Medicine and Health Sciences Commons^™

A Spoonful Of Sugar, Natali Bode

Tredway Library Prize for First-Year Research

No abstract provided.

The Effects Of Xanthigen Supplementation On Body Weight, Resting Energy Expenditure, And Body Composition In An Obese Population, Lisa Knecht

Honors Theses

Since obesity is a significant problem that is facing the American people, there has been great interest in trying to develop a successful health supplement to help counteract the effects of obesity. Xanthigen is a new supplement composed of brown seaweed extract and pomegranate seed oil and is theorized to increase resting energy expenditure and decrease BMI and body fat. This study involved a 16‐week supplementation protocol to examine the effects of Xanthigen supplementation on an obese population in the Mississippi area. Testing of resting energy expenditure, BMI, and body fat percentage took place every four weeks for 16 weeks. …

The Effects Of Xanthigentm Supplementation On Body Composition, Serum Markers Of The Metabolic Syndrome, And Hepaptic Enzyme Levels In An Obese Population, Emily Buras

Honors Theses

XanthigenTM [100 mg brown seaweed extract (0.8 % fucoxanthin) and 100 mg pomegranate seed oil (70 % punicic acid)] has been shown to significantly reduce body fat, liver fat, and improve serum markers of liver function in obese females. Twenty-nine participants were matched for age, gender, and body fat percentage and randomized into either a XanthigenTM group or a placebo group. For 16-weeks, participants were asked to consume a reduced calorie diet while supplementing their diet with their respective pills three times per day. Data were analyzed using multivariate ANOVA with repeated measures and presented as mean ± standard deviation. …

Obesity Trends In Head Start Preschoolers, Anna Sanders

Honors Theses

The purpose of this natural comparative study is to see if changes in diet, education, and activity made in a South Mississippi Head Start (HS) preschool from Fall 2007 through Fall 2010 made any changes in the Body Mass Index (BMI) trends in two cohorts of low-income African American 3-year-olds. Cohort 1 BMI trends were measured in Fall 2006 and Spring 2007, before major HS changes in diet, education and activity were made (pre-treatment), and Cohort 2 was measured in Fall 2010 and Spring 2011, after major changes were made (post-treatment).

The Effect Of Socioeconomic Status On Local School Wellness Policy Implementation In Mississippi Public Schools, Rebecca Masters

Honors Theses

In recent years, rates of overweight and obesity have increased dramatically in America due to nutritionally poor diets and more sedentary lifestyles. Research has shown that obesity is a risk factor for numerous other conditions such as stroke, heart disease, cancer, type 2 diabetes, and sleep apnea. Unfortunately, overweight and obesity do not only affect the adults in our nation. Rates of overweight and obesity have also increased among American children. Approximately 17% of American children are obese, which is three times the rate of 1980 (Menifield, Doty, & Fletcher, 2008). In order to improve the overall health of America’s …

Dna Methylation Arrays As Surrogate Measures Of Cell Mixture Distribution, Eugene Houseman, William P. Accomando, Devin C. Koestler, Brock C. Christensen, Carmen J. Marsit

Dartmouth Scholarship

There has been a long-standing need in biomedical research for a method that quantifies the normally mixed composition of leukocytes beyond what is possible by simple histological or flow cytometric assessments. The latter is restricted by the labile nature of protein epitopes, requirements for cell processing, and timely cell analysis. In a diverse array of diseases and following numerous immune-toxic exposures, leukocyte composition will critically inform the underlying immuno-biology to most chronic medical conditions. Emerging research demonstrates that DNA methylation is responsible for cellular differentiation, and when measured in whole peripheral blood, serves to distinguish cancer cases from controls.

