Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Tracking Plasma Lactate Concentration In Vivo With A Catheter-Tip L-Lactate Sensor, Brett T. Weinzapfel, Mark D. Ball, Lee R. Waite, Nacer E. Abrouk, Shun P. Lim

Mathematical Sciences Technical Reports (MSTR)

To circumvent the problems of repeated blood sampling for in vitro analysis, a catheter-tip L-lactate sensor has been developed. The sensor was tested in anesthetized pigs (n=6). The sensor in vivo tracked the lactate concentration non-linearly, seeming to obey Michaelis-Menten kinetics. Calibration time was short, typically 1.5 min per lactate standard. Furthermore, time drift was small, typically -1.3% to -3.3% per hour of in vivo use.

Book Review, Darold T. Barnum

RISK: Health, Safety & Environment (1990-2002)

Review of the following: HELENA CHMURA KRAEMER, EVALUATING MEDICAL TESTS: OBJECTIVE AND QUANTITATIVE GUIDELINES. (Sage Publications 1992). [295 pp.] Foreword A. John Rush, M.D. Acknowledgments, index, list of statistical notations, preface, references, and about the author. ISBN 0- 8039-4611-2 (cloth); 0-8039-4612-0 (paper). [Cloth $45.00, paper $22.50. 2455 Teller Road, Newbury Park CA 91320.1

A Rapid Concentration And Identification Technique For Human Malaria Infections Using A Mouse Model, Donald D. Barton

Loma Linda University Electronic Theses, Dissertations & Projects

Red blood cells infected with malaria parasites experience a change in density making them lighter (less dense). This paper reports a new, rapid diagnostic technique using this change in density in the infected red blood cell. It is not only easy to use, but it is also compatible with the technological conditions found where the malaria problem is most acute - in many developing countries of the world. A small sample of blood drawn from a simple finger stick can be concentrated and examined microscopically for malaria parasites within 10 minutes. The thick film slide preparation, presently used, takes a …

Group Comparability: A Multiattribute Utility Measurement Approach To The Use Of Random Assignment With Small Numbers Of Aggregated Units, C. Anderson Johnson, John W. Graham, Brian R. Flay, William B. Hansen, Linda M. Collins

CGU Faculty Publications and Research

It is not always possible, especially in large-scale evaluation research, to ensure that random assignment will produce groups that are comparable on any number of potentially important factors. Typically, gaining comparability has been achieved only at the expense of random assignment. A method is presented that allows multivariate comparability while making only minimal restrictions on randomization. The procedure is demonstrated in the context of assigning 63 aggregated units (schools) to 28 experimental and control conditions. Good comparability of groups for all primary main effects and interactions was verified for 15 individual variables.

An In Vivo Study Of Rabbit Oviductal Motility As Recorded Utilizing A Microminiature Extraluminal Force Transducer, William R. Anderson

MUSC Theses and Dissertations

A microminiature force transducer has been developed and used to record both acutely and chronically the motility of the rabbit reproductive tract. This device, which is comprised of two matched piezoresistive silicon sensors bonded to a titanium beam strip, is durable, physically stable, and highly sensitive to bending forces (gage factor, 140). The reproductive function of 26 rabbits in which two such devices were chronically implanted on the right isthmus was examined in detail. The animals in which these devices were implanted healed quickly with no evidence of infection or other pathological change. No alterations were noted between right (implanted) …

Characteristics Of The Recovery Of The Coenzyme A-Synthesizing Protein Complex From Saccharomyces Cerevisiae, Stanley Joseph Tarnowski Jr.

Theses and Dissertations (ETD)

A multienzyme complex contained in Bakers' yeast (Saccharomyces cerevisiae) which synthesizes CoA has been named the coenzyme A-synthesizing protein complex (CoA-SPC). The CoA-SPC has been shown to be insoluble in the crude Bakers' yeast cell lysate formed by exposing the yeast cell to ether and dry ice. Only after solubilization has this multienzyme complex been shown to catalyze the formation of bound dephospho-CoA utilizing the substrates adenosine triphosphate, D-pantothenic acid and L-cysteine. A low molecular weight component or components of the soluble fraction of the yeast cell and chloride ion appears to be responsible for the solubilization of CoA-SPC. This …

Clinical Photographic Analysis Of Dentofacial Midline Asymmetries, Larry A. Okmin

Loma Linda University Electronic Theses, Dissertations & Projects

Clinical diagnosis of dentofacial midline asymmetries has been difficult because of the problems in locating a reliable median sagittal reference plane, and because of the complexity and time involved in analysis. For these reasons, the clinician has generally resorted to direct visual observation in diagnosing midline discrepancies. A quick, precise, chairside method of dentofacial midline analysis would be of benefit to the orthodontist.

