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Articles 15061 - 15090 of 24914
Full-Text Articles in Medicine and Health Sciences
Point Of Care Ultrasound To Manage Fluid Resuscitation In Septic Shock, Micah Vander Wiel, Ian Wiersma, Jaclyn Freese
Point Of Care Ultrasound To Manage Fluid Resuscitation In Septic Shock, Micah Vander Wiel, Ian Wiersma, Jaclyn Freese
Celebration of Research
Sepsis is a health complication causing immune dysregulation and ultimately end-organ damage, with millions of cases and deaths reported annually.1,2 The financial burden of sepsis is substantial and results in hospitalization costs in the United States exceeding $52 billion per year.3 Early diagnosis and effective management strategies are necessary to reduce morbidity and mortality following sepsis and septic shock.
This paper examines the use of Point-of-Care Ultrasound (POCUS), specifically Inferior Vena Cava (IVC) collapsibility and how it may be able to guide fluid resuscitation management for patients with sepsis.4 While POCUS has not consistently demonstrated a significant decrease in rates …
Assessing The Gaps Between Ethnic Populations: A Comparison Of Lipid-Lowering Interventions , Chasen Hershman, Gavin Lamott, Chester Dejong Md
Assessing The Gaps Between Ethnic Populations: A Comparison Of Lipid-Lowering Interventions , Chasen Hershman, Gavin Lamott, Chester Dejong Md
Celebration of Research
Pharmacological and lifestyle interventions have been a proven strategy for lowering the cardiovascular risk in all populations. Despite this, certain ethnic populations have a greater ASCVD risk due to either high LDL levels or other factors. The goal of this review is to analyze variables (specifically LDL) that contribute to certain ethnic populations demonstrating a greater risk of CVD as well as interventions that can improve outcomes. Treatment of hyperlipidemia requires a multifactorial approach which is tailored to the individual patients’ needs. Statins continue to be first-line pharmacological therapy for the treatment of lowering LDL. When combining a healthy diet …
Mobile Health Interventions In Diabetic Care In Times Of Environmental Crisis, Sarah Weisbrod, Makenzie Snyder, Maren Nerem, Katrina Hopkins, Pam Hulstein
Mobile Health Interventions In Diabetic Care In Times Of Environmental Crisis, Sarah Weisbrod, Makenzie Snyder, Maren Nerem, Katrina Hopkins, Pam Hulstein
Celebration of Research
A literature review was conducted between the months of August 2024 - November 2024 to explore the impact that the environmental effects of flooding have on those with diabetes mellitus (DM) and how the implementation of multiple forms of mobile health (mHealth) can aid in recovery and preparedness. Ten articles focusing on the various impacts that flooding and other natural disasters have on diabetic individuals, as well as the positive health outcomes tied to mobile applications and SMS messaging systems were reviewed. The purpose of this review was to examine current research regarding the treatment, education, and preparedness of diabetic …
Utilizing Buprenorphine In Patients With Opioid Use Disorder, Emma Roush, Dani Prusha, Emily Smith, Jaclyn Freese
Utilizing Buprenorphine In Patients With Opioid Use Disorder, Emma Roush, Dani Prusha, Emily Smith, Jaclyn Freese
Celebration of Research
Buprenorphine, a partial mu-opioid agonist, is a critical medication in treating opioid use disorder (OUD) and chronic pain. It was initially developed in the 1960s, then approved for pain management in the 1980s. However, over the past two decades, buprenorphine’s use has expanded to OUD treatment, demonstrating improved patient outcomes, enhanced treatment retention, and reduced opioid use. Its longer half-life allows for less frequent dosing and greater adherence compared to full agonists. Buprenorphine also has a more favorable safety profile compared to methadone, which results in lower risks of respiratory depression and overdose.
