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An In Vivo Study Of The Effects Of Perinatal Caffeine Exposure On Synaptic Efficacy In The Hippocampus Of Freely Moving Adult Rats, Jee Eun Park Apr 2016

An In Vivo Study Of The Effects Of Perinatal Caffeine Exposure On Synaptic Efficacy In The Hippocampus Of Freely Moving Adult Rats, Jee Eun Park

Senior Theses and Projects

The synapse from the perforant path to the dentate gyrus has been widely used successfully to demonstrate long-term potentiation, a cellular model underlying learning and memory. Caffeine is one of the most widely consumed psychoactive stimulants in the world. Caffeine consumption increases in alertness, improvements in motor skills, and neurological functions, and these effects have promoted its use throughout history. Although the many short term cognitive benefits of caffeine intake are well understood, the long term effects of caffeine exposure have been widely disputed. Despite this, it is estimated that over 80% of women continue to consume caffeine throughout pregnancy. …


Development Of A Rapid Spme/Gc-Ms Method For The Detection And Quantification Of Synthetic Cathinones In Oral Fluid, David Correll Apr 2013

Development Of A Rapid Spme/Gc-Ms Method For The Detection And Quantification Of Synthetic Cathinones In Oral Fluid, David Correll

Senior Theses and Projects

The recent emergence and widespread abuse of new classes of compounds on the designer drug market as “legal” alternatives to scheduled drugs such as Ecstasy has prompted interest in the development of analytical methods for their detection and characterization. Synthetic cathinones, which are structurally similar to amphetamines, are commonly advertised as a “legal highs” or “herbal highs,” and are marketed under names such as “bath salts” and “plant food.” To avoid drug abuse legislation, a “not for human consumption” warning is typically printed on the label. Their ready availability on the Internet and in “head” shops, convenience stores, and even …