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Articles 61 - 90 of 259
Full-Text Articles in Communication Sciences and Disorders
Duration Of Time Spent Playing Online Video Games, Interpersonal Skills, And Introversion Personality Traits As Predictors For Social Anxiety Symptoms, James D. Bender
Duration Of Time Spent Playing Online Video Games, Interpersonal Skills, And Introversion Personality Traits As Predictors For Social Anxiety Symptoms, James D. Bender
Masters Theses & Specialist Projects
This study sought to determine if time spent engaging in online gaming, interpersonal communication skills, and introvert personality traits are predictors of an individual’s likelihood of experiencing symptoms of social anxiety. A sample of 128 participants (82 males and 46 females) completed measures of demographics, interpersonal communication skills, problematic online gaming, social anxiety, and introversion. Participants were recruited through Amazon Mechanical Turk. There were significant correlations among social anxiety and interpersonal communication skills, problematic online gaming, and introversion. There was no significant correlation among social anxiety and time spent playing Massively Multiplayer Online Role-Playing Games (MMORPG), a specific form of …
Large Cross-Sectional Study Of Presbycusis Reveals Rapid Progressive Decline In Auditory Temporal Acuity, Erol J. Ozmeral, Ann C. Eddins, Robert Frisina Sr., David A. Eddins
Large Cross-Sectional Study Of Presbycusis Reveals Rapid Progressive Decline In Auditory Temporal Acuity, Erol J. Ozmeral, Ann C. Eddins, Robert Frisina Sr., David A. Eddins
Communication Sciences and Disorders Faculty Publications
The auditory system relies on extraordinarily precise timing cues for the accurate perception of speech, music, and object identification. Epidemiological research has documented the age-related progressive decline in hearing sensitivity that is known to be a major health concern for the elderly. Although smaller investigations indicate that auditory temporal processing also declines with age, such measures have not been included in larger studies. Temporal gap detection thresholds (TGDTs; an index of auditory temporal resolution) measured in 1071 listeners (aged 18–98 years) were shown to decline at a minimum rate of 1.05 ms (15%) per decade. Age was a significant predictor …
Story Retell Narratives In Five School-Aged Children With Language Impairment, Megan Bradshaw Deere
Story Retell Narratives In Five School-Aged Children With Language Impairment, Megan Bradshaw Deere
Theses and Dissertations
Many children identified with Language Impairment (LI) demonstrate difficulty comprehending and producing narratives. Their narratives are often structurally less complex and of overall poorer quality than those produced by their typically developing peers. These difficulties may negatively impact the academic and social success of children with LI. This thesis evaluates the performance of five school-aged children with LI on a story retell probe embedded within an intervention designed to address their social and emotional language abilities. During the 10-week intervention, participants completed a series of story retell probes using wordless picture books. The story stimuli were taken from the Edmonton …
Sleep Deprivation And Recovery: The Effects Of P300 Three And Six Hours Post Recovery, Kimberly A. Brauer
Sleep Deprivation And Recovery: The Effects Of P300 Three And Six Hours Post Recovery, Kimberly A. Brauer
Graduate Theses/Dissertations
The P300 waveform is an auditory evoked potential (AEP) elicited through a decision making process. Due to the endogenous nature of the P300 response, which requires participants to actively respond to an auditory stimuli, it has been used as on objective measure to evaluate the cognitive processes of attention and memory. Previous studies have looked at the P300 before and after sleep deprivation as well as after brief rest periods. Evidence shows that a decline in P300 amplitudes and increase in latency are seen after 24 hours of sleep deprivation and improvements in the P300 are seen after a recovery …
Rubrics: Effectiveness Of Feedback, Sadie Louise Winterscheid
Rubrics: Effectiveness Of Feedback, Sadie Louise Winterscheid
Graduate Theses/Dissertations
The purpose of this study was to determine how rubrics affect university graduate students' receptiveness to feedback, their future college assignments, and if they will use rubrics in their own classroom. Two surveys were sent to teachers and teacher candidate graduate students from a Midwestern university. Participants were asked to answer one of the two surveys depending on whether they had their teaching certificate or were working to receive their teaching certificate. The participants answered survey questions about their college experience with rubrics and their experience and opinions of rubrics in their own, or future, classrooms. The research demonstrated that: …
