Dentistry Commons^™

Prevalence Of Molar-Incisor Hypomineralization In Milwaukee, Wisconsin, Usa: A Pilot Study, Megan Davenport, Andrew D. Welles, Matina V. Angelopoulou, Cesar D. Gonzalez, Christopher Okunseri, Lori Barbeau, Naveen K. Bansal, Rodney Vergotine, Brian D. Hodgson

School of Dentistry Faculty Research and Publications

Purpose: This pilot study investigated the prevalence of Molar-Incisor Hypomineralization (MIH) in third-grade school children in Milwaukee Wisconsin, USA.

Methods: A convenience sample of third-grade school children in the Milwaukee Public School System (MPS) participated in the study. Calibrated examiners trained on the European Academy of Paediatric Dentistry (EAPD) MIH recommendations examined the children between December 1, 2014 and June 30, 2015. Children were examined at their schools using a flashlight and mirror after receiving consent from parents/caregivers and assent from each child. Findings were recorded onto a standardized form by one of five trained examiners. Summary statistics were calculated, …

The Design And Physical Properties Of An Optimized Chitosan Hydrogel For Potential Use In Endodontics, Hunter Housley

Master's Theses (2009 -)

Introduction: The aim of this study was to synthesize an optimized chitosan/carbon dot hydrogel and measure its effects on the proliferation of dental pulp stem cells. Methods: 1.5% w/v chitosan hydrogel samples were fabricated with 300 mg/ml aqueous β-glycerol phosphate (β-GP) to create an optimized chitosan with a gelation onset temperature below 37°C. Spermidine-functionalized carbon dots (CDs) were added to test groups in concentrations of 25 µg/ml and 50 µg/ml. Complex shear viscosity of the prepared hydrogel samples was evaluated with a Kinexus pro+ shear rheometer (Malvern Panalytical). Samples were evaluated for cellular proliferation with dental pulp stem cells at …

The Influence Of Full Coverage Restorations On Pulp Vitality: A Ten-Year Retrospective Study, Abby Yavorek

Master's Theses (2009 -)

INTRODUCTION: The incidence of pulpal disease after delivery of a full-coverage crown has been previously described as between 2-19%. The objective of this study was to identify and analyze the factors that contribute to the incidence of NS-RCT after the delivery of single-unit full-coverage restorations. MATERIALS AND METHODS: Insurance claims from 88,409 crown placements in the Delta Dental of Wisconsin Insurance database were analyzed from the years 2008 to 2017. The Cox Regression model was used to analyze the effect of the predictor variables on the survival of the tooth. Untoward events were defined as NS-RCT, tooth extraction, retreatment of …

Comparison Of Power Versus Manual Toothbrush In Reducing Gingivitis, Keerthi Kamreddy

Master's Theses (2009 -)

The purpose of the present 4-week, parallel-arm, single-blinded, clinical study is to investigate the efficacy and safety of a new power toothbrush in comparison with a standard flat trim ADA approved manual brush. The primary objective of this study is to evaluate the efficacy of powered toothbrush on gingivitis reduction compared to a manual toothbrush. Secondary objectives of this study are to evaluate the effectiveness of plaque removal.Materials & Methods: The study was a single-blinded parallel arm randomized controlled interventional trial. Forty-six male and female subjects with gingivitis (32 female and 16 males) with a mean age of 26 …

Injectable Gels With Potential Use In Endodontics, Maksim Montatskiy

Master's Theses (2009 -)

Objective: To formulate a thermoreversible hydrogel using methyl-cellulose, carbon dots and inorganic salts to achieve physiologically compatible gelation temperature; to test cytotoxic effects of formulation against dental pulp stem cells.Materials/Methods: A 5% w/v methylcellulose (MC) solution was prepared and equal volumes of NaCl aqueous solution were added to make various sodium chloride salt concentrations and reach the final MC concentration of 2.5%. Samples were analyzed using a shear rheometer to monitor complex shear viscosity as a function of temperature to arrive at onset gelation temperature closest to targeted temperature. Carbon dots were synthesized by thermal method using ammonium citrate …

