Medicine and Health Sciences Commons^™

Longitudinal Assessment Of Health-Related Quality Of Life In Adults With Ckd, Owen Ng, Teixeira-Pinto, Anh Kieu, Anita Van Zwieten, Anoushka Krishnan, Kirsten Howard, Wai H. Lim, Jeremy R. Chapman, Simon D. Roger, Michael J. Bourke, Shaundeep Sen, Steven J. Chadban, Carol A. Pollock, Allison Jaure, Jonathan C. Craig, Jean Yang, Germaine Wong

Research outputs 2022 to 2026

Key Points: Dialysis linked with poorer quality of life compared with transplant patients and patients with CKD. Quality of life trends were similar in both domain-specific and overall quality-of-life measures. Background: There are sparse data about the change in health-related quality of life (HRQoL) with the temporal progression of CKD. In this study, we assessed the association between change in CKD stages, overall and domain-specific quality of life and determined the factors that were associated with this change. Methods: Data were sourced from a multicenter study that included 1290 adult patients aged 18 years and older across six centers in …

The Association Of Apolipoprotein E Ε4 With Symptomatic Intracerebral Hemorrhage, Mri Markers And Cognition In Dutch-Type Hereditary Cerebral Amyloid Angiopathy, Maaike C. Van Der Plas, Rosemarie Van Dort, Ingeborg Rasing, Yongxi Long, Erik W. Van Zwet, Matthias J.P. Van Osch, Hamid R. Sohrabi, Kevin Taddei, Samantha L. Gardener, Ralph N. Martins, Steven M. Greenberg, Gisela M. Terwindt, Marianne A.A. Van Walderveen, Marieke J.H. Wermer

Research outputs 2022 to 2026

Background: Apolipoprotein E (APOE) genotype influences the presence, course and severity of sporadic cerebral amyloid angiopathy (sCAA). We investigated the effect of the APOE ε4-allele on clinical and neuroradiological outcomes in mutation-carriers with Dutch-type hereditary (D-)CAA. Methods: Participants with D-CAA from a prospective cohort study, with data collected on history of symptomatic intracerebral hemorrhages (sICH) and vascular risk factors, underwent 3 Tesla magnetic resonance imaging (MRI) scans to assess macrobleeds, cerebral microbleeds (CMBs), cortical superficial siderosis (cSS), enlarged perivascular spaces (EPVS), white matter hyperintensity (WMH) volume and WMH multispot lesions. Global cognition was measured using Montreal Cognitive Assessment (MoCA) and …

A Flexible Wearable Glucose Sensor For Noninvasive Diabetes Screening: Functional Equivalence And Model Interpretability, Wenhan Xie, Wang, Hao Liu, Shuo Chen, Peng Wang, Yumei Han, Xianxiang Chen, Zhen Fang, Zhan Zhao, Guohong Zhang, Xiuhua Guo

Research outputs 2022 to 2026

Real-world evidence for wearable noninvasive glucose monitoring (NIGM) remains limited. To evaluate the functional equivalence of a wearable NIGM device and explore its utility for T2DM and prediabetes screening. In this multicenter study, 12-h daytime glucose profiles obtained by a flexible reverse iontophoresis-based electrochemical sensor were compared with capillary glucose using functional equivalence. Subgroup analyses were conducted. Screening models of T2DM and prediabetes were developed using elastic net and Logistic regression. A total of 135 participants (mean age 35.3 years; 60.0% female) were included, and no serious device-related adverse events were reported. Compared to the capillary measurements, functional equivalence was …

A Supervised, Online, Home-Based Eccentric Resistance Exercise Program For Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease, Kedar S. Deshpande, Nosaka, Aus Molan, Isaac S. Raj, John K. Olynyk, Oyekoya T. Ayonrinded

