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Articles 1201 - 1230 of 2493

Full-Text Articles in Medicine and Health Sciences

Effects Of Resistance Training On Muscle Quality Index, Muscle Strength, Functional Capacity, And Serum Immunoglobulin Levels Between Obese And Non-Obese Older Women, Paulo Roberto Silva Junior, Dahan Da Cunha Nascimento, Ivo Vieira De Sousa Neto, Silvana Schwerz Funghetto, Ramires Alsamir Tibana, James W. Navalta, Fabiani Lage Rodrigues Beal, Jonato Prestes Jan 2021

Effects Of Resistance Training On Muscle Quality Index, Muscle Strength, Functional Capacity, And Serum Immunoglobulin Levels Between Obese And Non-Obese Older Women, Paulo Roberto Silva Junior, Dahan Da Cunha Nascimento, Ivo Vieira De Sousa Neto, Silvana Schwerz Funghetto, Ramires Alsamir Tibana, James W. Navalta, Fabiani Lage Rodrigues Beal, Jonato Prestes

Kinesiology and Nutrition Sciences Faculty Research

International Journal of Exercise Science 14(7): 707-726, 2021. Considering the negative impact of obesity on neuromuscular and immune systems, we sought to compare the effects of a 10-week resistance training (RT) program on muscle quality index (MQI), muscle strength, functional capacity, and immunoglobulins in older women with and without obesity. Thirty-nine older women participated in the present study (age: 69.02 ± 6.16, fat (%): 38.80% ± 6.28) and underwent a linear RT program performed on two non-consecutive days of the week. Body composition, functional tests, immunoglobulins, muscle quality of upper and lower limbs and absolute muscular strength of the upper …


Feasibility And Acceptability Of A Technology-Based, Rural Weight Management Int Ervention In Older Adults With Obesity, John A. Batsis, Curtis L. Petersen, Matthew M. Clark, Summer B. Cook, David Kotz, Tyler L. Gooding, Meredith N. Roderka, Rima I. Al-Nimer, Dawna M. Pidgeon, Ann Haedrich, K. C. Wright, Christina Aquila, Todd A. Mackenzie Jan 2021

Feasibility And Acceptability Of A Technology-Based, Rural Weight Management Int Ervention In Older Adults With Obesity, John A. Batsis, Curtis L. Petersen, Matthew M. Clark, Summer B. Cook, David Kotz, Tyler L. Gooding, Meredith N. Roderka, Rima I. Al-Nimer, Dawna M. Pidgeon, Ann Haedrich, K. C. Wright, Christina Aquila, Todd A. Mackenzie

Dartmouth Scholarship

Background

Older adults with obesity residing in rural areas have reduced access to weight management programs. We determined the feasibility, acceptability and preliminary outcomes of an integrated technology-based health promotion intervention in rural-living, older adults using remote monitoring and synchronous video-based technology.

Methods

A 6-month, non-randomized, non-blinded, single-arm study was conducted from October 2018 to May 2020 at a community-based aging center of adults aged ≥65 years with a body mass index (BMI) ≥30 kg/m2. Weekly dietitian visits focusing on behavior therapy and caloric restriction and twice-weekly physical therapist-led group strength, flexibility and balance training classes were delivered using video-conferencing …


Effectiveness Of Behavior-Based Counseling For Weight Loss Maintenance: A Systematic Literature Review, Jaime V. Stanczyk Jan 2021

Effectiveness Of Behavior-Based Counseling For Weight Loss Maintenance: A Systematic Literature Review, Jaime V. Stanczyk

All Graduate Theses, Dissertations, and Other Capstone Projects

Obesity is linked to the development of chronic health conditions such as diabetes, hypertension, and atherosclerotic cardiovascular disease (ASCVD) at an annual expense of $147 billion in related healthcare costs. Effective lifestyle modification treatment for long-term WLM remains elusive. Traditional advice from primary care providers regarding dietary modification and increased physical activity has not led to WLM as a long-term outcome. Newer guidelines for the treatment of obesity now recommend high-intensity behavior-based counseling (BBC) programs that deliver traditional weight loss education in tandem with behavior-change strategies. Methods: A database search was conducted for peer reviewed literature published in 2012-2020 on …


Experience Of The Obese Population With Weight Bias/Stigma, Gary Mathew Brown Jan 2021

