Alternative and Complementary Medicine Commons^™

Homoeopathic Medicines Modulate Inflammatory Functions And Adhesion Receptor Expression In Human Blood Cells: An In Vitro Study, Nibedita Dalpati, Shubham Kumar Rai, Divya Singh, Shiba Prasad Dash, Sukanti S. Sarangi, Mahabahu Nayak, Pranita P. Sarangi

Indian Journal of Research in Homoeopathy

Background: Homoeopathic medicines are used extensively for the treatment of many human diseases and are shown to affect immune cell functions. However, our understanding of the immunomodulatory effects of such medicines and associated mechanisms of action remains limited. Objectives: The present study aims to investigate the immunomodulatory effects of Arsenic album, Rhus toxicodendron, Hepar sulphuris and Bryonia alba on lipopolysaccharide (LPS) induced peripheral blood neutrophils and monocytes. Materials and Methods: In this work, neutrophils and monocytes were treated with different homoeopathic dilutions of 30C potency separately, followed by stimulation with the LPS, to examine the immunomodulatory effects of these …

Mucocele Of Lower Lip Treated With Constitutional Homoeopathic Medicine Silicea – A Case Report, Uma Maheswari M.S, Sisir P R, Gopukumar S T

Indian Journal of Research in Homoeopathy

Introduction: A mucocele is a mucus-containing benign cystic lesion of the salivary gland. Based on the histological features, they are classified into two types, mucous retention cysts and mucous extravasation cysts. They appear in the minor salivary glands due to mechanical damage to the gland or its duct. The case study presented here is a detailed analysis of a 6-year-old male child affected by mucocele of the lower lip and its homoeopathic treatment and significance. Case Summary: A 6-year-old child presented with complaint of a swelling over the mucosa of the lower lip. Initially, the swelling was small, …

Recurrent Appendicitis Treated With The Homoeopathic Medicine Iris Tenax 30c: A Case Report, Vinitha Edavattath Ramanan, Shareena Cp

Indian Journal of Research in Homoeopathy

Introduction: The non-acute variants of appendicitis include recurrent, subacute, and chronic appendicitis, which are rarely diagnosed and remain subjects of case reports. The diagnosis is complex and is based on history, clinical examination, and an ultrasonogram or computed tomography. Unlike the acute variety, a surgical emergency, these cases do not require immediate surgery. In the present case, the patient had pain in the right lower quadrant (RLQ) of the abdomen in January 2021, which was relieved with conventional medications. However, the pain recurred after 2½ months and was diagnosed as recurrent appendicitis. Case Summary: This case of recurrent appendicitis was …

Post-Partum Depression Managed With Homoeopathic Cimicifuga Racemosa In One Week Of Inpatient Treatment: A Case Report, R. Bhuvaneswari, Neethu Raj

Indian Journal of Research in Homoeopathy

Introduction: Post-partum depression (PPD) is a disabling psychiatric disorder that has long-term effects on the mother and the baby. Because many people do not comply with antidepressant medication, there is a great need for alternative treatment options like homoeopathy that are less harmful. Case Summary: Here, we have presented the case report of a woman with PPD, who experienced guilt, depressed mood, suicidal thoughts, restlessness and auditory hallucination. Based on repertorial totality, Cimicifuga racemosa 200C was prescribed. The case was screened using the Edinburgh Postnatal Depression Scale. To assess the outcome of the treatment, the 17-item Hamilton depression rating scale …

Management Of Overt Hypothyroidism With Homoeopathic Medicine Iodium - An Evidence-Based Case Report, Bharti Wadhwa, Anamika Singh

Indian Journal of Research in Homoeopathy

Introduction: Hypothyroidism is a hypo-metabolic state resulting from inadequate secretion of thyroid hormones. It is the second most common endocrine disorder among women and a leading cause of menstrual abnormalities in all age groups, thereby affecting reproductive functions in females. Levothyroxine is the standard lifelong mode of treatment in conventional medicine. Case Summary: A 35-year-old hypothyroid female presented with menstrual irregularities. However, the physical general symptoms in this patient were contrary to the expected clinical presentation of the disease. Individualised homoeopathic medicine was selected for this patient, based on these peculiar symptoms and complete recovery was seen with the restoration …

Homoeopathy In Management Of Chronic Ischaemic Ulcer: An Evidence-Based Case Report, Jayabharathi Srinivasagam, Rohini S, Srinivas Govindarajulu, Tamil Selvi S

