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Mouth Exposure To Carbohydrate Prior To Exercise Possibly Impairs The Efficacy Of Carbohydrate Mouth Rinsing During Exercise, Kevin Decker May 2017

Mouth Exposure To Carbohydrate Prior To Exercise Possibly Impairs The Efficacy Of Carbohydrate Mouth Rinsing During Exercise, Kevin Decker

Masters Theses, 2010-2019

Decker K. P., M. J. Saunders, N. D. Luden, C. J. Womack, and N. J. Hladick. Mouth Exposure to Carbohydrate Prior to Exercise Possibly Impairs the Efficacy of Carbohydrate Mouth Rinsing during Exercise. Purpose: Carbohydrate mouth-rinsing (CHO-MR) during intense endurance exercise has been associated with improved cycling performance, due to neurological influences. However, prior studies have reported the efficacy of CHO-MR is attenuated following a pre-exercise meal. To determine if this outcome is related to desensitization of CHO receptors (rather than metabolic effects following digestion), this study will investigate whether CHO-MR prior to exercise influences cycling performance when CHO-MR …


Clinical Study Of Canine Tear Lacritin As A Treatment For Dry Eye, Katherine E. Kelly May 2016

Clinical Study Of Canine Tear Lacritin As A Treatment For Dry Eye, Katherine E. Kelly

Senior Honors Projects, 2010-2019

Keratoconjunctivitis sicca (KCS), the deficiency of tears also known as dry eye, is a prevalent disease that affects both humans and canines. The current treatment for dye eye, cyclosporine (Restatis®), only provides temporary relief, is often associated with discomfort and is inconsistently effective. Lacritin is a naturally occurring tear glycoprotein secreted from the human and canine lacrimal glands. It has been shown that lacritin stimulates basal tearing in rabbits when applied topically. This study characterized the amount and form of lacritin found in the tears of dogs with healthy and dry eyes—information which may be applied to the development of …


Colloidal And Biological Properties Of Triscationic Amphiphiles With One Or Two Tails, John N. Marafino Dec 2014

Colloidal And Biological Properties Of Triscationic Amphiphiles With One Or Two Tails, John N. Marafino

Masters Theses, 2010-2019

The decline in the development of novel antimicrobials, combined with the misusage and over prescription of antibiotics, has contributed to the increasing prevalence of antimicrobial-resistant infections. Thus development of effective novel disinfectants could reduce the transmission of pathogens and decrease the risk of infection by antibiotic resistant organisms. The antimicrobial activity of amphiphiles, compounds with hydrophobic and hydrophilic regions, was first reported in 1935, and has influenced the synthesis of amphiphiles with variations in structure. In this study, three series of amphiphiles were synthesized by two subsequent Menshutkin reactions. Each amphiphile contains one or two hydrocarbon tails ranging from 8 …