Impact Of Adiposity Status On The Association Of Regular Statin Use And Increased Number Of Aberrant Crypt Foci, Homaira Rasool

Master's Theses

INTRODUCTION: While animal studies consistently show a preventive role of statin use in colon cancer development, evidence from human studies is conflicting with recent reports suggesting an increased risk of aberrant crypt foci and adenoma. We hypothesize that insufficient control of confounding due to indication bias for prescribing of statins, particularly obesity-induced physiologic dysregulation, might partly explain discrepant results. METHODS: We analyzed data from patients receiving standard colonoscopy at the Colon Cancer Prevention Program of the University of Connecticut Health Center, which was followed by chromoendoscopy for ACF detection. ACF number was categorized at low (RESULTS: Participants who reported regular …

A Study Of The Link Between Partial Sleep Deprivation And Obesity, Jennifer Pacheco

Honors College Theses

Obesity has become a major health problem with increasing prevalence and is related to multiple medical consequences, such as increased risk for diabetes, heart disease, arthritis, and cancer (Hasler et al., 2004). Due to the limited availability of effective treatment of weight problems, it is necessary to identify potential risk factors for obesity. One factor that has received increased attention is chronic partial sleep deprivation (<7 hours of sleep a night). The decrease in average sleep duration over the past three to four decades has occurred simultaneously with the increase in the prevalence of obesity. Chronic partial sleep deprivation could be a possible risk factor for obesity, but current understanding of the processes linking sleep deprivation to obesity is incomplete. The research will focus on examining the possible pathways through which partial sleep deprivation contributes to the development of obesity: alterations in metabolic pathways and waking behavior, including eating behavior and physical inactivity. The hypothesis behind the proposed study is that increasing sleep duration in obese individuals who experience partial sleep deprivation will lead to a decreased BMI. Research addressing the possible pathways and targeting the amount of sleep will benefit individuals in preventing and/or treating obesity.

European Union Food Law Update, Emilie Majster

Journal of Food Law & Policy

Nutrition is increasingly important in both the European Union (EU) and in global food-related policy making. Governments, which up until recently have focused on regulating food products based on a food safety perspective, are now turning to regulate from a nutritional aspect.

Association Among Obesity-Related Anthropometric Phenotypes: Analyzing Genetic And Environmental Contribution, Aline Jelenkovic, Esther Rebato

Human Biology Open Access Pre-Prints

Obesity has become a public health and policy problem in many parts of the world. Epidemiological and population studies in this field are usually based on different anthropometric measures, however, common genetic and environmental factors between these phenotypes have been scarcely studied. The objective of this work is to assess the strength of these factors on the covariation among a large set of obesity-related traits. The subject group consisted of 533 nuclear families living in the Greater Bilbao (Spain), and included 1702 individuals aged 2-61 years. Detailed anthropometric measurements (stature, breadths, circumferences and skinfolds) were carried out in each subject. …

Polycystic Ovary Syndrome: Pathogenesis, Health Consequences, And Treatment Of Pcos In Relation To Insulin Resistance, Danielle Bernier

Honors Theses and Capstones

The purpose of this paper is to present a review of the current research on polycystic ovary syndrome (PCOS). PCOS is one of the most common endocrine disorders in women of reproductive age, affecting 5-10% of the population. Despite its prevalence, PCOS remains largely under unknown. This review has been broken down into two separate chapters. The first is the pathogenesis and related health consequences of PCOS. This chapter focuses on the diagnosis of PCOS as well as the prevalence and incidence of the disease. It then delves into the pathogenesis with a focus on genetics, obesity, insulin resistance and …

Electrocardiographic Abnormalities Among Mexican Americans: Correlations With Diabetes, Obesity, And The Metabolic Syndrome, Saulette R. Queen, Beverly Smulevitz, Anne R. Rentfro, Kristina Vatcheva, David D. Mcpherson, Susan P. Fisher-Hoch, Joseph B. Mccormick, Susan T. Laing

School of Mathematical & Statistical Sciences Faculty Publications

Background: Resting ischemic electrocardiographic abnormalities have been associated with cardiovascular mortality. Simple markers of abnormal autonomic tone have also been associated with diabetes, obesity, and the metabolic syndrome in some populations. Data on these electrocardiographic abnormalities and correlations with coronary risk factors are lacking among Mexican Americans wherein these conditions are prevalent.

Objective: This study aimed to evaluate the prevalent resting electrocardiographic abnormalities among community-dwelling Mexican Americans, and correlate these findings with coronary risk factors, particularly diabetes, obesity, and the metabolic syndrome.

