Medicine and Health Sciences Commons^™

Relationship Between Nontraditional Lipid Parameters And The Risk Of Type 2 Diabetes In Individuals Recovered From Dyslipidemia: A Cohort Study, Yuxian Wang, Zekai Chen, Zhen He, Hailun Qin, Kuangyi Wu, Huancong Zheng, Peng Fu, Zefeng Cai, Weiqiang Wu, Yulong Lan, Dan Wu, Shouling Wu, Youren Chen

Research outputs 2022 to 2026

Aims/Introduction: Lipid profiles are essential for assessing type 2 diabetes (T2D) risk, but individuals who recover from dyslipidemia are often overlooked, leaving their residual risk unclear. This study aimed to evaluate T2D risk in individuals with varying lipid change patterns and investigate the associations between traditional and novel lipid parameters with T2D risk among those recovered from dyslipidemia. Materials and Methods: In this prospective cohort study of the Kailuan Study, 39,283 non-diabetic participants were followed to evaluate T2D risk across lipid change patterns using the Cox proportional hazards models. A subset of 3,850 individuals recovered from dyslipidemia was analyzed to …

The Acute Effects Of Caffeine, Creatine, And Carbohydrate Mouth Rinse Combined With Conditioning Activity On Subsequent Sports Performance: A Systematic Review And Bayesian Meta-Analysis, Yanfeng Li, Bopeng Qiu, Hongyan Kuai, Kongyun Huang, Hengxian Liu, Mingyang Zhang, Mingyue Yin, Yilin Zhang, Hengzhi Deng, Yuming Zhong, Hao Kong, Jun Chen, Kai Xu

Research outputs 2022 to 2026

Background: Post-activation performance enhancement (PAPE) refers to the acute improvement in sports performance following a conditioning activity (CA), commonly used in warm-up protocols and complex training. While CA alone has demonstrated performance benefits, the effects of combining CA-induced PAPE with supplements (e.g., caffeine, creatine, or carbohydrate mouth rinse) remain unclear. Objectives: This study was to (i) assess the effects of PAPE combined with supplements on sports performance and fatigue resistance compared to PAPE + placebo, warm-up + supplements, or warm-up alone, and (ii) synthesize direct and indirect evidence on performance outcomes using network meta-analysis. Methods: Searches were conducted across three …

Enhancing Cardiovascular Risk Prediction In Hypertensive Adults: A 3pm-Based Evaluation Of Insulin Resistance And Arterial Stiffness, Yulong Lan, Zhaogui Wu, Dan Wu, Lingyu Xu, Hongfa Wei, Chutao Wu, Youren Chen, Xiaolan Li, Shouling Wu

Research outputs 2022 to 2026

Objective: Hypertension management remains challenging due to coexisting insulin resistance (IR) and arterial stiffness—two silent yet synergistic drivers of atherosclerotic cardiovascular disease (ASCVD). This study aimed to evaluate their joint impact on ASCVD risk and assess their utility in predictive, preventive, and personalized strategies. Methods: In this prospective cohort study of 30,094 adults with hypertension, IR was assessed using the triglyceride-glucose (TyG) index (calculated as ln [TG (mg/dL) × FBG (mg/dL)/2]) and arterial stiffness via brachial-ankle pulse wave velocity (baPWV). Time-to-event analyses examined their individual and combined associations with ASCVD incidence. Results: Over a median 5.6-year follow-up, 1655 ASCVD cases …

A Scoping Review Of Randomised Controlled Trials Of Vaccines That Recruited Care Home Residents: Lessons For Future Trials, Selvarani Selvarani Subbarayan, Imogen Smith-Dodd, Gabriel Nicolson, Jennifer Kirsty Burton, Janet T. Scott, Seshadri S. Vasan, Susan D. Shenkin, Roy L. Soiza

Research outputs 2022 to 2026

Introduction: Older care home (CH) residents are particularly vulnerable to infections and often experience adverse outcomes. Despite this group being frequently prioritised for vaccinations, trials of vaccines rarely recruit CH residents. Given that the social and biological characteristics of CH residents may influence vaccine effectiveness, it is crucial to test vaccines in this population.

