Medicine and Health Sciences Commons^™

Pet/Ct Variants And Pitfalls In Malignant Melanoma, Nicolas Aide, Amir Iravani, Kevin Prigent, Diane Kottler, Ramin Alipour, Rodney J Hicks

2020-Current year OA Pubs

No abstract provided.

Pivoting To Be Patient-Centered: A Study On Hidden Psychological Costs Of Tele-Healthcare And The Patient-Provider Relationship, Adam Neufeld, Vishal Bhella, Clark Svrcek

Internet Journal of Allied Health Sciences and Practice

Purpose: While the COVID-19 pandemic has necessitated a shift toward virtual medicine, there are some potentially important limitations with this modality of healthcare. One such concern, which has not yet been elucidated, is how telephone-based versus in-person visits differentially impact patients’ perceived autonomy and the resulting patient-provider relationship. Grounded in self-determination theory (SDT), this pilot study addresses this question by investigating the association between patients’ perceived autonomy support and relationship needs satisfaction (autonomy, competence, relatedness) in both types of visits with their family doctor and care team. Methods: Running from Sept. 2020 to Feb. 2021, data was collected via convenience …

Attitudes And Usage Of Face Masks During The Covid-19 Pandemic Among Occupational Therapy Professionals In Texas, Stephen A. Cage, Diane P. Brown, Brandon J. Warner, Diana M. Gallegos, Heidi M. Cage

Internet Journal of Allied Health Sciences and Practice

Purpose: Following the widespread transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), multiple business and schools drastically reduced face-to-face services. Additionally, many state and local governments enacted face mask mandates and other legislations aimed at decreasing the spread of the virus. Current research is being conducted to evaluate the epidemiology, recognition, treatment, and prevention of coronavirus disease 2019 (COVID-19), the disease associated with SARS-CoV-2. At the time of this study, there is no published research on the attitudes and usage of face masks or face coverings among certified occupational therapy professionals during the COVID-19 Pandemic. The purpose of this …

Examining Factors Associated With The Use Of Face Coverings During Covid-19: A Survey Of Shoppers In Greater Grand Forks, Minnesota And North Dakota, Isaac Karikari, Tanis J. Walch, Ashley Evenson, Carenlee Bardull, Bret Weber, Stephanie Scallon, Delton Gabe, Mikale Kuntz, Gabriel Wavra, Emily Possis, Courtney Leben, Hailer Boushee, Madeline Comeau

Social Work Faculty Publications

Despite the availability of COVID-19 vaccines, the pandemic’s persistence and recent spikes in cases have heightened the need for the promotion of protective behaviors notably, the continued use of face coverings (or ‘masks’ in the common parlance for COVID-related face coverings). Effective messaging on mask use is essential to more fully resonate with individuals and their shared communities. Studies covering rural or mostly-urban regions in the U.S. are sparse. Accordingly, an interdisciplinary team of social work and public health researchers explored mask wearing behaviors in a small, urban metro community consisting of two cities spanning North Dakota and Minnesota that …

2022-01-03 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2022-01-03_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …

Factors Predicting Intention To Initiate Mental Health Services Among College Students Returning To Campus During Covid-19, Anne Dumadag, Cara Tonn, Hadiza Galadima

College of Health Sciences Posters

Introduction: While the impact of transitioning to a virtual learning environment during the COVID-19 pandemic is well-documented, few studies have explored the mental health impact of reopening campus. As a measurement of mental health impact within the context of reopening campus, this study aims to identify factors associated with intention to initiate mental health services (MHS), with a particular focus on race, among college students.