Despite its efficacy, buprenorphine remains underused due …
Subcutaneous Infusions For Hydration And Nutrition, Bryn Hoekman, Kelsie Dulmes, Laci Van Hauen, Megan Vankalsbeek, Mikayla Johnson, Pam Hulstein
Subcutaneous Infusions For Hydration And Nutrition, Bryn Hoekman, Kelsie Dulmes, Laci Van Hauen, Megan Vankalsbeek, Mikayla Johnson, Pam Hulstein
Celebration of Research
Subcutaneous (SC) infusions deliver fluids or medications into the body's fatty tissue using small needles. They are cost-effective, easy to use, comfortable, and carry a low risk of serious complications like infections. In hospital settings, IV access can be challenging, and oral fluid intake may be insufficient for proper hydration. Spencer Hospital was interested in the potential benefits of SC infusions and what population would benefit most. The purpose of this project was to examine SC infusions as an alternative for hydration when IV access is unavailable, focusing on pediatric, geriatric, and palliative population. It compared Hydration, nutrition status, and …
Factors Influencing Emergency Department Length Of Stay In Pediatric Burn Patients, Nishant S. Kumar Bs, Katherine Oag Msn, Rn, Accns-P, Ccrn, Lisa Vitale Bsn, Rn, Cpn, Tcrn, Mariah Malaniak Msn, Rn, Cpn, Cbrn, Justin Klein Md, Elika Ridelman Phd, Christina Shanti Md
Factors Influencing Emergency Department Length Of Stay In Pediatric Burn Patients, Nishant S. Kumar Bs, Katherine Oag Msn, Rn, Accns-P, Ccrn, Lisa Vitale Bsn, Rn, Cpn, Tcrn, Mariah Malaniak Msn, Rn, Cpn, Cbrn, Justin Klein Md, Elika Ridelman Phd, Christina Shanti Md
Medical Student Research Symposium
Introduction: Globally, the demand for pediatric emergency department (ED) visits has increased, leading to extended lengths of stay (LOS) in the ED. Prolonged ED length of stay (LOS) can delay definitive care and impact outcomes. This study investigates factors contributing to extended ED LOS in an urban, ABA-verified pediatric burn center.
Methods: We conducted a retrospective chart review of pediatric burn patients who presented between March 1, 2023, and March 1, 2024, with ED stays of ≥4 hours. Data on demographics, clinical presentation, and treatment were analyzed.
Results: Among 300 patients, the average ED LOS was 6 hours and 12 …
Determining The Wound Closure Capabilities Of A Biological Engineered Blood Vessel For Hd Access, Brianna Regan, Alex Dumitru, Mai Lam
Determining The Wound Closure Capabilities Of A Biological Engineered Blood Vessel For Hd Access, Brianna Regan, Alex Dumitru, Mai Lam
Medical Student Research Symposium
End stage renal disease (ESRD) is a prominent chronic condition with dialysis as a primary treatment option. Dialysis necessitates implementation of an access point, with the gold standard being an AV fistula which possesses multiple shortcomings. Alternative access points, namely synthetic grafts, do not allow wound healing characteristics. This work aims to explore how a tissue engineered vascular graft (TEVG) may be able to address these issues by allowing a long-term access point for HD that can close puncture wounds.
The effects of growth factors on our cells were tested preliminarily by means of a scratch assay on plates of …
Safety And Efficacy Of 112 Mg Intranasal Esketamine In Patients With Treatment-Resistant Depression: A Retrospective Observational Study From Outpatient Community Clinics, Kirsten Brinkmeier, Michael Kritzer, Brandon Doan, Cecilia Li, Nicholas Mischel
Safety And Efficacy Of 112 Mg Intranasal Esketamine In Patients With Treatment-Resistant Depression: A Retrospective Observational Study From Outpatient Community Clinics, Kirsten Brinkmeier, Michael Kritzer, Brandon Doan, Cecilia Li, Nicholas Mischel
Medical Student Research Symposium
This retrospective study examined the safety and efficacy of 56, 84, and 112 mg intranasal (IN) esketamine via medical record review of 24 patients with treatment resistant depression (TRD). Doses ranged from 56 mg to 112 mg and were titrated across sessions to maximize individual response while considering tolerability. Treatment response was defined by reduction in average Patient Health Questionnaire-9 (PHQ-9) scores. Tolerability was defined by blood pressures at baseline, 40 minutes after, and 2 hours after drug administration. Patients ranged from 19 to 60 years old (average 38.87), and 15 (62.5%) were female. Patients received an average of 1 …
Evaluating Engagement In Health Care And Substance Use Disorder Services Among People Who Use Drugs, Tiffany Mckenney, Kevin Cobty, Divya Boorle, Julie Gleason-Comstock
Evaluating Engagement In Health Care And Substance Use Disorder Services Among People Who Use Drugs, Tiffany Mckenney, Kevin Cobty, Divya Boorle, Julie Gleason-Comstock
Medical Student Research Symposium
An urban community-based organization conducted a study to examine demographics of individuals who use drugs and their approaches to risk reduction. A substantial proportion reported encountering significant barriers to accessing substance use disorder (SUD) services.