Construction And Evaluation Of Rodent-Specific Rtms Coils, Alexander D. Tang, Andrea S. Lowe, Andrew R. Garrett, Robert Woodward, William Bennett, Alison J. Canty, Michael I. Garry, Mark R. Hinder, Jeffery J. Summers, Roman Gersner, Alexander Rotenberg, Gary Thickbroom, Joseph P. Walton, Jennifer Rodger
Construction And Evaluation Of Rodent-Specific Rtms Coils, Alexander D. Tang, Andrea S. Lowe, Andrew R. Garrett, Robert Woodward, William Bennett, Alison J. Canty, Michael I. Garry, Mark R. Hinder, Jeffery J. Summers, Roman Gersner, Alexander Rotenberg, Gary Thickbroom, Joseph P. Walton, Jennifer Rodger
Communication Sciences and Disorders Faculty Publications
Rodent models of transcranial magnetic stimulation (TMS) play a crucial role in aiding the understanding of the cellular and molecular mechanisms underlying TMS induced plasticity. Rodent-specific TMS have previously been used to deliver focal stimulation at the cost of stimulus intensity (12 mT). Here we describe two novel TMS coils designed to deliver repetitive TMS (rTMS) at greater stimulation intensities whilst maintaining spatial resolution. Two circular coils (8 mm outer diameter) were constructed with either an air or pure iron-core. Peak magnetic field strength for the air and iron-cores were 90 and 120 mT, respectively, with the iron-core coil exhibiting …
Static And Dynamic Spectral Acuity In Cochlear Implant Listeners For Simple And Speech-Like Stimuli, Benjamin Anderson Russell
Static And Dynamic Spectral Acuity In Cochlear Implant Listeners For Simple And Speech-Like Stimuli, Benjamin Anderson Russell
USF Tampa Graduate Theses and Dissertations
For cochlear implant (CI) listeners, poorer than normal speech recognition abilities are typically attributed to degraded spectral acuity. However, estimates of spectral acuity have most often been obtained using simple (tonal) stimuli, presented directly to the implanted electrodes, rather than through the speech processor as occurs in everyday listening. Further, little is known about spectral acuity for dynamic stimuli, as compared to static stimuli, even though the perception of dynamic spectral cues is important for speech perception.
The primary goal of the current study was to examine spectral acuity in CI listeners, and a comparison group of normal hearing (NH) …
Interspeech Posture In Spanish-English Bilingual Adults, Merrily Rose Shary
Interspeech Posture In Spanish-English Bilingual Adults, Merrily Rose Shary
USF Tampa Graduate Theses and Dissertations
Interspeech posture (ISP) is a term used to define the position of a person’s articulators when they are preparing to speak. Research suggests that ISP may be representative of a speaker’s phonological knowledge in a particular language, as determined empirically with ultrasound measures of the tongue in English-French bilinguals (Wilson & Gick, 2014). It is possible, therefore, that measuring ISP could be a diagnostic tool for determining phonological knowledge in bilingual speakers. However, more information on ISP in typical adult bilingual speakers is needed before diagnostic claims can be made. For example, ISP is believed to be language specific, and …
Effects Of A Novel Right Brain Intervention On Stuttering Frequency In Unfamiliar Speech Tasks, Chelsea Beatrice Stewart
Effects Of A Novel Right Brain Intervention On Stuttering Frequency In Unfamiliar Speech Tasks, Chelsea Beatrice Stewart
USF Tampa Graduate Theses and Dissertations
Developmental stuttering persists in approximately 1% of the United States population. Stuttering has been shown to impact overall quality of life. The present study examines the effects of a Novel Right Brain Intervention on two female participants with persistent developmental stuttering. The aim of the study was to determine whether encouraging greater activation of the right hemisphere, specifically the pre-SMA, via complex left-handed movements, prior to speech production, would lead to a reduced stuttering frequency and severity in people who stutter (PWS). It was hypothesized that each participant would reduce stuttering symptoms and behaviors following the intervention due to the …
Analysis Of Patterns In Handwritten Spelling Errors Among Students With Various Specific Learning Disabilities, Laura Ann Winkler
Analysis Of Patterns In Handwritten Spelling Errors Among Students With Various Specific Learning Disabilities, Laura Ann Winkler
USF Tampa Graduate Theses and Dissertations
Students diagnosed with specific learning disabilities struggle with spelling accuracy, but they do so for different reasons. For instance, students with dysgraphia, dyslexia, and oral-written language learning disability (OWL-LD) have distinct areas of weakness in cognitive processing and unique difficulties with the linguistic features necessary for accurate spelling (Silliman & Berninger, 2011). This project considered the spelling errors made by such students to determine if their unique learning profiles lead to distinct misspelling patterns.