Methods: A cross-sectional survey using stratified sampling was conducted via Qualtrics among students at a Virginia university in January 2022. The survey assessed demographics, online class experiences, past and future use of MHS, and feelings …

At War With A Silent Killer: An Ipa Study Of The Lived Experiences Of Community Pharmacists In Ireland During Covid-19, Regina Brady, Niamh Imbusch

Articles

Objectives: The purpose of this research was to give voice to the unique lived experiences of community pharmacists who continued to work in patient-facing roles throughout the COVID-19 pandemic. Research objectives sought to understand how they felt about working during this time including any risks felt, why they choose to continue working, and what the post-COVID future might hold for them and their profession. Method: The study was guided by the principles of traditional interpretative phenomenological analysis (IPA). Primary research was collated using semi-structured interviews of a small, purposively selected homogenous group of pharmacists. The research context was a …

Covid-19 Financial Consequences In United States Hospitals, Hannah T. Osburn, Murat Mert Solakoglu, Gretel Toloza Alvarez

Theses, Dissertations and Capstones

Introduction: Since the wake of the coronavirus pandemic, United States (U.S.) hospitals have struggled to stay financially afloat amid the constant battle with unprecedented circumstances and financial consequences from the pandemic. The purpose of this research was to analyze the financial consequences of COVID-19 for U.S. hospitals to determine the impact on the number of inpatient cases, length of stay (LOS), surgeries performed, and operating expenses. The hypothesis was that U.S. hospitals were financially affected by the consequences of COVID-19, having more inpatient cases, increased LOS, fewer surgeries performed, and higher operating expenses.

Methodology: The methodology for this …

Creating A Pre-Illness Covid-19 Action Plan: A Web-Based Public Education Initiative, Brian S. Hustad

DNP Research Projects

Abstract

Background: The COVID-19 pandemic took the world by storm in the beginning stages of 2020. Public health agencies were overwhelmed, undermanned, and therefore slow to respond. Information began to flow at an unprecedented rate. Yet, very limited resources were put into place to present this information or to instruct the public on evidence-based prevention, treatment, or care at home during active infection.

Intervention: A project website was created and accessed through a QR code on the project flyer or by entering the URL into any browser. Participants were able to access three evidence- based video modules, which introduced the …

Lineage Abundance Estimation For Sars-Cov-2 In Wastewater Using Transcriptome Quantification Techniques, Jasmijn A. Baaijens, Alessandro Zulli, Isabel M. Ott, Ioanna Nika, Mart J. Van Der Lugt, Mary E. Petrone, Tara Alpert, Joseph R. Fauver, Chaney C. Kalinich, Chantal B. F. Vogels, Mallery I. Breban, Claire Duvallet, Kyle A. Mcelroy, Newsha Ghaeli, Maxim Imakaev, Malaika F. Mckenzie-Bennett, Keith Robison, Alex Plocik, Rebecca Schilling, Martha Pierson, Rebecca Littlefield, Michelle L. Spencer, Birgitte B. Simen, Yale Sars-Cov-2 Genomic Surveillance Initiative, William P. Hanage, Nathan D. Grubaugh, Jordan Peccia, Michael Baym

Journal Articles: Epidemiology

Effectively monitoring the spread of SARS-CoV-2 mutants is essential to efforts to counter the ongoing pandemic. Predicting lineage abundance from wastewater, however, is technically challenging. We show that by sequencing SARS-CoV-2 RNA in wastewater and applying algorithms initially used for transcriptome quantification, we can estimate lineage abundance in wastewater samples. We find high variability in signal among individual samples, but the overall trends match those observed from sequencing clinical samples. Thus, while clinical sequencing remains a more sensitive technique for population surveillance, wastewater sequencing can be used to monitor trends in mutant prevalence in situations where clinical sequencing is unavailable.