Indian Journal of Research in Homoeopathy

Introduction: Ischaemic or arterial ulcer occurs when there is an obstruction in the arterial supply to a particular part of the human body leading to necrosis. These are extremely painful types of chronic wounds. Treating arterial ulcers is a difficult task for the physician since supportive measures such as compression therapy and leg elevation are contraindicated. Surgical intervention is the ultimate approach to manage in conventional medicine. The homoeopathic system of medicine offers a wide range of medicines and a holistic approach to treat such cases non-invasively. Case Summary: A case of a 75-year-old woman who suffered from chronic ischaemic …

Management Of Erythrodermic Psoriasis With Individualised Homoeopathy: An Evidence-Based Case Report, Dastagiri P, Hafsa Muhammed

Indian Journal of Research in Homoeopathy

Introduction: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis, with an estimated prevalence among psoriatic patients ranging from 1% to 2.25%. It presents as erythema, oedema, pruritus, ill-defined psoriatic plaques, scaling, hair loss and occasionally exudative lesions and palmoplantar diffuse desquamation with nail changes ranging from mild pitting to severe onychodystrophy, more commonly involving the fingernails than the toenails. Case Summary: A 60-year-old male patient, already diagnosed with EP, presented with extensive involvement of body surface area (80–90%). He was treated with Hepar sulphur based on the acute totality, followed by Arsenicum sulphuratum rubrum starting from 30C …

Colloid Nodular Goitre Treated With Homoeopathic Medicine Natrum Muriaticum In Lm Potency: A Case Report, Suraia Parveen, Zeeshan Ahmed

Indian Journal of Research in Homoeopathy

Introduction: Colloid goitre is a common, benign lesion in the thyroid gland, involving a diffuse or nodular pattern. It is a clinical entity characterised by subsequent growth, structural or functional transformation of one or more areas within the normal thyroid tissue. A thyroid nodule can grow to be visible, which becomes a cosmetic concern for the patient.

Case Summary: A 32-year-old female presented with the complaint of swelling on the right side of her neck for the past 1½ years. The case was diagnosed by ultrasonography as a right-sided colloid nodular goitre with internal cystic degeneration. She was advised by …

Dare To Differ - A Doctor’S Quest For A Gentle Cure, Renu Mittal

Indian Journal of Research in Homoeopathy

Dare to Differ- A Doctor's Quest for a Gentle Cure

Research Highlights, Purnima Rani, Twinkle Goyal

Indian Journal of Research in Homoeopathy

Research highlights

Fundamentals Of Reporting A Case, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Clinical case reports form a fundamental component of the homoeopathic medical literature and are the most popular amongst readers. Case reports illustrate evidence-based classical or contemporary homoeopathic treatment strategies, diagnostics or rare or unusual diseases managed with homoeopathy. They also serve the purpose of raising awareness of important clinical issues amongst the homoeopathic fraternity. Our last case report special issue (Volume 16, Issue 2, April–June 2022) received more than 12,000 downloads within a year. This success has encouraged us to publish another case report special issue this year. Our journal has received 95 submissions in the form of case reports …

Embarking On The Journey Of Pharmacovigilance Of Homoeopathic Drugs, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Embarking on the journey of pharmacovigilance of homoeopathic drugs

Knowledge, Awareness, Attitude And Practice Of Indian Homoeopathic Physicians About Pharmacovigilance In Homoeopathy: A Web-Based Cross-Sectional Study, Rajib Purkait, Baidurjya Bhattacharjee, Abhiram Banerjee, Gurudev Choubey

Indian Journal of Research in Homoeopathy

Background: Pharmacovigilance (Pv) is the science and activities relating to detecting, assessing, understanding and preventing adverse effects or any other drug-related problems. The subject is essential for developing reliable information on the safety of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy medicines.

Objectives: This study explored the homoeopathic physicians’ knowledge, awareness, attitude and practice (KAAP) towards the Pv programme in homoeopathy.

Methods: An online cross-sectional survey was conducted among 274 Indian homoeopathic practitioners for 2 months. The study team developed the questionnaire in consultation with three subject experts and the same was circulated as a generated link among different …

Homoeopathy In The Management Of Generalised Anxiety Disorder: A Case Report, Karunakara Moorthi, Radhika P

Indian Journal of Research in Homoeopathy

Introduction: Generalised anxiety disorder (G.A.D.) is characterised by excessive, pervasive and uncontrollable worry. G.A.D. is a chronic and recurrent disorder with a low rate of remission with a considerable impact on quality of life. There is a scarcity of literature published on homoeopathy on G.A.D. This case report illustrates an improvement without recurrence of a G.A.D. case treated exclusively with homoeopathic medicine.

