome meta-analysis (SCHEMA) consortium, the largest consortium in this field to date, has successfully identified 10 schizophrenia risk genes from ultra-rare variants by burden test, while more risk genes remain to be discovered by more powerful rare variant association test methods. In this study, we use a recently developed Bayesian rare variant association method that is powerful …

Association Between Periodontal Health Status And Quality Of Life: A Cross-Sectional Study, Kinan M. Al-Bitar, Jeffery M. Garcia, Shengtong Han, Arndt Guentsch

School of Dentistry Faculty Research and Publications

Introduction: Attachment loss due to periodontal diseases is associated with functional limitations as well as physical pain and psychological discomfort, which may lead to a reduced quality of life. The purpose of this study is to determine if the oral health status, specifically the periodontal status, influences oral health–related quality of life.

Materials and methods: Survey data were collected in a US dental school clinical setting in a cross-sectional study. Quality of life related to oral health was assessed with the Oral Health Impact Profile-49 (OHIP-49). In addition, DMFT index, periodontal status, and health literacy scores (dental and medical health …

Gastrointestinal Distress As A Potential Mediator Between Stress And Periodontal Inflammation, Casey D. Wright, Brenda Heaton, Raul I. Garcia, Maureen M. Leonard, Alessio Fasano, Daniel W. Mcneil

School of Dentistry Faculty Research and Publications

Objectives

Periodontal disease is multifactorial in its aetiology, which encompasses biopsychosocial contributors, including psychological stress. Gastrointestinal distress and dysbiosis have been associated with several chronic inflammatory diseases yet have rarely been investigated with respect to oral inflammation. Given the implications of gastrointestinal distress on extraintestinal inflammation, this study aimed to evaluate the potential role of such distress as a mediator between psychological stress and periodontal disease.

Methods

Utilizing a cross-sectional, nationwide sample of 828 adults in the USA generated via Amazon Mechanical Turk, we evaluated data collected from a series of validated self-report psychosocial questionnaires on stress, gut-specific anxiety around …

Detection Of Dental Restorations Using No-Code Artificial Intelligence, Manal Hamdan, Zaid Badr, Jennifer Bjork, Reagan Saxe, Francesca Malensek, Caroline Miller, Rakhi Shah, Shengtong Han, Hossein Mohammad-Rahimi

School of Dentistry Faculty Research and Publications

Objectives

The purpose of this study was to utilize a no-code computer vision platform to develop, train, and evaluate a model specifically designed for segmenting dental restorations on panoramic radiographs.

Methods

One hundred anonymized panoramic radiographs were selected for this study. Accurate labeling of dental restorations was performed by calibrated dental faculty and students, with subsequent final review by an oral radiologist. The radiographs were automatically split within the platform into training (70 %), development (20 %), and testing (10 %) subgroups. The model was trained for 40 epochs using a medium model size. Data augmentation techniques available within the …

Prevalence Of Temporomandibular Disorders (Tmd) In Obesity Patients: A Systematic Review And Meta-Analysis, Giuseppe Minervini, Rocco Franco, Maria Maddalena Marrapodi, Luis Eduardo Almeida, Vincenzo Ronsivalle, Marco Cicciù

School of Dentistry Faculty Research and Publications

Objective

Obesity is a growing epidemic in the world. It increases the risk for severe health conditions, including diabetes, heart disease and stroke. Recent research has found that obesity is associated with an increased risk for temporomandibular disorders (TMDs). The purpose of this literature review with meta-analysis is to analyse the possible association between obesity and temporomandibular disorders.

Materials and Methods

Pubmed, Web of Science and Lilacs were systematically searched until 01/03/2000. Articles dealing with TMD and obesity were selected, and numbers that might be useful in the meta-analysis were extracted.

Results

Fifty articles were chosen after using all three …

Temporomandibular Disorders And Physiotherapy, Luis Eduardo Almeida

School of Dentistry Faculty Research and Publications

No abstract provided.

