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Theses/Dissertations

Portland State University

Trauma centers

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Outcome Analysis Of Tranexamic Acid In Thromboembolic Complications And Coagulation Factors, Hunter A. Mccorkle Nov 2020

Outcome Analysis Of Tranexamic Acid In Thromboembolic Complications And Coagulation Factors, Hunter A. Mccorkle

University Honors Theses

Background: Tranexamic acid (TXA) is an antifibrinolytic used for controlling hemorrhaging in patients. It’s regular application in trauma centers could be vital in reducing all-cause mortality for hemorrhaging secondary to traumatic injury but there are still concerns about possible side effects and populations at greater risk of complications. The possible use of predictive measures such as thrombelastography (TEG) and conventional coagulation testing (CCT) in detecting early markers of TXA risks are still unconfirmed, and unfortunately there is a time restriction of 3 hours for TXA to be effective in reducing all-cause mortality.

Objective: Our objective is to observe outcomes of …