Methods: The Widening Access to Trials in Care Homes project was established to develop best practice guidance on designing and conducting vaccine trials in the CH population. As part of this project, a scoping review following Joanna Briggs Institute methodology was conducted to identify vaccine trials …

Distinct Contributions Of Cerebrospinal Fluid Biomarkers To Cognitive Impairment And Neuropsychiatric Symptoms In Young-Onset Dementia, Wei Hsuan Chiu, Anita M.Y. Goh, Dhamidhu Eratne, Charles B. Malpas, Matthew J.Y. Kang, Wendy Kelso, Mark Walterfang, Dennis Velakoulis, Samantha M. Loi

Research outputs 2022 to 2026

Objective: Young-onset dementia (YOD), defined by symptom onset before age 65, encompasses diverse aetiologies and presents with prominent neuropsychiatric symptoms (NPS) that often accompany or exacerbate cognitive decline. However, the pathological mechanisms linking NPS, cognition, and biomarkers remain unclear. It was hypothesised that relationships between NPS and cognition would be mediated or moderated by cerebrospinal fluid (CSF) biomarker levels in individuals with YOD. Methods: This retrospective, cross-sectional study included 46 participants with YOD (24 with Alzheimer's disease [AD], 22 with non-AD dementias) diagnosed at the Neuropsychiatry Centre, Royal Melbourne Hospital. NPS were measured using the Depression Anxiety and Stress Scale …

Navigating Ethical Complexities In Health Education: Exploring Challenges In Teaching Food And Health, E. Oljans, M. Quennerstedt, D. Barker, A. Caldeborg, V. Varea

Research outputs 2022 to 2026

Teaching food and health may be challenging, especially in classrooms where young people from different cultures, ethnicities, and religions meet. This article explores teachers’ navigation of ethical complexities when teaching food and health in classrooms with immigrant students. Five didactical strategies were identified: (1) The educare strategy, (2) The tiptoeing strategy, (3) The collegial support strategy, (4) The intercultural strategy, and (5) The pluralistic strategy. These didactical strategies are embedded in various educational settings. Our results demonstrate that a further focus on ethical and intercultural competence should be carefully supported and implemented in teacher education and continual professional development programmes …

Sorghum And Sorghum-Based Products: Nutritional Composition, Prebiotic Potential And Health Benefits In Gut Microbiota Interactions, W. M.A.D.Binosha Fernando, Rasheed A. Abdulraheem, Kalmee Pramoda Kariyawasam, Amal Sudaraka Samarasinghe, W. M.Kendrea T. Fernando, Hannah Barnes, Malina Robertson, D. P.W. Jayatunga, B. G.D.N.K. De Silva, Vijay Jayasena

Research outputs 2022 to 2026

Sorghum (Sorghum bicolor L.) is a member of the Poaceae family and is the fifth most important crop globally. Sorghum grains (SGs) are rich in health-promoting macro- and micronutrients and phytochemicals. SGs are commonly consumed as food or as ingredients in food, especially in African countries. Therefore, food products such as ogi, bread and flour have been and are still being developed from SGs to provide nutritional and health benefits. However, the nutritional and prebiotic potential of SGs, especially the pigment pericarps, has not been fully exploited. This review describes micronutrients in different varieties of sorghum and the health benefits …

Towards Equitable Cancer Outcomes For Rural And Remote Communities: Reflections, Lessons And Recommendations, Anna Ugalde, Hannah Jongebloed, Charlene Wright, Helena Rodi, Anna Chapman, Skye Marshall, Drew Aras, Rebecca J. Bergin, Sophie Boffa, Anna Boltong, Michele Conlin, Fiona Crawford–Williams, Carl De Wet, Wasek Faisal, Lan Gao, Harry Gasper, Kate Gunn, Nicolas H. Hart, Theresa Hayes, Florian Honeyball, Elizabeth A. Johnston, Deme Karikios, Nicole Kiss, Lucy Leigh, Patricia M. Livingston, Carmel O'Kane

Research outputs 2022 to 2026

People living in rural and remote areas continue to face significant inequities in cancer outcomes compared to their metropolitan counterparts. Despite advances in cancer control, these disparities persist across the cancer trajectory. This personal view consolidates findings from our Equitable Cancer Outcomes for Rural and Remote Communities series, highlighting survival disadvantages, challenges in measuring and reporting rurality, barriers to implementing evidence-based interventions, and shortcomings in historical policy. We argue for place-based, system-level reform that genuinely partners with rural communities, leverages local strengths, and embeds rural voices in research, policy, and service delivery. Key recommendations include adopting a formal partnership position …

