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2025

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Full-Text Articles in Medicine and Health Sciences

Be Faster Community Of Practice To Increase Rapid Initiation Of Antiretroviral Therapy In Houston, Texas: A Pre-Post Intervention Study, Naomi Sequeira, Bich N Dang, Melanie Goebel, Monisha Arya, Avishek Ghosh-Hajra, Kathryn Fergus, Shital M Patel Nov 2025

Be Faster Community Of Practice To Increase Rapid Initiation Of Antiretroviral Therapy In Houston, Texas: A Pre-Post Intervention Study, Naomi Sequeira, Bich N Dang, Melanie Goebel, Monisha Arya, Avishek Ghosh-Hajra, Kathryn Fergus, Shital M Patel

Faculty, Staff and Students Publications

Background: Rapid initiation of antiretroviral therapy (Rapid ART) is a key strategy of the Ending the HIV Epidemic (EHE) initiative. The Baylor College of Medicine Extension for Community Healthcare Outcomes (ECHO) Facilitating Antiretroviral Start Earlier (BE FASTER) program was developed to address this call-to-action. The program uses the ProjectECHO tele-mentoring model as an implementation tool in Harris County, a priority EHE jurisdiction. The authors present results on the acceptability and feasibility of the BE FASTER program.

Methods: Multidisciplinary health professionals from 5 Ryan White Part A funded agencies formed the community of practice. The BE FASTER program included 9 monthly …


Retinol Tracing Within Murine Neural Retina Reveals Cell Type-Specific Retinol Transport And Distribution, Zachary J Engfer, Grazyna Palczewska, Samuel W Du, Jianye Zhang, Zhiqian Dong, Carolline Rodrigues Menezes, Jun Wang, Jianming Shao, Budd A Tucker, Robert F Mullins, Rui Chen, Philip D Kiser, Krzysztof Palczewski Nov 2025

Retinol Tracing Within Murine Neural Retina Reveals Cell Type-Specific Retinol Transport And Distribution, Zachary J Engfer, Grazyna Palczewska, Samuel W Du, Jianye Zhang, Zhiqian Dong, Carolline Rodrigues Menezes, Jun Wang, Jianming Shao, Budd A Tucker, Robert F Mullins, Rui Chen, Philip D Kiser, Krzysztof Palczewski

Faculty, Staff and Students Publications

11-cis-Retinal is essential for light perception in mammalian photoreceptors (PRs), and aberrations in retinoid transformations cause severe retinal diseases. Understanding these processes is crucial for combating blinding diseases. The visual cycle, operating within PRs and the retinal pigment epithelium (RPE), regenerates 11-cis-retinal to sustain light sensitivity. Retinoids are also present in Müller glia (MG), hypothesized to supply 11-cis-retinol to cone PRs and retinal ganglion cells (RGCs). To trace retinoid movement through retinal cell types, we used cell-specific knock-in of lecithin:retinol acyltransferase (LRAT), which converts retinols into stable retinyl esters (REs). Ectopic LRAT expression in murine PRs, MG, and RGCs resulted …


Improved Technical Outcomes With Converting Thrombectomy Techniques After Failed First Pass Recanalization, Hidetoshi Matsukawa, Charles Matouk, Kazutaka Uchida, Sami Al Kasab, Mohammad-Mahdi Sowlat, Sameh Samir Elawady, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Q Wolfe, Ansaar T Rai, Robert M Starke, Marios-Nikos Psychogios, Edgar A Samaniego, Adam S Arthur, Hugo Cuellar, Brain M Howard, Daniele G Romano, Omar Tanweer, Justin R Mascitelli, Isabel Fragata, Adam Polifka, Joshua W Osbun, Roberto Javier Crosa, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Richard Williamson, Pedro Navia, Peter Kan, Reade Andrew De Leacy, Shakeel A Chowdhry, Mohamad Ezzeldin, Alejandro M Spiotta, Shinichi Yoshimura, Ali M Alawieh Nov 2025