Research outputs 2022 to 2026

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common non-communicable chronic liver disease worldwide, increasing long-term risk of cirrhosis, type 2 diabetes mellitus, and cardiovascular diseases. Although reducing liver steatosis by increasing physical activity can lower these risks, patients with MASLD often struggle to exercise regularly. We examined the effects of a supervised, home-based, online bodyweight eccentric exercise program on liver and metabolic markers, and physical fitness in patients with MASLD. Methods: Sixteen adults with MASLD (24–91 years) were assigned to an exercise group (n = 9) or a control group receiving lifestyle counselling (n = 7). The …

Collaboration Between People Admitted To Acute Mental Health Units, Their Family Members And Nurses In The Detection Of Mental State Changes And Recovery: A Qualitative Systematic Review, Karen Foster, Coventry, Yvonne Middlewick, Lindsay Smith, Beverley Ewens

Research outputs 2022 to 2026

Mental health nurses can engage with people with mental health challenges and their families due to their presence on acute mental health units. This presence helps to facilitate recovery-focused care within a physically and emotionally safe environment. Mental health care should be person-centred, individualised, and include wherever possible family and other people in the person's support network. The objective of this systematic review was to explore the existing qualitative literature that describes experiences of collaboration between people with lived experience of mental health challenges, their family members, and nurses in relation to changes in mental state during an admission to …

Impact Of Cannabis And Cannabis Legalization On Us Atrial Septal Defect Rates, Albert Stuart Reece, Hulse

Research outputs 2022 to 2026

Atrial septal defect (ASD) affects 1:11.3 children in some US states; however, the antecedents of these trends are yet to be identified. A total of 1882 ASD rates (ASDRs) for 2003–2020 were sourced from the National Birth Defects Prevention Network reports. A total of 406,893 ASDs are reported. Substance (cigarettes, binge alcohol, cannabis, cannabinoids, analgesics, cocaine) exposure data were taken from the National Survey of Drug Use and Health. Income and ethnicity data were derived from the US Census. Adjustment was performed by mixed effects, survey and generalized additive regression. Causal analysis was by inverse probability weighting and E-values. Data …

Influence Of Simulator Physical Fidelity And Immersion On Decision-Making Skill, Presence, And Cognitive Load, Zachariah G. Hoyne, Morris-Binelli, Sean Müller, Benjamin Piggott, Paola Chivers, Evan Dekker

Research outputs 2022 to 2026

In a variety of domains such as law enforcement and sport, virtual reality is being explored to simulate field-based decision-making contexts. 360-degree video virtual reality (360VR) is innovative as it can immerse the user in a simulated environment, present egocentric, stereoscopic vision and allows for head movements to perceive visual information. However, it is unknown whether physical, rather than psychological fidelity, is crucial for performance, and its impact upon cognitive load, relative to immersion. This study investigated simulator fidelity, presence, and cognitive load across immersion (two-dimensional video and 360VR) in an exemplar sport-specific decision-making task. Thirty skilled Australian Rules Football …

3-Deoxyanthocyanidins Inhibit Β-Amyloid Aggregation, Toxicity, And Mitochondrial Dysfunction: Evidence From Mc-65 Cells And Molecular Dynamics Simulations, Rasheed A. Abdulraheem, Ammar U. Danazumi, Philipp Nitschke, Luke Gray Whiley, Abdulrahman Ibrahim Tudu, Ranil Coorey, Zhoyu Li, Prashant Bharadwaj, Vijay Jayasena, Stuart K. Johnson, Ralph N. Martins, W. M.A.D.Binosha Fernando

Research outputs 2022 to 2026

Accumulation of amyloid-beta (Aβ42) senile plaques in the brain is a hallmark of Alzheimer's disease (AD). Although some drug have been approvaled recently, none has demonstrated robust disease-modifying outcome. The 3-deoxyanthocyanidins (3-DXA) and their derivatives represent a more stable class of polyphenols, present at uniquely high concentrations in sorghum grains. Although 3-DXA exhibit strong potential to modulate protein aggregation processes, their effects on AD pathology remain unexplored. In this study, we investigated the inhibitory effects of three 3-DXA derivatives, apigeninidin chloride (AC), luteolinidin chloride (LC), and 7-methoxy apigeninidin (7-MAC), on Aβ42 aggregation and associated neurotoxicity. Thioflavin T fluorescence assay was …

