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Alternative and Complementary Medicine Commons™
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Full-Text Articles in Alternative and Complementary Medicine
The Effect Of Proprioceptive Neuromuscular Facilitation Stretching On Flexibility, Muscle Power, And Aerobic Fitness, Dustin Rex
Graduate Theses
Proprioceptive neuromuscular facilitation (PNF) is a commonly used stretching technique in rehabilitation and athletic competition. The most accepted benefit associated with PNF has been for increasing flexibility; however its definitive effect on muscle power and aerobic fitness remains controversial and relatively unknown. The purpose of this study was to determine the effect of prolonged use of PNF on flexibility at the hip, muscle power of the hamstring and aerobic capacity measured during submaximal exercise. Testing this required the participation of 10 adults split into two groups, who were tested for flexibility, muscle power, and aerobic capacity at three levels based …
Discovery Of Quinic Acid Derivatives As Oral Anti-Inflammatory Agents, Kui Zeng
Discovery Of Quinic Acid Derivatives As Oral Anti-Inflammatory Agents, Kui Zeng
Theses and Dissertations (ETD)
Quinic acid (QA) esters found in hot water extracts of Uncaria tomentosa (a.k.a. Cat’s claw) exert anti-inflammatory activity through mechanisms involving inhibition of the pro-inflammatory transcription factor nuclear factor kappa B (NF-κB). Herein, we described the synthesis and biological testing of novel QA derivatives. Inhibition of NF-κB was assessed using A549 (Type II alveolar epithelial-like) cells that stably express a secreted alkaline phosphatase (SEAP) reporter driven by an NF-κB response element. A549- NF-κB cells were stimulated with TNF-α (10 ng/mL) in the presence or absence of QA derivative for 18 hours followed by measurement of SEAP activity. Amide substitution at …