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Stem cells

2019

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Full-Text Articles in Cells

Bmp Regulation Of Cyst Stem Cell Division In The Drosophila Testis Stem Cell Niche, Mohamoud Ahmed Apr 2019

Bmp Regulation Of Cyst Stem Cell Division In The Drosophila Testis Stem Cell Niche, Mohamoud Ahmed

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Adult stem cells are found throughout the body and divide to replace dead cells or regenerate damaged tissues. We study the Drosophila melanogaster (fruit fly) testis as a model to investigate how adult stem cells are maintained by the intricate microenvironments in which they live, called stem cell niches. Many basic characteristics of adult stem cells in higher organisms were first discovered in the simple stem cell niches found in Drosophila. The testis niche is comprised of two distinct stem cells called germline stem cells (GSCs) and cyst stem cells (CySCs). This niche also contains a structure called the hub …