Sense Organs Commons^™

Photoreception And Eye Regeneration Mechanisms In Planarians, Taylor R. Birkholz

Dissertations

Although humans lack the ability to regenerate complete organs and limbs following amputation or injury, there are many other species (both vertebrates and invertebrates) that can. Significant advances have been made in understanding the genetic mechanisms that regulate organ regeneration in these species, including regeneration of eye tissues such as the lens and retina. Planarians are an established historical model used to study regeneration due to their ability to regenerate any organ, including the eye. With recent advances in molecular genetic analyses, planarians are now an emerging model for the specific study of eye regeneration mechanisms. Furthermore, regeneration of the …

The Sophistical Tongue Map, Rebecca Filler

Emerging Writers

Finalist in the Academic Category of the 2018 Emerging Writers Contest. This essay examines the evolution of the "tongue map."

Early Uneven Ear Input Induces Long-Lasting Differences In Left-Right Motor Function, Michelle W. Antoine, Xiaoxia Zhu, Marianne Dieterich, Thomas Brandt, Sarath Vijayakumar, Nicholas Mckeehan, Joseph C. Arezzo, R. Suzanne Zukin, David A. Borkholder, Sherri M. Jones, Robert D. Frisina, Jean M. Hébert

Department of Special Education and Communication Disorders: Faculty Publications

How asymmetries in motor behavior become established normally or atypically in mammals remains unclear. An established model for motor asymmetry that is conserved across mammals can be obtained by experimentally inducing asymmetric striatal dopamine activity. However, the factors that can cause motor asymmetries in the absence of experimental manipulations to the brain remain unknown. Here, we show that mice with inner ear dysfunction display a robust left or right rotational preference, and this motor preference reflects an atypical asymmetry in cortico-striatal neurotransmission. By unilaterally targeting striatal activity with an antagonist of extracellular signal-regulated kinase (ERK), a downstream integrator of striatal …

Water Transport In The Lateral Line Canal Of The Intertidal Fish Xiphister Mucosus (Girard 1858) And Its Significance To Evaporative Water With Preliminary Observations Of The Metabolic Consequences Of Water Loss, Whitney Anne Gayer

Dissertations and Theses

The lateral line canal system is a sensory organ found in all teleost fish that has a wide range of morphological variation. Variation in morphology may often be the result of evolutionary necessity where the need for function dictates form. Xiphister mucosus is an amphibious Stichaeid fish that inhabits the rocky intertidal zone of the northeastern Pacific Ocean. The rocky intertidal is considered an extreme environment where crashing waves and ebbing tides may require the specialization of adaptations for surviving the many abiotic stressors encountered there.

The lateral line trunk canal of Xiphister is regarded as unique among teleosts with …

Il-1r And Myd88 Contribute To The Absence Of A Bacterial Microbiome On The Healthy Murine Cornea, Stephanie J. Wan, Aaron B. Sullivan, Peyton Shieh, Matteo M. E. Metruccio, David J. Evans, Carolyn R. Bertozzi, Suzanne M. J. Fleiszig

Faculty Publications & Research of the TUC College of Pharmacy

Microbial communities are important for the health of mucosal tissues. Traditional culture and gene sequencing have demonstrated bacterial populations on the conjunctiva. However, it remains unclear if the cornea, a transparent tissue critical for vision, also hosts a microbiome. Corneas of wild-type, IL-1R (-/-) and MyD88 (-/-) C57BL/6 mice were imaged after labeling with alkyne-functionalized D-alanine (alkDala), a probe that only incorporates into the peptidoglycan of metabolically active bacteria. Fluorescence in situ hybridization (FISH) was also used to detect viable bacteria. AlkDala labeling was rarely observed on healthy corneas. In contrast, adjacent conjunctivae harbored filamentous alkDala-positive forms, that also labeled …

Changes In Balance And Joint Position Sense During A 12-Day High Altitude Trek: The British Services Dhaulagiri Medical Research Expedition, Sarah B. Clarke, Kevin Deighton, Caroline Newman, Gareth Nicholson, Liam Gallagher, Christopher J. Boos, Adrian Mellor, David R. Woods, John P. O'Hara

Journal Articles

Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested whether exposure to a 12-day trek with a gradual ascent to high altitude impairs postural control and joint position sense. This was a repeated measures observational study of 12 military service personnel (28±4 years). Postural control (sway velocity measured by a portable force platform) during standing balance, a Sharpened Romberg Test and knee joint position sense were measured, in England (113m elevation) and at 3 research camps (3619m, 4600m and 5140m) on a 12-day high altitude trek in the …