Length And Framing Of Anti-Junk Food Ads Impact Inclinations To Consume Junk Food Among Normal Weight, Overweight, And Adults With Obesity, Ross C. Hollett, Brennen Mills, Stephanie L. Godrich, Julia Butt, Gina S.A. Trapp

Research outputs 2022 to 2026

Background: Unrestricted junk food advertising increases the risk of short-term junk food consumption among viewers. We aimed to estimate the impact of junk food and anti-junk food advertisements differing in length and framing on junk food consumption inclinations. Methods: Adult participants (N = 505) were exposed to a randomly selected junk food advertisement or anti-junk food advertisement and reported their immediate craving and consumption intentions. These responses were separately analysed for two groups based on Body Mass Index (BMI): participants classified as within the normal range (18.5–25), and a combined group with BMI values indicating either overweight (25+) or obesity …

The Effect Of Midwife-Led Continuous Labor Support Care On Delivery Mode And Timely Initiation Of Breastfeeding In Primigravida Women In Northwest Ethiopia: A Hybrid Type I Implementation Study, Mengstu Melkamu Asaye, Aragaw, Eden Bishaw Taye, Kihinetu Gelaye Wudineh, Sara Bayes

Research outputs 2022 to 2026

Midwife-led continuous labor and childbirth support reduces the episiotomy rate and increases the rates of vaginal delivery and early initiation of breastfeeding. However, no studies have yet been conducted in Ethiopia. This study aimed to evaluate the effect of midwife-led continuous labor and childbirth support. A quasi-experimental study involving 419 primigravida women compared an intervention given by trained midwives at two hospitals to routine at two others. Data were collected from July to December 2024 through interviews and record reviews. The McNemar test was used to compare changes, with a p-value of less than 0.05. Midwife-led continuous labor support increased …

Self-Management Challenges And Psychosocial Support Needs In Clean Intermittent Catheterization: A Qualitative Study Of Individuals With Neurogenic Bladder And Caregivers, Lianyu Zou, Xiaomei Wu, Shun Chen, Shuluan Feng, Xiaohua Huang, Weiting Liu

Research outputs 2022 to 2026

Background – Clean intermittent catheterization (CIC) is widely regarded as the preferred approach to bladder management for individuals with neurogenic bladder (NB). Nevertheless, a considerable gap persists between evidence and clinical practice: patients and caregivers frequently encounter self-management barriers that compromise clinical outcomes during CIC. This qualitative study explores these barriers to provide an empirical foundation for developing tailored strategies that improve quality of care. Design – A descriptive qualitative study. Methods – From August to October 2025, a convenience sampling method was employed to recruit 16 participants individuals with NB or their long-term caregivers from the Department of Rehabilitation …

Recombinant Gelonin: Purification And Functional Validation For Electroporation-Assisted Delivery, Eleni Zivla, Giedrė Šilkūnienė, Andrei G. Pakhomov, Mantas Šilkūnas, Olga N. Pakhomova

Knowledge and Creativity Expo

Type I ribosome-inactivating proteins, such as gelonin, are enzymatically potent toxins but are effectively non-toxic under physiological conditions because they are unable to cross the plasma membrane[1]. Pulsed electric fields (PEF) overcome this delivery barrier by transiently permeabilizing the plasma membrane, allowing direct cytosolic entry. This enhances gelonin cytotoxicity by several thousand-fold, highlighting gelonin’s potential as an electrochemotherapy candidate[2]. Here, we present a recombinant gelonin (rGel) expression platform in E. coli with HPLC-based purification that enables reproducible protein production and structure-guided engineering.

