Medicine and Health Sciences Commons^™

Association Of Abo Blood Groups With Dengue Fever And Its Severity: A Study In Surabaya, Indonesia, Sulistiawati Sulistiawati, Linda Dewanti, Ronald Pratama Adiwinoto, Raissa Manika Purwaningtias, Bilqis Inayatillah, Jan Nouwen

Journal of Health Research

Background: Indonesia, a dengue-endemic country, has high morbidity and mortality rates. Dengue infection manifestations vary from asymptomatic to mild to severe. One of the risk factors for infection that plays a role in this severity is blood type. A better understanding of the risk factors for dengue infection is required to prevent and control it.

Methods: This analytical observational cross-sectional study was conducted at three hospitals in Surabaya from March to May 2013. Consecutive sampling included 95 patients aged >12 years with confirmed dengue infection (IgM/IgG positive) and without comorbid severe illness. Data were collected using questionnaires, interviews, and checklists, …

Mental Health First Aid Certification's Impact On Filipino Nurses' Ability To Increase Personal Help-Seeking Behaviors, Self-Awareness Of Health Changes, And Improved Self-Connection, Maria Elena Holguin, Brenda Marshall, Faith Atte, Katherine J. Roberts

School of Nursing Faculty Scholarship and Creative Works

Background

Post COVID-19, almost 50% of nurses reported severe depression, and over 30% moderate to severe anxiety. Nurses from minority racial and ethnic backgrounds, including Filipino nurses, accounted for more than 54% of COVID-related deaths, despite comprising only 24.1% of the nursing workforce. Filipino nurses, making up only 1% of the U.S. population, comprise 4.5 % of the nursing workforce and face significant barriers to seeking mental health services, including stigma, a sense of shame, and adherence to cultural values that view mental illness as unacceptable.

Aim 

To assess the impact of Mental Health First Aid (MHFA) certification among Filipino …

Lost In Translation: How Health Literacy Impacts Pharmaceutical Transactions From Healthcare Professionals To Patients, Grace Nwaege

2025 Fall Honors Capstones Projects - Archive

Health literacy is a core element of public health, involving the ability to access, understand, evaluate, and use information to maintain well-being. In the United States, it aligns with an average reading level of about an eighth grader, which continues to decline over time. As pharmacists serve as the final point of contact in most outpatient settings, their ability to communicate effectively at this literacy level is crucial. This study examines how pharmacies address this challenge using qualitative methods, including health literacy assessments of patient consent forms and stakeholder interviews with pharmacy technicians about resource use. Findings show materials higher …

Exploring The Role Of Astrocyte System Xc– In Excitatory/Inhibitory Balance, Samantha Olivia Sutton

Theses - ALL

Astrocytes play a central role in maintaining excitatory/inhibitory (E/I) balance in the central nervous system by supporting intracellular glutathione (GSH) synthesis and regulating extracellular glutamate. System xc– (Sxc–), an obligate cystine/glutamate antiporter encoded by SLC7a11, couples the import of L-cystine with the export of L-glutamate. It is highly expressed throughout the cortex, hippocampus, striatum, and cerebellum, where its activity provides cystine—the rate-limiting substrate for cysteine-dependent GSH production—and contributes to ambient glutamatergic tone. Although global loss of Sxc– alters seizure threshold and redox homeostasis, whether these effects arise specifically from the loss of astrocytic Sxc– has remained unresolved. This thesis examined …

Dampit Robusta Coffee Effect On The Creatinine Kinase Levels And Muscle Pain Scales Among Sport Enthusiast, M. Fath Alhaqqi Sanis Salamy, Mohammad Fathul Qorib, Lilik Herawati, Rizky Darmawan, M. Izzul Mujahiddin, Salamun Salamun, Ahmed Zaiyan Nahel Salamy, Achmad Yarziq Mubarak Salis Salamy, Moh Nahar Azmi Mohamed, Ain Darojah Siddiq Ramadhan Ramadhan

Folia Medica Indonesiana

Excessive eccentric exercise often results in muscle injury, reflected by elevated serum creatine kinase (CK) levels and delayed onset muscle soreness (DOMS). In Indonesia, coffee consumption after exercise has increased, with Dampit Robusta Coffee (DRC)—a local variety rich in caffeine and antioxidants considered a potential aid for recovery. This study evaluated the effect of DRC consumption on biomarkers of muscle damage and perceived soreness. A single-blind randomized controlled trial was conducted on 20 healthy untrained men aged 20–25 years, allocated into treatment (n = 10) and control (n = 10) groups. The treatment group consumed brewed DRC (≈200 mg caffeine/day) …

