Medicine and Health Sciences Commons^™

Caloric Restriction, Aerobic Exercise Training And Soluble Lectin-Like Oxidized Ldl Receptor-1 Levels In Overweight And Obese Post-Menopausal Women, Tina E. Brinkley, Xuewen Wang, Noriaki Kume, Hirokazu Mitsuoka, Barbara J. Nicklas

Faculty Publications

Background—Elevated circulating levels of soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) have been observed in obese persons and are reduced by weight loss. However, it is not known if combining caloric restriction (CR) with exercise training is better in reducing sLOX-1 levels than CR alone.

Objective—We examined whether the addition of aerobic exercise to a weight loss intervention differentially affects sLOX-1 levels in 61 abdominally obese postmenopausal women randomly assigned to a CR only (n=22), CR + moderate-intensity exercise (n=22), or CR + vigorous intensity exercise (n=17) intervention for 20 weeks. The caloric deficit was ~2,800 kcal/week for …

Chronic Diseases: The Emerging Pandemic., Andre Terzic, Scott A. Waldman

Department of Pharmacology and Experimental Therapeutics Faculty Papers

According to the 2011 World Health Organization Global Status Report, of the 57 million annual global deaths – a staggering 36 million or over 63% are due to chronic diseases.¹ Four noncommunicable diseases - namely cardiovascular, cancer, diabetes, and chronic respiratory diseases - emerge as the leading cause of mortality in the world, accounting respectively for 17, 7.6, 4.2, and 1.3 million deaths based on the latest available global epidemiology data. By 2020, global deaths due to chronic diseases are projected to worsen by at least 15 to 20%. It is estimated that the four major noncommunicable diseases will …

Acute Effects Of A Selective Cannabinoid-2 Receptor Agonist On Neuroinflammation In A Model Of Traumatic Brain Injury., Melanie B Elliott, Ronald F Tuma, Peter S Amenta, Mary F Barbe, Jack I Jallo

Department of Neurosurgery Faculty Papers

Proposed therapeutic strategies for attenuating secondary traumatic brain injury (TBI) include modulation of acute neuroimmune responses. The goal of this study was to examine the acute effects of cannabinoid-2 receptor (CB(2)R) modulation on behavioral deficits, cerebral edema, perivascular substance P, and macrophage/microglial activation in a murine model of TBI. Thirty male C57BL/6 mice underwent sham surgery, or cortical contusion impact injury (CCI). CCI mice received vehicle or the CB(2)R agonist 0-1966 at 1 and 24 h after injury. Performance on the rotarod, forelimb cylinder, and open-field tests were evaluated before and at 48 h after sham or CCI surgery. Cerebral …

Trends Over 5 Decades In U.S. Occupation-Related Physical Activity And Their Associations With Obesity, Timothy S. Church, Diana M. Thomas, Catrine Tudor-Locke, Peter T. Katzmarzyk, Conrad P. Earnest, Ruben Q. Rodarte, Corby K. Martin, Steven N. Blair, Claude Bouchard

Faculty Publications

Background: The true causes of the obesity epidemic are not well understood and there are few longitudinal population-based data published examining this issue. The objective of this analysis was to examine trends in occupational physical activity during the past 5 decades and explore how these trends relate to concurrent changes in body weight in the U.S.

Methodology/Principle Findings: Analysis of energy expenditure for occupations in U.S. private industry since 1960 using data from the U.S. Bureau of Labor Statistics. Mean body weight was derived from the U.S. National Health and Nutrition Examination Surveys (NHANES). In the early 1960's almost half …

Examining Activity Levels And Motor Proficiency: A Comparison Of Children Who Are Overweight And At A Healthy Weight To Their Parents And Peers, Aaron Copeland, Maresa Madsen, Riley Phelps, Brandon Richards

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: The purpose of this study was to examine relationships and differences between motor proficiency, activity level, and parental activity level in children who are at a healthy weight and children who are overweight or obese.