The mature gelonin sequence (residues 47–297) was cloned into pET-32a(+) with an N-terminally fused Trx-6×His tag and TEV …

From Eccentric Force To Explosive Output: A Multidimensional Analysis Of Mechanical Efficiency, Neuromuscular Strategy, And Performance Prediction In National-Level Junior Badminton Athletes Undergoing Overload Training, Mariola Gepfert, Kinga Łosińska, Dariusz T. Skalski, Magdalena Prończuk, Izabella Socha, Alicja Markiel, Aleksandra Markowska, Adam Maszczyk, Artur Gołaś

Baltic Journal of Health and Physical Activity

This study aimed to investigate the neuromechanical pathways linking eccentric force production to explosive concentric output during countermovement jumps (CMJ) in national-level junior badminton athletes undergoing a specialized eccentric training program. Objective: 36 male athletes (age 16.5 ± 1.2 years) were quasi-randomly assigned to an experimental group (EG; n=18), which completed a 6-week supervised eccentric overload training in-volving flywheel squats and depth jumps thrice weekly, or a control group (CG; n=18), which maintained their habitual in-season training without additional interventions. Methods: Pre- and post-intervention assessments included CMJ performance measured on a force platform, with detailed analysis of kinetic and temporal …

Application Of The Multi-Theory Model To Determine Predictors Of Initiating And Sustaining Stress Management Behaviors In Undergraduate College Students, Bishoy T. Samuel, Joshua Mann, Michael Welsch, Manoj Sharma, Vinayak K. Nahar

Journal of Public Health in the Deep South

Background: Undergraduate college students face stress and concomitant mental health issues that can be mitigated by proper stress management behavior.

Purpose: This article examines the multi-theory model (MTM) of health behavior as a predictor of change in the primary outcomes of initiation and sustenance of relaxation-seeking behavior in undergraduate college students for the purposes of stress mitigation. The two main research hypotheses tested were that (a) participatory dialogue, behavioral confidence, and change in physical environment have statistically significant effects on initiation of behavioral change, and (b) emotional transformation, practice for change, and change in social environment have statistically significant effects …

Farmers Markets And Produce Purchasing Behaviors Among University Faculty And Staff, Kritika Gupta, Laurel Lambert, Jangwoo Jo, Selby Rebecca Entrekin, Georgianna Mann

Journal of Public Health in the Deep South

Background: This study explores produce purchasing criteria (PPC) and produce purchasing frequency (PPF) among university faculty and staff, a population often underrepresented in dietary behavior research.

Purpose: To identify distinct PPC profiles among university faculty and staff and examine how these profiles are associated with PPF and farmers market usage, while also assessing the role of demographic and behavioral factors in shaping these relationships.

Methods: Using a 29-item online survey administered to faculty and staff at a southern United States university (N = 175), three distinct PPC clusters were identified: health/label conscious, utilitarian, and no-specified-criteria consumers. Statistical analyses — including …

Telemedicine Kiosks: Can Technology Solve Rural Mississippi's Healthcare Crisis?, Babu George, Martha Ravola

Journal of Public Health in the Deep South

Background: Mississippi’s rural counties face hospital gaps, clinician shortages, and limited broadband/device access that collectively delay care and constrain telehealth uptake.

Purpose: This paper assesses whether telemedicine kiosks can improve rural healthcare access in Mississippi while also supporting viable local entrepreneurship and community development.

Methods: A conceptual, policy-and-market analysis integrated narrative literature synthesis, secondary data and policy review, and 5-year financial modeling under two cost-allocation scenarios: an Operator Model (subscription fees covered by partners/grants) and a Network Model (subscription fees borne by the kiosk operator).

Results: Kiosks with embedded connectivity and diagnostic peripherals can deliver device-independent virtual care and directly …

Promoting A Culture Of Academic Integrity In The Context Of Artificial Intelligence: Lessons From One School Of Public Health In The Southeast, Gregory Pavela, Lindsay C. Aycock, Mercy Aula, Angela Sullivan, Matthew Fifolt

Journal of Public Health in the Deep South

No abstract provided.