Mandibular Condylar Hyperplasia And Its Correlation With Vascular Endothelial Growth Factor, Luis Eduardo Almeida, Marco Cicciù, Andrea Doetzer, Matthew L. Beck, Gabriele Cervino, Giuseppe Minervini

School of Dentistry Faculty Research and Publications

Background

Condylar hyperplasia (CH) is a rare condition characterised by excessive unilateral growth of the mandibular condyle after cessation of growth on the contralateral side causing facial asymmetry, being more prevalent in the second and third decades.

Objective

The aim of this study was to determine the utility of vascular endothelial growth factor (VEGF-A) as a diagnostic and prognostic factor in condylar hyperplasia, and to determine its potential viability as a therapeutic target.

Methods

This is a case–control study, where 17 mandibular condyles specimens were collected from 17 patients treated for active mandibular condyle hyperplasia and three unaffected human mandibular …

Patient-Reported Outcomes Following Guided Bone Regeneration: Correlation With Clinical Parameters, Vrisiis Kofina, Morvarid Monfaredzadeh, Swati Y. Rawal, Andrew R. Dentino, Maharaj Singh, Dimitris N. Tatakis

School of Dentistry Faculty Research and Publications

Objectives

Postoperative oral health-related quality of life is procedure-dependent and may vary during early healing. There is scarce evidence on patient-reported outcome measures (PROMs) after extraction and guided bone regeneration (GBR) or on the clinical parameters influencing PROMs. This prospective observational study aimed to evaluate PROMs during the first 2 weeks following extraction and GBR and correlate them with clinical parameters.

Methods

Patients undergoing extraction and GBR (bone graft and resorbable membrane) at a single tooth-bound site were recruited. PROMs (pain, swelling, difficulty of mouth opening, and OHIP-14) were recorded immediately preoperatively, and at 2, 7, and 14 days postoperatively. …

Sports Drinks Effect On Salivary Volume And Ph In Children After Exercise: A Randomized Clinical Study, Matina V. Angelopoulou, Alicia Malak-Santaga, Andreas Agouropoulos, Cesar D. Gonzalez

School of Dentistry Faculty Research and Publications

BACKGROUND: The aim of this study was to examine the sports’ related oral health behavior and the effect of sports drinks on the salivary volume and acidity of 6 to 14 years old children.

METHODS: Sixty-eight children with a median age of 8 years old from Waterford Tennis Association camp participated in the study. Each child was randomly assigned to either the control group that consumed water or the experimental group that consumed a sports drink. Salivary volume and acidity were measured for all groups before exercise, right after exercise and after consuming the rehydrating agent. Salivary volume was measured …

Vaccination Intention And Uptake Within The Black Community In Appalachia, Jamey T. Brumbaugh, Kalo C. Sokoto, Casey D. Wright, Sarah E. Francis, Jaliyah Hubbard, Linda Alexander, Daniel W. Mcneil

School of Dentistry Faculty Research and Publications

Objective:

Black communities have disproportionately experienced adverse health effects from the COVID-19 pandemic while simultaneously having less vaccination access and decreased vaccine utilization. As such, predictors of vaccination uptake within Black communities are a public health imperative. Black Americans from socio-geographic regions associated with health inequities (e.g., Appalachia), including vaccination disparities, represent an intersection of racial, economic, and ethnic social identities. To better understand the preventive health needs of Black communities in Appalachia and elsewhere, this study examined psychosocial predictors of vaccination intention or behavior.

Method:

Adults (n = 336) identifying as Black or African American from West …

An In-Vitro Analysis Of The Accuracy Of Different Guided Surgery Systems – They Are Not All The Same, Arndt Guentsch, Jennifer Bjork, Reagan Saxe, Shengtong Han, Andrew R. Dentino

School of Dentistry Faculty Research and Publications

Objectives

Different static computer-assisted implant surgery (sCAIS) systems are available that are based on different design concepts. The objective was to assess seven different systems in a controlled environment.