Preeclampsia And Preterm Birth As Predominant Factors Of Low Birth Weight: Insights From A Rural Hospital In Indonesia, Sitisalma Amirah Dzakiyyah, Alissa Rahma, Aziza Salsabila, Devi Silvia Agustina, Syarifah Qamariah, Adhi Mahabudi Duarsa, Nareswari Imanadha Cininta

Folia Medica Indonesiana

Low birth weight (LBW) remains a major public health concern in low-resource and rural settings due to its strong association with neonatal morbidity and mortality. This study aimed to identify maternal determinants associated with LBW in a rural hospital in Indonesia. A retrospective cross-sectional review was conducted on 179 singleton deliveries between January 1st and December 31st, 2024, at Alimuddin Umar General Hospital. Maternal age, parity, anemia, preeclampsia, and gestational age at delivery were obtained from medical records and analyzed using bivariate and multivariate methods. Bivariate analysis showed that preterm birth (p < 0.001) and preeclampsia (p < 0.05) were significantly associated with LBW, whereas maternal age, parity, and anemia showed no significant associations. When adjusted for potential confounders in the multivariate analyses, both preeclampsia (p = 0.019; OR = 4.61; 95% CI: 1.29–16.55) and preterm birth (p < 0.001; OR = 14.60; 95% CI: 5.52–38.57) remained independent predictors of LBW. These findings suggest that preeclampsia and preterm birth are the main contributors to LBW in this setting. Strengthening antenatal care, particularly early detection and management of preeclampsia and prevention of preterm birth, may reduce the burden of LBW. Further studies including nutritional, socioeconomic, and antenatal care variables are recommended to identify independent risk factors more comprehensively.

Clinical Outcomes Of Electrosurgery For Management Of Giant Condyloma Acuminata: A Systematic Review, Fortunia Mona Eviani, Maureen Miracle Stella, Arief Budiyanto, Satiti Retno Pudjiati, Alessandro Alfieri

Folia Medica Indonesiana

Giant condyloma acuminata (GCA) is a rare sexually transmitted disease that is locally aggressive with a high recurrence rate. Electrosurgery is a minimally invasive procedure that may be less expensive, quicker, and safer than conventional surgery. This study aimed to review the management of GCA with electrosurgery. We followed PRISMA 2020 guidelines to search and retrieve literature in the following databases: PubMed, ProQuest, Taylor & Francis, ScienceDirect, JSTOR, and SAGE without time restrictions. The study inclusion criteria were original articles that studied the outcome of electrosurgery in GCA. The authors evaluated the risk of bias using the Joanna Briggs Institute …

Hepatocyte-Specific Lrp1 Silencing Exacerbates Brain Amyloidosis Without Compensatory Ldl Receptor Family Involvement, Brian Carson, Josephine Chu, Devaraj V. Chandrashekar, Jerome Garcia, Rachita K. Sumbria, Derick Han

Pharmacy Faculty Articles and Research

Background

LDL receptor related protein 1 (LRP1) is a major hepatic receptor involved in lipoprotein metabolism, protease degradation, transmembrane receptor modulation, and clearance of excess protein, such as Aβ. Decreased expression of LRP1 due to liver injury can impair receptor-mediated clearance, increasing Aβ availability in the periphery. We investigated the effects of hepato-specific silencing of LRP1 on Aβ deposition in the brain. Additionally, other LDL family members (LRP5, LRP6, and LDLR) that may participate in Aβ clearance were monitored in the liver to ensure non-compensatory effects of LRP1 silencing.

Method

4-month-old male double transgenic (APP/PS1) AD mice were injected with …

Too Much Of A Good Thing: Otc Calcium Carbonate Overdose Causing Milk-Alkali Syndrome In A Psychiatric Patient., Alexandra She, Sangay Bhutia, Francis Jenney

PCOM Scholarly Works

BACKGROUND: In the United States, milk-alkali syndrome or calcium-alkali syndrome is the third most common cause of hypercalcemia, after primary hyperparathyroidism and malignancy. Clinically, patients present with a triad of hypercalcemia, acute kidney injury, and metabolic alkalosis. Classically, it has been associated with excessive intake of calcium and absorbable alkali, and recently it has become more common in postmenopausal females who ingest calcium supplements for osteoporosis.

