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Full-Text Articles in Other Chemicals and Drugs
Characterization Of Differential Rearing And Sex On 5-Ht2ar Receptor Activation, Kelsey Lowe
Characterization Of Differential Rearing And Sex On 5-Ht2ar Receptor Activation, Kelsey Lowe
Theses/Capstones/Creative Projects
The prevalence of substance use disorders (SUDs) continues to rise while the number of medications to combat this deadly disorder remains stagnant. Entirely new thinking about what exemplifies a possible therapeutic is needed. Hallucinogens are continually being studied more as possible treatments for many psychological conditions, including SUDs. Classic hallucinogens engage many serotonin and monoamine systems, but the hallucinogenic effects are driven by serotonin 5-HT2A receptor (5-HT2AR) activation. Forced social isolation induces chronic stress, increases 5-HT2AR expression in the cortex and have been suggested to play a role in the comorbidity between stress, maladaptive coping, …
Accelerometry-Based Analysis Of Postural Sway In Parkinson's Disease Patients With Levodopa-Induced Dyskinesia, Chandler Brock
Accelerometry-Based Analysis Of Postural Sway In Parkinson's Disease Patients With Levodopa-Induced Dyskinesia, Chandler Brock
UNO Student Research and Creative Activity Fair
Parkinson’s disease (PD) is a progressive neurodegenerative disorder, with patient numbers projected to double to 12 million in the next 20 years. Levodopa-induced dyskinesia (LID) is a major problem associated with the long-term use of levodopa for symptomatic treatment of PD. These involuntary movements can become disabling and may interfere with quality of life. Our prior research showed that PD w/ LID were less stable while standing (i.e., increased postural sway) and had a higher incidence of falls. The aim of this study is to determine if postural sway properties are altered by LID via decomposing the sway signal. We …