Improved Technical Outcomes With Converting Thrombectomy Techniques After Failed First Pass Recanalization, Hidetoshi Matsukawa, Charles Matouk, Kazutaka Uchida, Sami Al Kasab, Mohammad-Mahdi Sowlat, Sameh Samir Elawady, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Q Wolfe, Ansaar T Rai, Robert M Starke, Marios-Nikos Psychogios, Edgar A Samaniego, Adam S Arthur, Hugo Cuellar, Brain M Howard, Daniele G Romano, Omar Tanweer, Justin R Mascitelli, Isabel Fragata, Adam Polifka, Joshua W Osbun, Roberto Javier Crosa, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Richard Williamson, Pedro Navia, Peter Kan, Reade Andrew De Leacy, Shakeel A Chowdhry, Mohamad Ezzeldin, Alejandro M Spiotta, Shinichi Yoshimura, Ali M Alawieh

Faculty, Staff and Students Publications

Background: A higher number of recanalization attempts reduces the efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke secondary to large vessel occlusion (LVO). We assessed the impact of switching EVT techniques after a failed first pass on procedural and clinical outcomes.

Methods: This multicenter international study, conducted between January 2013 and December 2022, included patients undergoing EVT for anterior circulation LVO (internal carotid artery or M1 segments) with failed first pass recanalization. Propensity score matching identified a 1:1 matched cohort of patients in whom EVT technique was changed after a failed first pass and those with the same technique …


Two Unrelated Pseudomonas Aeruginosa Phages Require The Exopolysaccharide Psl For Infection, Kristen Amyx-Sherer, Leila C Awasthi, Amanda Zheng, Anna Johannesman, Michele Leroux, Courtney Reichhardt Nov 2025

Two Unrelated Pseudomonas Aeruginosa Phages Require The Exopolysaccharide Psl For Infection, Kristen Amyx-Sherer, Leila C Awasthi, Amanda Zheng, Anna Johannesman, Michele Leroux, Courtney Reichhardt

2020-Current year OA Pubs

Bacteria commonly protect themselves from a variety of threats by forming biofilms, which are communities of bacteria that are tightly packed together within an extracellular matrix. Biofilm formation has generally been thought to protect bacteria from phage infection. The opportunistic pathogen Pseudomonas aeruginosa produces biofilm matrices that can contain three distinct exopolysaccharides that contribute to the difficulty in treating infected patients. Here, we demonstrate that two diverse P. aeruginosa phages have evolved to exploit this biofilm matrix to access the bacterial cells by both binding to and degrading a major biofilm exopolysaccharide, Psl. We examined the effect of these phages …


Depth-Variant Deconvolution Applied To Widefield Microscopy For Rapid Large-Volume Tissue Imaging, Daniel D Lee, Kevin A Telfer, Mark A J Koenis, Yim K Lee, Kevin W Namink, Brian T Saunders, Heyun Lee, Hailey Kelley, Heather S Ruiz, Joseph P Gaut, Gwendalyn J Randolph, Bernd H Zinselmeyer Nov 2025

Depth-Variant Deconvolution Applied To Widefield Microscopy For Rapid Large-Volume Tissue Imaging, Daniel D Lee, Kevin A Telfer, Mark A J Koenis, Yim K Lee, Kevin W Namink, Brian T Saunders, Heyun Lee, Hailey Kelley, Heather S Ruiz, Joseph P Gaut, Gwendalyn J Randolph, Bernd H Zinselmeyer

2020-Current year OA Pubs

Innovations in 3D tissue imaging have revolutionized research, but limitations stemming from lengthy protocols and equipment accessibility persist. Widefield microscopy is fast and accessible but often excluded from 3D imaging workflows due to its lack of optical sectioning. Here we combine tissue clearing with a commercial depth-variant deconvolution approach that we optimized for large-volume widefield imaging. By implementing prefiltering with z-brick splitting, we achieve subnuclear axial resolution in tissues to a depth of 500 µm in multi-tile scan images. We illustrate the utility of this method in a model of ileitis and to gain a 3D perspective in thick brain …


Belonging Without Borders: A Missionary Kid Reflects On Nursing School, Julia Beth Stamp Nov 2025

Belonging Without Borders: A Missionary Kid Reflects On Nursing School, Julia Beth Stamp