Methods: Forty-four children (26 children at a healthy weight and 18 children who were overweight or obese) between the ages of 8-16 (BMI: 14.3-43.6 kg/m2) and 36 parents (BMI: 18.1-44.7) participated in this study. Children and parents wore StepWatch activity monitors (SAM) to measure activity levels over a 72 hour period. Tests reflecting several determinants of motor performance were also administered to …

Effects Of Exercise On Brain Activation In Response To Visual Food Cues, Laura Hackett

Kinesiology and Public Health

No abstract provided.

Fit Into College: A Program To Improve Physical Activity And Dietary Intake Lifestyles Among College Students, Robert V. Topp, Jean S. Edward, S. Lee Ridner, Dean E. Jacks, Karen Newton, Patricia Keiffner, Deborah Woodall, Kathleen P. Conte

College of Nursing Faculty Research and Publications

The purpose of this study was to determine whether a 10-week program could improve physical activity, physical fitness, body weight, dietary intake, and perceptions of exercise and diet among college 30 healthy college freshmen. Outcomes were measured at baseline, and following the 10-week program. The weekly sessions incorporated constructs of the Transtheoretical Model of Health Behavior Change and were administered by fitness interns who were junior or senior college students enrolled in health-related majors. The participants presented with low physical activity, physical fitness, and poor dietary intake, and 50% were overweight/obese (BMI > 25). Participants demonstrated gains in their physical fitness …

Validation Of The Actical Activity Monitor In Middle-Aged And Older Adults, Steven P. Hooker, Anna Feeney, Brent E. Hutto, Karin A. Pfeiffer, Kerry Mciver, Daniel P. Heil, John E. Vena, Michael J. Lamonte, Steven N. Blair

Faculty Publications

Purpose: This study was designed to validate the Actical activity monitor in middle-aged and older adults of varying body composition to develop accelerometer thresholds to distinguish between light and moderate intensity physical activity (PA).

Methods: Nonobese 45 to 64 yr (N = 29), obese 45 to 64 yr (N = 21), and ≥65 yr (N = 23; varying body composition) participants completed laboratory-based sitting, household, and locomotive activities while wearing an Actical monitor and a portable metabolic measurement system. Non-linear regression analysis was used to identify activity count (AC) cut-points to differentiate between light intensity (<3 METs) and moderate intensity (≥3 METs) PA.

Results: Using group-specific algorithms, …

Combating Childhood Obesity In California, Janelle Borelli

Social Sciences

Childhood obesity has become a major problem in Corporate America.  Our youth’s health is at risk, the statistics are alarming, and childhood obesity is largely preventable.  In order to solve the childhood obesity epidemic, government action, both state and federal, needs to be taken by passing nutrition standard laws.  Also, the built environment should support an active lifestyle rather than one based on fast food and lack of exercise.  Families should adopt a healthy lifestyle including having adequate fruits and vegetables at home along with exercising daily.

Get Healthy Philly: Policy Change To Promote Healthy Eating, Active Living, And Tobacco Control, Laura Kimberly Msw, Mbe

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Parental Perceptions Of The Rural School’S Role In Addressing Childhood Obesity, Ann M. Stalter, Mary Beth Kaylor, Jessica D. Steinke, Rosanta M. Barker

Nursing Faculty Publications

This study employed cross-sectional, descriptive design with convenience sampling to explore rural parent perceptions of child obesity, use of Body Mass Index (BMI) in schools, preferences for receipt of BMI information and, the rural school’s role in obesity prevention/treatment. The survey “Parental Perceptions of BMI and Obesity in the School-Age Child” was used. Of the 183 surveys distributed, 65 were returned (35.5%). Fifty-five percentage of parents were in agreement of school-based BMI screening. Fifty-four percentage of parents selected a combination of ways to receive BMI information (letter from school nurse, face-to-face conference with nurse, or via report card). Few parents …

Sleep Duration, Sleep Regularity, Body Weight, And Metabolic Homeostasis In School-Aged Children, Karen Spruyt, Dennis L. Molfese, David Gozal

Center for Brain, Biology, and Behavior: Faculty Publications

OBJECTIVE: The goal was to explore the effects of duration and regularity of sleep schedules on BMI and the impact on metabolic regulation in children.