Experience Of The Obese Population With Weight Bias/Stigma, Gary Mathew Brown

Walden Dissertations and Doctoral Studies

Obesity management has been identified as an important issue in health promotion, and some researchers have also reported that people who are obese often do not seek health care. Yet, current research is lacking on the complexities of weight stigma from the perspective of people who are obese. The purpose of this qualitive descriptive study was to understand the perceptions of weight bias/stigma of obese individuals. Guided by Goffman’s Theory of Social Stigma and the Health Belief Model, purposive sampling was used to recruit 10 participants who had a body mass index greater than 30 and who lived in West …


The Impact Of Self-Esteem And Body Dissatisfaction On Internalized Stigma In Obese, Hispanic Women, Dorothy M. Burns Jan 2021

The Impact Of Self-Esteem And Body Dissatisfaction On Internalized Stigma In Obese, Hispanic Women, Dorothy M. Burns

Walden Dissertations and Doctoral Studies

AbstractThe current literature on self-esteem (SE), body dissatisfaction (BD) and internalized weight stigma (IWS) was limited, albeit evolving. The variables were well established across multiple domains of study: IWS was consistently noted to be a contributing factor for the development of obesity, but no studies explored the relationship between SE and BD on IWS. Therefore, the purpose of this correlational study was to explore the relationship between SE and BD and their effect on IWS in 30–44-year-old, obese, Hispanic women who are 20% more likely to be overweight or obese than non-Hispanic women. The study was guided by symbolic interactionism …


Internet Use, Perceived Social Support, And Obesity Among African American Young Adults, Cynthia Adams Jan 2021

Internet Use, Perceived Social Support, And Obesity Among African American Young Adults, Cynthia Adams

Walden Dissertations and Doctoral Studies

African Americans are disproportionately affected by obesity. Public health practitioners have an incomplete understanding of the social-environmental risk factors and how they affect obesity. The purpose of this quantitative, cross-sectional study was to explore whether internet use and perceived social support predicted obesity among African American young adults. The social cognitive theory guided this study. Secondary data were analyzed from the 2017 Behavioral Risk Factor Surveillance Survey. The sample consisted of 6,765 African American young adults age 18 to 34 and represented the U.S. population using weighted estimates. A Bonferroni correction was performed to reduce Type I error due to …


Association Between Bisphenols, Acrylamide, Glycidamide, Fast Food, And Obesity: An Obesogenic Perspective, Morgan Murphy Jan 2021

Association Between Bisphenols, Acrylamide, Glycidamide, Fast Food, And Obesity: An Obesogenic Perspective, Morgan Murphy

Walden Dissertations and Doctoral Studies

Endocrine disrupting chemicals (EDCs) are exogenous man-made substances that have the ability to interfere with hormone action and are believed to be a contributing factor to chronic illnesses, including but not limited to obesity. Recent studies have suggested that environmental agents (environmental obesogens), such as food additives, plasticizers, and personal care products are contributors that aid in the altering of hormone receptors and hormone mimicry. Such environmental obesogens have the potential to promote adipogenesis and fat accumulation. In this study, the social-ecological model was used to determine the factors that can influence the increased exposure to obesogenic chemicals at the …


Analyzing Regional Impact Of Caregiving On Obesity Prevalence Among U.S. Adults, Myra Callis Johnston Jan 2021

Analyzing Regional Impact Of Caregiving On Obesity Prevalence Among U.S. Adults, Myra Callis Johnston

Walden Dissertations and Doctoral Studies

Obesity remains one of the leading causes of morbidity and mortality in the United States. Historically, sparse research efforts have focused on informal caregiving as a possible risk factor for developing chronic illnesses across the United States. Identifying additional subgroups at higher risk of becoming obese could provide insights into where public health practitioners, the health care community, and policy makers can direct limited resources through a more targeted approach. The theoretical foundation for the current project was the social cognitive theory. In this secondary correlational analysis using the 2018 Behavioral Risk Factor Surveillance System data set, the relationship between …


Examination Of The Efficacy Of The Healthy Hunger-Free Kids Act To Reduce High School Childhood Obesity Rates System, Catrina Lashawn Morgan Jan 2021

Examination Of The Efficacy Of The Healthy Hunger-Free Kids Act To Reduce High School Childhood Obesity Rates System, Catrina Lashawn Morgan