Case Summary: A 36-year-old man presented with anxiety about least trifles, easily irritable, palpitation, gastric disturbances, tension, excessive sweating, sleep disturbances and difficulty in concentration. After thorough case-taking, homoeopathic treatment with Lycopodium 200C and Sulphur 1000C led to …

Obviating Surgical Amputation Of Diabetic Gangrene Through Homoeopathy – A Case Report, Poojitha Ankerela, Sangeeta Belgavimath, Premalata Rotti

Indian Journal of Research in Homoeopathy

Introduction: Gangrene is defined as the decay or death of an organ or tissue due to a compromised blood supply. It is a perilous and fatal condition occurring most commonly due to diabetes. In general, people with diabetes have a significantly increased risk of lower extremity gangrene leading to amputation.

Case Summary: A 70-year-old woman presented with diabetic gangrene of her right leg and foot since 4 months. The patient complained of swelling and blackish discoloration of the right foot and leg with offensive discharging ulcers on the first and third toes. She was diagnosed with diabetic foot gangrene …

Good Clinical Practice Guidelines For Clinical Trials In Homoeopathy, Dastagiri P

Indian Journal of Research in Homoeopathy

Good Clinical Practice Guidelines for Clinical trials in Homoeopathy: Book Review

Research Highlights, Lalit Tyagi, Navita Bagdi

Indian Journal of Research in Homoeopathy

Research Highlights

Antioxidant And Cytotoxic Potential Of Potentized Preparation Of Cordyceps Sinensis In Vitro In Cancer Cell Lines, Vettrivel Arul, Rajamanickam Kandasamy, Mary Adharshna Sp

Indian Journal of Research in Homoeopathy

Background: The parasitic fungus Cordyceps sinensis (Ophiocordyceps sinensis) has been discovered in lepidopteran larvae, having known antitumor effects. Testing potentized Cordyceps sinensis in cancer cells could help broaden Homoeopathy cancer therapeutics.

Objectives: The objectives of the study were to evaluate the antioxidant and cytotoxicity activity of potentized preparation of Cordyceps sinensis in carcinoma cell-lines.

Methods: In this in vitro study, antioxidant activity was analyzed by the 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay and the dilution with more antioxidant potential was further analyzed for cytotoxicity, using 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on various carcinoma cell lines: Breast cancer cell line (MCF-7), liver cancer cell line (HePG2), …

A Randomised, Double-Blind, Placebo-Controlled And Parallel-Arm Trial To Assess The Effect Of Homoeopathic Medicines On Chronic Rhinosinusitis, Praveen Oberai, Subhash Kaushik, Sunil Ramteke, M N. Sinha, Sarabjit Sarkar, Kalpana Gautam, Arvind Kumar, Harleen Kaur, Raj Kumar Manchanda, Roja Varanasi

Indian Journal of Research in Homoeopathy

Background: Chronic rhinosinusitis (CRS) is a significant health problem impacting health related quality of life.

Objectives: This study assesses the efficacy of individualised homoeopathy (IH) in LM potency in CRS.

Methods: A randomised, double-blind and placebo-controlled trial on patients with CRS was undertaken at four institutes, from July 2012 to December 2013. Eligible participants were randomised to IH in LM-potencies (n = 60) or a similar placebo (n = 60). Primary outcome was change in the total symptoms score (TSS) (area under the curve [AUC]) and in sinus nasal outcome test 22 over 3 months. Intention-to-treat approach was used …

Can The Sweet Pills Restore The Smiles Of Autistic Children?, Deepthi Gilla, K.C. Muraleedharan

Indian Journal of Research in Homoeopathy

The second of April marks World Autism Awareness Day (WAAD), every year globally. WAAD was designated by the United Nations in 2007 to help end stigmatization and discrimination against those with Autism and their caregivers. It aims to raise understanding and awareness of this global health issue at all levels of society. The alarming increase in prevalence (1 in 100-WHO) and potentially lifelong disabling nature of the disorder demands awareness as early identification and intervention are pivotal in the management of Autism.

Research Highlights, Noopur Kumari, Babita Rani Kondle

Indian Journal of Research in Homoeopathy

Summary of the studies has been highlighted from Sep till Nov 2022.

Covid-19 Vaccination: Hesitancy, Side Effects And Homoeopathy, Subhash Kaushik

Indian Journal of Research in Homoeopathy

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Covid-19 Vaccines And Homoeopathy – An Integrative Review, Deepthi Gilla, S R Sreelakshmy, Bsj Raja Kumar

Indian Journal of Research in Homoeopathy

Background: The COVID-19 pandemic has brought millions of people at risk. Clinical trials of several known antiviral drugs and vaccines have been done. Homoeopathy is known to be effective in the prevention and treatment of infectious diseases as well as in overcoming some adverse effects of vaccination. Objectives: The objectives of this review were to identify the adverse effects of COVID-19 vaccination from the published literature and doing homoeopathic repertorisation to find out indicated remedies for alleviating the ill effects of COVID-19 vaccines. Methods: Published literature was searched for ‘Covid-19’, ‘Vaccination’ and ‘Adverse events’ in PubMed between …