The Effects Of The Covid-19 Pandemic On Postgraduate Endodontic Programs In The United States, Bianca Aboubakare, James Chen, Johnah C. Galicia

Orthodontics and Endodontics Theses

In December 2019, the coronavirus disease 2019 (COVID-19) was first identified as an acute infectious disease in Wuhan, China and subsequently led to an ongoing pandemic. At the onset of the pandemic, dental professionals were understood to face the greatest exposure risk to SARS-Cov-2 due to aerosolization of fluids from the oral cavity and respiratory airways . As a result, dental professionals, including academic institutions and their students and residents halted much of their operations to minimize exposure risks and potentially slow the spread of infection to peers and patients alike. Currently, there is little in the literature that describes …

Violence Against Healthcare Workers: An Epidemic Within A Pandemic, Michaela Ramandanes

College of Health Sciences Posters

Violence and harassment towards healthcare workers has been an underlying problem throughout history. However, with the rapid and evolving onset of the COVID-19 pandemic, the risks that healthcare workers face has been a focal topic of discussion among administration, staff and the public. What was once considered an occupational hazard is now being raised as a public health issue- an epidemic within a pandemic. This literature review seeks to identify the prevalence and causes of violence and harassment towards healthcare workers. Was healthcare violence as prevalent before COVID-19? Has violence increased because patient volume increased? Additionally, this review will determine …

Cholinergic Anti-Inflammatory Pathway And Covid-19, Danial Mehranfard, Robert C. Speth

HPD Articles

The cholinergic anti-inflammatory pathway (CAP) first described by Wang et al, 2003 has contemporary interest arising from the COVID-19 pandemic. While tobacco smoking has been considered an aggravating factor in the severity of COVID-19 infections, it has been suggested by some that the nicotine derived from tobacco could lessen the severity of COVID-19 infections. This spotlight briefly describes the CAP and its potential role as a therapeutic target for the treatment of COVID-19 infections using vagus nerve stimulation or selective alpha7 nicotinic acetylcholine receptor agonists.

Perceived Effects Of Covid-19 On K-5 Educators And Learners, Fairbee Mintz

Master of Science in Nursing Theses and Projects

The COVID-19 pandemic disrupted traditional teaching methods at all academic levels bringing about unprecedented changes in the way education was delivered. In-person learning was halted all over the world as educators scrambled to transition to virtual education. The purpose of this Master of Science in Nursing research was to examine the perceived effects of systematic learning changes caused by the COVID-19 pandemic on primary and secondary educators and students as reported by educators. This research will then be applied to implications for future nursing educators and students. Nine K-5 educators were interviewed via Zoom in the spring of 2021 and …

Returning To A New Normal: A Study Examining Student's Perceptions And Experiences Of Campus Reopening During Covid-19, Cara Tonn, Anne Dumadag, Hira Nadeem, Brenda Berumen-Flucker, Priyanka Patel, Hadiza Galadima

College of Health Sciences Posters

Background: Existing research on the mental health and academic impact of the COVID-19 pandemic reports adverse effects during the early stages of the pandemic due to the abrupt campus closures. However, with the relaxation of some restrictions, college students are allowed to return to in-person learning amid new policies. This study aims to assess students' perceptions on several topics related to the pandemic during campus reopening.

Methods: A 22-question cross-sectional survey based on stratified sampling was conducted among 1,025 students at Old Dominion University, and responses were collected via Qualtrics^TM in January 2022. The survey records socio-demographic information, self-reported …

Quantifying The Impact Of Immune History And Variant On Sars-Cov-2 Viral Kinetics And Infection Rebound: A Retrospective Cohort Study, James A. Hay, Stephen M. Kissler, Joseph R. Fauver, Christina Mack, Caroline G. Tai, Radhika M. Samant, Sarah Connolly, Deverick J. Anderson, Gaurav Khullar, Matthew Mackay, Miral Patel, Shannan Kelly, April Manhertz, Isaac Eiter, Daisy Salgado, Tim Baker, Ben Howard, Joel T. Dudley, Christopher E. Mason, Manoj Nair, Yaoxing Huang, John Difiori, David D. Ho, Nathan D. Grubaugh, Yonatan H. Grad

Journal Articles: Epidemiology

BACKGROUND: The combined impact of immunity and SARS-CoV-2 variants on viral kinetics during infections has been unclear.

