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Bio-Identical Hormone Therapy: Understanding Women's Decision-Making Process And Family Physicians' Views, Lemmese Alwatban Oct 2013

Bio-Identical Hormone Therapy: Understanding Women's Decision-Making Process And Family Physicians' Views, Lemmese Alwatban

Electronic Thesis and Dissertation Repository

This thesis explored women’s and family physicians’ experiences with Bio-identical Hormone Therapy (BHT). It aimed to develop a deeper understanding of women’s decision-making process in choosing this therapeutic modality, and the influence family physicians may have on this process. To capture the phenomenon under study, two complementary and sequential qualitative studies were conducted. The studies involved in-depth interviews with women using BHT and family physicians that care for this population. The collective findings of both studies demonstrated the complexity of menopause care. The findings illuminated the major factors involved in women’s BHT decision-making process. It also offered important information about …


Effects Of Prenatal Testosterone On The Reproductive And Metabolic Neurons Of The Sheep Hypothalamus, Maria Cernea Aug 2013

Effects Of Prenatal Testosterone On The Reproductive And Metabolic Neurons Of The Sheep Hypothalamus, Maria Cernea

Electronic Thesis and Dissertation Repository

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting reproductively aged women. Women with PCOS and ewes prenatally exposed to testosterone (T) show similar reproductive and metabolic defects, including anovulatory dysfunctions stemming from abnormal gonadotropin releasing hormone (GnRH) secretion and insulin resistance. For this dissertation, I examined the effects of prenatal T treatment on androgen receptor (AR) and insulin receptor (IR) expression with the reproductive and metabolic neurons of the hypothalamus, the ARC KNDy (co-expressing kisspeptin, neurokinin B/dynorphin), AgRP (agouti-related peptide) and proopiomelanocortin (POMC) neurons, and the preoptic area (POA) kisspeptin neurons, and the GnRH neurons. …