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Characterization Of Differential Rearing And Sex On 5-Ht2ar Receptor Activation, Kelsey Lowe May 2023

Characterization Of Differential Rearing And Sex On 5-Ht2ar Receptor Activation, Kelsey Lowe

Theses/Capstones/Creative Projects

The prevalence of substance use disorders (SUDs) continues to rise while the number of medications to combat this deadly disorder remains stagnant. Entirely new thinking about what exemplifies a possible therapeutic is needed. Hallucinogens are continually being studied more as possible treatments for many psychological conditions, including SUDs. Classic hallucinogens engage many serotonin and monoamine systems, but the hallucinogenic effects are driven by serotonin 5-HT2A receptor (5-HT2AR) activation. Forced social isolation induces chronic stress, increases 5-HT2AR expression in the cortex and have been suggested to play a role in the comorbidity between stress, maladaptive coping, …


Relationships Between Delinquency And Substance Use Among Adolescents Emancipating From Foster Care, Svetlana Shpiegel, Jamey J. Lister, Richard Isralowitz May 2016

Relationships Between Delinquency And Substance Use Among Adolescents Emancipating From Foster Care, Svetlana Shpiegel, Jamey J. Lister, Richard Isralowitz

Department of Social Work and Child Advocacy Faculty Scholarship and Creative Works

Adolescents emancipating from foster care exhibit high rates of both delinquency and substance use, although it is less clear how these behaviors relate to one another. We aimed to examine the reciprocal relationships between these risk behaviors while accounting for relevant child welfare factors. We use data from the Multi-Site Evaluation of Foster Youth Programs to explore longitudinal associations between delinquent behaviors and substance use (tobacco, alcohol, and marijuana) among youths ages 17 and 18 (N = 429). Delinquency at age 17 was a positive predictor of substance use at age 18, after controlling for baseline use of substances. …