Wisdom & Compassion: The LUSON Journal

This reflective essay examines the experience of pursuing a nursing degree while living far from home as a Missionary Kid. It explores how the absence of close family ties during nursing school intensified feelings of loneliness, challenged motivation, and strained emotional well-being. Interwoven with personal narrative and supported by recent literature, the reflection highlights the way that community— through peers, mentors, and faculty— emerged as a vital source of resilience. The essay argues that resilience in nursing education is not the product of individual grit alone but grows from interdependence and the willingness to seek and receive support. Through recounting …


Sacred Lessons In The Last Moments: Faith Integration And Holistic Nursing, Meredith Lemmi Nov 2025

Sacred Lessons In The Last Moments: Faith Integration And Holistic Nursing, Meredith Lemmi

Wisdom & Compassion: The LUSON Journal

No abstract provided.


Where Pain Meets Grace, Callie Messick Nov 2025

Where Pain Meets Grace, Callie Messick

Wisdom & Compassion: The LUSON Journal

No abstract provided.


The Heart Of A Nurse, Mikayla Lang Nov 2025

The Heart Of A Nurse, Mikayla Lang

Wisdom & Compassion: The LUSON Journal

No abstract provided.


Resistance Is Not Futile: Plotting A Future Of Critical Thinking With Ai In Nursing Education, Alex Boggs Nov 2025

Resistance Is Not Futile: Plotting A Future Of Critical Thinking With Ai In Nursing Education, Alex Boggs

Wisdom & Compassion: The LUSON Journal

No abstract provided.


Nurse Faculty Burnout: A Narrative Literature Review, Susan Braud, Cynthia Goodrich, Amanda Martin Nov 2025

Nurse Faculty Burnout: A Narrative Literature Review, Susan Braud, Cynthia Goodrich, Amanda Martin

Wisdom & Compassion: The LUSON Journal

Background: Nursing faculty burnout significantly impairs teaching effectiveness and contributes to high turnover rates, threatening the future nursing workforce and overall quality of patient care.

Purpose: This review explores the contributing factors, consequences, and potential interventions related to nurse faculty burnout—a key driver of faculty attrition.

Method: An integrative literature review guided by the Whittemore and Knafl (2005) framework was conducted using the Melynk’s Level of Evidence Scale applied to assess the strength and quality of selected studies.

Results: Burnout in nurse faculty is multifactorial, stemming from overwhelming workloads, insufficient institutional support, and persistent systemic challenges. If unaddressed, it leads …


What Methods Do Pre-Licensure Bsn Students At A Christian University Use To Improve Resilience: A Qualitative Case Study, Beth Kelley Nov 2025

What Methods Do Pre-Licensure Bsn Students At A Christian University Use To Improve Resilience: A Qualitative Case Study, Beth Kelley

Wisdom & Compassion: The LUSON Journal

The purpose of this mixed-methods single-case study was to explore methods that pre-licensure Bachelor of Science in Nursing (BSN) students at a Christian university used to improve their resilience. Lazarus and Folkman's Transactional Model of Stress and Coping (1984) was employed as a theoretical framework, and the study asked: What methods did pre-licensure Bachelor of Science in Nursing (BSN) students at a Christian university use to manage stress and improve resilience? A convenience sample of 91 students was obtained to complete the demographic questionnaire, the Brief Resilience Scale, and the Perceived Stress Scale. Of those students, 25 volunteered for interviews …


Advancing Holistic Nursing: Bridging The Gap In Spiritual Care, Rachel Joseph Nov 2025

Advancing Holistic Nursing: Bridging The Gap In Spiritual Care, Rachel Joseph

Wisdom & Compassion: The LUSON Journal

No abstract provided.


Empowered By The Almighty: A Journey Of Faith And Nursing, Diane Bridge Nov 2025

Empowered By The Almighty: A Journey Of Faith And Nursing, Diane Bridge

Wisdom & Compassion: The LUSON Journal

No abstract provided.


Volume 3, Issue 1 - Complete Issue Nov 2025

Volume 3, Issue 1 - Complete Issue

Wisdom & Compassion: The LUSON Journal

No abstract provided.


