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Full-Text Articles in Polycyclic Compounds

Neurodevelopmental Effects Associated With In Utero Exposure To Bpa, Maximilian A. Nilsen, Grace A. Carlucci, Cody V. Thompson, Berfin Gul May 2026

Neurodevelopmental Effects Associated With In Utero Exposure To Bpa, Maximilian A. Nilsen, Grace A. Carlucci, Cody V. Thompson, Berfin Gul

Student Work

No abstract provided.


Benzo[A]Pyrene-Induced Multigenerational Gene Expression And Dna Methylation Changes Are Influenced By Paternal Epigenome, Caroline Sturgis May 2024

Benzo[A]Pyrene-Induced Multigenerational Gene Expression And Dna Methylation Changes Are Influenced By Paternal Epigenome, Caroline Sturgis

Honors Theses

The objectives of this study were to determine the sex-dependent contributions to developmental and behavioral effects of preconceptional exposure to benzo[a]pyrene (BaP). BaP is implicated in numerous adverse outcomes in offspring of exposed parents, but the molecular mechanisms for the developmental and multigenerational effects associated with BaP exposures have yet to be fully elucidated. To assess the role of the aryl hydrocarbon receptor (Ahr), a waterborne exposure of the offspring of ahr heterozygous (ahr+/-) parents was conducted. At 120 hpf, BaP treated fish moved significantly less in the dark phase regardless of genotype. At 3 wpf, there …