METHODS: Sleep patterns of 308 community-recruited children 4 to 10 years of age were assessed with wrist actigraphs for 1 week in a cross-sectional study, along with BMI assessment. Fasting morning plasma levels of glucose, insulin, lipids, and high-sensitivity C-reactive protein also were measured for a subsample.

RESULTS: Children slept 8 hours per night, on average, regardless of their weight categorization. A nonlinear trend between sleep and weight emerged. For obese children, …

Prevalence Of Metabolic Abnormalities In Children With Varying Degrees Of Obesity, Leah Sabato

Master of Public Health Program Student Publications

As the prevalence of obesity among children has risen, metabolic syndrome, a cluster of abnormalities which includes obesity, altered glucose metabolism, hypertension, and dyslipidemia, has increasingly become recognized in the pediatric population. Metabolic syndrome has been studied extensively in adults, and there is increasing interest to understand the condition in adolescents; however, studies of metabolic syndrome in younger children are limited. The purpose of this study is to examine the prevalence of metabolic syndrome and its individual components among children aged 6-10 years. Demographic, anthropometric, and biochemical data were gathered retrospectively from the medical records of 222 obese children aged …

The Association Between Neighborhood Walkability, Type 2 Diabetes, And Socioeconomic Status In Residents Of Eight Ohio Counties, Dawn L. Ebron

Master of Public Health Program Student Publications

Objective: Regular physical activity is beneficial in preventing type 2 diabetes. Walking, either for recreation or to travel to a destination, is an inexpensive way to meet physical activity guidelines. Disadvantaged populations with low socioeconomic status (SES) have a higher prevalence of type 2 diabetes and are more likely to live in unwalkable neighborhood. The purpose of this study was to determine the association between SES and neighborhood walkability in eight Ohio counties with highest prevalence of type 2 diabetes in the state.

Methods: Using data from the 2010 Ohio Behavioral Risk Factor Surveillance System (BRFSS) survey and Walk Score …

Web-Based Interventions For Weight Loss And Weight Maintenance Among Rural Midlife And Older Women: Protocol For A Randomized Controlled Trial., Patricia A. Hageman, Carol H. Pullen, Melody Hertzog, Linda S, Boeckner, Susan Noble Walker

Journal Articles: Physical Therapy

BACKGROUND: Weight loss is challenging and maintenance of weight loss is problematic among midlife and older rural women. Finding effective interventions using innovative delivery methods that can reach underserved and vulnerable populations of overweight and obese rural women is a public health challenge.

METHODS/DESIGN: This Women Weigh-In for Wellness (The WWW study) randomized-controlled trial is designed to compare the effectiveness of theory-based behavior-change interventions using (1) website only, (2) website with peer-led support, or (3) website with professional email-counseling to facilitate initial weight loss (baseline to 6 months), guided continuing weight loss and maintenance (7-18 months) and self-directed weight maintenance …

Parental Perception Of Childhood Obesity And The School's Role On Prevention And Interventions In Childhood Obesity, Monique Jones

Nursing Theses and Capstone Projects

Childhood obesity is a major health crisis that is becoming an epidemic among children and adolescents. Interventions must begin early and focus on prevention strategies to achieve the goal of increasing quality years of life for today's children and families. Parents with children in a local after school Boys & Girls club were surveyed regarding their perception of childhood obesity, the causes of childhood obesity, and the school's role in the prevention and treatment of childhood obesity. More than 90% of the participants identified inactivity, poor eating behavior, eating too much, and lack of money to buy nutritious foods as …

Decomposing The Intergenerational Disparity In Income And Obesity, Qi Zhang, Buhong Zheng, Ning Zhang, Youfa Wang

Community & Environmental Health Faculty Publications

Intergenerational disparity in income and health violates the norm of equal opportunity and deserves the attention of researchers and policy makers. To understand changes in intergenerational disparity, we created the intergenerational mobility index (IMI), which can simultaneously measure changes in income rankings and in health outcomes across two generations. We selected obesity as one health outcome to illustrate the application of IMI due to its severe health and financial consequences for society and the significant changes in the distribution of obesity across income groups. Although obesity has increased in all income groups in the last four decades, higher income groups …