An In Vitro Study Of Surface Alterations To Peek And Titanium And Its Effect Upon Human Gingival Fibroblasts, Maryam Gheisarifar

Master's Theses (2009 -)

Objective: Soft tissue attachment to different surfaces plays a pivotal role in long term success of dental implants. The aim of the current study was to evaluate viability and adhestion of human gingival fibroblasts (HGFs) upon specific surface modifications on different implant abutment materials. Material & Methods: A total of 150 specimens in 6 experimental groups were used: titanium alloy (Ti [smooth machined]), titanium laser-modified (TiL), PEEK (P [smooth machined]), PEEK laser-modified (PL), PEEK plasma treated (PP), PEEK laser and Plasma treated (PLP). The surface roughness (Sa), water contact angle (WCA), and X-ray photoelectron spectroscopy (XPS) were measured. Human gingival …

Effect Of Different Implant Abutment Materials On Optical Properties Of Translucent Monolithic Zirconia Crowns, Nisha Patel

Master's Theses (2009 -)

Purpose: The purpose of this study was to evaluate the effect of implant abutment color on the final shade of monolithic translucent zirconia crowns. The null hypothesis was that abutment color or brand of zirconia would have no effect on color of monolithic translucent zirconia crowns.Material and methods: A maxillary right central incisor implant (Nobel Replace Trilobe RP) in a dentoform model was used to mill customized abutments of titanium, gold-anodized titanium, pink-anodized titanium, and zirconium dioxide. An A2 dentin shade polymethyl methacrylate abutment was used as a control. Four types of zirconia systems (BruxZir Anterior; Glidewell Laboratories, LAVA …

Evaluation Of Accuracy Of Static Computer-Guided Implant Placement Compared With Partially-Guided Or Free-Hand Placement, Laxmi Sukhtankar

Master's Theses (2009 -)

Purpose: To evaluate precision and trueness of static computer-assisted implant surgery (sCAIS) in comparison with partially-guided and free-hand implant placement in vitro.Materials & Methods: The study was conducted on one hundred mandible replicas obtained from a cone beam computer tomography of a partially edentulous case for implant placement in mandibular right first molar site. First, the fully guided implant placement with different sleeve to bone distances (2mm = H2, 4mm = H4, 6mm= H6) was determined. Second, fully guided implant placement was compared with partially guided, and free implant placement. The achieved implant position was digitized and compared …

Association Of Food Insecurity With Early Childhood Caries, Matina V. Angelopoulou, S. D. Shanti, Cesar D. Gonzalez, Ashley Love, Jeffrey Chaffin

School of Dentistry Faculty Research and Publications

Objectives

The aim of this study was to examine the association of food insecurity on the prevalence of dental caries in preschool children.

Methods

Eighty-two children, aged 12-71 months old, from the Marquette University School of Dentistry Community South Clinic and their caregivers participated in this cross-sectional study. Following informed consent, parents completed the validated six-item US Department of Agriculture food insecurity questionnaire and questions regarding demographic information and family structure. Upon clinical examination caries was recorded using the decayed, missing, filled teeth (dmft) index based on the International Caries Detection and Assessment System criteria.

Results

The correlation between dmft …

The Effectiveness Of Different Attachment Systems Maxillary And Mandibular Implant Overdentures, Gary L. Stafford

School of Dentistry Faculty Research and Publications

Data sources Cochrane Oral Health's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, the US National Institutes of Health Ongoing Trials Register (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform.

Study selection Randomised controlled trials (RCTs), including cross-over trials on maxillary or mandibular implant overdentures with different attachment systems with at least one-year follow-up were considered. There were no restrictions on language or date of publication.