To Discard Or Not To Discard 1pns? A Systematic Review And Meta-Analysis On 291,474 Embryos, T. Lee, F. Qi, K. Peirce, J. Natalwala, V. Chapple, P. J. Mark, K. Sanders, Y. Liu

Research outputs 2022 to 2026

Unlike embryos that display two pronuclei (2PN), monopronucleated (1PN) embryos are assumed to be haploid and can be routinely discarded. Although there are reports of live births after 1PN embryo transfer, the developmental and clinical prognosis of 1PN embryos has not been systematically evaluated. The aim of this review was to elucidate the developmental, clinical and neonatal outcomes of 1PN embryos compared with 2PN embryos. Twenty-four studies met the inclusion criteria. The blastulation rate was lower in 1PN embryos compared with 2PN embryos [risk ratio (RR) 0.50, 95% CI 0.48–0.51]. The live birth rate was lower in 1PN blastocysts when …

High Neuraxial Blockade In A Parturient After Epidural Placement: A Quality Improvement Simulation., Samir Patel, Noah D Le, John Carter, Nick Melott, Andrew Kalnow, Camille D Hawkins, Alexander Luong, Matthias Franzen

Medical Education Articles

Background Epidural anesthesia is a commonly used procedure in obstetrics for managing labor pain, with a potential complication of high neuraxial blockade. Proficiency in performing epidural or spinal anesthesia and promptly recognizing and managing high neuraxial blockade are critical components of anesthesiology residency training. Methods A simulated case was designed involving a 21-year-old female in labor receiving epidural anesthesia. After the administration of local anesthetic, she develops symptoms of nausea, hypotension, and respiratory distress, progressing to high neuraxial blockade. The simulation environment included a labor and delivery suite setup, an epidural cart, airway supplies, a Laerdal SimMan 3G PLUS mannequin …

Treatment Of Ovarian Clear Cell Carcinoma: A Case Of Successful Management With Targeted Therapies., Sydney Pence, Kellie Rath, Aine Clements

Women’s Health Articles

No abstract provided.

Food Allergies And Quality Of Life In Older Adults: Development Of A Food Allergy Questionnaire, Avalon F. Mustafa

UNF Graduate Theses and Dissertations

The United States is experiencing a rapid increase in the number of older adults, yet there is a lack of research on food allergies in this demographic. While there are survey instruments available to study food allergies and quality of life, none of these are tailored to the unique needs of elderly individuals. This study aims to create and validate an on-line survey instrument specifically designed for older adults, focusing on their quality of life in the context of food allergies. The survey will be used to establish a food allergy severity score and a quality-of-life score, enabling comparison between …

Precision Haptics For Rehabilitation: Quantifying Directional Bias And Force Threshold Effects On Motor Learning, Conor J. Nolan

UNF Graduate Theses and Dissertations

Hand rehabilitation represents a critical challenge in modern physical therapy, with significant implications for patients' quality of life and functional independence. Despite technological advancements across healthcare, traditional hand assessment methods often rely on subjective measures or lack task-specific biomechanical assessment capabilities. This thesis investigates the effects of haptic force feedback, handedness, and rotation direction on circle-tracing task completion using a within-subjects factorial design with 20 university participants examining varying resistance levels (0.0N, 0.5N, 1.2N) across different movement configurations using a 3D Systems Touch X haptic device with 0.023mm precision. Results demonstrate that moderate haptic force (0.5N) significantly enhanced spatial accuracy …

Parental Sources Of Nutrition Information And Their Knowledge, Attitudes, And Behaviors: Impact On Children's Dietary Intake In Ages 2-5 – A Cross-Sectional Study, Mara O. Fiorio

UNF Graduate Theses and Dissertations

Objectives: Nutrition in early childhood is critical to long-term health outcomes and parents play a key role in shaping children’s eating habits. This study examined where U.S. parents of children aged 2–5 obtain nutrition information, source credibility, and how parental nutrition knowledge, attitudes, and behaviors (KAB) relate to children’s dietary intake.

Methods: A cross-sectional online survey was completed by 126 parents, recruited via social media and community networks using convenience sampling. The survey assessed parental sources of nutrition information, perceived trustworthiness, nutrition knowledge, feeding attitudes and behaviors, and child dietary intake. Descriptive statistics summarized demographic characteristics and source utilization. Chi-square …