Bioethics and Medical Ethics Commons^™

Genotypes And Phenotypes In Children With Short Stature: Clinical Indicators Of Shox Haploinsufficiency, Gudrun Rappold, Werner F. Blum, Elena P. Shavrikova, Brenda J. Crowe, Ralph Roeth, Charmian A. Quigley, Judith L. Ross, Beate Niesler

Department of Pediatrics Faculty Papers

Background: Short stature affects approximately 2% of children, representing one of the more frequent disorders for which clinical attention is sought during childhood. Despite assumed genetic heterogeneity, mutations or deletions of the short stature homeobox-containing gene (SHOX) are found quite frequently in subjects with short stature. Haploinsufficiency of the SHOX gene causes short stature with highly variable clinical severity, ranging from isolated short stature without dysmorphic features to Léri-Weill syndrome, and with no functional copy of the SHOX gene, Langer syndrome.

Methods: To characterise the clinical and molecular spectrum of SHOX deficiency in childhood we assessed …

Stealing What's Free: Exploring Compensation To Body Parts Sources For Their Contribution To Profitable Biomedical Research, Jo-Anne Yau

The University of New Hampshire Law Review

[Excerpt] “At first blush, donating body parts in the name of science appears to be a beautiful solution to the problem of scarce body parts for research advancements. But a closer investigation reveals an ugly fact: the philanthropic donors—referred to as “Sources” in this article—are subjected to physical and financial exploitation.

Sources play a crucial and indispensable role in biotechnology. Without human body parts, most medical discoveries would not have been possible. Handsome profits can be derived from successful discoveries. But currently in the United States, when a Source provides body parts for research purposes, the researcher, research foundation, and …

Higher Self-Reported Physical Activity Is Associated With Lower Systolic Blood Pressure: The Dietary Intervention Study In Childhood (Disc) , Samuel S. Gidding, Bruce A. Barton, Joanne A. Dorgan, Sue Y.S. Kimm, Peter O. Kwiterovich, Normal L. Lasser, Alan M. Robson, Victor J. Stevens, Linda Van Horn, Denise G. Simons-Morton

Department of Pediatrics Faculty Papers

Objective: Children participating in a dietary clinical trial were studied to assess physical activity patterns in boys and girls longitudinally from late childhood through puberty; and to determine the association of level of physical activity on systolic blood pressure (SBP), low density lipoprotein (LDL) cholesterol, and body mass index (BMI).

Patients and Methods: In the Dietary Intervention Study in Childhood (DISC), a randomized clinical trial of a reduced saturated fat and cholesterol diet in 8-10 year olds with elevated LDL, a questionnaire that determined time spent in five intensity levels of physical activity was completed at baseline and …

Mid-Atlantic Ethics Committee Newsletter, Fall 2006-Winter 2007

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Update - October 2006, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Physician-Assisted Suicide: A Jewish Perspective
-- Jack W. Provonsha posthumously honored with Centennial Vanguard Award
-- Student updates
-- Associate Scholars of the Center for Christian Bioethics
-- Editorial

Who Decides Whether A Patient Lives Or Dies?, Diane E. Hoffmann, Jack Schwartz

Faculty Scholarship

No abstract provided.

Center For Professional Ethics, Fall 2006, Case Western Reserve University

Center for Professional Ethics

Table of Contents:

• Director's Corner: A New Beginning by Robert P. Lawry
• The Global is Finally Local: Some Notes on Ethics, A Conversation with Bill Deal, Inamori Professor
• Are You Ready to Take Free Exercise Rights Seriously? Alan Brownstein Explains Why You Should
• Religious Lawyering: Professor Russell Pearce Keeps His Faith
• Author David Callahan Asks: What Does Our "Cheating Culture' Say About Us?
• Academic Integrity: Students Speak