Walden Dissertations and Doctoral Studies

The rapid rise in U.S. high school student obesity rates to 20.8% in 2018 presented significant risks to the health and well-being of American children and foreshadowed increased future healthcare costs. To address high school obesity, Congress passed the Healthy Hunger-Free Kids Act (HHFKA) in 2010 that mandated the U.S. Department of Agriculture develop regulations to nutrition to improve the nutrition of school cafeteria breakfasts and lunches. The purpose of this quantitative study was to test for changes between 2009 and 2016 in high school obesity rates attributable to the HHFKA using Youth Risk Behavior Surveillance System data, adjusted for …


Predictors Of Obesity Among Young Adults In The State Of Maryland, Kala Shahi Jan 2021

Predictors Of Obesity Among Young Adults In The State Of Maryland, Kala Shahi

Walden Dissertations and Doctoral Studies

AbstractObesity has become a global wellness concern for young adults. In the past, there were very few studies conducted on predictors of obesity among young adults, even though there have been several studies on the potential predictors of obesity on the general population. The social ecological model was used to guide this quantitative cross-sectional study to identify the possible predictors of obesity among young adults. The Behavioral Risk Factor Surveillance System was used to analyze the potential predictors of obesity among young adults between the ages 18 – 34 years old in Montgomery County, Frederick County, and Princess Georges County, …


Exploring Ethnic And New Orleans Cultural Influences On Health Behaviors Of African American Women, Keneitra Brown-Mayfield Jan 2021

Exploring Ethnic And New Orleans Cultural Influences On Health Behaviors Of African American Women, Keneitra Brown-Mayfield

Walden Dissertations and Doctoral Studies

In the United States (U.S.), African American women suffer disproportionately due to obesity and chronic diseases. Many studies have examined the culture of African Americans and its influence on their health behaviors in order to gain knowledge to inform obesity and chronic disease prevention interventions. However, a geographical segment of the U.S. African American population shares a unique culture that had yet to be studied. This qualitative study used in-depth interviews to understand the perceptions of overweight and obese African American women living in the Greater New Orleans region about their culture’s role in the prevalence of obesity and obesity-related …


Subclinical Stress On Obesity Among Obese African American Women, Dr. Nosakhare Osasu Idehen Jan 2021

Subclinical Stress On Obesity Among Obese African American Women, Dr. Nosakhare Osasu Idehen

Walden Dissertations and Doctoral Studies

AbstractObesity is a complex disease linked to genetics, health behaviors, upstream social determinants of health, and psychosocial stress. Obesity-related chronic diseases and opportunity cost significantly impact individuals and communities. Current prevention policies focus on diet and exercise without demonstrating the benefits of stress coping strategies in obesity management. Subclinical racial minority and gender stress heighten hypervigilance, psychological overload, poor stress coping strategies, inflammation, and obesity. Subclinical stress varies with race and gender, and it is higher in African American (AA) women. The purpose of this qualitative study was to explore the lived experience of subclinical racial minority and gender stress …


The Role Of Obesity, Gdm, And Lifestyle Factors On Metabolic Syndrome Scores In Mothers And Their Children 4-10 Years After Pregnancy, Makenzie Callahan Jan 2021

The Role Of Obesity, Gdm, And Lifestyle Factors On Metabolic Syndrome Scores In Mothers And Their Children 4-10 Years After Pregnancy, Makenzie Callahan

All ETDs from UAB

Metabolic syndrome (MetS) is a cluster of symptoms that increase risk for heart disease and type 2 diabetes. Therefore, early detection of MetS is vital for disease prevention. Gestational diabetes (GDM) and/or obesity during pregnancy are associated with a greater risk for MetS in mothers and their children compared to mothers with no GDM. However, little is known about how much a GDM history or in utero exposure to maternal GDM contributes to MetS risk years after that pregnancy in addition to risk attributable to obesity itself. Therefore, the overall objective of this dissertation was explore how a history of …


Do Outcomes From A Behavioral Weight Loss Intervention Differ In Alabama Vs Colorado?, Julianne Clina Jan 2021

Do Outcomes From A Behavioral Weight Loss Intervention Differ In Alabama Vs Colorado?, Julianne Clina

