Medicine and Health Sciences Commons^™

Moving A Maxillary Incisor Across The Midline For Substitution Of Contralateral Missing Incisor In A Multiple Anterior Teeth Missing Patient, Ling-Yu Huang, Chun-Liang Kuo, Chun-Hsiu Yang, Ting-Wei Liu

Taiwanese Journal of Orthodontics

Loss of permanent maxillary incisor causes a significant esthetic problem, and there are various treatment options for rehabilitation. Moving the contralateral tooth across the facial midline for substitution of missing tooth is a possible treatment alternative for closing the maxillary anterior space.

This report presents an unusual treatment for a bimaxillary protrusion patient who typically requires premolar extraction to improve the convex profile. However, due to multiple missing anterior teeth, the left maxillary central incisor was moved across the facial midline to substitute the absent contralateral tooth, resulting in an improved profile after treatment.

The case was an 18-year-old female …

Establishment Of Cephalometric Norms Using Tetragon Analysis In Nepali Adults With Normal Skeletal Relationship, Rashmi Bhattarai, Rabindra Man Shrestha, Jyoti Dhakal

Taiwanese Journal of Orthodontics

Introduction: Cephalometric analysis is a cornerstone in orthodontic diagnosis and treatment planning, enabling precise evaluation of craniofacial structures. Among the various methods, Tetragon analysis offers a unique visual approach to evaluate the maxillo-mandibular relationship. This is based on two geometric constructs, the tetragon representing the maxillo-dento-mandibular complex and the trigon, a complimentary triangle situated above it. Considering the significant genetic and environmental variations in craniofacial development, cephalometric norms established for one population may not be applicable to others.

Objective: This study aimed to establish normative cephalometric values for Tetragon analysis among Nepali adults with normal skeletal relationships.

Materials and Methods: …

Comparative Evaluation Of Trueness And Precision Of Intraoral Scanners For Maxillary Casts In Cleft Lip And Palate: A 3d Study, Rattiya Chuacharoen, Prajak Jariyapongpaiboon, Kaviya Kanokpongsak

Taiwanese Journal of Orthodontics

Objectives: The purpose of this study was to compare the trueness and precision of 5 different intraoral scanning devices in maxillary cleft lip and palate (CLP) models. Material and Methods: One complete unilateral and one complete bilateral CLP model were each scanned by TRIOS E4, a laboratory scanner, and recorded in a standard tessellation language (STL) file as a reference scan. These models were then scanned using five different intraoral machines: TRIOS 4; Straumann Virtuo Vivo; Medit i500; Aoralscan 3; and Panda P2. Each CLP model was scanned 10 times, and the files were saved as test scans. …

Occupation, Displacement, And Violence In The West Bank: A Retrospective Analysis Of Data From 2014-2024, Sarah Aly, Fatima Mossolem, Ayeh Khalil, Tushara Surapaneni, Abd Al-Rahman Traboulsi, Waleed Aldadah, Eleanor Reid, Shakoor Hajat

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Israeli settlement expansion in the West Bank has intensified violence in the occupied Palestinian territories (oPt). This violence escalated after attacks by Hamas on Israel on 7 October 2023 and the subsequent military campaign in Gaza. This study examines the possible impacts of military and land occupation on displacement, injuries, and deaths in the West Bank. This cross-sectional observational study analyses casualties and displacement data in the West Bank and Israel from May 1, 2014, to June 30, 2024. Sources include the United Nations Office of Coordination of Humanitarian Affairs, Statista, and the Palestinian Central Bureau of Statistics. Death and …

Ai-Based Classification Of Pediatric Breath Sounds: Toward A Tool For Early Respiratory Screening, Lichuan Liu, Wei Li, Beth Moxley

Faculty Scholarship-Nursing

Context: Respiratory morbidity is a leading cause of children’s consultations with general practitioners. Auscultation, the act of listening to breath sounds, is a crucial diagnostic method for respiratory system diseases. Problem: Parents and caregivers often lack the necessary knowledge and experience to identify subtle differences in children’s breath sounds. Furthermore, obtaining reliable feedback from young children about their physical condition is challenging. Methods: The use of a human–artificial intelligence (AI) tool is an essential component for screening and monitoring young children’s respiratory diseases. Using clinical data to design and validate the proposed approaches, we propose novel methods for recognizing and …

Organ Of Corti Macrophages: A Distinct Group Of Cochlear Macrophages With Potential Roles In Supporting Cell Degeneration And Survival, Mengxiao Ye, Celia Zhang, Dalian Ding, Guang-Di Chen, Henry J. Adler, Rania Sharaf, Bo Hua Hu