METHODS: We characterized 1,280 infections from the National Basketball Association occupational health cohort identified between June 2020 and January 2022 using serial RT-qPCR testing. Logistic regression and semi-mechanistic viral RNA kinetics models were used to quantify the effect of age, variant, symptom status, infection history, vaccination status and antibody titer to the founder SARS-CoV-2 strain on the duration of potential infectiousness and overall viral kinetics. The frequency of viral rebounds was quantified under multiple cycle threshold (Ct) value-based definitions.

RESULTS: Among individuals detected …

Insect Cell Expression And Purification Of Recombinant Sars-Cov-2 Spike Proteins That Demonstrate Ace2 Binding, Lucas R. Struble, Audrey L. Smith, William E. Lutz, Gabrielle Grubbs, Satish Sagar, Kenneth W. Bayles, Prakash Radhakrishnan, Surender Khurana, Dalia El-Gamal, Gloria E. O. Borgstahl

Journal Articles: Pathology and Microbiology

The COVID-19 pandemic caused by SARS-CoV-2 infection has led to socio-economic shutdowns and the loss of over 5 million lives worldwide. There is a need for the identification of therapeutic targets to treat COVID-19. SARS-CoV-2 spike is a target of interest for the development of therapeutic targets. We developed a robust SARS-CoV-2 S spike expression and purification protocol from insect cells and studied four recombinant SARS-CoV-2 spike protein constructs based on the original SARS-CoV-2 sequence using a baculovirus expression system: a spike protein receptor-binding domain that includes the SD1 domain (RBD) coupled to a fluorescent tag (S-RBD-eGFP), spike ectodomain coupled …

Type I Ifn Signaling Protects Mice From Lethal Sars-Cov-2 Neuroinvasion., Md Bashir Uddin, Yuejin Liang, Shengjun Shao, Sunil Palani, Michael Mckelvey, Scott C. Weaver, Keer Sun

Journal Articles: Pathology and Microbiology

Multiple organ damage is common in patients with severe COVID-19, even though the underlying pathogenic mechanisms remain unclear. Acute viral infection typically activates type I IFN (IFN-I) signaling. The antiviral role of IFN-I is well characterized in vitro. However, our understanding of how IFN-I regulates host immune response to SARS-CoV-2 infection in vivo is incomplete. Using a human ACE2-transgenic mouse model, we show in the present study that IFN-I receptor signaling is essential for protection against the acute lethality of SARS-CoV-2 in mice. Interestingly, although IFN-I signaling limits viral replication in the lung, the primary infection site, it is dispensable …

The Prevalence Of And Factors Associated With Anxiety And Depression Among Working-Age Adults In Mainland China At The Early Remission Stage Of The Coronavirus 2019 Pandemic, Haixia Xie, Xiaowei Huang, Qi Zhang, Yan Wei, Xuheng Zeng, Fengshui Chang, Shuyin Wu

Community & Environmental Health Faculty Publications

Background: The Coronavirus 2019 (COVID-19) outbreak has led to a considerable proportion of adverse psychological symptoms in different subpopulations. This study aimed to investigate the status of anxiety and depression and their associated factors in the adult, working-age population in Mainland China at the early remission stage of the COVID-19 pandemic.

Methods: An online study was conducted among 1,863 participants in 29 provinces in Mainland China from March 23 to 31, 2020. Their mental health was evaluated by the generalized anxiety disorder scale (GAD-7) and the patient health questionnaire (PHQ-9). Descriptive analysis, Chi-square, and multiple logistic regressions were applied.