Methods: Study subjects (n=1280) were drawn from the Cameron County Hispanic Cohort comprised of community-dwelling Mexican Americans living …

Worksite Weight Loss Intervention For Employees In Stressful Workplaces: A Pilot Study And Baseline Survey Indicators Of Success, Pouran D. Faghri, Valerie B. Duffy, Nicole R. Benson, Martin G. Cherniack

UCHC Articles - Research

Statement of problem: Correctional facilities are stressful, unhealthy and dangerous working environments, which increase the risk of chronic diseases and a shortened lifespan for employees, particularly corrections officers. The need exists for effective worksite interventions to lower chronic disease risk and improve health of correctional employees. Objective: The primary aim was to pilot test eight-week worksite nutrition and physical activity educationalintervention for correctional employees and to determine baseline indicators of weight loss success. Methods: Twenty overweight/obese volunteer employees were recruited by convenience sampling. Educational material was tailored to baseline responses on diet and physical activity knowledge, preferences, and behaviors. Adiposity …

Dog Ownership During Pregnancy, Maternal Activity, And Obesity: A Cross-Sectional Study, Carri Westgarth, Jihong Liu, Jon Heron, Andrew R. Ness, Peter Bundred, Rosalind M. Gaskell, Alexander J. German, Sandra Mccune, Susan Dawson

Faculty Publications

The Avon Longitudinal Study of Parents and Children (ALSPAC) is an observational study of 14273 UK pregnant singleton mothers in 1990/1991. We examined outcomes of self report of strenuous activity (hours per week) at 18 and 32 weeks of gestation, hours spent in leisure-time physical activities and types, and pre-pregnancy body mass index (BMI); overweight status was defined as pre-pregnancy BMI$25 and obesity BMI$30. Pet ownership and activity data were reported for 11,466 mothers. Twenty-five percent of mothers owned at least one dog. There was a positive relationship between participation in activity at least once a week and dog ownership …

Research Brief: "Bmi Trajectory Groups In Veterans Of The Iraq And Afghanistan Wars", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about obesity rates among OEF/OIF veterans and how race, education level, gender, and use of the VA play a role in obesity rates. For practice and policy, a fitness education program should be implemented by the VA to help lower obesity rates since obesity can cause more serious health problems. Suggestions for future research include expanding the study to involve veterans from other military eras and expanding the study to look at more risks associated with obesity.

Childhood Obesity And Restrictions Of Parental Liberty. A Response To "Paternalism, Obesity, And Tolerable Levels Of Risk", Kristin Voigt

Democracy & Education

This paper responds to Michael Merry’s recent contribution on childhood obesity. Merry’s analysis highlights the difficulties in finding an appropriate balance between children’s and parents’ interests in antiobesity interventions and emphasizes the importance of weight stigma and its effects on the obesity debate. He concludes by recommending both a greater focus on policies that address society's contribution to childhood obesity and a greater involvement of obese individuals in the policy debate. This response focuses on three points. First, a more explicit recognition of parents’ interests can support the case for the kinds of policies Merry has in mind. Second, while …

Paternalism, Obesity, And Tolerable Levels Of Risk, Michael S. Merry

Democracy & Education

In this article the author examines the relationship between paternalism and childhood obesity. In particular he examines the risks of paternalistic intervention in order to prevent or curtail the occurrence of obesity among young children.

Kentucky Worksite Wellness Tax Credit: A Health Impact Assessment, Cecilia M. Watkins, T. Lovely

Public Health Faculty Publications

The purpose of the assessment was to evaluate the potential effects of a worksite wellness tax credit on three main areas of concern for Kentucky: (!) nutrition, physical activity and obesity levels of children whose parents receive Worksite Wellness services, (2) jobs and (3) social cohesion.

Health Enhancing Policies And Environments In Select Montgomery County Senior Centers, Stacey L. Gardner

Master of Public Health Program Student Publications

As the baby boomer generation reaches elderly status, healthcare expenditures in the United States continue to rise. Contributing to healthcare costs is the high prevalence of chronic diseases caused by unhealthy habits of Americans such as tobacco use, lack of physical activity, and consumption of a poor diet. Many chronic diseases can be prevented by engaging in healthier behaviors. Communities and organizations can shift social norms and affect behaviors through policy intervention and environmental strategies. The purpose of this study was to describe policies and environments that foster healthy lifestyles in select senior centers in Montgomery County, Ohio. Specifically, this …

Empiric Guideline-Recommended Weight-Based Vancomycin Dosing And Mortality In Methicillin-Resistant Staphylococcus Aureus Bacteremia: A Retrospective Cohort Study, Ronald G. Hall Ii, Christopher A. Giuliano, Krystal K. Haase, Kathleen A. Hazlewood, Chistopher R. Frei, Nicolas A. Forcade, Sara D. Brouse, Todd Bell, Roger J. Bedimo, Carlos A. Alvarez

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

No studies have evaluated the effect of guideline-recommended weight-based dosing on in-hospital mortality of patients with methicillin-resistant Staphylococcus aureus bacteremia.