Pacific Faculty Work

Macrophages are the primary immune cells in the cochlea, essential for maintaining cochlear homeostasis and orchestrating inflammatory responses to pathological events. Although these cells have been found in various parts of the cochlea, their presence in the organ of Corti, a critical structure for acoustic sensing, remains poorly understood. The present study was designed to examine macrophage responses to ototoxic drug-induced cochlear damage and age-related cochlear degeneration, with a particular focus on the pathological conditions that trigger macrophage recruitment into the organ of Corti. We used a model of ototoxicity induced by cyclodextrin, a cyclic oligosaccharide known for its ability …

Pulse: Full Issue Download

Quill & Scope

Dear Readers,

I am the soothing beat you hear when your head hits the pillow at night.
I am louder in the silence when you want to be alone with your thoughts.
I am not just a measurement made up of red pixels on a screen.
I keep you alive.
Steady. Persistent.
Who am I?

Pulse. It is one of the first things we check for life. It’s the subtle thrill beneath the surface that reminds us we are here, and we are moving forward. In medicine, the pulse is not just a vital sign; it’s a symbol of …

Why Gen Z Is More Anxious Than Ever? Turning To Social Chats For Answers, Yi Luo, Jin-A Choi, Bond Benton

College of Communication and Media Scholarship and Creative Works

As social media has evolved into a prominent part of Gen Z’s social interaction, this study attempted to enrich our current understanding of Gen Z’s mental health struggles through their conversations surrounding anxiety on social media. Highlights of the findings included the following. First, the overwhelming presence of fear (83%) illustrates that anxiety is an emotionally draining experience for many Gen Z users. The use of emotionally charged language to publicly share their struggles with anxiety reflect increasing self-awareness and a cultural shift toward normalizing mental health conversations. Second, the open, candid conversations on anxiety indicate that anxiety is experienced …

Plane Xanthoma, Connor A. Sheehan, Theresa N. Tran, Jason B. Lee, Jeffrey Y. Liu, Sylvia Hsu

Department of Dermatology and Cutaneous Biology Faculty Papers

No abstract provided.

Factors Affecting Production Of Scopulariopsis Brevicaulis Spores For Use In Self-Healing Concrete, Lu-Kwang Ju, Ahsanul Kabir Sumon

University Research

Concrete durability is compromised by its susceptibility to cracking, necessitating innovative solutions like self-healing concrete (SHC). Scopulariopsis brevicaulis is capable of biomineralization and its spores were found to hold high potential for use in SHC. Realizing this potential requires clean and effective production of S. brevicaulis spores, which remains unexplored. Here the factors and processes conducive to high productivity of S. brevicaulis spores were investigated. Suitability of cheap, renewable soy-based substrates: soy molasses (SM), soy hull (SH), and soy flour (SF) were first evaluated, and SH was found suitable. The comparison of SH-based solid-state fermentation (SSF) with submerged fermentation (SmF) …

The Use Of Topical Vapocoolant Spray In Pediatric Er Patients Receiving Needlesticks, Kileigh Futgett Bsn, Rn, Adriana Hinkle Bsn, Rn, Kayla Mruk Bsn, Rn, Makenna Patterson Bsn, Rn

Vizient/ AACN Nurse Residency Program™ EBP Projects

No abstract provided.

Under The Ocean To Ocean Bridge: California In The Distance, Ivan Dominguez

Quill & Scope

Arizona, 2024

Does Practice Make Perfect? Examining The Impact Of Text-Based Reminders On Adherence In The Helping Our Toddlers, Developing Our Children’S Skills Program, Lauren Patrusky

USF Tampa Graduate Theses and Dissertations

Disruptive behavior disorders (DBDs) are prevalent in approximately 17% of children ages birth to 5 years (CDC, 2023). DBDs can significantly impact a child’s learning, social-emotional wellbeing, and ability to develop and maintain healthy relationship (CDC, 2023). Behavioral parent training (BPT) has been proven effective in reducing disruptive behavior and improving parent-child relationships. However, many families do not fully engage in treatment, leading to poor outcomes for both the child and the family. Chacko (2016) describes BPT engagement as enrolling in treatment, attending weekly sessions, participating in group discussions or role plays in sessions, practicing skills between sessions, and completing …