CASE PRESENTATION: Here, we present the case of a 72-year-old Caucasian female with a longstanding diagnosis of bipolar I disorder who presented to the Emergency Department (ED) with a sudden onset of generalized weakness, …

Surgical Treatment Of Post-Traumatic Elbow Stiffness In Pediatric Patients: A Systematic Review And Meta-Analysis, Roya Khorram, Areeb Ahmad, Reza Vafadar, Ronald Joseph Shamus, Surena Namdari, G. Russell Huffman, Amir R. Kachooei

Rothman Institute Papers

BACKGROUND: Post-traumatic elbow stiffness (PTES) has been reported in up to 21% of pediatric patients following elbow fractures and can profoundly compromise a child's function, and independence. The primary surgical approaches include open and arthroscopic arthrolysis, both of which have demonstrated improvements in range of motion (ROM) and functional scores. This systematic review and meta-analysis aims to compare the effectiveness, ROM, and complication rates between open and arthroscopic release in pediatric patients with PTES.

METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were utilized to conduct a systematic review and meta-analysis on surgical treatment for PTES. Comprehensive …

Mapping Research Trends On Mental Health Literacy Among University Students: A Bibliometric Systematic Review, Eko Pramudya Laksana, Muslihati Muslihati, Arbin Janu Setiyowati, Salsabila Kholifahtun Nisa, Muhammad Nur Hudha, Margaret Kehinde Soetan

Jurnal Kajian Bimbingan dan Konseling

Mental health is a global issue that has received increasing attention, particularly among university students. Mental health literacy (MHL) is an important factor in promoting students' psychological well-being through knowledge, attitudes, and the ability to recognize and address mental health problems. This study aims to map the developmental trends of MHL research among university students in order to provide a comprehensive overview of the direction and focus of studies in this field. This research employed a bibliometric literature review approach by analyzing 48 journal articles indexed in the Scopus database and published between 2021 and 2025. The findings indicate that …

Perceptions Of Lumbee Tribe Members On Participating In Diabetes Type Ii Prevention Practices, Jeremy Wesley Lowery

Walden Dissertations and Doctoral Studies

Type II diabetes (DB2) is one of the leading causes of death in the United States, whether directly or as a comorbidity. This is especially alarming for Native Americans, who have the highest DB2 prevalence and death rates when compared to their non-Native American peers. This qualitative phenomenological study explored the lived experiences of Lumbee Tribe members in Robeson County regarding DB2. The health belief model was used as a lens through which to understand and interpret findings. In-person semi-structured audio-recorded interviews were conducted with 12 participants recruited through social media. Data were coded and analyzed using deductive thematic analysis. …

Antifungal Activity Of Nutmeg Mace (Myristica Fragrans Houtt) Ethanol Extract Against Candida Spp., Muhammad Akbar Yandji, Eka Astuty, Fitri Kadarsih Bandjar

Folia Medica Indonesiana

Candida infections are increasingly common worldwide and represent one of the leading causes of death after cardiovascular disease. There are three types of candida that often infect humans, namely Candida albicans, Candida tropicalis and Candida parapsilosis. In the standard treatment used, immunity and side effects of treatment have been found. Therefore, other treatment options are needed, one of which is by using mace (Myristica fragrans Houtt) which is a native plant of Maluku and has secondary metabolite compounds that can be antifungal agents. This study aims to test the ability of ethanol extract of mace nutmeg ( …

Variety Of Study Methods In Ophthalmology Residency, Muhammad Rizqy Abdullah, Evelyn Komaratih

Folia Medica Indonesiana

Effective study methods are critical in ophthalmology residency, which must balance cognitive learning with surgical skill development. This systematic review examined non-surgical cognitive strategies and surgical training techniques to inform curriculum design and enhance resident performance. A structured literature search was conducted in PubMed and Scopus (2016–2025) using keywords (“study method” OR “effective study” OR “learning strategy” OR “educational intervention” OR “training approach”) AND (“ophthalmology residency” OR “resident education”). After screening and applying eligibility criteria, 17 studies were included. Methods were categorized as non-surgical (n = 5) and surgical learning (n = 12). This review revealed that non-surgical strategies, including …

Exploring Ethanol Extract Of Kersen Fruit (Muntingia Calabura L) As Antimicrobial And Antibiofilm, Hafidz Firmanda, Agung Dwi Wahyu Widodo, Manik Retno Wahyunitisari