Academic summaries handwritten by 33 students diagnosed with dysgraphia (n=13), dyslexia (n=15), and OWL-LD (n=5) were analyzed for type/complexity and …
Effects Of A Novel Right Brain Intervention On Stuttering In Familiar And Structured Speech Tasks, Josalyn Elizabeth Perry
Effects Of A Novel Right Brain Intervention On Stuttering In Familiar And Structured Speech Tasks, Josalyn Elizabeth Perry
USF Tampa Graduate Theses and Dissertations
Over 3 million Americans are disfluent due to developmental stuttering. Current evidence-based treatments typically consist of a rigorous schedule of intensive therapy, followed by the need for maintenance of skills, placing high demands on self-monitoring of one’s speech at all times. Relapse after treatment is very common, at 84%. The demand for further research into treatment possibilities for stuttering is on the forefront. Previous research has connected neural activations in people who stutter (PWS) and people with chronic nonfluent aphasia. The aim of this study was to determine if a novel intervention, based on a treatment for anomia, would change …
Tongue Twisters Quantified: Ultrasound Analysis Of Speech Stability And Speech Errors, Karen Reddick
Tongue Twisters Quantified: Ultrasound Analysis Of Speech Stability And Speech Errors, Karen Reddick
USF Tampa Graduate Theses and Dissertations
This thesis investigates errors on speech sounds (or phonemes) produced in laboratory speech stimuli designed to generate phonological onset errors. The present study adds to the literature on phonological speech errors with an instrumental analysis of tongue posture during speech error production and an investigation of the nature of speech errors as unintended variation in articulation.
This study utilized ultrasound instrumentation to visualize speech errors made on velar and alveolar stop consonants at the point of stop closure. Two types of errors were of interest, categorical errors and gradient errors. Categorical errors are those that are heard by the listener …
Assessing Excessive Noise Exposure Of Music-Oriented Nightclub Employees, Aiyanna Fitzgerald
Assessing Excessive Noise Exposure Of Music-Oriented Nightclub Employees, Aiyanna Fitzgerald
USF Tampa Graduate Theses and Dissertations
Much research has gone into noise-induced hearing loss (NIHL) and the effects of high intensity noise levels on the hearing mechanism of individuals. A study by the National Institutes of Health has established that high intensity sounds can cause hearing damage of either a temporary, or worse, a permanent nature; regardless of the age of the person. While sound levels below 75 decibels are considered comparatively harmless and have been found not to cause any kind of permanent hearing loss; sound levels greater than 85 decibels and regular exposure of approximately 8 hours per day, on an average, has been …
Hearing Aid Use And Cognitive Function: A Systematic Review, Hershel Korngut
Hearing Aid Use And Cognitive Function: A Systematic Review, Hershel Korngut
Dissertations, Theses, and Capstone Projects
This systematic review analyzed the research relating the use of hearing aids to cognitive function. Hearing aid use was examined to see if wearing hearing aids improves cognitive function, if the length of time hearing aids are worn impacts cognitive ability, if the type of hearing aid used has any impact on cognitive function, and if hearing aid use slows down cognitive decline. Ten studies met the criteria for this review. An analysis of the research revealed some evidence to support wearing hearing aids improves cognitive function, however, there is substantial evidence that shows no impact between wearing hearing aids …
Development Of A Patient-Centered Health Literacy Toolkit For Audiology And Hearing Loss (The 'Hh Lit Kit'), Jennifer L. Gilligan
Development Of A Patient-Centered Health Literacy Toolkit For Audiology And Hearing Loss (The 'Hh Lit Kit'), Jennifer L. Gilligan
Dissertations, Theses, and Capstone Projects
The Patient-Centered Health Literacy Toolkit for Audiology & Hearing Loss (‘HH Lit Kit’) represents four years of inquiry into health literacy and Patient-Centered Care (PCC) in audiology. While awareness of health literacy continues to gain momentum in medicine and public health, there is a paucity of information on PCC and health literacy in audiology.