Mediating Role Of Self-Efficacy In The Association Between Fatigue And Depressive Symptoms In Females With Rheumatoid Arthritis, I-Yu Hsiao, Hanoch Livneh, Chieh-Tsung Yen, Ming-Chi Lu, Wei-Jen Chen, Tzung-Yi Tsai

Counselor Education Faculty Publications and Presentations

Background and Objectives: Extant research on the relationship between fatigue and depression in people with rheumatic diseases portrays a divergent picture. While caring for persons with this medical condition, one issue that represents individual confidence in carrying out specific tasks, namely self-efficacy level, has attracted significant attention. Yet, the information regarding whether self-efficacy may pose a clue linking these two major symptoms is still unknown. The aim of this study, therefore, is to examine whether self-efficacy mediates the association between fatigue and depressive symptoms among persons with rheumatoid arthritis (RA). Materials and Method: A cross-sectional study of 224 …

Core State Injury Prevention Program Listening Sessions Report June 2025 Report, Camille Velarde, Yvonnie Baik, Elena Martinez, Theresa Cruz

Reports & Documents

Background: Injury and violence remain pressing public health challenges in New Mexico, particularly in rural and underserved communities. To inform prevention strategies, the University of New Mexico Prevention Research Center partnered with the New Mexico Department of Health and local organizations to conduct community listening sessions focused on upstream approaches addressing shared risk and protective factors.

Methods: Four listening sessions were conducted in 2025 with stakeholders from county health councils and community organizations. Using a rapid qualitative analysis approach, researchers analyzed participant perspectives on local injury and violence concerns, familiarity with upstream frameworks, and communication preferences.

Results: Participants identified overlapping …

A Conditional Point Cloud Diffusion Model For Deformable Liver Motion Tracking Via A Single Arbitrarily-Angled X-Ray Projection, Jiacheng Xie, Hua-Chieh Shao, Yunxiang Li, Shunyu Yan, Chenyang Shen, Jing Wang, You Zhang

Faculty, Staff and Student Publications

Objective. Deformable liver motion tracking using a single x-ray projection enables real-time motion monitoring and treatment intervention. We introduce a conditional point cloud diffusion (PCD) model-based framework for accurate and robust liver motion tracking from arbitrarily angled single x-ray projections. Approach. We propose a conditional PCD model for liver motion tracking (PCD-Liver), which estimates volumetric liver motion by solving deformable vector fields (DVFs) of a prior liver surface point cloud, based on a single x-ray image. It is a patient-specific model of two main components: a rigid alignment model to estimate the liver’s overall shifts, and a conditional PCD …

Pharmaceutical Innovation Through Computational Drug Design: A Comprehensive Exploration, Manasa Chandramouli, Madhusudhan Heggadadevanakote Surendra

Makara Journal of Science

Chemical biology and computer-aided drug design (CADD) are crucial for identifying and optimizing lead molecules in drug development. Chemical biology is employed to determine the biological function of the target and the mode of action of a chemical modulator. At the same time, in CADD, promising candidate medications are identified based on the structure of the target or known bioactive ligands. Structure-based and ligand-based drug designs should be used in tandem, and their integration with experimental methods can considerably accelerate drug design. Furthermore, the use of CADD along with conventional experimental approaches increases the efficiency and accuracy of the discovery …

Correction: Identification Of A Fusobacterial Rna-Binding Protein Involved In Host Small Rna-Mediated Growth Inhibition, Pu-Ting Dong, Mengdi Yang, Jie Hu, Lujia Cen, Peng Zhou, Difei Xu, Peng Xiong, Jiahe Li, Xuesong He

Faculty, Staff and Student Publications

No abstract provided.

Synthesis Of Carboxymethyl Cellulose From Nypa Fruticans For Coating Metformin On Zn-Based Metal-Organic Framework Nanohybrid As A Bionanocomposite Drug Delivery System, Delviani Delviani, Viola Giary Rizkillah Maharani, Putri Nur Shadrina, Tri Warni, Regina Wan Azizah, Indra Lasmana Tarigan, Madyawati Latief

Makara Journal of Science

Diabetes is a common and rapidly spreading disease that affects 6.6% of the world’s population. Metformin hydrochloride (HCl) is an effective oral pharmacological treatment for type 2 diabetes mellitus (T2DM) patients because of its capability to reduce glucose levels and the risk of hypoglycaemia. However, gastrointestinal sensitivities to this drug can cause diarrhoea, nausea, vomiting and stomach ache. An alternative is controlled release technology by coating metformin with carboxymethyl cellulose (CMC) and zinc-metal-organic framework (Zn-MOF) through the encapsulation method. Therefore, this study aimed to coat metformin formulations using CMC in a Zn-MOF to control release into the body and minimise …