Vitamin D Deficiency And Cardiovascular Health Disparities In High-Melanin Populations: A Scoping Review, Jalen K. Luter, Silver R. Kaylor, Michael S. Boyer Nov 2025

Vitamin D Deficiency And Cardiovascular Health Disparities In High-Melanin Populations: A Scoping Review, Jalen K. Luter, Silver R. Kaylor, Michael S. Boyer

Doctoral Projects

Cardiovascular disease (CVD) remains a leading cause of mortality and disproportionately affect individuals with darker skin tones, partly due to vitamin D deficiency (Sabzmakan et al., 2014). This Doctor of Nursing Practice (DNP) project uses a scoping review methodology to examine the relationship between vitamin D deficiency and cardiovascular outcomes, with an emphasis on high-melanin populations. Guided by the Joanna Briggs Institute Framework, the review synthesizes existing evidence, identifies gaps in representation and biomarker use, and highlights social and biological contributors to disparity. Databases including PubMed, CINAHL, EMBASE, and Scopus were searched, and studies were screened using standardized inclusion criteria: …


The Impact Of Peer Mentorship In Certified Registered Nurse Anesthesia Programs: A Scoping Review, Karoline Gasque, Kelly Mcreynolds, Shelia Crump Nov 2025

The Impact Of Peer Mentorship In Certified Registered Nurse Anesthesia Programs: A Scoping Review, Karoline Gasque, Kelly Mcreynolds, Shelia Crump

Doctoral Projects

Abstract
Problem statement: Certified Registered Nurse Anesthetist (CRNA) programs are known for
their rigorous curriculum, which predisposes Student Registered Nurse Anesthetists (SRNAs) to
challenges such as mental health issues, stress, and isolation.
Purpose: Review the literature and assess gaps in the literature to determine if peer mentorship
programs benefit SRNAs’ well-being, promote support, reduce stress, and improve retention.
Method: Databases were searched using keywords and inclusion criteria. Studies were
considered if they discussed peer mentorship in students, healthcare professionals, or nursing.
Patterns and themes were assessed to derive conclusions from the literature available. The
Population, Concept, and Context framework was …


Cv: Eleftheria Karapas (Nursing), Eleftheria Karapas Nov 2025

Cv: Eleftheria Karapas (Nursing), Eleftheria Karapas

Nursing Department Faculty Curricula Vitae

No abstract provided.


Over Reliance On Antidepressant Medication In Long-Term Care Facilities: Rethinking Mental Health Approaches, Kaylene Elder Nov 2025

Over Reliance On Antidepressant Medication In Long-Term Care Facilities: Rethinking Mental Health Approaches, Kaylene Elder

Walden Dissertations and Doctoral Studies

Depression is a prevalent mental health condition among older adults in long-term care (LTC) facilities and is often managed primarily through antidepressant medications. While these medications can be effective, their overuse in elderly populations increases the risk of falls, sedation, cognitive decline, and adverse drug interactions. This project addresses the need for safer, evidence-based alternatives by promoting non-pharmacological interventions that support holistic well-being. The proposed approach integrates gratitude journaling, vitamin D testing to identify deficiencies, and vitamin D supplementation for residents experiencing mild to moderate depressive symptoms. Implementation is led by nursing staff and supported by the interdisciplinary care team, …


From Urban Models To Rural Realities: Adapting Hepatitis C (Hcv) Care For Underserved Communities, Caitlin A. Mccain Nov 2025

From Urban Models To Rural Realities: Adapting Hepatitis C (Hcv) Care For Underserved Communities, Caitlin A. Mccain

2025 Fall Honors Capstones Projects - Archive

This literature review examines how Hepatitis C (HCV) screening and care programs can better serve underserved populations, particularly Spanish-speaking rural communities in border states. The research supports the Hep C- Colonias Advancing & Restoring Esperanza (C.A.R.E) program’s mission by incorporating recent findings from 32 studies gathered through PubMed, Medline and Google Scholar. Hep C C.A.R.E expanded from the HepVISTA expansion project provides HCV screening, education, vaccination and linkage to care for uninsured patients at partner sites in Laredo and Maverick County. Results indicate that while HCV elimination is feasible, significant gaps persist among rural uninsured and minority populations. Effective strategies …