Results: …

Effectiveness Of Wechat-Group-Based Parental Health Education In Preventing Unintentional Injuries Among Children Aged 0-3: Randomized Controlled Trial In Shanghai, Yuheng Feng, Xueqi Ma, Qi Zhang, Ruo Jiang, Jun Lu, Kaiyue Chen, Huiping Wang, Qinghua Xia, Jicui Zheng, Jingwei Xia, Xiaohong Li

Community & Environmental Health Faculty Publications

BACKGROUND: Unintentional injuries to children are a major public health problem. The online social media is a potential way to implement health education for caregivers in online communities. Using WeChat, a free and popular social media service in China, this study evaluated the effectiveness of social online community-based parental health education in preventing unintentional injuries in children aged 0-3.

METHODS: We recruited 365 parents from two community health centers in Shanghai and allocated them into intervention and control groups randomly. Follow-up lasted for one year. The intervention group received and followed their WeChat group and a WeChat official account for …

The Impact Of Covid-19 On Healthcare Professionals' Occupational Lives, Javed A. Mohammed, Ronald Kevin Dela Cruz

OCCUPATION: A Medium of Inquiry about Health through Occupation

The COVID-19 pandemic has created a period of instability for billions of people around the world. Healthcare systems have been severely strained by the influx of infected patients, placing much of that hardship on healthcare professionals (HCPs). Occupational therapists, physical therapists, speech-language pathologists, doctors, nurses, respiratory therapists, and other essential personnel—individuals who will be inclusive of the term “HCPs”—continue to struggle with frequent occupational disruption. This paper examines the effects of the COVID-19 pandemic on the occupational lives of HCPs at the national and international levels. The COVID-19 pandemic has drastically increased work-related stress leading to anxiety, depression, burnout, and …

Access, Socioeconomic Environment, And Death From Covid-19 In Nebraska, He Bai, Michelle M. Schwedhelm, John-Martin Lowe, Rachel Lookadoo, Daniel R. Anderson, Abigail Lowe, James V. Lawler, M. Jana Broadhurst, David Brett-Major

Journal Articles: Epidemiology

Our study assesses whether factors related to healthcare access in the first year of the pandemic affect mortality and length of stay (LOS). Our cohort study examined hospitalized patients at Nebraska Medicine between April and October 2020 who were tested for SARS-CoV-2 and had a charted sepsis related diagnostic code. Multivariate logistic was used to analyze the odds of mortality and linear regression was used to calculate the parameter estimates of LOS associated with COVID-19 status, age, gender, race/ethnicity, median household income, admission month, and residential distance from definitive care. Among 475 admissions, the odds of mortality is greater among …

Occupational Health And Safety For Commercial Pilots During The Coronavirus Pandemic, Autumn M. Dawley

OT Student Capstones

BACKGROUND

The aviation industry has been growing with the number of aircraft pilots jumping from 590,038 in 2015 to 664,563 in 2019. With an increasing demand for distribution of cargo, a review of the effects of work-related stressors during the coronavirus pandemic and, further, a solution to increase the health and well-being of individuals in the industry is essential. The Federal Aviation Administration (FAA) addresses fatigue and routinely revises regulations which alleviate job stress; however, the coronavirus pandemic has added new stressors to the aviation industry.

PURPOSE

The purpose of this study was to examine the impact of the pandemic …

Locked In: The Impact Of The Pandemic On Suicide, Evelyn Coile, Tatiana Eversley-Kelso, Eric Shaw, Sara Hamilton

South Atlantic Division GME Research Day 2022

No abstract provided.

Understanding The Mental And Emotional Impacts Of Being A Caregiver Of Socially Isolated Residents During The Covid-19 Pandemic, Chloe Kerrick

Mahurin Honors College Capstone Experience/Thesis Projects

The mental health and emotional wellbeing of individuals has declined in many ways over the course of the COVID-19 pandemic. Some groups have seen more drastic changes in their mental health and emotional wellbeing, especially those working in healthcare. While nearly all healthcare facility workers have experienced an increased burden brought about by the pandemic, long-term care facility workers have been tasked with caring for clients that, for periods of time, experienced complete social isolation. This project will attempt to answer the question of how caring for a group of socially isolated residents over an extended period has affected the …