Folia Medica Indonesiana

Infections caused by microbial biofilms pose a clinical treat in terms of patient morbidity and mortality rates. For potential treatment this study aims to determine antimicrobial and antibiofilm activity of kersen fruit extract (Muntingia calabura L) on Staphylococcus aureus, Escherichia coli, and Candida albicans. This research used true experimental method with posttest only control group design. Using 6 kersen fruit extract concentration and 4 replications. Antimicrobial test used tube dilution method and antibiofilm test used two different scenario, biofilm growth inhibition test and biofilm degradation test. MIC result against Staphylococcus aures and Escherichia coli at extract …

Pathological And Molecular Parameters Show No Significant Association With Residual Cancer Burden In Breast Carcinoma, Fishella Aprista Rahmanti, Willy Sandhika, Lusiani Tjandra

Folia Medica Indonesiana

Residual Cancer Burden (RCB) is a validated scoring system that quantifies the amount of tumour remaining after neoadjuvant chemotherapy (NAC) for breast cancer, providing prognostic information beyond binary outcomes, such as pathologic complete response (pCR). pCR represents a binary endpoint within various NAC response-grading systems, including RCB, rather than a separate reporting system. This study aimed to assess clinicopathological and molecular predictors of RCB class, including histological grade, histopathological type, molecular subtype, and Ki-67 index. A retrospective study was conducted on 68 patients diagnosed with breast carcinoma who underwent NAC. Descriptive statistics and Pearson, Spearman, and chi-square tests were used …

Group Counseling Deactivation Mode To Improve Psychological Well-Being Of Students, Muya Barida, Dian Ari Widyastuti, Yuanita Dwi Krisphianti, Aslina Ahmad, Nurul Hidayati Rofiah, Andriyani Andriyani, Riana Mashar, Emiko Saraswaty

Jurnal Kajian Bimbingan dan Konseling

Life moves dynamically, profoundly impacting adolescents and often causing deep anxiety due to numerous pressures. The gap between expectations and reality frequently exacerbates this anxiety. Ideally, adolescents should be equipped to manage their inner lives to prevent excessive anxiety, and individuals can better manage anxiety if they possess strong psychological well-being. This study aims to improve psychological well-being through a group counseling deactivation mode. The research applied an experimental research method with a one group pretest-posttest design. Participants consisting of junior high school students in Yogyakarta, selected through purposive sampling for their low psychological well-being levels. Data on psychological well-being …

Online Counseling In Improving Achievement Motivation Over The Last Decade: A Bibliometric Review, Shopyan Jepri Kurniawan, Bambang Dibyo Wiyono, Mohd. Aziz Zulazmi

Jurnal Kajian Bimbingan dan Konseling

This research aims to determine online counseling research trends to increase achievement motivation. The method used in this research is bibliometric analysis using VOSviewer. The data used is the Scopus database for the last 10 years. Research findings found that there were 4302 documents that met the specified criteria. The number of online counseling studies increased gradually over the 2013-2022 research period. The largest source of documents comes from 3691 articles. Meanwhile, the annual distribution of 100 or more citations will be the highest in 2022 with 16. The keyword ``achievement motivation'' is not included in the top 10 keywords, …

Development And Evaluation Of The Agitation In Alzheimer's Screener For Caregivers (Aasc): A Clinical Tool To Screen For Agitation., Carolyn Clevenger, W Clay Jackson, Jared Stroud, Malaak Brubaker, Mehul Patel, Iwona Bucior, Emily Bratlee-Whitaker, T Michelle Brown, Sheri Fehnel, Sue Peschin, Jeffrey Cummings, George Grossberg

Ambulatory and Primary Care Articles

OBJECTIVE: Although agitation is a common neuropsychiatric symptom in Alzheimer's dementia, it can be challenging to recognize and diagnose. Caregivers of individuals with Alzheimer's dementia are often the first to encounter agitation behaviors but may struggle to recognize and communicate symptoms to healthcare professionals (HCPs). Here, we describe the development and evaluation of the Agitation in Alzheimer's Screener for Caregivers (AASC), a practical screening tool to identify agitation symptoms and facilitate caregiver-HCP communication.