Intouch Week Of November 17, 2025, New York Medical College Nov 2025

Effect Of Workplace Diversity, Equity, And Inclusion Programs On Black Women Leaders At Nonprofit National Associations Of Regulatory Boards, Alba Gisel Ayala Nov 2025

Effect Of Workplace Diversity, Equity, And Inclusion Programs On Black Women Leaders At Nonprofit National Associations Of Regulatory Boards, Alba Gisel Ayala

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project addressed a critical knowledge gap among clinical staff regarding the application of Social Determinants of Health (SDOH) within a local health department. Although SDOH screening tools and the statewide NCCARE 360 referral system were in place, inconsistent use hindered integration into patient care and limited efforts to advance health equity. Guided by the Johns Hopkins Evidence-Based Practice model and the ADDIE instructional framework, an educational intervention was developed and implemented to enhance staff knowledge, confidence, and integration of SDOH principles into workflow. Thirty-five clinical staff members participated in pre- and post-intervention assessments. Data …


Citronellol Reduces Sepsis-Induced Renal Inflammation Via Ap-1/Nf-Κb/Tnf-Α Pathway, Huda Rashid Atiyah, Sarmed H. Kathem, Surya M. Nauli Nov 2025

Citronellol Reduces Sepsis-Induced Renal Inflammation Via Ap-1/Nf-Κb/Tnf-Α Pathway, Huda Rashid Atiyah, Sarmed H. Kathem, Surya M. Nauli

Pharmacy Faculty Articles and Research

Sepsis is characterized by the over-production of pro-inflammatory cytokines. Cecal ligation and puncture (CLP) is a well-accepted model for recreating sepsis-induced renal injury in mice. The current study investigates how citronellol, a naturally occurring substance with a variety of biological characteristics, can prevent acute kidney inflammation brought on by CLP. In the CLP mouse model, citronellol was administered orally at doses of 50 and 100 mg/kg. Serum levels of creatinine and urea were used as markers of renal function, and the Murine Sepsis Score (MSS) was used to assess the severity of sepsis. According to our findings, CLP caused a …


Quality Improvement Project: Improving Competency Of Behavioral Health Technicians In Vital Sign Technique, Ashley Buescher Nov 2025

Quality Improvement Project: Improving Competency Of Behavioral Health Technicians In Vital Sign Technique, Ashley Buescher

Doctor of Nursing Practice Projects

Untreated hypertension or hypotension can lead to serious health problems, including death. Proper technique is essential when obtaining a blood pressure reading to improve patient safety. The goal of the quality improvement project was to improve competency in blood pressure technique by implementing standardized training. The initiative addressed discrepancies in blood pressure readings in the intake unit of a behavioral health hospital. Using the Stetler Model of Evidence-Based Practice and John Kotter’s 8-Step Change Model, a single sample, pre-post design was implemented over 4 weeks. The American Heart Association's blood pressure guidelines and the Teach-Back Observation Tool were used in …


Exploring Psychological Empowerment Among Hiv Support Groups, Harit Agroia, Leyla Mousli, Rock Braithwaite, Silvia Boron, Rene Padilla Nov 2025

Exploring Psychological Empowerment Among Hiv Support Groups, Harit Agroia, Leyla Mousli, Rock Braithwaite, Silvia Boron, Rene Padilla

Journal of Social, Behavioral, and Health Sciences

Support groups can provide members with space to discuss life issues, foster a sense of community, and promote connections with others. For people living with HIV, support groups can improve knowledge and awareness of tools and resources for HIV management, reduce stigma, improve social competence, and overall health. Studies that have connected empowerment and support group structures in populations with HIV have found promising results; however, a dearth of research demonstrates how applying theoretical frameworks can improve understanding of factors that increase empowerment among support group participants. The purpose of this phenomenological study was to apply the Psychological Empowerment Theory …


Staff Education To Improve Clinical Staff Knowledge Of The Social Determinants Of Health In A Public Health Setting, Alba Gisel Ayala Nov 2025

Staff Education To Improve Clinical Staff Knowledge Of The Social Determinants Of Health In A Public Health Setting, Alba Gisel Ayala

