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Full-Text Articles in Other Chemicals and Drugs

Mental Health Symptom Severity In Cannabis-Using And Non-Using Veterans With Probable Ptsd, Matthew J. Johnson, John D. Pierce, Shahrzad Mavandadi, Johanna Klaus, Diana Defelice, Erin Ingram, David W. Oslin May 2019

Mental Health Symptom Severity In Cannabis-Using And Non-Using Veterans With Probable Ptsd, Matthew J. Johnson, John D. Pierce, Shahrzad Mavandadi, Johanna Klaus, Diana Defelice, Erin Ingram, David W. Oslin

Rowan-Virtua Research Day

BACKGROUND:

Posttraumatic Stress Disorder (PTSD) is a disabling illness suffered by many veterans returning from war. Some veterans believe that cannabis may be therapeutic for PTSD. The purpose of this study was to better understand the association between cannabis use and PTSD symptoms.

METHODS:

The study was a matched case-control cross-sectional evaluation of the psychiatric and sociocultural associations of cannabis use in veterans with probable PTSD. Patient self-report measures were examined comparing cannabis users (cases) to non-users (controls) who were case-matched on age and gender.

RESULTS:

Results indicated that there were no significant differences between cases and controls in mean …


The Teen Vaping Crisis, Jayavignesh Ganesan '21, Cynthia Mu '21, Carolina Seoane '21 May 2019

The Teen Vaping Crisis, Jayavignesh Ganesan '21, Cynthia Mu '21, Carolina Seoane '21

Student Leadership Exchange (SLX)

In today’s society, many teens have the idea that is is cool to vape. This has led to an exponential increase in the number of teenagers addicted to nicotine. This increase is directly caused by nicotine companies, specifically vape companies, presenting their products with appealing and misleading packaging. Indeed, nicotine packages are required to have a warning. However, the warning is usually not taken into consideration, as the warning is not eye-catching. Because of this, we propose that all products containing nicotine, including e-cigarettes, must follow plain packaging regulations. Under plain packaging regulations, companies would be required to have the …


Peptide Functionalized Surfactant Msns, Sonia Barrett Apr 2019

Peptide Functionalized Surfactant Msns, Sonia Barrett

Kansas State University Undergraduate Research Conference

Antibiotic resistance in bacteria has become a rising problem since the first antibiotic was created, further aggravated by the improper overuse to treat common infections, because of this pharmaceutical companies must keep making new and stronger antibiotics. Surfactants are plentiful and effective killers of many surface bacteria and are also varied in their structure, all have a hydrophilic head and long hydrophobic carbon chain. These long hydrophobic carbon chains can pierce through the lipid bilayers that make up bacteria cell membranes and cause cytoplasmic leakage and lysis of the cell wall, leading to cell death. One proposed surfactant is synthesized …


Synthesis Of A Sulfur Variant For Treatment Of Trypanosomiasis, Carlos Vera-Esquivel Mar 2019

Synthesis Of A Sulfur Variant For Treatment Of Trypanosomiasis, Carlos Vera-Esquivel

UNO Student Research and Creative Activity Fair

Previous work in our lab has found diphenyl ether benzylamines showed a successful response with a micromolar concentration of our lead compound to treat the deadly Trypanosamiosis rhodesience. Furthermore, mammalian cell lines saw promising resistance towards damages. The goal of this study was to synthesize a diphenyl thio benzylamine variant. This variant was more active toward T. b. rhodesience but showed more toxicity to both rat 10 (IC50 mM) and human cell lines (HFF, HC-04, U-2 OS, and HEK293). The selectivity index (ratio of toxicity to activity in the same concentration units (SI)) …