Report Of The Working Group On Animal Distress In The Laboratory, Marilyn Brown, Larry Carbone, Kathleen Conlee, Marian Dawkins, Ian J. Duncan, David Fraser, Gilly Griffin, Victoria A. Hampshire, Lesley A. Lambert, Joy A. Mench, David Morton, Jon Richmond, Bernard E. Rollin, Andrew N. Rowan, Martin L. Stephens, Hanno Würbel

Laboratory Experiments Collection

Finding ways to minimize pain and distress in research animals is a continuing goal in the laboratory animal research field. Pain and distress, however, are not synonymous, and often measures that alleviate one do not affect the other. Here, the authors provide a summary of a meeting held in February 2004 that focused on distress in laboratory animals. They discuss the difficulties associated with defining ‘distress,’ propose methods to aid in recognizing and alleviating distressful conditions, and provide recommendations for animal research conduct and oversight that would minimize distress experienced by laboratory animals.

Revisiting The Ethics Of Hiv Prevention Research In Developing Countries, Charles Weijer, Guy Leblanc

Philosophy Presentations

Issues: We present key aspects of our paper, commissioned by UNAIDS in 2005, entitled, “Revisiting the ethics of HIV prevention research in developing countries.” In 2004 and 2005 we witnessed the closure or suspension of three international clinical trials testing tenofovir in the prevention of HIV infection in high risk groups due to the failure to provide free treatment to those who seroconvert during the conduct of the study. We examine critically moral claims for the provision of treatment to those who seroconvert in HIV prevention trials and ask whether it is a matter of moral obligation or moral negotiation? …

Mid-Atlantic Ethics Committee Newsletter, Summer 2006

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

The Ethics Of Referral, Bernard Rollin

Professional Veterinary Ethics Collection

The rapid growth of veterinary specialty practices has created a number of vexatious ethical issues relevant to veterinary medicine. The preeminent question pertains to “the duty to refer.” Do primary care practitioners have such a moral duty? If so, when does this duty arise? Does it pertain in all cases where specialized knowledge is relevant to a disease?

This raises the fundamental question of “Veterinary Ethics” — namely, does the veterinarian ideally have primary obligation to the client/owner or the animal? (1) There are 2 possible ideal types that a veterinarian can aim for — the Garage Mechanic Model or …

Response - Jay Katz: From Harms To Risks, Larry I. Palmer

Faculty Publications

No abstract provided.

Update - June 2006, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Provonsha on Religion and Bioethics
-- Editorial
-- The Urgency Dilemma: Is Life Extension Research a Temptation or a Test?
-- 2006 Biomedical and Clinical Ethics Master's Degree Graduates
-- Changes for the Center's Bioethics Grand Rounds
-- 2006-2007 Health and Faith Forum

The Commodification Of International Education, Howard Dooley

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Universities And Corporations: A Selection Of Papers Presented At Tire Western Michigan University Emeriti Council Forum, Center Of The Study Of Ethics In Society

Center for the Study of Ethics in Society Papers

A selection of papers presented at the WMU Emeriti Council Forum.

The College Of Engineering And Applied Sciences & The Btr-A Partnership With Purpose, Michael B. Atkins, Kurt Hayden

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Applying A Business Model To The University, John Neill

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Recent Developments In International Education At Wmu, Ronald Davis

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Media Ethics: The Powerful And The Powerless, Elaine E. Englehardt

Center for the Study of Ethics in Society Papers

Papers presented for the Center of the Study of Ethics in Society Western Michigan University.

Epilogue: Universities And Corporations, Robert Kauffman

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Introduction: The Entrepreneurial University, Joseph Ellin

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Cultural Contradictions And Ethical Dilemmas In The Corporate-Styled University, Eric Gould

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University

The Entrepreneurial University: Rewards & Risks, Samuel M. Hines Jr.

Center for the Study of Ethics in Society Papers

Published by the Center of the Study of Ethics in Society Western Michigan University.