Physical And Physiological Profiles Of Competitive Fencers: A Systematic Review And Meta-Analysis Of Strength, Power, Endurance, Agility And Asymmetry, Joanna Motowidło, Miłosz Drozd, Petr Stastny, Dariusz T. Skalski, Izabella Socha, Adam Maszczyk

Baltic Journal of Health and Physical Activity

Background: Evidence on lower-limb strength, explosive power and bilateral asymmetry in competitive fencing is fragmented, and the relative impact of general neuromuscular capacity versus targeted training interventions remains unclear. The aim of this systematic review and meta-analysis is to provide a multidimensional, evidence-based synthesis of data on strength, power, and bilateral asymmetry of the lower limbs in professional fencers. Materials and methods: Following PRISMA 2020 (PROSPERO CRD420251041007), six databases were searched by 31 January 2025. Forty studies of fencers aged ≥ 12 years met the inclusion criteria. Three domain-specific random-effects meta-analyses (DerSimonian–Laird) were conducted: (1) integrated strength and power across …

Differential Treatment Responses Among Comorbidity-Based Subgroups In Individuals With Autism Spectrum Disorder And Clinical Epilepsy, Jenna E. Franklin, Richard E. Frye Md, Phd

Cumberland Medica

Children with Autism Spectrum Disorder (ASD) have elevated rates of epilepsy, seizures, and abnormal electroencephalograms compared to the general population. Many also experience co-occurring comorbidities, which have been associated with epilepsy severity. Although various treatments have shown improvements in seizures and ASD symptomatology, there is limited research on how treatment effectiveness varies by comorbidity profiles. In this study, we characterized individuals with ASD and clinical seizures into specific patient cohorts based on comorbidities and evaluated the responses to traditional antiepileptic drugs (AEDs), non-AED seizure treatments, and non-traditional ASD interventions. Data were collected from a parent-reported, cross-sectional survey previously used to …

Perspective In Biomedical Sciences Field: Education And Career, Fitra Adi Prayogo, Mellyaning Oktaviani Sonya Kirana Sari, Isy Royhanaty, Poppy Fansisca Amelia, Heni Wijayanti, Ni Nyoman Maryaningtyas Adinatha, Dyah Wulandari, Anto Budiharjo

Chulalongkorn Medical Journal

Abstract

Background: The biomedical sciences represent a dynamic and multidisciplinary field pivotal to advancing human health through research, education, and innovation.

Objective(s): This review explores the evolving landscape of biomedical education and career pathways, driven by technological advancements, interdisciplinary integration, and global health demands.

Methods: We examine the distinctions between biomedical science, biomedicine, and biomedical engineering, highlighting their historical origins and contemporary roles. The education and career trajectories of biomedical laboratory scientists (BLS) are analysed, emphasising diverse competencies, core curricula, and the impact of regional policies on professional qualifications. Emerging trends and ethical/regulatory challenges are discussed.

Result(s): Key trends include …

Sequential Presentation Of Diabetic Ketoacidosis, Acute Ischemic Stroke, And St-Elevation Myocardial Infarction: A Case Report, Ichlasul Mahdi Fardhani, Putu Aditya Darmawan Kuntadi, Hammam Arif Shabri, Muhammad Isra Rafidin Rayyan, Zarrah Yuniar Qolbi Harris, Tristi Lukita Wening, Azham Purwandhono

Chulalongkorn Medical Journal

Cardio-cerebral infarction (CCI), the simultaneous occurrence of acute ischemic stroke (AIS) and acute myocardial infarction (AMI), is a rare and life-threatening emergency. Management becomes even more challenging when accompanied by metabolic complications like diabetic ketoacidosis (DKA). We report a case of a 45-year-old man with hypertension and a chronic smoking history, found unresponsive with right-sided hemiparesis. He was last seen well six hours before arrival. On examination, he was hypertensive, tachypneic, had a ketotic breath odor, GCS 12, and NIHSS 15. Laboratory results confirmed DKA, with a random blood glucose of 412 mg/dL and metabolic acidosis. Non-contrast brain CT revealed …

Malignant Transformation Of Giant Epidermal Cyst In The Gluteal Region - A Case Report, Xin Zen Ong Dr., Wan Mokhzani Wan Mokhter Mr., Jing Wen Loh Mr., Ruhana Amirah Abdul Halim Dr.