The Composite First Person Narrative: Texture, Structure, And Meaning In Writing Phenomenological Descriptions, Marcia Stanley Wertz, Marcianna Nosek, Susan Mcniesh, Elizabeth Marlow

Nursing and Health Professions Faculty Research and Publications

This paper illustrates the use of composite first person narrative interpretive methods, as described by Todres, across a range of phenomena. This methodology introduces texture into the presently understood structures of phenomena and thereby creates new understandings of the phenomenon, bringing about a form of understanding that is relationally alive that contributes to improved caring practices. The method is influenced by the work of Gendlin, Heidegger, van Manen, Gadamer, and Merleau-Ponty. The method’s applicability to different research topics is demonstrated through the composite narratives of nursing students learning nursing practice in an accelerated and condensed program, obese female adolescents attempting …

Assessment And Management Of Adult Obesity In A Primary Care Practice, Sherry M. Adkins

Master of Public Health Program Student Publications

Purpose: The purpose of this project was to describe primary care physician adherence to National Heart Lung and Blood Institute (NHLBI) Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults (1998) and to explore patient characteristics associated with physician assessment and management behaviors. Patient characteristics included age, sex, race, BMI, associated disease risk, and Medicaid coverage.

Methods: A chart abstraction of 99 randomly selected adult patients with at least one visit to a particular primary care practice during a 12-month period was completed. Patients were not pregnant during the year of review, and had a …

The Influence Of School Eating Environment On Children's Eating Behaviors: An Examination Of The Snda-Iii, Sabrina M. Neeley

Master of Public Health Program Student Publications

The prevalence of childhood overweight and obesity in the United States has prompted researchers to examine the factors that contribute to children’s food choices and consumption. Schools provide ample opportunities to teach children healthy eating habits, as well as create eating environments that are conducive to healthy eating behaviors. The National School Lunch Program (NSLP) provides federally assisted meals to millions of children every day and the assessment of the NSLP provides an opportunity to examine the school-eating environment. Hierarchical and logistic modeling of the SNDA-III, the USDA assessment of the NSLP, was conducted to determine relationships between environmental factors …

The Effects Of Racially-Motivated Emotional Arousal On The Eating Behaviors Of African American Women, Lenwood W. Hayman

Wayne State University Dissertations

Disparities between African Americans and Caucasians remain vast across a wide variety of health indicators. Chronic stress has been identified as a risk factor for a variety of chronic illnesses and poor health outcomes. One type of chronic stress that has been linked to health disparities is the stress associated with experiences of racial discrimination. The stress African Americans encounter as a result of their racist experiences contributes to a chronic elevation of their physiological stress response. In addition to stress, a major risk factor for coronary heart disease and diabetes is obesity, which has been established as a major …

Obesity And Cancer Screening According To Race And Gender., Heather Bittner Fagan, Richard Wender, Ronald E Myers, Nicholas Petrelli

Department of Family & Community Medicine Faculty Papers

The relationship between obesity and cancer screening varies by screening test, race, and gender. Most studies on cervical cancer screening found a negative association between increasing weight and screening, and this negative association was most consistent in white women. Recent literature on mammography reports no association with weight. However, some studies show a negative association in white, but not black, women. In contrast, obese/overweight men reported higher rates of prostate-specific antigen (PSA) testing. Comparison of prostate cancer screening, mammography, and Pap smears implies a gender difference in the relationship between screening behavior and weight. In colorectal cancer (CRC) screening, the …

The Role Of Policy And The Built Environment On Children's In-School Physical Activity In The Mississippi Delta, Abigail Gamble

Electronic Theses and Dissertations

School environments provide an ideal setting for children to develop and adopt active living behaviors as a way of life. The primary purpose of this investigation was to describe state, district and school level policy regarding in-school physical activity, the school built environment and in-school physical activity of children ages 6 through 11 years in the Mississippi delta. A mixed-methods approach was used to garner a rich understanding of how current policy and the built environment influence in-school physical activity and weight status. Eleven public schools in three districts representing two counties in the Mississippi delta participated in this investigation. …

Prevalence Of Obesity Among Head Start Preschoolers In Western Ohio, Angela Sims

Master of Public Health Program Student Publications

Objective: The intent of this study was to examine low income Head Start overweight and obese preschoolers, ages 3-5, in 8 western Ohio counties. Variables of interest included: obesity status, rural versus metropolitan location, home versus center-based Head Start, and access to physicians.