All ETDs from UAB

There are well-established regional differences in obesity prevalence in the U.S., but relatively little is known about whether these differences impact efforts for weight loss. The objective of the study was to determine whether changes in body weight, engagement in physical activity (PA), and psychosocial factors differed in Colorado (CO) vs Alabama (AL) in response to a 16 week standardized behavioral weight management program. We hypothesized that weight loss would be greater in Colorado due to a more favorable physical and social environment.This is an ancillary study to a weight loss intervention being conducted simultaneously in AL and CO with …


F-Wave Parameters And Body Mass Index In Carpal Tunnel Syndrome, Philip Adebayo, Rose E. Mwakabatika Jan 2021

F-Wave Parameters And Body Mass Index In Carpal Tunnel Syndrome, Philip Adebayo, Rose E. Mwakabatika

Internal Medicine, East Africa

Background: Severe carpal tunnel syndrome (CTS) readily lends itself to both clinical and electrophysiological recognition. The uncertainty sometimes is in identifying and quantifying motor involvement in mild and, perhaps, in moderate CTS. Our study aimed to evaluate F responses in mild and moderate CTS and determine the contribution of BMI to the F-wave parameters.

Methods: A retrospective review of the clinical and electrophysiological data of patients with CTS seen at the clinical neurophysiology laboratory of Aga Khan Hospital, Dar es Salaam, between 1 August 2017 and 31 July 2019 was retrieved. Carpal tunnel syndrome was graded according to the …


Disordered Eating, Food Insecurity, And Weight Status Among Transgender And Gender Nonbinary Youth And Young Adults: A Cross-Sectional Study Using A Nutrition Screening Protocol, Whitney R. Linsenmeyer, Ian M. Katz, Jaime L. Reed, Andrea M. Giedinghagen, Christopher B. Lewis, Sarah K. Garwood Jan 2021

Disordered Eating, Food Insecurity, And Weight Status Among Transgender And Gender Nonbinary Youth And Young Adults: A Cross-Sectional Study Using A Nutrition Screening Protocol, Whitney R. Linsenmeyer, Ian M. Katz, Jaime L. Reed, Andrea M. Giedinghagen, Christopher B. Lewis, Sarah K. Garwood

Psychology Faculty Publications

Purpose: The purpose of this study was to describe the prevalence of and relationships among disordered eating, food insecurity, and weight status among transgender and gender nonbinary youth and young adults.

Methods: This cross-sectional study involved a screening protocol to assess disordered eating and food insecurity risk from September to December of 2019 at a gender clinic using five validated measures: (1) previous eating disorder diagnosis (yes/no); (2) Sick, Control, One Stone, Fat, Food Questionnaire (SCOFF); (3) Adolescent Binge Eating Disorder Questionnaire (ADO-BED); (4) Nine-Item Avoidant/Restrictive Food Intake Disorder Screen (NIAS); and (5) Hunger Vital Sign. Age, assigned sex at …


Examining The Ecological Validity Of The Power Of Food Scale, Lindsay M. Howard, Kristin E. Heron, Kathryn E. Smith, Ross D. Crosby, Scott G. Engel, Stephen A. Wonderlich, Tyler B. Mason Jan 2021

Examining The Ecological Validity Of The Power Of Food Scale, Lindsay M. Howard, Kristin E. Heron, Kathryn E. Smith, Ross D. Crosby, Scott G. Engel, Stephen A. Wonderlich, Tyler B. Mason

Psychology Faculty Publications

Purpose

Appetite for palatable foods may impact eating-related behaviors in everyday life. The present study evaluated the real-world predictive validity of the Power of Food Scale (PFS) using ecological momentary assessment (EMA).

Methods

30 women who reported binge eating completed the PFS and related measures. Subsequently, during a 14-day assessment period, participants completed five daily EMA surveys of appetite and binge eating via text message and web.