Methods

This was a multicenter, retrospective, cohort study of patients with methicillin-resistant Staphylococcus aureus bacteremia receiving at least 48 hours of empiric vancomycin therapy between 01/07/2002 and 30/06/2008. We compared in-hospital mortality for patients treated empirically with weight-based, guideline-recommended vancomycin doses (at least 15 mg/kg/dose) to those treated with less than 15 mg/kg/dose. We used a general linear mixed multivariable model analysis with variables identified a priori through a conceptual framework based on the literature.

Results

A total …

Associations Of Cardiorespiratory Fitness And Fatness With Metabolic Syndrome In Rural Women With Prehypertension., Patricia A. Hageman, Carol H. Pullen, Melody A. Hertzog, Linda S. Boeckner, Susan Noble Walker

Journal Articles: Physical Therapy

BACKGROUND: This study investigated the associations of fitness and fatness with metabolic syndrome in rural women, part of a recognized US health disparities group.

METHODS: Fitness, percentage body fat, BMI, and metabolic syndrome criteria were assessed at baseline in 289 rural women with prehypertension, ages 40-69, enrolled in a healthy eating and activity community-based clinical trial for reducing blood pressure.

RESULTS: Ninety (31%) women had metabolic syndrome, of which 70% were obese by BMI (≥30 kg/m²), 100% by percentage body fat (≥30%), and 100% by revised BMI standards (≥25 kg/m²) cited in current literature. Hierarchical logistic regression models, adjusted for …

Factors That Influence Food Access In The United States: A Snapshot Of Food Access In Ohio And Kentucky, Maimouna Falls

Master of Public Health Program Student Publications

Background: The United States is one the richest countries in the world with a Gross Domestic Product (GDP) per capita of $48,442, yet many communities lack access to affordable nutritious food. Access to food impacts health outcomes such as obesity and diabetes. The purpose of this study was to determine the association between food access and rates of obesity and diabetes in the states of Ohio and Kentucky.

Methods: County level food access data from 120 counties in Kentucky and 88 counties in Ohio were obtained from the USDA website. The dataset included demographic variables and poverty rates. Food access …

The Nature Of Social Support: Self-Efficacy In Overweight And Obese Adolescents, Jenna Bastianello, Matt Epkey, Katy Mcmullin

Mental Health

The purpose of this mixed methods study was to describe the relationship between self-efficacy and social support among overweight and obese adolescents at a weight-management camp. Twenty-three participants completed a pre- and post-camp questionnaire based on modified versions of the GSE Scale and the SSQSR. Additionally, seven females and six males engaged in focus group discussion at the beginning and at the end of camp. Statistical analysis of the modified GSE Scale and SSQSR surveys was completed. Dialogue and field notes from focus group discussions were transcribed and analyzed by the researchers to develop themes. Throughout discussion, participants identified the …

Healthy Lifestyle Programs For Physical Activity And Nutrition, N.A.

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.

A Nhanes 2005-2006 Data Analysis Examining Early Childhood Factors, Food Security, Medical Insurance, And Childhood Obesity, Assanatu Iyatunde Savage

Presidential Alumni Research Dissemination Award

The purpose of this study, and primary research question, was to examine the relationships among early childhood factors, food security, and family medical insurance and childhood obesity. There are many factors associated with the overweight and obesity epidemic. Hence, creating solutions must be addressed on various platforms such as early childhood influences, food security/insecurity, and family availability of health insurance. Relevant and aggregate data on factors affecting childhood obesity could potentially lead to age appropriate interventions to prevent childhood obesity and its sequelae. The literature noted the social cognitive theory in addressing the relationship between parents, the environment, and childhood …

Annual Report To The Nation On The Status Of Cancer, 1975-2008, Featuring Cancers Associated With Excess Weight And Lack Of Sufficient Physical Activity, Christie Eheman, S. Jane Henley, Rachel Ballard-Barbash, Eric J. Jacobs, Maria J. Schymura, Anne-Michelle Noone, Liping Pan, Robert N. Anderson, Janet E. Fulton, Betsy A. Kohler, Ahmedin Jemal, Elizabeth Ward, Marcus Plescia, Lynn A. G. Ries, Brenda K. Edwards

United States Public Health Resources

BACKGROUND: Annual updates on cancer occurrence and trends in the United States are provided through collaboration between the American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR). This year’s report highlights the increased cancer risk associated with excess weight (overweight or obesity) and lack of sufficient physical activity (<150 minutes of physical activity per week).