Low health literacy is linked to poorer health and poorer quality of life. Patients with hearing loss are at high risk for low health literacy. This presents a major concern because hearing loss affects the way information is processed, retained, and applied. Gaps have been identified …
Social Isolation, Social And Emotional Loneliness, And Self-Reported Hearing Difficulties In Older Adults With Hearing Loss, Yuliya Borik
Social Isolation, Social And Emotional Loneliness, And Self-Reported Hearing Difficulties In Older Adults With Hearing Loss, Yuliya Borik
Dissertations, Theses, and Capstone Projects
Hearing loss is known to affect communicative ability and has been associated with poor health-related outcomes such as impaired cognition, increased risk for falls, and psychotic manifestations. Social isolation and loneliness are also widely recognized to negatively impact mental and physical health. The purpose of this systematic review is to review literature that explores a relationship between hearing loss with and/or without self-reported hearing difficulties and social isolation and social and emotional loneliness in older adults with hearing loss ranging from mild to profound. The goal is to determine whether there is a direct relationship between subjective and/or objective hearing …
Social Support, Social Companionship, And Social Distress In Young Adults With Cochlear Implants, Arta Ljubanovic
Social Support, Social Companionship, And Social Distress In Young Adults With Cochlear Implants, Arta Ljubanovic
Dissertations, Theses, and Capstone Projects
Research has shown that social support has a positive impact on mental health and decreases levels of stress in young adults with normal-hearing sensitivity. Social relationships are one psychological construct that has not been previously studied in young adults with cochlear implants. In light of the importance of social support in the overall well-being of an individual and the lack of research on this topic in individuals with cochlear implants, the study purpose is to examine social relationships in young adults with cochlear implants and to determine the presence of any significant differences in social relationships between the group with …
Outcomes Of Auditory Brainstem Implantation In Adults With Postlingual Deafness: A Systematic Review, Jillian Friedman
Outcomes Of Auditory Brainstem Implantation In Adults With Postlingual Deafness: A Systematic Review, Jillian Friedman
Dissertations, Theses, and Capstone Projects
Objective:The purpose of this investigation is to conduct a systematic review of the long-term speech-recognition outcomes of ABIs in postlingually deafened adults, and to compare outcomes of ABIs in adults with NF2/tumors to adults without NF2.
Methods: A comprehensive search utilizing various peer reviewed databases via the City University of New York (CUNY) Graduate Center Library was conducted to identify relevant studies investigating speech-recognition outcomes in ABI patients with postlingual deafness, both with and without tumors. Inclusion criteria included studies that involved at least one adult ABI patient (with or without NF2) with postlingual deafness, who was seen for …
Language-Mixing In Discourse In Bilingual Individuals With Non-Fluent Aphasia, Avanthi Paplikar
Language-Mixing In Discourse In Bilingual Individuals With Non-Fluent Aphasia, Avanthi Paplikar
Dissertations, Theses, and Capstone Projects
Language-mixing (LM) as defined by Chengappa (2009, p. 417) is an “intra-sentential phenomenon referred to as the mixing of various linguistic units (morphemes, words, modifiers, phrases, etc.), primarily from two participating grammatical systems”. LM is influenced by grammatical, environmental, and social constraints (e.g., Milroy & Wei, 1995; Bhat & Chengappa, 2005). Researchers have suggested that LM in patients with aphasia is a communicative strategy used to achieve successful exchanges between speakers; the effectiveness of this mixing, however, had yet to be demonstrated quantitatively.