Data extraction and synthesis Data were abstracted by four reviewers with risk of bias being assessed using the Cochrane tool. Data were combined using a fixed effects …

Primary Molar Pulpotomies With Different Hemorrhage Control Agents And Base Materials: A Randomized Clinical Trial, G. Atasever, T. I. Keceli, Serdar Uysal, H. Cem Güngör, S. Olmez

School of Dentistry Faculty Research and Publications

Objective: To evaluate the clinical and radiographical success of primary molar pulpotomies which used 15.5% ferric sulfate (FS) or 1.25% sodium hypochlorite (NaOCl) for hemostasis and zinc oxide-eugenol (ZOE) and calcium hydroxide (CH) pastes as base materials.

Methods: In 29 healthy children, 80 primary molars were randomly allocated to one of the study groups: Group 1: FS-ZOE, Group 2: FS-CH, Group 3: NaOCl-ZOE, and Group 4: NaOCl-CH. After hemostasis with the respective solutions, pulp stumps and floor of the pulp chambers were covered with either ZOE or CH pastes. All teeth were restored with stainless steel crowns. Follow-up examinations were …

Effect Of Airborne-Particle Abrasion On 3-Dimensional Surface Roughness And Characteristic Failure Load Of Fiber-Reinforced Posts, Georgios Maroulakos, Michael W. Wanserski, Michelle M. Wanserski, Ethan J. Schuler, Colin P. Egan, Geoffrey A. Thompson

School of Dentistry Faculty Research and Publications

Statement of problem

Debonding is the most common complication of fiber-reinforced posts (FRPs). Airborne-particle abrasion (APA) has been suggested to increase resin cement adhesion to the surface of FRPs. However, which abrasion protocol is the most favorable is unclear.

Purpose

The purpose of this in vitro study was to compare the surface roughness and characteristic failure load of three FRP systems following different APA protocols.

Material and methods

A total of 150 posts from 3 manufacturers (glass FRP, quartz FRP, and zirconia-enriched glass FRP) were randomly assigned to different surface treatments (NT: no treatment—control; E0: cleaned with 96% ethanol solution; …

Mathematical Modeling Of Oxygen Transfer In Porous Scaffolds For Stem Cell Growth: The Effects Of Porosity, Cell Type, Scaffold Architecture And Cell Distribution, Saeid Atashrouz, Ali Hatampoor, Amir Yadegari, Hamed Ghasemi, Lobat Tayebi, Morteza Rasoulianboroujeni

School of Dentistry Faculty Research and Publications

Oxygen plays a key role in human mesenchymal stem cell growth. Without adequate oxygen (hypoxic condition), cells are not able to survive, proliferate, and migrate. The objective of the present study is to investigate oxygen transfer through the cell-seeded scaffolds stored in static or dynamic bioreactors using a mathematical model. The effects of porosity, cell type, scaffold architecture and cell distribution as potential effective parameters on oxygen transfer kinetics were examined. The results suggest the substantial effect of porosity and cell type on the oxygen concentration within the scaffold compared to scaffold architecture (homogeneous vs. gradient). The obtained data …

Culture Of Dental Pulp Stem Cells On Nanoporous Alumina Substrates Modified By Carbon Nanotubes, Ameneh Alizadeh, Amir Razmjou, Mehrorang Ghaedi, Ramin Jannesar, Fahimeh Tabatabaei, Vahid Pezeshkpour, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose: Alumina substrates are one of the commonly used scaffolds applied in cell culture, but in order to prevent formation of biofilm on the alumina substrate, these substrates are modified with carbon nanotube. Methods: The alumina substrate was made by a two-step anodization method and was then modified with carbon nanotubes by simple chemical reaction. The substrates were characterized with FTIR, SEM, EDX, 3D laser scanning digital microscope, contact angle (CA) and surface free energy (SFE). To determine how this modification influences the reduction of biofilm, biofilm of two various bacteria, Escherichia coli (E.coli) and Staphylococcus aureus ( …

Edta-Modified Mesoporous Silica As Supra Absorbent Of Copper Ions With Novel Approach As An Antidote Agent In Copper Toxicity, Elham Rafiee Taqanaki, Reza Heidari, Mohammad Monfared, Lobat Tayebi, Amir Azadi, Fatemeh Farjadian

