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Cardiovascular System Commons

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Articles 1 - 9 of 9

Full-Text Articles in Cardiovascular System

Dairy Consumption And Hypertension: Arterial Stiffness And Pulse Pressure, Merrill F. Elias, Gregory A. Dore, Georgina E. Crichton Feb 2013

Dairy Consumption And Hypertension: Arterial Stiffness And Pulse Pressure, Merrill F. Elias, Gregory A. Dore, Georgina E. Crichton

Maine-Syracuse Longitudinal Papers

No abstract provided.


Hypertension And Cognitive Functioning: A Perspective In Historical Context, Merrill F. Elias, Amanda L. Goodell, Gregory A. Dore Jul 2012

Hypertension And Cognitive Functioning: A Perspective In Historical Context, Merrill F. Elias, Amanda L. Goodell, Gregory A. Dore

Maine-Syracuse Longitudinal Papers

Our objective is to characterize the development of the literature on hypertension and cognitive functioning from a historical perspective. This goal was stimulated by the review on “Historical Trends and Milestones in Hypertension Research” in the October 2012 issue of Hypertension. Our specific aims are threefold: (1) to trace and describe the history of this area of research; (2) to identify milestones in knowledge and methods; and (3) to discuss briefly how this literature translates into patient care. The topic is of major relevance to research and practice because hypertension is a well-known risk factor for decline in cognitive performance …


From Blood Pressure To Physical Disability: The Role Of Cognition, Merrill F. Elias, Gregory A. Dore, Adam Davey, Michael A. Robbins, Penelope K. Elias Apr 2010

From Blood Pressure To Physical Disability: The Role Of Cognition, Merrill F. Elias, Gregory A. Dore, Adam Davey, Michael A. Robbins, Penelope K. Elias

Maine-Syracuse Longitudinal Papers

We examined the hypothesis that lowered cognitive performance plays a role in the relation between elevated blood pressure and physical disability in performing basic physical tasks. A community-based sample (N = 1025) free from stroke and dementia (mean age: 61.1 years; SD: 13.0 years; 59.8% women) was used. Using path analysis, systolic and diastolic blood pressures (predictor variable) measured over multiple longitudinal examinations were averaged and related to multiple measures of cognition (intermediate variable) and physical ability (PA; outcome variable) measured at wave 6 of the Maine-Syracuse Study. PA was indexed by time required to execute standing, walking, and turning …


Arterial Pulse Wave Velocity And Cognition With Advancing Age, Merrill F. Elias, Michael A. Robbins, Marc M. Budge, Walter P. Abhayaratna, Gregory A. Dore, Penelope K. Elias Feb 2009

Arterial Pulse Wave Velocity And Cognition With Advancing Age, Merrill F. Elias, Michael A. Robbins, Marc M. Budge, Walter P. Abhayaratna, Gregory A. Dore, Penelope K. Elias

Maine-Syracuse Longitudinal Papers

We hypothesized that carotid-femoral pulse wave velocity (PWV), a marker of arterial stiffness, interacts with age such that the magnitude of associations between PWV and cognitive performance are greater with increasing age and that this interaction is observed despite adjustments for demographic variables, mean arterial pressure, and cardiovascular risk factors. PWV was estimated using applanation tonometry in 409 dementia- and stroke-free participants of the Maine-Syracuse Longitudinal Study (24 to 92 years of age; 62.3% women). Using linear regression analyses in a cross-sectional design, associations between PWV and age and the interaction of PWV and age were examined in relation to …


Blood Pressure And Disability: First Steps In Future Studies, Michael A. Robbins, Penelope K. Elias, Merrill F. Elias Jan 2008

Blood Pressure And Disability: First Steps In Future Studies, Michael A. Robbins, Penelope K. Elias, Merrill F. Elias

Maine-Syracuse Longitudinal Papers

No abstract provided.


Blood Pressure And Cognitive Function In An African-American And A Caucasian-American Sample: The Maine-Syracuse Study, Michael A. Robbins, Merrill F. Elias, Penelope K. Elias, Marc M. Budge Apr 2005

Blood Pressure And Cognitive Function In An African-American And A Caucasian-American Sample: The Maine-Syracuse Study, Michael A. Robbins, Merrill F. Elias, Penelope K. Elias, Marc M. Budge

Maine-Syracuse Longitudinal Papers

Objective: The primary purpose of this study was to examine associations between indices of blood pressure (BP) and cognitive function for African-American participants in the Maine-Syracuse Longitudinal Study (MSLS). Corresponding data for the Caucasian-American MSLS participants were included to provide a basis for comparison. Interactions of age with BP indices were also assessed in relation to cognitive function. Methods: Data were drawn from the baseline MSLS questionnaires, medical interviews and examinations, Wechsler Adult Intelligence Scale subtests, and measurements of BP for 1563 participants, of whom 147 were African American. Multiple linear regression analyses were employed to examine the relationship between …


Low Blood Pressure And Depression: Comorbidity And Competing Outcomes, Michael A. Robbins, Penelope K. Elias, Merrill F. Elias Jan 2000

Low Blood Pressure And Depression: Comorbidity And Competing Outcomes, Michael A. Robbins, Penelope K. Elias, Merrill F. Elias

Maine-Syracuse Longitudinal Papers

No abstract provided.


Effects Of Antihypertensive Medications On Quality Of Life In Elderly Hypertensive Women, Sydney H. Croog, Merrill F. Elias, Theodore Colton, Robert M. Baume, Sandra R. Leiblum, C David Jones, H Mitchell Perry, W Dallas Hall Jan 1994

Effects Of Antihypertensive Medications On Quality Of Life In Elderly Hypertensive Women, Sydney H. Croog, Merrill F. Elias, Theodore Colton, Robert M. Baume, Sandra R. Leiblum, C David Jones, H Mitchell Perry, W Dallas Hall

Maine-Syracuse Longitudinal Papers

The impact of antihypertensive medications on the quality of life of elderly hypertensive women has rarely been systematically evaluated in large clinical trials using drugs from the new generations of pharmaceutic preparations. We carried out a multicenter, randomized double-blind clinical trial with 309 hypertensive women aged 60 to 80 years to assess effects of atenolol, enalapril, and isradipine on measures of quality of life over a 22-week period. The patients had mild to moderate hypertension. Hydrochlorothiazide was added to treatment if monotherapy was inadequate in lowering blood pressure. At the conclusion of the trial the three drug groups did not …


Relationship Of Age And Hypertension To Neuropsychological Test Performance, Clyde A. Pentz Iii, Merrill F. Elias, W Gibson Wood, Norman A. Schultz, John Dineen Jan 1979

Relationship Of Age And Hypertension To Neuropsychological Test Performance, Clyde A. Pentz Iii, Merrill F. Elias, W Gibson Wood, Norman A. Schultz, John Dineen

Maine-Syracuse Longitudinal Papers

Young adult (X- = 29) and middle aged (X- =50) hypertensive and normotensive subjects were compared with respect to seven neuropsychological test scores derived from tests on the Halstead-Reitan battery. Age main effects, with inferior performance for the middle aged subjects, were observed for the localization and time portions of the Tactile Performance Test (TPT) and for the Trail Making A test. The multivariate age effect was significant for the composite of seven scores. A multivariate blood pressure main effect was obtained and main effect blood pressure was significant for the category test; hypertensives made more errors than normotensives. A …