In the current study we investigated whether LM is present in bilingual speakers with aphasia, and if …
Systematic Replication Of The Effects Of A Supplementary, Technology-Assisted, Storybook Intervention For Preschool Children With Weak Vocabulary And Comprehension Skills, Charles R. Greenwood, Judith J. Carta, Elizabeth S. Kelley, Gabriela Guerrero, Na Young Kong, Jane Atwater, Howard Goldstein
Systematic Replication Of The Effects Of A Supplementary, Technology-Assisted, Storybook Intervention For Preschool Children With Weak Vocabulary And Comprehension Skills, Charles R. Greenwood, Judith J. Carta, Elizabeth S. Kelley, Gabriela Guerrero, Na Young Kong, Jane Atwater, Howard Goldstein
Communication Sciences and Disorders Faculty Publications
In 2013, Spencer, Goldstein, Sherman, et al. reported the promising effects of a supplemental, technology-assisted, storybook intervention (Tier 2) containing embedded instruction targeting the oral language learning of preschool children at risk for delays. We sought to advance knowledge of the intervention by replicating it in a new sample and examining children’s responses to the narrator’s instructional prompts and associations with learning outcomes. Results indicated that children were highly successful in responding with the narrator’s task-management prompts (i.e., turn the page), particularly after the first book. Children were much less proficient in correctly responding to the narrator’s word-teaching prompts …
The Effects Of A Social Communication Intervention On The Production Of Emotion Words For Children With Language Impairment, Emilee Anne Longmore
The Effects Of A Social Communication Intervention On The Production Of Emotion Words For Children With Language Impairment, Emilee Anne Longmore
Theses and Dissertations
Many school-age children with a diagnosis of Language Impairment (LI) also have social communication difficulties. Some of these difficulties are related to deficits in emotion understanding. This thesis evaluates the effects of a social communication intervention designed to increase the production of emotion-based words as an indicator of emotional competence. For five elementary school-aged children with LI, the production of emotion-based words was analyzed by first determining the frequency of words produced in preintervention sessions for the following categories: happiness, sadness, anger, fear, surprise, and disgust. Following these measures, the participants received 20 intervention sessions over the course of treatment. …
Bidirectional Interference Between Simulated Driving And Speaking, Kelsey Lynn Simmons
Bidirectional Interference Between Simulated Driving And Speaking, Kelsey Lynn Simmons
Theses and Dissertations
The purpose of this study was to examine interference between concurrently performed speaking and driving tasks. Participants included 60 adults, 30 males and 30 females, with no history of communication disorders. They were divided into three different age groups of 20 participants each: younger (20s), middle-aged (40s), and older (60s). The participants were given a list of topics to consider and were instructed to select eight topics that they could talk about; they completed five practice trials of the driving simulator prior to the experimental recording to eliminate practice effects. Each participant completed the speaking task and driving task both …
Mean Length Of Utterance And Developmental Sentence Scoring In The Analysis Of Children's Language Samples, Laurie Lynne Chamberlain
Mean Length Of Utterance And Developmental Sentence Scoring In The Analysis Of Children's Language Samples, Laurie Lynne Chamberlain
Theses and Dissertations
Developmental Sentence Scoring (DSS) is a standardized language sample analysis procedure that uses complete sentences to evaluate and score a child’s use of standard American-English grammatical rules. Automated DSS software can potentially increase efficiency and decrease the time needed for DSS analysis. This study examines the accuracy of one automated DSS software program, DSSA Version 2.0, compared to manual DSS scoring on previously collected language samples from 30 children between the ages of 2;5 and 7;11 (years;months). The overall accuracy of DSSA 2.0 was 86%. Additionally, the present study sought to determine the relationship between DSS, DSSA Version 2.0, the …
The Association Between Articulator Movement And Formant Trajectories In Diphthongs, Katherine Morris Mckell
The Association Between Articulator Movement And Formant Trajectories In Diphthongs, Katherine Morris Mckell
Theses and Dissertations
The current study examined the association between formant trajectories and tongue and lip movements in the American English diphthongs /aɪ/, /aʊ/, and /ɔɪ/. Seventeen native speakers of American English had electromagnetic sensors placed on their tongues and lips to record movement data along with corresponding acoustic data during productions of the diphthongs in isolation. F1 and F2 trajectories were extracted from the middle 50% of the diphthongs and compared with time-aligned kinematic data from tongue and lip movements. The movement and formant tracks were converted to z-scores and plotted together on a common time scale. Absolute difference scores between kinematic …
Psychometrically Equivalent Bisyllabic Word Lists For Spanish Pediatric Word Recognition Testing, Brenda Karina Peterson
Psychometrically Equivalent Bisyllabic Word Lists For Spanish Pediatric Word Recognition Testing, Brenda Karina Peterson
Theses and Dissertations