Results

Results of generalized estimating equations showed that higher PFS scores were associated with higher momentary levels of hunger, eagerness to eat, and urge to eat but were unrelated to fullness, preoccupation with …


Opportunities, Barriers, And Recommendations In Down Syndrome Research., James A. Hendrix, Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson, Lisa J. Bain, Nicole Baumer, Anita Bhattacharyya, Dusan Bogunovic, Kelly N. Botteron, George Capone, Priya Chandan, Isabelle Chase, Brian Chicoine, Cécile Cieuta-Walti, Lara R. Deruisseau, Sophie Durand, Anna Esbensen, Juan Fortea, Sandra Giménez, Ann-Charlotte Granholm, Laura J. Hahn, Elizabeth Head, Hampus Hillerstrom, Lisa M. Jacola, Matthew P. Janicki, Joan M. Jasien, Angela R. Kamer, Raymond D. Kent, Bernard Khor, Jeanne B. Lawrence, Catherine Lemonnier, Amy Feldman Lewanda, William Mobley, Paul E. Moore, Linda Pollak Nelson, Nicolas M. Oreskovic, Ricardo S. Osorio, David Patterson, Sonja A. Rasmussen, Roger H. Reeves, Nancy Roizen, Stephanie Santoro, Stephanie L. Sherman, Nasreen Talib, Ignacio E. Tapia, Kyle M. Walsh, Steven F. Warren, A Nicole White, Guang William Wong, John S. Yi Jan 2021

Opportunities, Barriers, And Recommendations In Down Syndrome Research., James A. Hendrix, Angelika Amon, Leonard Abbeduto, Stamatis Agiovlasitis, Tarek Alsaied, Heather A. Anderson, Lisa J. Bain, Nicole Baumer, Anita Bhattacharyya, Dusan Bogunovic, Kelly N. Botteron, George Capone, Priya Chandan, Isabelle Chase, Brian Chicoine, Cécile Cieuta-Walti, Lara R. Deruisseau, Sophie Durand, Anna Esbensen, Juan Fortea, Sandra Giménez, Ann-Charlotte Granholm, Laura J. Hahn, Elizabeth Head, Hampus Hillerstrom, Lisa M. Jacola, Matthew P. Janicki, Joan M. Jasien, Angela R. Kamer, Raymond D. Kent, Bernard Khor, Jeanne B. Lawrence, Catherine Lemonnier, Amy Feldman Lewanda, William Mobley, Paul E. Moore, Linda Pollak Nelson, Nicolas M. Oreskovic, Ricardo S. Osorio, David Patterson, Sonja A. Rasmussen, Roger H. Reeves, Nancy Roizen, Stephanie Santoro, Stephanie L. Sherman, Nasreen Talib, Ignacio E. Tapia, Kyle M. Walsh, Steven F. Warren, A Nicole White, Guang William Wong, John S. Yi

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Recent advances in medical care have increased life expectancy and improved the quality of life for people with Down syndrome (DS). These advances are the result of both pre-clinical and clinical research but much about DS is still poorly understood. In 2020, the NIH announced their plan to update their DS research plan and requested input from the scientific and advocacy community.

OBJECTIVE: The National Down Syndrome Society (NDSS) and the LuMind IDSC Foundation worked together with scientific and medical experts to develop recommendations for the NIH research plan.

METHODS: NDSS and LuMind IDSC assembled over 50 experts across …


Does Accurate Data, Identifying Obese Patients Impact Nurse Safety And Hospital Finances?, Kim Mcclean Jan 2021

Does Accurate Data, Identifying Obese Patients Impact Nurse Safety And Hospital Finances?, Kim Mcclean

Theses: Doctorates and Masters

Healthcare staff who manage obese patients are at increased risk of sustaining patient handling injuries, and this risk is anticipated to intensify as projected Australian obesity rates increase to 42% by the year 2035 and obese patients admitted to hospitals also increase. High cost burdens to healthcare organisations will result due to increased funding requirements for bariatric risk management solutions and growing costs of workers’ compensation claims of injured staff. Five (5) studies explored if identification of obese patients impacts the safety of nurses and other healthcare staff who manage obese patients and investigated the accuracy of obesity data recorded …


Prevalence And Factors Associated With Nafld Detected By Vibration Controlled Transient Elastography Among Us Adults: Results From Nhanes 2017–2018, Xiaotao Zhang, Natalia I Heredia, Maya Balakrishnan, Aaron P Thrift Jan 2021

Prevalence And Factors Associated With Nafld Detected By Vibration Controlled Transient Elastography Among Us Adults: Results From Nhanes 2017–2018, Xiaotao Zhang, Natalia I Heredia, Maya Balakrishnan, Aaron P Thrift

Faculty, Staff and Students Publications

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is increasingly common in the adult population. In the United States, the overall burden of NAFLD is unknown due to challenges with population-level NAFLD detection. The purpose of this study was to estimate prevalence of NAFLD and significant NAFLD fibrosis and identify factors associated with them in the U.S.