This study presented a clinical photographic method of dentofacial midline analysis and compared its precision with that of direct observation. The photographic method employed an Orthoscan Polaroid intraoral camera (Unitek) with a positioning device used to relate …

The Purification, Properties And Subunit Structure Of Glycerol Dehydrogenase, Michael James Barrett

Theses and Dissertations (ETD)

The inducible, NAD-linked glycerol dehydrogenase (E.C. 1.1.1.6) of a guanine requiring mutant of A. aerogenes has been purified to homogeneity. The molecular weight of the pure enzyme was found to be 3.4 x 10⁵ daltons. The sedimentation coefficient of the enzyme was 10.7 x 10^-13 sec.^-1. The diffusion constant was 3.07 x 10^-7 cm²/sec.

The partial specific volume calculated from the amino acid composition was 0.72 ml/g. The following kinetic parameters were determined; K_m glycerol, 2.4 x 10^-3 m, K_m NAD, 2.8 x 10^-4 M, K_m dihydroxyacetone, 5.1 …

Sex Determination By Cephalometry And Odontometry, Clair R. Hopkins Jr.

Loma Linda University Electronic Theses, Dissertations & Projects

Plaster casts of teeth and lateral cephalometric roentgenograms were studied to see with what degree of accuracy sex could be determined. The sample considered was made up of one hundred and forth-four individuals--50 males and 94 females--being treated in the Graduate Orthodontic Department of the Loma Linda University School of Dentistry. The age range for the boys was from 15 to 19 and for the girls, from 14 to 20. Data was obtained for the following variables from tracings of the roentgenograms and from the dental casts:

1. Glabello-occipital length
2. Articulate to nasion
3. The gonial angle of the mandible
4. Prosthion to …

An Odontometric Study Of Five Contemporary Western United States Indian And Alaskan Eskimo Groups, John A. Matis

Loma Linda University Electronic Theses, Dissertations & Projects

The morphologic characteristics of the oral cavity in five contemporary Western Indian and Alaskan Eskimo groups have been investigated by the use of study models of the dental archs. The sample consisted of 216 individuals, including 44 Navajos, 43 Apaches, 40 Papagos, 42 Pimas and 47 Alaskan Eskimos.

The first purpose of the study was to determine the extent of investigator error. This was accomplished by remeasuring many morphologic traits of the dentition in 125 Indians which had previously been measured by different investigators using the same study models. It was found that investigator error can be significant, even in …

A Cephalometric Comparison Of The Chamula, Mayo And Navajo Indians, Norman C. Bunker

Loma Linda University Electronic Theses, Dissertations & Projects

Lateral head x-rays were obtained on selected samples of 24 Chamula, 29 Mayo and 39 Navajo Indians for cephalometric comparison.

Cephalometric evaluation was carried out by means of the Bjork analysis. Mean values for each of the Indian groups were determined and compared with each other and with the mean values of a group of Swedish conscripts studied by Bjork. The mean values were statistically analyzed and and subjected to the Student's "t" test to determine the significant levels of differences.

Results revealed that in comparing the three Indian groups significant differences do appear. They are few and general concordance …

Effect Of 9 Α-Fluorohydrocortisone Acetate On Gastric And Salivary Electrolytes Of Normal Fasting Subjects, Ardis Stern Beckner

Loma Linda University Electronic Theses, Dissertations & Projects

The effect of 9α-FF on the Na:K ratio, chloride, and pH of saliva and gastric secretions, and on the total and free acid of gastric juice in normal human subjects was investigated. This study was designed to investigate whether conditions could be produced in the normal human subject similar to those present in patients with primary aldosteronism by using large doses of 9α-FF. August and others found a change in salivary electrolytes when cortisone, desoxycortisone, or ACTH were given to normal subjects. In these cases as in primary aldosteronism there was a decreased Na:K ratio and potassium excretion, with sodium …

Electron Micrographs Of A Cystine Urolith, John H. L. Watson

Henry Ford Hospital Medical Journal

No abstract provided.

Quantitative Sugar Estimations In Pleural Fluid - An Aid To Diagnosis, John E. Peterson

Medical Arts and Sciences: A Scientific Journal of the College of Medical Evangelists

In a study of 33 cases of serous effusion it would appear that determination of the sugar content of the pleural fluid may provide an early clue to the etiologic diagnosis.