Identification Of Distinct Immune Cell Subsets Associated With Asymptomatic Infection, Disease Severity, And Viral Persistence In Covid-19 Patients, Xiaorui Wang, Han Bai, Junpeng Ma, Hongyu Qin, Qiqi Zeng, Fang Hu, Tingting Jiang, Weikang Mao, Yang Zhao, Xiaobei Chen, Xin Qi, Mengyang Li, Jiao Xu, Jingcan Hao, Yankui Wang, Xi Ding, Yuanrui Liu, Tianlong Huang, Chao Fang, Changli Ge, Dong Li, Ke Hu, Xianwen Ren, Baojun Zhang, Binghong Zhang, Bingyin Shi, Chengsheng Zhang

Faculty Research 2022

The cell-mediated protective and pathogenic immune responses to SARS-CoV-2 infection remain largely elusive. Here we identified 76 distinct cell subsets in the PBMC samples that were associated with various clinical presentations of COVID-19 using scRNA-seq technology coupled with a deep and comprehensive analysis of unique cell surface markers and differentially expressed genes. We revealed that (TRAV1-2CD8)MAIT cells and (NCAM1CD160)NK cells significantly enriched in the asymptomatic subjects whereas (LAG3CD160CD8)NKT cells increased in the symptomatic patients. We also observed that (CD68CSF1RIL1BCD14)classical monocytes were positively correlated with the disease severity. Moreover, (CD33HLA-DMACD14)classical monocytes and (CLEC10AS100A9)pDC were associated with the viral persistence. The GO …

A Community Effort For Covid-19 Ontology Harmonization, Asiyah Yu Lin, Yuki Yamagata, William D. Duncan, Leigh Carmody, Tatsuya Kushida, Hiroshi Masuya, John Beverley, Biswanath Dutta, Michael Debellis, Zoë May Pendlington, Paola Roncaglia, Yongqun He

Faculty Research 2022

Ontologies have emerged to become critical to support data and knowledge representation, standardization, integration, and analysis. The SARS-CoV-2 pandemic led to the rapid proliferation of COVID-19 data, as well as the development of many COVID-19 ontologies. In the interest of supporting data interoperability, we initiated a community-based effort to harmonize COVID-19 ontologies. Our effort involves the collaborative discussion among developers of seven COVID-19 related ontologies, and the merging of four ontologies. This effort demonstrates the feasibility of harmonizing these ontologies in an interoperable framework to support integrative representation and analysis of COVID-19 related data and knowledge.

The Efficacy And Acceptability Of A Virtual Versus Hybrid Wellness Program On Health Outcomes Among Faculty And Staff At A Northeastern University During Covid-19, Elizabeth Tenison

Graduate Research Theses & Dissertations

According to American Psychological Association Work and Well-being Survey of 1,501 U.S. adult workers, 79% of employees reported negative impacts of work-related stress, including lack of interest (26%) and effort (19%) at work. Workplace wellness programs offer a means to alleviate stress among employees. The research explored the perceived acceptability and efficacy of a virtual versus hybrid wellness program and some specific health outcomes, total cholesterol, BP, and BMI, perceived well-being and stress among faculty and staff at a northeastern university. Participants (n=61) included women (77%), 30-50 years of age (67.7%), and staff (30%) vs. faculty (70%) enrolled in the …

Using The Protection Motivation Theory To Understand The Mental Health Impact Of Surviving Covid-19, Kaprea Johnson, Angel Spence, Yousef Sherif, Dana Brookover, Adrienne White

Adultspan Journal

Due to the widespread effects of COVID-19, mental health professionals need to understand the lived experiences of survivors. Data were collected from YouTube videos (N = 52), which contained firsthand perspectives from COVID-19 survivors. Survivors understood the high stakes of COVID-19, reported the dual threat to physical and mental health, entered “survival mode,” and had both positive and negative reflections on the experience. Implications for mental health professionals and future research directions are included.