Acute Pancreatitis Associated With Scrub Typhus: Report Of Two Cases With A Brief Review Of Literature, Atanu Chandra, Rupak Chatterjee, Nandini Chatterjee, Sugata Dasgupta

Sultan Qaboos University Medical Journal

Acute pancreatitis is an exceptionally rare complication of scrub typhus. We report 2 cases of scrub typhus-associated acute pancreatitis from a tertiary care centre in Kolkata, India. The first case was a 27-year-old male patient, who presented in 2023, with severe epigastric pain a few days after the onset of fever. Laboratory investigations confirmed acute pancreatitis associated with scrub typhus. He had no additional organ involvement and recovered fully with intravenous doxycycline. The second case, reported in 2024, was a 42-year-old female patient who presented with fever, abdominal pain, vomiting and systemic complications, including acute kidney injury, hepatic dysfunction and …

Cannabis Use In Women And Sexual Dysfunction, Becky K. Lynn, Julia D. López, Morgan E. Link, E C. Campian

2020-Current year OA Pubs

No abstract provided.

Mapping Mave Data For Use In Human Genomics Applications, Jeremy A Arbesfeld, Estelle Y Da, James S Stevenson, Kori Kuzma, Anika Paul, Tierra Farris, Benjamin J Capodanno, Sally B Grindstaff, Kevin Riehle, Nuno Saraiva-Agostinho, Jordan F Safer, Jonathan Casper, Maximilian Haeussler, Aleksandar Milosavljevic, Julia Foreman, Helen V Firth, Sarah E Hunt, Sumaiya Iqbal, Melissa S Cline, Alan F Rubin, Alex H Wagner

Faculty, Staff and Students Publications

Background: Experimental data from functional assays have a critical role in interpreting the impact of genetic variants. Assay data must be unambiguously mapped to a reference genome to make it accessible, but it is often reported relative to assay-specific sequences, complicating downstream use and integration of variant data across resources. To make multiplexed assays of variant effect (MAVE) data more broadly available to the research and clinical communities, the Atlas of Variant Effects Alliance mapped MAVE data from the MaveDB community database to human reference sequences, creating an extensive set of machine-readable homology mappings that are incorporated into widely used …

What Drives Clinic Follow-Up After Traumatic Spinal Injury? An Observational Cohort Study From Tanzania, Chibuikem A Ikwuegbuenyi, Julie Woodfield, Romani Roman Sabas, Sean Inzerillo, Noah Willett, Magalie Cadieux, Scott L Zuckerman, Francois Waterkeyn, Halinder S Mangat, Hamisi K Shabani, Roger Härtl

2020-Current year OA Pubs

OBJECTIVES: To evaluate factors associated with clinic follow-up after traumatic spinal injury (TSI) in Tanzania, focusing on demographic, injury-related and hospital variables. We hypothesised that socioeconomic and injury-specific factors would predict follow-up adherence.

DESIGN: Retrospective observational cohort study.

SETTING: Tertiary government referral centre for neurosurgery and orthopaedics in Dar es Salaam, Tanzania.

PARTICIPANTS: 443 adults with TSI admitted between September 2016 and October 2021. Inclusion criteria included survival to discharge and availability of the discharge date. Patients with missing data were excluded.

PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcomes were any clinic follow-up and 1-year follow-up post-discharge. Secondary outcome was …

A Collective Case Study Of How Researchers Describe Their Experiences, Challenges, And Perceived Impact Of Patient Engagement, Lorna M. Richards

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: Patient engagement (PE) in clinical research has become “extensively and internationally recognized as important and gained growing policy attention, supported by scientific evidence” (Al-Tannir et al., 2017, Background section). The proliferation of PE directives has driven the paradigm shift in drug development from a paternalistic approach to a more patient-centric approach influenced by regulatory agencies, funders, and academic initiatives (Bombak & Hanson, 2017). However, too often, PE activities are not well considered for discovering actionable insights but are merely an empty formality. For PE to be meaningful, patient involvement must be planned, supported, and valued by clinical researchers.

