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Full-Text Articles in Chemicals and Drugs
Atorvastatin Alters Neuronal Morphology Data Set, Carolyn L. Pytte
Atorvastatin Alters Neuronal Morphology Data Set, Carolyn L. Pytte
Publications and Research
Statins are highly effective and widely prescribed cholesterol lowering drugs. However, statins cross the blood-brain barrier and decrease neural cholesterol in animal models, raising concern that long-term statin use may impact cholesterol-dependent structures and functions in the brain. Cholesterol is a fundamental component of cell membranes and experimentally decreasing membrane cholesterol has been shown to alter cell morphology in vitro. In addition, brain regions that undergo adult neurogenesis rely on local brain cholesterol for the manufacture of new neuronal membranes. Thus neurogenesis may be particularly vulnerable to long-term statin use. Here we asked whether oral statin treatment impacts neurogenesis …
Table B: Impacts Of Utensil Use In Preparation, Robert Yokel
Table B: Impacts Of Utensil Use In Preparation, Robert Yokel
Aluminum in Beverages and Foods: A Compilation
No abstract provided.