Chulalongkorn Medical Journal

Epidermal cyst is a very common cutaneous lesion. Giant epidermal cyst is defined by its size of more than 5 cm in diameter. Buttock is an unusual site for epidermal cyst. Malignant transformation of epidermal cyst is an exceedingly rare phenomenon. Clinicians should be vigilant of such entity especially in giant epidermal cyst despite a seemingly benign imaging finding. Long term outcome of surgery for such tumor remains an uncertainty.

Artificial Intelligence Decision Support In Automated Breast Ultrasound: Improving Diagnostic Accuracy And Reducing Unnecessary Biopsies, Chayaporn Hasdiseve, Jenjeera Prueksadee

Chulalongkorn Medical Journal

Background: Emerging roles of artificial intelligence support in breast imaging leads to improved radiologists’ performance

Objective: To assess the diagnostic performance of the artificial intelligence decision support in the evaluation of breast masses using automated breast ultrasound (ABUS).

Methods: 182 patients (415 breast masses) who received ABUS were included. Two readers, including the experienced breast radiologist (reader1) and the breast imaging fellow (reader2), separately reviewed the ABUS images and the artificial intelligence decision support according to the ACR BI-RADS 5^th edition.

Results: All of the 415 masses; 395 masses (95.2%) were benign and 20 masses …

Effect Of Music Therapy On Biophysical Profile And Oxygen Consuption In Preterm Babies In A Rural Hospital., Mahaveer Singh Lakra, Roshan Prasad, Ashwini Lakra, Amar Taksande, Revat J. Meshram, Sagar Karotkar, Mayur Wanjari

Chulalongkorn Medical Journal

Introduction: Music therapy in preterm babies helps in early weight gain, stabilization of heart and respiratory rates, and affect the biophysiological profile. It has a beneficial effect on oxygen consumption and hospital stay. Objectives: This study aimed to assess the effect of music therapy on biophysical profile and oxygen requirement in preterm babies. Methodology: The present comparative, observational study was carried out in the department of neonatology, a rural tertiary care hospital, Sawangi Meghe, Wardha, Maharashtra, India, for one year. All the relevant data was collected and analyzed using the prevalidated Performa. Results and observations: The male-to-female ratio both …

Performance And Cost Comparison Of A Rapid Diagnostic Test For Malaria And Microscopy. A Cross-Sectional Diagnostic Study, Abubakar Sunusi Ishak, Habibu U. Isgogo, Abubakar A. Lawan, Yuda Chongpison

Chulalongkorn Medical Journal

Background: The shift from traditional microscopy to rapid diagnostic tests (RDTs) for malaria diagnosis is gaining popularity, especially in resource-limited settings with unstable electricity and limited expertise. However, trust issues arise due to the inconsistent performance of different RDT kits.

Objectives: This study identified the variations in performance and cost of an RDT brand for malaria among different population demographics: pregnant women, young children, and adults, when compared with microscopy as a gold standard.

Method: The research was carried out in northwestern Nigeria and involved 360 participants stratified into 3 groups: children (5–17 years), adults (≥ 18 years), and pregnant …

Clinical Characteristics Of Cystic Biliary Atresia, Kanokrat Thaiwatcharamas, Sinobol Chusilp, Katawaetee Decharun, Pachareeporn Tanming, Nimmita Srisan, Paisarn Vejchapipat

Chulalongkorn Medical Journal

Background & Objective: Cystic biliary atresia (BA) is a unique form of BA. Our objective was to review the clinical characteristics of cystic BA in order to better understand its nature.

