Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Cell and Developmental Biology (2)
- Life Sciences (2)
- Medical Sciences (2)
- Behavioral Medicine (1)
- Biochemistry, Biophysics, and Structural Biology (1)
-
- Cancer Biology (1)
- Cardiovascular Diseases (1)
- Cardiovascular System (1)
- Chemicals and Drugs (1)
- Clinical Epidemiology (1)
- Cognitive Science (1)
- Developmental Biology (1)
- Disease Modeling (1)
- Diseases (1)
- Embryonic Structures (1)
- Endocrinology (1)
- Hormones, Hormone Substitutes, and Hormone Antagonists (1)
- Maternal and Child Health (1)
- Medical Physiology (1)
- Medical Specialties (1)
- Molecular Biology (1)
- Neurology (1)
- Obstetrics and Gynecology (1)
- Pathological Conditions, Signs and Symptoms (1)
- Physiology (1)
- Public Health (1)
- Reproductive and Urinary Physiology (1)
- Institution
- Keyword
Articles 1 - 3 of 3
Full-Text Articles in Endocrine System
Investigating The Modulation Of Metastasis By Dax-1 In Adrenal Carcinoma Cells, Aarya Mishra
Investigating The Modulation Of Metastasis By Dax-1 In Adrenal Carcinoma Cells, Aarya Mishra
Undergraduate Honors Theses
The nuclear hormone receptor (NHR), DAX-1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1), is important in adrenal and gonadal development as well as steroidogenesis. It is encoded by the NR0B1 gene and functions mainly as a transcriptional repressor. Classified as an orphan receptor within the NHR superfamily, DAX-1 has been shown to inhibit other NHRs including estrogen receptor, androgen receptor and steroidogenic factor 1. DAX-1 is found to be underexpressed in breast and prostate cancers and, specifically in prostate cancer, is believed to be a transcriptional repressor of genes that are involved in epithelial-mesenchymal transition …
Parental Instincts: The Neurological And Biological Factors Associated With Parenthood, Jared Reeder
Parental Instincts: The Neurological And Biological Factors Associated With Parenthood, Jared Reeder
Undergraduate Honors Theses
The following project involves a systematic review of the scientific literature on neural and biological changes of mothers and fathers in parenthood. Until very recently, little scientific research was devoted to studying how bearing children affects a man or woman’s long-term biology. Over the last twenty years, studies of neuroplastic changes in new mothers show specific neural mechanisms responsible for altering the behaviors of mothers during and after pregnancy. These changes in neuroplasticity alter behavior in such a way that led to mothers requiring less sleep and being more prone to hearing the cries of their children. In addition to …
The Impact Of Prolonged Estrogen Deficiency On Cardiac Hypertrophy Following Chronic Sympathetic Stimulation, Isabelle Krueger
The Impact Of Prolonged Estrogen Deficiency On Cardiac Hypertrophy Following Chronic Sympathetic Stimulation, Isabelle Krueger
Undergraduate Honors Theses
Cardiovascular disease (CVD) is the leading cause of death for both men and women in developed countries. Compared to age-matched males, premenopausal women experience lower rates of CVD but this increases after menopause. A central feature in CVD is changes in sympathetic regulation leading to pathological changes such as cardiac hypertrophy characterized by changes in cardiomyocyte size due to overcompensation of the muscle following injury. The goal of this research is to study the effect of prolonged estrogen loss on cardiac hypertrophy following chronic sympathetic stimulation. Female mice were ovariectomized at 10 weeks of age and treated with Isoproterenol to …