School of Dentistry Faculty Research and Publications

Purpose: Mesoporous silica (MS) have been considered as a biocompatible compound and found to have various pharmaceutical applications. Recently, novel approaches in applications of MS as antidote agents were introduced. In this study, the capacity of ethylenediaminetetraacetic acid modified mesoporous silica (MS-EDTA) was evaluated in in vitro and in vivo adsorption of copper (Cu). Methods: The MS-EDTA was characterized by fourier transform infrared (FT-IR) and X-ray diffraction, while surface area was determined by N₂ adsorption–desorption technique. Morphological studies were observed by high resolution-transmission electron microscopy and field emission-scanning electron microscopy and the sizes were determined by dynamic light scattering. …

Influence Of Apical Preparation Size On Effective Conventional Irrigation In The Apical Third: A Scanning Electron Microscopic Study, Seth Butcher, Abeer Mansour, Mohamed Ibrahim

School of Dentistry Faculty Research and Publications

Objective: This study aimed to investigate the relationship between final apical preparation size and smear layer removal in the apical third using conventional irrigation in mandibular bicuspids.

Methods: A total of 66 extracted human mandibular bicuspids with comparable root canal morphology were equally divided into five experimental groups and a control group (n=11). Based on their experimental group, samples were instrumented up to size 25, 30, 35, 40, or 45 with 0.04 taper using 2.5% sodium hypochlorite (NaOCl) as the irrigant. Final irrigation was performed with 17% EDTA followed by 2.5% NaOCl. The control group was instrumented up to size …

Early Condylectomy: Biological Considerations, Diego Fernando López, Juliana Ruiz Botero, Luis Eduardo Almeida

School of Dentistry Faculty Research and Publications

Objective: To describe the early treatment of two patients with unilateral condylar hyperplasia (UCH) diagnosis and therapeutic surgical protocol (early condylectomy) supported by the current biological knowledge about the development and repair of mandibular condyle cartilage (MCC). Methods: Review of the literature and two case description of the treatment. The two patients were girls, 12 and 13 year old. The follow up period was of 3 years. SPECT diagnostic, radiographic, photographic and tomographic images are presented. Results: The literature summarized provides biological basis favoring the early treatment of UCH. The two cases were treated with the same surgical protocol obtaining …

Applications Of 3d Printing On Craniofacial Bone Repair: A Systematic Review, Michael Maroulakos, George Kamperos, Lobat Tayebi, Demetrios J. Halazonetis, Yijin Ren

School of Dentistry Faculty Research and Publications

Objectives

Three-dimensional (3D) bioprinting, a method derived from additive manufacturing technology, is a recent and ongoing trend for the construction of 3D volumetric structures. The purpose of this systematic review is to summarize evidence from existing human and animal studies assessing the application of 3D printing on bone repair and regeneration in the craniofacial region.

Data & sources

A rigorous search of all relevant clinical trials and case series was performed, based on specific inclusion and exclusion criteria. The search was conducted in all available electronic databases and sources, supplemented by a manual search, in December 2017.

Study selection

43 …

Ankylosing Spondylitis And Mesenchymal Stromal/Stem Cell Therapy: A New Therapeutic Approach, Kamal Abdolmohammadi, Fatemeh Dadgar Pakdel, Hamideh Aghaei, Sara Assadiasl, Yousef Fatahi, Negin Hosseini Rouzbahani, Alireza Rezaiemanesh, Masoud Soleimani, Lobat Tayebi, Mohammad Hossein Nicknam

School of Dentistry Faculty Research and Publications

Ankylosing spondylitis (AS) is an inflammatory rheumatoid disease categorized within spondyloarthropathies (SpA) and manifested by chronic spinal arthritis. Several innate and adaptive immune cells and secreted-mediators have been indicated to play a role in AS pathogenesis. Considering the limitations of current therapeutic approaches (NSAIDs, glucocorticoids, DMARDs and biologic drugs), finding new treatments with fewer side effects and high therapeutic potentials are required in AS. Mesenchymal stem cells (MSCs) with considerable immunomodulatory and regenerative properties could be able to attenuate the inflammatory responses and help tissue repair by cell-to-cell contact and secretion of soluble factors. Moreover, MSCs do not express HLA-DR, …