Methods: We retrospectively reviewed all infants diagnosed with cystic BA during January 2005 to December 2019. The diagnosis of BA was confirmed in all cases by laparotomy. Clinical data, pre-operative laboratory and imaging, intraoperative findings, and post-operative outcome were recorded. Data were expressed as mean and SD.

Results: There were 14 cystic BA patients out of the 227 BA patients (6.2%) during the studied period. The mean pre-operative ultrasound …

Superior Mediastinal Cut-Off Measurements In Chest Radiographs For Screening Of Silent Thoracic Aortic Diseases, Kantheera Leesmidt, Boonyarit Sintuvikaiwong, Apichaya Sripariwuth

Chulalongkorn Medical Journal

Objective: To determine cut-off values for superior mediastinal width and the mediastinal width-to-thoracic cage ratio from chest radiographs for the early detection of unrecognized thoracic aortic diseases. Additionally, this study aims to enhance diagnostic strategies for identifying aortic abnormalities.

Materials and Methods: This retrospective analysis included 152 subjects who underwent both computed tomography angiography (CTA) of the thoracic aorta and chest radiograph between April 2007 and January 2021. Superior mediastinal width was measured at 3 levels on chest radiographs. Thoracic CTA findings were categorized into normal and abnormal groups, the latter comprising aortic dissection, intramural hematoma, penetrating atherosclerotic …

Aircraft Wastewater Surveillance As A Tool For Monitoring Disease In The Pacific, Carla J. Eaton, Joanne R. Chapman, Brent J. Gilpin

Pacific Journal of Health

Wastewater surveillance is a powerful tool for monitoring infectious diseases within a population. However, as most wastewater surveillance relies on interconnected wastewater networks to provide samples representative of the population, many Pacific Islands have been excluded from benefiting from this tool due to their lack of reticulated sewerage systems. Many diseases of concern for the Pacific are detectable in wastewater even though individuals may be asymptomatic. We investigated whether analysis of wastewater from aircraft arriving in New Zealand from Pacific Island nations could be used as a proxy for in-country surveillance. Flights from the Pacific arrive in Auckland daily, with …

Integrating Artificial Intelligence Into Fnp/Dnp Simulation To Enhance Clinical Competency, Doris K. Gonzales

SACAD: Scholarly Activities

Abstract  

This poster presents a theoretically grounded, AI-integrated simulation program design structured across 3-4 semesters of Family Nurse Practitioner (FNP) and Doctor of Nursing Practice (DNP) education. This program is designed to support the development of clinical judgment and diagnostic reasoning among FNP students. Guided by Tanner’s Clinical Judgment Model and Roy's Adaptive Model as Theoretical Framework. The program addresses identified gaps in differential diagnosis and role transition from Registered Nurse (RN) to FNP practice. A needs assessment informed the development of a semester-sequenced curricular framework integrating AI-supported simulation across four semesters. The proposed design illustrates how progressive simulation experiences …

Faktor Risiko Perdarahan Gastrointestinal Pada Pasien Dengan Sindrom Koroner Akut: Sebuah Tinjauan Sistematis, Assyadilla Kirana Setyobudi, Amie Vidyani, Jonathan Christianto Sutadji, Lady Aqnes Kurniawati, Kevin Fernando Suhardi

Jurnal Penyakit Dalam Indonesia

Introduction. Gastrointestinal bleeding (GIB) is a serious but potentially preventable condition. Its symptoms include hematemesis, hematochezia, and melena. Risk factors for GIB include medications such as antiplatelets and anticoagulants, which are standard treatments for acute coronary syndrome (ACS). GIB is strongly associated with ACS and represents the most common bleeding complication in these patients. This study aimed to systematically review the factors contributing to GIB in patients with ACS.

Methods. Relevant articles were retrieved from PubMed, ScienceDirect, Springer, and EBSCO databases, covering studies on GIB risk factors in ACS patients published between March 31, 2003, and March 31, …