Homoeopathy In Plantar Psoriasis: An Evidence-Based Case Report, Gr Kiranmayee Rompicherla, Hima Bindu Ponnam

Indian Journal of Research in Homoeopathy

Introduction: Plantar psoriasis is a variant of psoriasis and accounts for 3–4% of total cases of psoriasis. Psoriasis, an autoimmune and chronic inflammatory disease of the skin, can leave the patient in agony with its distressing infection episodes. The homoeopathic system of medicine offers a wide range of medicines that can have a beneficial role in managing cases of psoriasis as depicted in the previous studies. Case summary: A distinct case of plantar psoriasis treated with homoeopathic remedies of ultra-high dilution has been presented here. The evidence-based illustrations were done before and after the treatment and the periodical objective …

Homoeopathic Treatment Of A Diabetic Covid-19 Patient With The Complication Of Bronchitis And Pleural Effusion - A Case Report, Alok Ghosh, Sadia Kamal

Indian Journal of Research in Homoeopathy

Introduction: COVID-19 is a novel SARS-CoV-2 disease that has caused a worldwide pandemic. It is highly contagious and produces severe acute respiratory syndrome. Many homoeopathic medicines have been suggested for treatment of COVID cases and reports have also been published. Case Summary: The present case report is of a 61-year-old COVID-positive, male, presenting with complications such as bronchitis and pleural effusion. He was treated for COVID-19 with a suitable homoeopathic medicine, based on the totality of symptoms, while the patient continued his regular regime of conventional medicine for diabetes mellitus and hypertension. The indicated remedy led to immediate relief …

Scope Of Homoeopathy In The Treatment Of Depression: A Narrative Synthesis, Karunakara Moorthi, Radhika P, Manu Chandran, K.C. Muraleedharan

Indian Journal of Research in Homoeopathy

Background: Depression is a disorder of major public health importance, in terms of its prevalence and suffering, dysfunction, morbidity and economic burden. Depression is one of the most common conditions for which people seek homoeopathic treatment. Objective: This study is aimed to understand the scope of homoeopathy in depression based on the results of previous studies. Methods: A study was done to evince the scope of homoeopathic medicines in the treatment of depression. Searches were done in both general and specialised databases. The data were collected from peer-reviewed journals published between January 2001 and January 2021. Efforts …

Acknowledgement To Our Reviewers (2022), Ijrh Editorial Board

Indian Journal of Research in Homoeopathy

Indian Journal of Research in Homoeopathy editorial team duly acknowledges the following reviewers, who reviewed the articles in the year 2022. Their invaluable and timely efforts enabled a fair and rigorous peer review process. Also, the valued recommendations of the Editorial Advisory Board members are also deeply acknowledged.

Homoeopathy In The Management Of Chronic Kidney Disease – A Narrative Review, Supriya Singh, Varanasi Roja, Khushboo Garg, Nisha Sehrawat, Jyotika Bhatti, Abhijit Chakma

Indian Journal of Research in Homoeopathy

Background: Chronic kidney disease (CKD) is the third fastest-growing cause of death around the world and is projected to become the fifth most common cause of years of life lost worldwide by 2040.

Objective: This review was done to explore the strengths of homoeopathy in the management of CKD through pre-clinical, clinical and anecdotal evidence.

Methods: A search was made for homoeopathic management of CKD in PubMed, Central Council for Research in Homoeopathy e-library, AYUSH Research Portal, EMBASE and Google Scholar. The basic search terms included ‘Homoeopathy’ or ‘homoeopathic drugs’, ‘ESRD’, ‘CRF’, ‘CKD’ and ‘Bright’s disease’. No …

Polycystic Ovarian Syndrome With Endometrial Hyperplasia And Uterine Fibroids Treated With Homoeopathy: A Case Report, Vaishali Shinde

Indian Journal of Research in Homoeopathy

Introduction: Any circumstance that alters the balance of oestrogen and progesterone leads to excessive, prolonged estrogenic stimulation, or preventing the counteracting effects of progesterone causing various pathological conditions in the reproductive system, as a result. Women with polycystic ovarian syndrome (PCOS) have mostly anovulatory cycles and low serum progesterone levels. Endometrial hyperplasia is most often due to excess oestrogen without progesterone. The clinical significance of chronic oestrogen secretion is an increased risk of endometrial hyperplasia. A striking feature of uterine fibroids (UFs) is their dependency on the ovarian oestrogen and progesterone. Existing treatments are mostly directed at the symptoms …

Research Highlights, Shweta Singh, Pooja Kumari

Indian Journal of Research in Homoeopathy

Research Highlights