METHODS: Data on cancer incidence were obtained from the CDC, NCI, and NAACCR; data on cancer deaths were obtained from the CDC’s National Center for Health Statistics. Annual percent changes in …

Mothers' Health And Health Behaviors That Influence Childhod Obesity Maternal Bmi And Infant Feeding Methods, Mohamed Abdullah Alammari

All Graduate Theses, Dissertations, and Other Capstone Projects

The rate of childhood obesity in America continues to climb. Many medical experts believe that childhood obesity can develop as early as prenatal development in the uterus, and infancy. The purpose of this study is to explore the relationships between mothers' health and health behaviors (maternal BMI and infant feeding methods) and childhood obesity. We conducted and analyzed a sample of 307 mothers and their children (307) to examine each mother's maternal BMI and her child or children's BMI. We also examined mothers' feeding methods (bottle vs. breastfeeding).The result of this research did not match with the review of literature. …

Effects Of Adipocyte Deficiency Of Angiotensin Type 1a Receptors In Models Of Obesity And Hypercholesterolemia, Kelly Anne Putnam

Theses and Dissertations--Nutritional Sciences

Adipocytes express angiotensin II (AngII) receptors; however the direct effects of AngII at the adipocyte remain unclear. Knockout mouse models of renin-angiotensin system components exhibit reduced body weight, reduced adiposity, improved glucose tolerance, and improved blood pressure when fed high fat diets, which may be due to reduced action of AngII through the AT1aR in adipocytes. Additionally, hypercholesterolemic AT1aR deficient mice are protected from AngII-induced increases in atherosclerosis and abdominal aortic aneurysm (AAA) formation. We hypothesized that deficiency of AT1aR in adipocytes would reduce the development of obesity, obesity-induced disorders, and vascular diseases. To test this hypothesis, we created a …

Life Course Socio-Economic Measures As Predictors Of Bmi Trajectories And Prevalence Of Diabetes In Adult Life, Tabassum Zarina Insaf

Legacy Theses & Dissertations (2009 - 2024)

Few studies have analyzed the effect of lifecourse socioeconomic position (LSEP) on racial disparities in body mass index (BMI) trajectories and Diabetes. Four waves of the Americans' Changing Lives study (1986-2002) were used to compute BMI trajectories and diabetes prevalence for 3497 Black and White participants. Multivariate associations of LSEP variables (father's education, perceived childhood SEP, education, income, wealth and financial stress) with baseline BMI and BMI change were assessed using mixed models. We also evaluated whether disparate LSEP predictors are influential in Blacks as compared to Whites. Finally we evaluated the presence of latent, pathway and cumulative models of …

The Relationship Between Insulin Resistance And Carotid Artery Intima-Media Thickness In Obese And Morbidly Obese Women, Gülçi̇n Cengi̇z Ecemi̇ş, Hakki Kahraman, Mehmet Seli̇m Nural, Hali̇l Serdar Aslan, Ayşegül Atmaca

Turkish Journal of Medical Sciences

To compare insulin resistance and carotid intima-media thickness (IMT) between obese, morbidly obese, and healthy women and demonstrate whether there is a relation between these parameters, focusing mainly on morbidly obese women. Materials and methods: Twenty-five morbidly obese women (body mass index (BMI) => 40 kg/m^²), 25 obese women (BMI 30-39.9 kg/m^²), and 25 age-matched healthy women (BMI 18.5-24.9 kg/m^²) were recruited for the study. None of the subjects had diabetes mellitus. BMI, waist-to-hip ratio, lipid profiles, fasting glucose and insulin levels, insulin resistance (by HOMA), and IMT (common carotid, internal carotid, and bifurcation measurements) were compared among the 3 …