Biomaterials Evaluation: Conceptual Refinements And Practical Reforms, Reza Masaeli, Kavosh Zandsalimi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Regarding the widespread and ever-increasing applications of biomaterials in different medical fields, their accurate assessment is of great importance. Hence the safety and efficacy of biomaterials is confirmed only through the evaluation process, the way it is done has direct effects on public health. Although every biomaterial undergoes rigorous premarket evaluation, the regulatory agencies receive a considerable number of complications and adverse event reports annually. The main factors that challenge the process of biomaterials evaluation are dissimilar regulations, asynchrony of biomaterials evaluation and biomaterials development, inherent biases of postmarketing data, and cost and timing issues. Several pieces of evidence indicate …

Microfluidic Synthesis Of Plga/Carbon Quantum Dot Microspheres For Vascular Endothelial Growth Factor Delivery, Meisam Omidi, Mohadeseh Hashemi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

In this study, vascular endothelial growth factor (VEGF) loaded poly(D,L-lactide-co-glycolide) (PLGA) – carbon quantum dot microspheres were produced using microfluidic platforms. The microcapsules were fabricated in flow-focusing geometry with a biphasic flow to generate solid/oil/water (s–o–w) droplets. To avoid any damage to protein functional and structural stability during the encapsulation process, the VEGF was PEGylated. The produced microspheres were intact and highly monodisperse in size (CV < 5%). Furthermore, microspheres in a size range of 16–36 µm were achieved by adjusting the flow ratio parameter. The encapsulation efficiency, release profile, and bioactivity of the produced microparticles were also studied. The loading efficiency of PEGylated VEGF in the microparticles was varied from 51–69% and more than 90% of PEGylated VEGF was released within 28 days. Furthermore, the release of VEGF was indirectly monitored by carbon quantum dots. The present monodisperse and controllable VEGF loaded microspheres with reproducible manner could be widely used in tissue engineering and therapeutic applications.

Applications Of 3d Printing On Craniofacial Bone Repair, Michael Maroulakos, George Kamperos, Lobat Tayebi, Demetrios J. Halazonetis, Yijin Ren

School of Dentistry Faculty Research and Publications

Objectives

Three-dimensional (3D) bioprinting, a method derived from additive manufacturing technology, is a recent and ongoing trend for the construction of 3D volumetric structures. The purpose of this systematic review is to summarize evidence from existing human and animal studies assessing the application of 3D printing on bone repair and regeneration in the craniofacial region.

Data & sources

A rigorous search of all relevant clinical trials and case series was performed, based on specific inclusion and exclusion criteria. The search was conducted in all available electronic databases and sources, supplemented by a manual search, in December 2017.

Study selection

43 …

Adenosquamous Carcinoma Of The Tongue, Yeshwant B. Rawal, Kenneth M. Anderson

School of Dentistry Faculty Research and Publications

A 51-year-old white female presented with a painful ulcer of the left ventrolateral tongue. An incisional biopsy confirmed a diagnosis of adenosquamous carcinoma. The adenosquamous carcinoma is an uncommon malignant tumor with histopathological features of a squamous carcinoma and an adenocarcinoma. A definitive diagnosis requires histopathological examination of a deep biopsy involving the submucosal tissue. This malignant tumor shows aggressive behavior with early invasive growth and a poor prognosis. The histopathological findings and differential diagnosis of a case of adenosquamous carcinoma of the tongue are discussed.

Impending Total Airway Collapse Involving A Maxillary Removable Partial Denture: A Clinical Report, Georgios Maroulakos, Stylianos Voulgarelis

School of Dentistry Faculty Research and Publications

This article presents a rare incident of a bilateral maxillary removable partial denture as an airway foreign body. The removable partial denture and the surrounding soft tissue irritation caused partial obstruction of the airway. Impending airway collapse was avoided after successful removal of the foreign body. Removing a removable dental prostheses at night, not only to prevent soft tissue pathology but also to avoid ingestion or aspiration of the prosthesis, must be emphasized.