METHODS: The AASC was developed based on the International Psychogeriatric Association (IPA) criteria for agitation in cognitive disorders, input from multidisciplinary experts, and qualitative interviews with caregivers …

Association Between Vitamin D And Cholesterol In Post-Acne Hypertrophic Scars And Keloids: A Cross-Sectional Study, Yuli Kurniawati, Yulia Farida Yahya, Sarah Diba, Rina Novriani, Hasbiallah Yusuf, Ekta Martgaredta

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Post-acne hypertrophic scars and keloids result from abnormal wound healing within the pilosebaceous unit. Ruptured microcomedones create wounds that can lead to prolonged inflammation, increased collagen synthesis, and fibrinolysis inhibition, resulting in elevated scar tissue in acne lesions. Vitamin D deficiency can lead to prolonged inflammation and damage to dermal collagen. High total cholesterol levels can lead to excessive sebum production, exacerbating inflammation and fibrosis. This study aimed to determine the association between serum vitamin D and total cholesterol levels with scar severity in patients with post-acne hypertrophic scars and keloids.

Methods: This analytical cross-sectional study was conducted at …

Extensive Superficial Dermatomycosis Caused By Cladophialophora Sp., A Deep Mycosis Pathogen: A Case Report, Nikko Vanda Limantara, Agnes Sri Siswati, Flandiana Yogianti

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Superficial dermatomycosis, predominantly caused by dermatophytes, affects approximately 20–25% of the global population. However, non-dermatophytic fungi, such as Cladophialophora species (sp.), can also cause similar cutaneous infections. Although less common, these organisms are particularly concerning in immunocompromised individuals.

Case Illustration: A 66-year-old immunocompromised male presented with widespread pruritic and erythematous patches, initially misdiagnosed as tinea corporis. Despite receiving standard antifungal therapy, his condition persisted. Further investigation through fungal culture identified Cladophialophora sp., which was resistant to common antifungal agents such as fluconazole, itraconazole, and ketoconazole. However, the fungus was sensitive to terbinafine, which has …

The Efficacy Of Tranexamic Acid In Melasma: A Review, Ninda Sari, Rachmah Diana Putri, Syahriani Syahrir, Agustina Agustina, Mikyal Bulqiah

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Melasma is a common acquired pigmentary condition presenting as dark macules or patches on sun-exposed areas of the face. Conventional treatments rely on topical bleaching agents and sun protection, while additional adjuvant options such as chemical peels, dermabrasion, and laser procedures are often applied. However, recurrence is frequent, and overall therapeutic success remains modest, significantly affecting patient quality of life. Recently, tranexamic acid (TXA) has gained attention as a novel therapeutic approach. This review provides an overview of the available evidence on the efficacy of TXA, used as monotherapy or in combination regimens, for the management of melasma. …

Successful Management Of Generalized Pustular Psoriasis With Cyclosporine In Hiv-Infected Patient, Rasinta Ayudya Deltania, Anggun Putri Yuniaswan

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Generalized pustular psoriasis (GPP) can be associated with human immunodeficiency virus (HIV) infection, making its management more challenging and complex. This case report aims to evaluate the effectiveness and safety of cyclosporine in HIV-associated GPP.

Case illustration: A 31-year-old male with a six-year history of HIV on antiretroviral therapy presented with rapidly spreading erythematous plaques with scaling and patches, along with “lakes of pus”, involving 50% of the body surface area (BSA). He reported oral burning, dysgeusia, and odynophagia; tongue Gram stain showed budding yeast and pseudohyphae. The patient was diagnosed with GPP and oral candidiasis in the setting …

Laser And Light-Based Therapy For Hair Growth And Hair Removal, Michelle Wiryadana, Nelva Karmila Jusuf

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Recent advances in laser and light-based technologies have introduced new options for both the stimulation of hair growth for alopecia and the reduction of unwanted hair growth. However, the clinical evidence remains varied, and treatment outcomes are influenced by factors such as device type, wavelength, and individual response. Ongoing evaluation of safety, efficacy, and standardization of treatment parameters is therefore essential.

Discussion: This review provides an in-depth discussion of the principles, mechanisms, safety, and efficacy of lasers in promoting hair growth, as well as on lasers and light-based therapies used for hair removal. The mechanisms of laser-induced hair growth …

Evaluating The Impact Of A Community-Based Prostate Cancer Screening Program, Amy Leader, Kristine Pham, Nicola Cianci, Hannah Knapp, Fatuma Doka, Suzanne Barron, Oleksandr Kolesnikov, Jordan Dehoratius, Katie Bradley, Le'ann Robles, Robert Giamboy, Olivia Dahlgren, Leonard G. Gomella

Kimmel Cancer Center Faculty Papers

BACKGROUND: One out of eight men in the U.S. will be diagnosed with prostate cancer during his lifetime. Black men are more likely to be diagnosed with and die from prostate cancer than other males, contributing to significant prostate cancer disparities. Early detection, often by routine screening, allows for more options for treatment and an increased chance of survival. Barriers to screening contribute to prostate cancer disparities, particularly among those who lack regular access to health care. Community based screening programs may overcome barriers to prostate cancer screening.