While recorded speech audiometry materials have been developed in Spanish for adults, currently there are no speech audiometry materials available in Spanish that are suitable for a pediatric population. Thus, the purposes of this study were (a) to analyze Spanish bisyllabic words previously developed for adults to determine the words' appropriateness when testing word recognition scores in native Spanish-speaking children and (b) to compare the logistic regressions results from the Spanish adult data obtained in a previous study with the logistic regressions from Spanish pediatric data obtained in the present study. Using common-use children's dictionaries in the Spanish language, a …
The Efficacy Of A Literature-Based Social Communication Intervention On Teacher Report Of Sociability For Children With Language Impairment, Mnisa Lyn Harlow
The Efficacy Of A Literature-Based Social Communication Intervention On Teacher Report Of Sociability For Children With Language Impairment, Mnisa Lyn Harlow
Theses and Dissertations
Recent research indicates that children with language impairment (LI) often experience difficulties with social communication. Although the empirical basis for general social communication intervention is growing, information documenting the efficacy of these interventions for children with LI remains limited. The purpose of this study was to examine the effectiveness of a social communication intervention on teacher perceptions of sociability in five elementary-aged children with LI. The intervention focused on the presentation and use of children's stories to target aspects of emotion understanding. The two sociability subscales of the Teacher Behavior Rating Scale (TBRS), impulse control/likeability and prosocial behavior, were used …
Annexin A5 Is The Most Abundant Membrane-Associated Protein In Stereocilia But Is Dispensable For Hair-Bundle Development And Function, Jocelyn F. Krey, Meghan Drummond, Sarah Foster, Edward Porsov, Sarath Vijayakumar, Dongseok Choi, Karen Friderici, Sherri M. Jones, Alfred L. Nuttall, Peter G. Barr-Gillespie
Annexin A5 Is The Most Abundant Membrane-Associated Protein In Stereocilia But Is Dispensable For Hair-Bundle Development And Function, Jocelyn F. Krey, Meghan Drummond, Sarah Foster, Edward Porsov, Sarath Vijayakumar, Dongseok Choi, Karen Friderici, Sherri M. Jones, Alfred L. Nuttall, Peter G. Barr-Gillespie
Department of Special Education and Communication Disorders: Faculty Publications
The phospholipid- and Ca2+-binding protein annexin A5 (ANXA5) is the most abundant membrane-associated protein of ~P23 mouse vestibular hair bundles, the inner ear’s sensory organelle. Using quantitative mass spectrometry, we estimated that ANXA5 accounts for ~15,000 copies per stereocilium, or ~2% of the total protein there. Although seven other annexin genes are expressed in mouse utricles, mass spectrometry showed that none were present at levels near ANXA5 in bundles and none were upregulated in stereocilia of Anxa5−/− mice. Annexins have been proposed to mediate Ca2+-dependent repair of membrane lesions, which could be part of the …
Cultural Competence And Ethical Decision Making For Health Care Professionals, Brenda Louw
Cultural Competence And Ethical Decision Making For Health Care Professionals, Brenda Louw
ETSU Faculty Works
Cultural competence and ethical decision making are two separate, yet intrinsically related concepts which are central to services rendered by all health care professionals. Cultural competence is based on ethical principles and informs ethical decision making. In spite of this important connection, the interrelationship of these two concepts does not receive the attention it deserves in the literature. This issue is addressed by appraising the training and assessment of cultural competence and ethical decision making in the health care professions. The integrated relationship of these two concepts is illustrated within the broader contexts of higher education, research and clinical practice. …
Type And Location Of Speech Disruptions In Adolescents With And Without Specific Language Impairment, Katherine E. Davies
Type And Location Of Speech Disruptions In Adolescents With And Without Specific Language Impairment, Katherine E. Davies
Senior Honors Projects, 2010-2019
This research project analyzed the types and locations of speech disruptions in adolescents with and without Specific Language Impairment (SLI). The narrative samples of 12 adolescents with SLI and 12 typically developing (TD) adolescents were analyzed. Using Schwalbe’s (2012) classification system, the speech disruptions in the 24 narratives were coded for the type and reason for disruption. The broad category of speech disruptions were classified under revisions, repetitions, filled pauses and orphans, and silent pauses. The reason for the disruption was coded as the part of speech of the word that was determined to have caused the disruption. Comparisons were …
Reflection: Effect Of Age On Auditory Brainstem Responses In Mice With Epha4 Mutations, Erica L. Hoogerland
Reflection: Effect Of Age On Auditory Brainstem Responses In Mice With Epha4 Mutations, Erica L. Hoogerland
Senior Honors Projects, 2010-2019
Presbycusis, or age-related hearing loss is a condition that affects approximately 40% of the population over 65 years of age (Gates & Mills, 2005). Studying the effects of EphA4 mutations (wild type, heterozygous, and homozygous) mice is fundamental in understanding the relationship between onset of age-related hearing loss, in both the mammalian population and the human population. In order to further understanding of age-related hearing loss, the researchers evaluated thirty-six mice in a preliminary study from two months to nine months of age. Following data analysis, the researchers confirmed the results by continuing a second round of testing. The hearing …