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project addressed a critical knowledge gap among clinical staff regarding the application of Social Determinants of Health (SDOH) within a local health department. Although SDOH screening tools and the statewide NCCARE 360 referral system were in place, inconsistent use hindered integration into patient care and limited efforts to advance health equity. Guided by the Johns Hopkins Evidence-Based Practice model and the ADDIE instructional framework, an educational intervention was developed and implemented to enhance staff knowledge, confidence, and integration of SDOH principles into workflow. Thirty-five clinical staff members participated in pre- and post-intervention assessments. Data …


Introducing Neuro Sscial Work: A Brief Reflection On Neuroscience And The Profession, Priscila Llamosa Nov 2025

Introducing Neuro Sscial Work: A Brief Reflection On Neuroscience And The Profession, Priscila Llamosa

Social Work Faculty Publications

This reflection introduces and contextualizes the term Neuro Social Work, which I coin to name a specialized practice area at the intersection of social work, neuroscience, and neurodiversity. Drawing on my experience as a social work educator and practitioner, I discuss social work’s uneasy relationship with neuroscience, marked both by the opportunity to deepen our understanding of trauma, development, and healing, and by the risks of using brain‑based evidence to individualize structural harms or justify surveillance of marginalized communities. I outline, in broad strokes, what distinguishes Neuro Social Work from general neuroscience‑informed practice. The note is intended as a concept …


Educating Staff On Hourly Rounding Toward Fall Prevention In A Long-Term Care Facility, Princess Aminata Kanu Nov 2025

Educating Staff On Hourly Rounding Toward Fall Prevention In A Long-Term Care Facility, Princess Aminata Kanu

Walden Dissertations and Doctoral Studies

The identified problem at the project site facility was rising incidences of patient falls, which was attributed to insufficient staff knowledge of evidence-based strategies for preventing falls, including purposeful hourly rounding (PHR). Research has demonstrated that PHR effectively reduces the risk of falls among patients by allowing clinicians to proactively address patient needs. The purpose of this staff education project was to enhance healthcare providers’ knowledge of PHR and its role in fall prevention. The practice-focused question that guided this project was: For staff in a long-term care facility, will training on hourly rounding increase knowledge toward the goal of …


Use Of Calcium Modification In Percutaneous Coronary Intervention: A Comprehensive Review, Noyan Ramazani, Ala W. Abdallah, Michael V. Dicaro, Divyansh Sharma, Aditi Singh, Kachon Lei Nov 2025

Use Of Calcium Modification In Percutaneous Coronary Intervention: A Comprehensive Review, Noyan Ramazani, Ala W. Abdallah, Michael V. Dicaro, Divyansh Sharma, Aditi Singh, Kachon Lei

Department of Internal Medicine Faculty Research

Calcified coronary lesions remain a challenge in percutaneous coronary intervention (PCI) in both situations of acute myocardial infarction (MI) and stable coronary syndrome. It significantly increases the risk of procedural complications due to difficulty in equipment delivery, balloon expansion, and stent delivery. Furthermore, stent thrombosis, dissection, perforation, and future in-stent restenosis occur more frequently in calcified coronary lesions, impacting repeat target vessel revascularization and increasing the risk of future MI. With intracoronary imaging (intravascular ultrasound and optical coherence tomography), peri-procedural success for treating calcified lesions has increased significantly. Different modalities of calcium modification techniques have since been introduced. This review …


From Nicu To Neighborhood: Supporting Premature Patients Beyond The Hospital, Bob Underwood, Jermine Harriet Romald Nov 2025

From Nicu To Neighborhood: Supporting Premature Patients Beyond The Hospital, Bob Underwood, Jermine Harriet Romald

Pediatrics in Practice: A CME Podcast

In this episode, we chat with neonatologist Harriet Romald, MD, FAAP, to explore the critical role pediatricians play in the long-term care of premature infants. From NICU discharge to developmental milestones, we discuss how pediatricians and neonatologists collaborate to ensure continuity of care, monitor common health challenges and navigate social determinants that impact outcomes. Whether you're new to caring for former NICU patients or looking to deepen your understanding, this conversation offers practical insights and the latest updates in neonatal follow-up care.

Click here to stream the podcast episode.