METHODS: Data came from the 2017-2018 cycle of National Health and Nutrition Examination Survey. We defined NAFLD by controlled attenuation parameter (CAP) scores of ≥248 dB/m in absence of excessive alcohol use and viral hepatitis. We defined significant fibrosis as Vibration controlled transient elastography (VCTE) …


The Role Of Sleep Curtailment On Leptin Levels In Obesity And Diabetes Mellitus, Maryam Mosavat, Mitra Mirsanjari, Diana Arabiat, Aisling Smyth, Lisa Whitehead Jan 2021

The Role Of Sleep Curtailment On Leptin Levels In Obesity And Diabetes Mellitus, Maryam Mosavat, Mitra Mirsanjari, Diana Arabiat, Aisling Smyth, Lisa Whitehead

Research outputs 2014 to 2021

Emerging evidence has identified sleep as a significant, but modifiable, risk factor for metabolic syndrome, diabetes, and obesity. Leptin, an adipocyte-derived peptide and a regulator of food intake and energy expenditure, has been shown to be associated with a short sleep duration in the pathophysiology of obesity and consequently type 2 diabetes. This review focuses on the current evidence indicating the effects of a short sleep duration on the regulation of leptin concentration in association with obesity and diabetes mellitus. In summary, the evidence suggests that sleep deprivation, by affecting leptin regulation, may lead to obesity and consequently development of …


Estimated Financial Impacts Of Inaccurate Obese Patient Data Recorded By The Western Australian Country Health Service, Kim Mcclean, Martyn Cross, Sue Reed Jan 2021

Estimated Financial Impacts Of Inaccurate Obese Patient Data Recorded By The Western Australian Country Health Service, Kim Mcclean, Martyn Cross, Sue Reed

Research outputs 2014 to 2021

Purpose: Pressure on Australia’s healthcare system is increasing annually due to corresponding increases in chronic diseases such as obesity and rapidly ageing population growth across Australia, resulting in requirements for increased funding. This study investigates the financial impact to hospitals due to inaccurate obese patient recording and coding.

Background: Australian healthcare organisations receive Activity-Based Funding (ABF) which provides reimbursement of costs relating to the type of patient care delivered and the resources required for the patient treatment. Accurate healthcare data are essential to ensure accuracy of ABF and appropriate reimbursement of costs incurred by hospitals that manage obese patients. Managing …


The Bile Acid Induced Hepatokine Orosomucoid Suppresses Adipocyte Differentiation, Sung Ho Lee, Jong Min Choi, Sung Yun Jung, Aaron R Cox, Sean M Hartig, David D Moore, Kang Ho Kim Jan 2021

The Bile Acid Induced Hepatokine Orosomucoid Suppresses Adipocyte Differentiation, Sung Ho Lee, Jong Min Choi, Sung Yun Jung, Aaron R Cox, Sean M Hartig, David D Moore, Kang Ho Kim

Faculty, Staff and Students Publications

Bile acids have recently emerged as key metabolic hormones with beneficial impacts in multiple metabolic diseases. We previously discovered that hepatic bile acid overload distally modulates glucose and fatty acid metabolism in adipose tissues to exert anti-obesity effects. However, the detailed mechanisms that explain the salutary effects of serum bile acid elevation remain unclear. Here, proteomic profiling identified a new hepatokine, Orosomucoid (ORM) that governs liver-adipose tissue crosstalk. Hepatic ORMs were highly induced by both genetic and dietary bile acid overload. To address the direct metabolic effects of ORM, purified ORM proteins were administered during adipogenic differentiation of 3T3-L1 cells …


Adipocyte-Specific Ablation Of Pu1 Promotes Energy Expenditure And Ameliorates Metabolic Syndrome In Aging Mice, Ke Yun Chen, Alejandra De Angulo, Xin Guo, Aditya More, Scott A Ochsner, Eduardo Lopez, David Saul, Weijun Pang, Yuxiang Sun, Neil J Mckenna, Qiang Tong Jan 2021

Adipocyte-Specific Ablation Of Pu1 Promotes Energy Expenditure And Ameliorates Metabolic Syndrome In Aging Mice, Ke Yun Chen, Alejandra De Angulo, Xin Guo, Aditya More, Scott A Ochsner, Eduardo Lopez, David Saul, Weijun Pang, Yuxiang Sun, Neil J Mckenna, Qiang Tong

Faculty, Staff and Students Publications

Objective: Although PU.1/Spi1 is known as a master regulator for macrophage development and function, we have reported previously that it is also expressed in adipocytes and is transcriptionally induced in obesity. Here, we investigated the role of adipocyte PU.1 in the development of the age-associated metabolic syndrome.