Using Enamel Matrix Derivative To Improve Treatment Efficacy In Periodontal Furcation Defects, Reza Masaeli, Kavosh Zandsalimi, Zahra Lotfi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding furcation‐affected teeth. These biomaterials range from bone grafts and nonresorbable/resorbable barrier membranes to biologics that are able to trigger inactive regenerative processes in periodontal tissues. Selection of appropriate material(s) to treat furcations is challenging. The aim of this article is to provide a comparative outlook on different biomaterials applicable in regeneration of furcations with a focus on enamel matrix derivative (EMD).

Methods

Scientific databases including PubMed/MEDLINE, ScienceDirect, …

Management Of Cervical Root Fracture Injury In A Patient With Epilepsy: Case Report With 5-Year Follow-Up, Elif Ataol, Gizem Erbaş Ünverdi, H. Cem Güngör

School of Dentistry Faculty Research and Publications

The difficulty in providing stability to the coronal segment makes cervical root fracture one of the most challenging dental traumatic injury. This type of injury is less frequent in children. However, due to their serious consequences and poor prognosis, tooth loss may occur. This report presents the management of a case of cervical root fracture in an 11-year-old patient with epilepsy. The stabilization of the root-fractured tooth with a splint failed due to the recurrent seizures the patient had. Coronal fragment was removed and vital root submergence was performed in order to support the alveolar growth. The natural tooth crown …

In Vitro Effect Of Graphene Structures As An Osteoinductive Factor In Bone Tissue Engineering: A Systematic Review, Dorsa Mohammadrezaei, Hossein Golzar, Maryam Rezai Rad, Meisam Omidi, Hamid Rashedi, Fatemeh Yazdian, Arash Khojasteh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Graphene and its derivatives have been well‐known as influential factors in differentiating stem/progenitor cells toward the osteoblastic lineage. However, there have been many controversies in the literature regarding the parameters effect on bone regeneration, including graphene concentration, size, type, dimension, hydrophilicity, functionalization, and composition. This study attempts to produce a comprehensive review regarding the given parameters and their effects on stimulating cell behaviors such as proliferation, viability, attachment and osteogenic differentiation. In this study, a systematic search of MEDLINE database was conducted for in vitro studies on the use of graphene and its derivatives for bone tissue engineering from January …

In Reply, Yeshwant B. Rawal, Joshua S. Brandner, Louis J. Kim, Jasjit K. Dillon

School of Dentistry Faculty Research and Publications

No abstract provided.

Orthodontic Treatment Planning Using Direct Visual Approximation Of Arch Length Discrepancy And Cephalometric Analyses, Kathleen Rouse Vaught

Master's Theses (2009 -)

Introduction: Space analysis and radiographic analyses are crucial elements in developing an orthodontic treatment plan. It is imperative that the orthodontist makes accurate measurements in order to come up with the most effective treatment options for each patient. Some practitioners refrain from direct measurements to determine arch length discrepancies and instead determine the amount of crowding by using direct visual approximation. In addition, more orthodontists do not routinely trace all cephalograms taken. If more and more orthodontists are using direct visual approximation to determine angular cephalometric measurements, it is important to assess the accuracy and reliability of these measurements. This …

Comparison Of Immediate Vs. Delayed Recall Of Orthodontic Information Following An Electronic Reminder, Michael Lenz

Master's Theses (2009 -)

Patients and parents in dentistry often do not remember important information disclosed during the informed consent process, so improvement in the delivery of information is needed. This study explored the effect of an emailed narrated instructional PowerPoint on the immediate vs. delayed recall and comprehension of informed consent information in orthodontics. Thirty-two subjects were recruited from a university and private practice orthodontic clinic. At the initial visit, subjects were alternately assigned to one of two groups and were presented with a mock orthodontic treatment plan and informed consent presentation for a pretend patient. Immediately following the presentation, the subjects’ verbal …