METHODS: An urban, NCI-designated cancer center collaborated with a national prostate cancer …

Video Education On The Knowledge Of Cosmetics And Skin Care Contact Dermatitis: A Cross-Sectional Study, Muhammad Rizkinanda Prasetyo, Damayanti Damayanti, Lilik Herawati, Sylvia Anggraeni

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Contact dermatitis is an immunologic reaction to irritants, allergens, and is commonly associated with cosmetics and skin-care products. Limited knowledge of this condition increases the risk of improper product use and delays preventive measures. Therefore, education plays a crucial role in fostering a comprehensive understanding of its etiology and prevention. This study aimed to evaluate the effectiveness of a video-based educational intervention in enhancing women’s knowledge regarding contact dermatitis related to cosmetics and skin-care products.

Methods: This cross-sectional study collected primary data from 100 female academics aged 17–45 at Airlangga University, Surabaya, East Java, Indonesia. Knowledge of contact dermatitis …

Difficulties In Diagnosing Primary Cutaneous Mucormycosis: Excluding Mycobacterium Other Than Tuberculosis, Chinda Liaska Indah, Sri Linuwih Susetyo Wardhani Menaldi, Sondang Pandjaitan Sirait, Sandra Widaty

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Mucormycosis is a rare fungal infection caused by a group of opportunistic fungi from the class Zygomycetes. Primary cutaneous mucormycosis is the most common type of mucormycosis in immunocompetent patients. This study reported a case of primary cutaneous mucormycosis with nonspecific clinical characteristics and various supporting examinations. The patient was successfully treated with in toto excision and oral ketoconazole.

Case Illustration: A 40-year-old female presented with purplish-red spots and painless lumps on the second finger of her right hand, which had been present for a year. She had a history of frequent fish tank cleaning and gardening but …

The Profile Of Skin Cancer Patients At Dr Pirngadi Hospital Medan: A Retrospective Study, Febrina Dewi Pratiwi Lingga, Aisya Indira, Remenda Siregar

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Skin cancer is among the most common malignancies, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma. In Indonesia, it ranks third after cervical and breast cancer. This study aimed to analyze the demographic, clinical, and treatment patterns of skin cancer cases at Dr. Pirngadi General Hospital, Medan, Indonesia from 2019 to 2023.

Methods: A retrospective descriptive study was conducted using medical record data of all skin cancer patients treated from 2019 to 2023. Variables analyzed included age, sex, occupation, lesion site, skin cancer type, and treatment modality. Data were analyzed using univariate statistics and presented …

Effectiveness And Safety Of Moisturizing Wash And Cream In The Treatment Of Elderly Xerosis Cutis, Lili Legiawati, Shannaz Nadia Yusharyahya, Rinadewi Astriningrum, Fathirah Rahmatiah Puteri, Nabila Chalisya Ilyas

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The skin undergoes degenerative and metabolic changes with aging, increasing susceptibility to dermatological conditions. Xerosis cutis, characterized by rough, scaly skin on the lower legs, is the most common cause of pruritus in elderly patients, with a prevalence of 38–85%. Treating xerosis cutis is challenging due to its multifactorial causes, especially in the elderly. Moisturizers remain the primary and most effective treatment, providing convenience and efficacy. This study aimed to evaluate the effects of QV Intensive Moisturizing Cleanser™️ and QV Intensive Cream™️ (Ego Pharmaceuticals, Australia), which contain humectants, emollients, and occlusives.

Case Illustration: This observational case series involved six …

The Recurrence Of Bowen’S Disease After Topical 5% 5-Fluorouracil Cream Application: A Systematic Review, Mohammad Agassi Antoniman, Ika Anggraini

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Bowen’s disease (BD) may develop into cutaneous squamous cell carcinoma (CSCC), which can spread to other parts of the body. 5% 5-fluorouracil (5-FU) cream is commonly used for topical therapy on BD; however, the frequency and duration of treatment per cycle have not been standardized. This systematic review aimed to identify the most effective frequency and duration of 5% 5-FU treatment for achieving complete clearance or minimal recurrence.

Methods: A literature search was conducted using three electronic databases (PROSPERO ID: CRD42024607488): MEDLINE, Cochrane, and Scopus. The articles were selected based on their relevance to the clinical question. Appraisals were …