Methods: We generated mice with adipocyte-specific PU.1 knockout, assessed metabolic changes in young and older adult PU.1fl/fl (control) and AdipoqCre PU.1fl/fl (aPU.1KO) mice, including body weight, body composition, energy expenditure, and glucose homeostasis. We also performed transcriptional analyses using RNA-Sequencing of adipocytes from these mice.

Results: aPU.1KO mice have elevated energy …


Exercise Attenuates Bone Mineral Density Loss During Diet-Induced Weight Loss In Adults With Overweight And Obesity: A Systematic Review And Meta-Analysis, Jakub Mesinovic, Paul Jansons, Ayse Zengin, Barbora De Courten, Alexander J. Rodriguez, Robin M. Daly, Peter R. Ebeling, David Scott Jan 2021

Exercise Attenuates Bone Mineral Density Loss During Diet-Induced Weight Loss In Adults With Overweight And Obesity: A Systematic Review And Meta-Analysis, Jakub Mesinovic, Paul Jansons, Ayse Zengin, Barbora De Courten, Alexander J. Rodriguez, Robin M. Daly, Peter R. Ebeling, David Scott

Research outputs 2014 to 2021

Background: Weight-loss-induced fat loss improves cardiometabolic health in individuals with overweight and obesity; however, weight loss can also result in bone loss and increased fracture risk. Weight-loss-induced bone loss may be attenuated with exercise. Our aim was to compare changes in bone mineral density (BMD) in adults with overweight and obesity who undertook diet-induced weight loss alone or in combination with exercise. Methods: We included randomized controlled trials (RCTs) in adults with overweight or obesity (aged ≥ 18 years; body mass index ≥ 25 kg/m2) that prescribed diet-induced weight loss alone or in combination with supervised exercise, and measured any …


The Effectiveness Of Nurse-Led Interventions To Prevent Childhood And Adolescent Overweight And Obesity: A Systematic Review Of Randomised Trials, Lisa Whitehead, Istvan (Ishti) Kabdebo, Melissa Dunham, Robyn Quinn, Jennifer Hummelshoj, Cobie George, Elizabeth Denney-Wilson Jan 2021

The Effectiveness Of Nurse-Led Interventions To Prevent Childhood And Adolescent Overweight And Obesity: A Systematic Review Of Randomised Trials, Lisa Whitehead, Istvan (Ishti) Kabdebo, Melissa Dunham, Robyn Quinn, Jennifer Hummelshoj, Cobie George, Elizabeth Denney-Wilson

Research outputs 2014 to 2021

Background:

Obesity among children and adolescents continues to rise worldwide. Despite the efforts of the healthcare workforce, limited high-quality evidence has been put forward demonstrating effective childhood obesity interventions. The role of nurses as primary actors in childhood obesity prevention has also been underresearched given the size of the workforce and their growing involvement in chronic disease prevention.

Aim:

To examine the effectiveness of nurse-led interventions to prevent childhood and adolescent overweight and obesity.

Design:

A systematic review of randomised trials.

Data sources:

Medline, CINAHL, EMBASE, Cochrane (CENTRAL), ProQuest Central and SCOPUS were searched from inception to March 2020.

Review …


Identifikasi Penyebab Kenaikan Berat Badan Pada Anak Usia Dini, Rahmat Sanusi, Widiyanto Widiyanto, Ronny Brayntin Rahail Dec 2020

Identifikasi Penyebab Kenaikan Berat Badan Pada Anak Usia Dini, Rahmat Sanusi, Widiyanto Widiyanto, Ronny Brayntin Rahail

Jurnal Keolahragaan

Upaya pencegahan masalah berat badan berlebih menjadi fokus utama saat ini berdasarkan peningkatan resiko kesehatan akibat overweight dan obesitas, teruatama pada anak-anak. Penelitian ini bertujuan untuk mengindentifikasi penyebab kenaikan berat badan pada anak usia dini dengan metode penelitian cross sectional. Jumlah subjek penelitian terdiri dari enam puluh enam anak. Teknik analisa yang digunakan adalah analisis multivariat. Hasil penelitian menujukkan terdapat hubungan bermakna (p < 0.05) antara variabel varian terhadap kenaikan berat pada anak usia dini. Hasil penelitian disimpulkan bahwa faktor rendahnya aktivitas fisik, genetik dari orang tua dan pola makan berhubungan terhadap kenaikan berat badan pada anak usia dini.