Update - March 2006, Loma Linda University Center For Christian Bioethics

Update

In this issue:

[ The year in review: A look back at 2005 at the Center for Christian Ethics ]
-- 2005 National Bioethics Conference
-- Spirituality and Health Conference
-- Bioethics Summer Camp
-- Bioethics Grand Rounds 2004 through 2005 Loma Linda University
-- Bioethics Grand Rounds 2005 Off-campus
-- Biomedical and Clinical Ethics, Alumni update

-- Editorial
-- The Thompson Ethics Library
-- 2005 Contributor's Convocation
-- Bioethics Grand Rounds goes national
-- Center for Christian Bioethics, Endowment funding
-- 2006 Jack W. Provonsha Lecture Series
-- Center for Christian Bioethics funding sources July 2005 through February 2006

Causes And Mechanisms, An Interview With Dr. Jeremiah Stamler, Samuel S. Gidding

Department of Pediatrics Faculty Papers

Dr. Jeremiah Stamler began his career in New York City and moved to Chicago in 1947 with his wife Rose, to accept a basic research position with Dr. Louis N. Katz. Early animal studies convinced him of the role of dietary factors, particularly cholesterol and salt, in the etiology of atherosclerotic vascular disease. Because of a strong interest in public health, he began the first of many population based cohort studies in the 1950s that subsequently defined the role of health behaviors (adverse nutrition choices, tobacco use, low physical activity) and associated measurable biologic traits, now called risk factors, in …

Increasing Illness Severity In Very Low Birth Weight Infants Over A 9-Year Period, David A. Paul, Kathleen H. Leef, Robert G. Locke, Louis Bartoshesky, Judy Walrath, John L. Stefano

Department of Pediatrics Faculty Papers

Background: Recent reports have documented a leveling-off of survival rates in preterm infants through the 1990's. The objective of this study was to determine temporal changes in illness severity in very low birth weight (VLBW) infants in relationship to the outcomes of death and/or severe IVH.

Methods: Cohort study of 1414 VLBW infants cared for in a single level III neonatal intensive care unit in Delaware from 1993-2002. Infants were divided into consecutive 3-year cohorts. Illness severity was measured by two objective methods: the Score for Neonatal Acute Physiology (SNAP), based on data from the 1st day of …

Historical Perspectives On Attitudes Concerning Death And Dying, David San Filippo Ph.D.

Faculty Publications

Beliefs and practices concerning death have changed throughout human history. In pre-modern times, death at a young age was common due to living conditions and medical practices. As medical science has advanced and helped humans live longer, attitudes and responses to death also have changed. In modern Western societies, death is often ignored or feared. Changes in lifestyles and improved medical science have depersonalized death and made it an encroachment on life instead of part of life. This has left many people ill equipped to deal with death when it touches their lives.

Religious Interpretations Of Death, Afterlife & Ndes, David San Filippo Ph.D.

Faculty Publications

This E-book reviews religious beliefs concerning death, afterlife, and near-death experiences. The discussion will provide commentary regarding the similarities between different religious beliefs and experiences concerning death, as well as between religious interpretations of near-death experiences.

Perspectives On The Fears Of Death & Dying, David San Filippo Ph.D.

Faculty Publications

This E-Book will examine some perspectives on fear, the fears of death, and constructs used to overcome or deal with the fears of death. By examining the literature on fear in general, a framework can be developed to understand how individuals become fearful. In the section, “Fears of Death,” what people fear about death and why they fear it will be discussed.

Philosophical, Psychological & Spiritual Perspectives On Death & Dying, David San Filippo Ph.D.

Faculty Publications

This Ebook reviews the philosophical perspectives on death, the psychological perspectives on death and the fears of death and some religious perspectives of death. The philosophic section will review perspectives of death from ancient Greece through modernity. The psychological section will review death, and the fear of death, from the perspectives of psychoanalytic, humanistic, and existentialist theories. The religious section will provide a brief overview of Prehistoric, African, Buddhist, Hindu, Islamic, Jewish, and Christian religious beliefs concerning death and afterlife.