Objectives: …

Hypotension-Specific Rapid Response Team Nurse-Geared Protocol, Quennie Xserenity

Walden Dissertations and Doctoral Studies

This doctor of nursing practice (DNP) project was conducted to develop a clinical practice guideline (CPG) to address a gap at a southeastern hospital where frontline nurses often call rapid response teams for severe hypotension without a standard guideline for necessary interventions. Therefore, the practice gap identified at the project site was the lack of a CPG geared for rapid response nurses (RRNs) to use when responding to a call to intervene on a patient with hypotension. RRNs are nurses with advanced clinical training who provide immediate medical care to rapidly hemodynamically declining patients. The guiding question for this DNP …

Staff Education To Educate Healthcare Providers On Effective Communication And Support Strategies For Child Sexual Abuse Victims, Njideka Ajemba

Walden Dissertations and Doctoral Studies

With this project, I sought to enhance the quality of care provided to child sexual abuse (CSA) survivors by improving healthcare providers’ skills in trauma-informed communication and support strategies. The project was undertaken at a large, private behavioral health facility located in the mid-Atlantic region of the United States, where an assessment of the practice environment revealed a critical gap in provider training. This gap often resulted in missed indicators of abuse, limited emotional support, and poor therapeutic outcomes for children affected by sexual abuse-related trauma. To address this, the project implemented a targeted educational intervention grounded in current evidence …

Low Frequency, High Complexity: Assessing Skill Decay In Transesophageal Echocardiography Post-Simulation Training, Enyo Ablordeppey, Emily Terian, Collyn T Murray, Laura Wallace, Wendy Huang, Erica Blustein, Alexander Croft, Ernesto Romo, Mansi Agarwal, Daniel Theodoro

2020-Current year OA Pubs

INTRODUCTION: Resuscitative transesophageal echo (rTEE) is a promising adjunct to cardiac arrest resuscitation. However, it is a high-acuity diagnostic tool that is rarely used in this setting and its safety establishment is limited because of low occurrence. High-acuity, low occurrence skills such as rTEE during cardiac arrest inevitably decay. In this study we examined the content and percentage of rTEE skill decay following simulation-based education (SBE).

METHODS: Resuscitative TEE-naïve emergency physicians (EP) were trained using a combination of clinical exposure, web-based didactics, and monthly hands-on sessions with a high-fidelity rTEE simulator for four months. The COVID-19 pandemic created a natural …

Anti-Transforming Growth Factor-Β Treatment Shows Increased Bone Mass And Strength In A Novel Mouse Model For Osteogenesis Imperfecta Type I, Ellen Busschers, Yuqing Chen-Everson, Mary Adeyeye, I-Wen Song, Emily Busse, Alexis Castellon, Oscar Ruiz, Nicole Meyers, Yangjin Bae, Catherine Ambrose, Brendan Lee

Faculty, Staff and Students Publications

Anti-transforming growth factor beta (TGF-β) is a promising approach for the treatment of osteogenesis imperfecta (OI). To date, preclinical and clinical studies for the use of anti-TGF-β therapy have focused on moderate to severe OI caused by qualitative defects in collagen. However, the majority of OI patients are represented by type I OI. Mutations resulting in the haploinsufficiency of type I collagen is the cause of OI type I in the majority of patients. To study the effect of anti-TGF-β therapy in type I OI, we generated a novel mouse model for OI type I. CMV-CRE mice were crossed to …

Author Correction: Beta Activity In Human Anterior Cingulate Cortex Mediates Reward Biases, Jiayang Xiao, Joshua A Adkinson, John Myers, Anusha B Allawala, Raissa K Mathura, Victoria Pirtle, Ricardo Najera, Nicole R Provenza, Eleonora Bartoli, Andrew J Watrous, Denise Oswalt, Ron Gadot, Adrish Anand, Ben Shofty, Sanjay J Mathew, Wayne K Goodman, Nader Pouratian, Xaq Pitkow, Kelly R Bijanki, Benjamin Hayden, Sameer A Sheth

Faculty, Staff and Students Publications

No abstract provided.

Multimodal Imaging Directs Decision Making In Intraseptal L-Aaoca, Joseph Burns, Lindsay F Eilers, Stephen J Dolgner, Edward J Hickey, Silvana Molossi

Faculty, Staff and Students Publications

Background: Congenital coronary artery abnormalities represent an uncommon class of congenital heart disease with an associated risk of sudden cardiac death. There is a paucity of data for the evaluation and management of affected patients with an intraseptal course.

Case summary: A 27-year-old woman was found to have a single coronary trunk arising from the right sinus with a 2.7 cm intraseptal course of the left main coronary artery. She underwent stress cardiac magnetic resonance and catheterization, to assess for inducible ischemia before surgical repair with transconal unroofing. Her recovery was uneventful, and she remains free of symptoms.

Discussion: Management …