Identify the causes of weight gain in early childhood

Abstract

Today, the efforts to prevent weight gain excess become the main focus base on increased health risk consequences of overweight and obesity, especially in childhood. This …


Determinan Sosial Ekonomi Terhadap Berat Badan Lebih Dan Obesitas Di Indonesia: Analisis Data Ifls 2014, Fajar Nugraha, Riki Relaksana, Adiatma Y. M. Siregar Dec 2020

Determinan Sosial Ekonomi Terhadap Berat Badan Lebih Dan Obesitas Di Indonesia: Analisis Data Ifls 2014, Fajar Nugraha, Riki Relaksana, Adiatma Y. M. Siregar

Jurnal Ekonomi Kesehatan Indonesia

The phenomenon of overweight and obesity has become a serious problem in various countries, especially in Indonesia. According to WHO in 2016 there were 2.8 million people who died due to the problem of overweight and obesity, while according to the Indonesian Ministry of Health the prevalence of overweight and obesity in Indonesia in 2018 reached 13,6% and 21.8%. One of the factors that cause overweight and obesity is socio-economic status. However, there are often differences regarding the effect of socioeconomic status on obesity in developing and developed countries. This study aims to identify the determinant factors of socioeconomic status …


“We’Re, Like, The Most Unhealthy People In The Country”: Employing An Equity Lens To Reduce Barriers To Healthy Food Access In Rural Appalachia, Kathryn Cardarelli, Emily M. Dewitt, Rachel Gillespie, Heather Norman-Burgdolf, Natalie Jones, Janet Tietyen Mullins Dec 2020

“We’Re, Like, The Most Unhealthy People In The Country”: Employing An Equity Lens To Reduce Barriers To Healthy Food Access In Rural Appalachia, Kathryn Cardarelli, Emily M. Dewitt, Rachel Gillespie, Heather Norman-Burgdolf, Natalie Jones, Janet Tietyen Mullins

Dietetics and Human Nutrition Faculty Publications

Introduction

Obesity disproportionately affects rural communities, and Appalachia has some of the highest obesity rates in the nation. Successful policy, systems, and environmental (PSE) interventions to reduce obesity must reflect the circumstances of the population. We used a health equity lens to identify barriers and facilitators for healthy food access in Martin County, Kentucky, to design interventions responsive to social, cultural, and historical contexts.

Methods

We conducted 5 focus groups in Martin County, Kentucky, in fall 2019 to obtain perspectives on the local food system and gauge acceptability of PSE interventions. We used grounded theory to identify perceived barriers and …


Association Between Dietary Macronutrient Intake And High-Sensitivity C-Reactive Protein Levels Among Obese Women In Kuantan, Malaysia, Siti Zuhaidah Shahadan, Azlina Daud, Muhammad Ibrahim, Muhammad Lokman Md. Isa, Samsul Draman Dec 2020

Association Between Dietary Macronutrient Intake And High-Sensitivity C-Reactive Protein Levels Among Obese Women In Kuantan, Malaysia, Siti Zuhaidah Shahadan, Azlina Daud, Muhammad Ibrahim, Muhammad Lokman Md. Isa, Samsul Draman

Makara Journal of Science

Elevated high-sensitivity C-reactive protein (hs-CRP) levels may be associated with an increased risk of cardiovascular disease (CVD). In general, an individual’s dietary intake may influence the hs-CRP level. However, evidence on the influence of dietary macronutrient intake on hs-CRP levels among obese Malaysian women remains fragmented. Therefore, this study aims to investigate the association between the hs-CRP level and dietary macronutrient intake of obese adults living in Kuantan. The assessment of 24-hour dietary recall and venous hs-CRP levels were investigated in 67 women with a body mass index of 27.5 to 39.9 kg/m². The findings revealed that obese women living …