Materials and Methods

Each n = 20 implants were placed in identical mandible replicas (total n = 140). The systems utilized either drill-handles (group S and B), drill-body guidance (group Z and C), had the key attached to the drill (group D and V), or combined different design concepts (group N). The achieved final implant position was digitized utilizing cone-beam tomography and compared with the planned position. The angular deviation was …

Immunohistochemical Markers Of Temporomandibular Disorders: A Review Of The Literature, Luis Eduardo Almeida, Andrea Doetzer, Matthew L. Beck

School of Dentistry Faculty Research and Publications

Temporomandibular disorders (TMD) are a group of internal derangements encompassing dysfunction, displacement, degeneration of the temporomandibular joints and surroundings muscles of mastication, often accompanied by pain. Relationships between TMD and various chemical biomarkers have been examined throughout the years. This paper aims to gather evidence from the literature regarding other biomarkers and presenting them as one systematic review to investigate the potential links between TMD and different biochemical activity. To identify relevant papers, a comprehensive literature search was carried out in MEDLINE/PubMED, EMBASE, Web of Science and a manual search was performed in the International Journal of Oral and Maxillofacial …

Oral Care Among Older Adults In Assisted Living Facilities, Murad H. Taani, Christopher Okunseri, Kathryn L. Wagner

School of Dentistry Faculty Research and Publications

No abstract provided.

Intra-Marrow Penetrations And Root Coverage Outcomes: A Systematic Review, Vrisiis Kofina, Ving Wang, Alissa V. Fial, Dimitris N. Tatakis

School of Dentistry Faculty Research and Publications

Background

Intra-marrow penetrations (IMPs) have been performed during guided tissue regeneration (GTR) procedures with reported clinical benefits. The aim of this systematic review was to investigate the use and effect of IMPs during root coverage procedures.

Method

A broad search for human and animal studies was performed on PubMed, Cochrane Database of Systematic Reviews and Cochrane Central Registry of Controlled Trials and Web of Science, following a registered review protocol (PROSPERO). All prospective study designs, case series and case reports on gingival recession treatment (follow-up ≥ 6 months) that employed IMPs were included. Root coverage, complete root coverage prevalence, and …

Optimization Of The Modular Reinforced Bone Scaffold For Customized Alveolar Bone Defects, Meisam Omidi, Luis Eduardo Almeida, Lobat Tayebi

School of Dentistry Faculty Research and Publications

A modular reinforced bone scaffold with enhanced mechanical properties has recently been developed by our group. It includes: 1) A load-bearing module: a skeleton which is made of a slowly degradable material, undertaking mechanical necessities of the scaffold, and 2) A bio-reactive module: a porous and biodegradable component undertaking biological necessities of the scaffold. The load-bearing module is placed into the bio-reactive module to reinforce it. This paper is dedicated to optimizing the load-bearing module for a certain customized alveolar bone defect. More specifically, a 3D-printed skeleton, made of polycaprolactone (PCL), is optimized based on the boundary conditions of the …

Edge Chipping Of Translucent Zirconia, Joseph D. Flask, Geoffrey A. Thompson, Maharaj Singh, David W. Berzins

School of Dentistry Faculty Research and Publications

Statement of problem

More translucent dental zirconias have been developed by incorporating the cubic phase and reducing the tetragonal phase content that undergoes transformation toughening, leading to reduced mechanical properties. Whether the clinically relevant mechanical property of the edge chipping toughness of the material is also reduced is unclear.

Purpose

The purpose of this in vitro study was to evaluate the edge chipping toughness and translucency of translucent zirconia, 3mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP), and lithium disilicate.

Material and methods

Two translucent zirconia products, Katana and Lava Esthetic; one 3Y-TZP, Lava Plus; and one lithium disilicate, IPS e.max Press …

P53 And Vegf Expression In Human Temporomandibular Joint Discs With Internal Derangement Correlate With Degeneration, Sergio Castorina, C. Lombardo, Paola Castrogiovanni, Giuseppe Musumeci, E. Barbato, Luis Eduardo Almeida, Rosalia Leonardi

School of Dentistry Faculty Research and Publications

No abstract provided.