Methods: Data was collected retrospectively from the host Head Start site located in Piqua, Ohio. All Head Start enrolled preschoolers (N=1,181) ages 3 to 5 within the 8 western Ohio counties and 43 programs were studied. All children were considered of low income based on their acceptance into the Head Start program.

The data was retrieved from …

The Role Of Ghrelin And Leptin In Obesity: Is Exogenous Administration Of These Hormones A Possible Drug Therapy?, Peri Eckstein

The Science Journal of the Lander College of Arts and Sciences

Ghrelin and leptin are two hormones that have been recognized to have a major influence on energy balance. Leptin is a mediator of long term regulation of energy balance, suppressing food intake and thereby inducing weight loss. Ghrelin, on the other hand, is a fast acting hormone, playing a role in meal initiation. As a growing number of people suffer from obesity, understanding the mechanisms by which various hormones and neurotransmitters influence energy balance has been a subject of intense research. This paper provides background on leptin and ghrelin hormones, their role in food intake and body weight in humans, …

Anthropometric Measurements And Body Composition Analysis Of Obese Adolescents With And Without Metabolic Syndrome, Deni̇z Nazi̇re Çağdaş Ayvaz, Fatma Ni̇şanci Kilinç, Feyza Ayşenur Paç, Erman Çakal

Turkish Journal of Medical Sciences

Obesity and risk of metabolic syndrome (MS) are rapidly increasing in children. Therefore, criteria for MS were aimed to be evaluated in obese children (OC). Materials and methods: Anthropometric indices and body composition (bioimpedance) analysis (BIA) were compared in 32 obese and 32 normal-weight children. Biochemical parameters were evaluated in OC. Results of OC with/without MS were compared. Results: Subscapular skinfold thickness (SST) was more sensitive and specific than triceps skinfold thickness in the diagnosis of obesity. According to BIA basal metabolism rate, fat mass (FM), FM%, and FM index were higher, while impedance, FFM%, fat-free-mass (FFM) index, and total-body-water% …

Evaluation Of The Effectiveness Of An Intervention Program On Preventing Childhood Obesity In Denizli, Turkey, Özgür Sevi̇nç, Ali̇ İhsan Bozkurt, Mehmet Gündoğdu, Ümmühan Baş Aslan, Bülent Ağbuğa, Şehmus Aslan, Emel Di̇kbaş, Zeli̇ha Gökçe

Turkish Journal of Medical Sciences

To determine the efficiency of 2 different intervention programs (healthy nutrition education and/or physical activity programs) for preventing the obesity of primary school students. Materials and methods: Selected were 6 schools, making 3 groups, from all primary schools in Denizli with the half-day education system. Each group was composed of 2 schools. The groups were randomly divided into intervention group 1, intervention group 2, and the control group. The body mass index (BMI) levels of the students in all of the groups were calculated. Both the physical activity and healthy nutrition programs were applied to intervention group 1, and only …

Is Liraglutide Safe And Effective As A Monotherapy For The Treatment Of Obesity In Type 2 Diabetics And Healthy Individuals?, Erica Sheeran

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic review is to determine whether or not liraglutide is safe and effective as a monotherapy for the treatment of obesity in type 2 diabetics and healthy individuals.

Does Caffeine Consumption Effect Exercise Performance In Healthy Adults?, Meaghan E. Jones

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this systematic review is to determine whether or not caffeine ingestion prior to exercise effects exercise performance in healthy adults.

Is Growth Hormone An Effective Adjunct To Standard Treatment Regimens For Promoting Fat Mass Loss And Retention Of Lean Body Mass In The Treatment Of Obesity?, J. Caleb Henson

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this systematic review is to determine whether growth hormone is an effective adjunct in the treatment of obesity for promoting fat loss while retaining lean body mass.