In collaboration with a state survey, the community organization recruited a convenience sample of individuals who actively used drugs, examining substance use patterns, healthcare access, and barriers to SUD services. Community health workers facilitated outreach efforts, focusing on harm reduction engagement, and healthcare access.
Data were collected from 55 individuals. 51% identified as male, 48% as female, and 2% as LGBTQIA+. 67% identified as White/Caucasian, …
The Effect Of Abdominal Insufflation On Transversus Abdominis Plane (Tap) Block Efficacy In Laparoscopic Gynecologic Surgery, Hussein A. Bazzi, Justin Hruska M.D., Christopher Kliethermes M.D., Anne Thomas, Wael Saasouh M.D.
The Effect Of Abdominal Insufflation On Transversus Abdominis Plane (Tap) Block Efficacy In Laparoscopic Gynecologic Surgery, Hussein A. Bazzi, Justin Hruska M.D., Christopher Kliethermes M.D., Anne Thomas, Wael Saasouh M.D.
Medical Student Research Symposium
Introduction:
Approximately 15 million laparoscopic procedures are performed annually worldwide, with 4.8 million (32%) occurring in the United States. Laparoscopy is widely used for procedures such as bilateral tubal sterilizations, hysterectomies, and treatments for endometriosis and adhesions. During gynecologic laparoscopic surgeries, the abdomen is inflated with pressurized carbon dioxide for surgical visualization. Pain management typically involves a transversus abdominis plane (TAP) block, which provides intermediate postoperative pain relief (lasting 12–24 hours). This study evaluates the efficacy of TAP blocks performed during insufflation to improve postoperative pain outcomes compared to the traditional technique.
Methods:
This patient-blinded study included female gynecologic patients …
Measures Of Digital Health Literacy: A Scoping Review, Jessica Elderkin, Eliza Beal, Leva Gorji
Measures Of Digital Health Literacy: A Scoping Review, Jessica Elderkin, Eliza Beal, Leva Gorji
Medical Student Research Symposium
Title: Measures of Digital Health Literacy: A Scoping Review
Authors: Leva Gorji, DO; Jessica Elderkin, BA; Eliza W. Beal, MD
Background: In the evolving field of medicine, electronic information and communication technologies have become profound tools for combating obstacles related to geographic barriers. As such, understanding and improving digital health literacy (DHL) is imperative to ensure that this form of healthcare is appropriately accessible to users. The objective of this scoping review is to gauge the tools available for assessing DHL.
Methods: A scoping review was conducted following the preferred reporting items for systematic review and meta-analyses (PRISMA) guidelines. In …
Investigating The Effects Of Intranasal Esketamine On Suicidal Ideation In Patients With Treatment-Resistant Depression, Ciara White, Izma N. Khaliq, Nicholas Mischel, Kirsten Brinkmeier
Investigating The Effects Of Intranasal Esketamine On Suicidal Ideation In Patients With Treatment-Resistant Depression, Ciara White, Izma N. Khaliq, Nicholas Mischel, Kirsten Brinkmeier
Medical Student Research Symposium
Treatment-resistant depression (TRD) remains a significant challenge, with many patients failing conventional treatments. While intranasal esketamine has demonstrated efficacy for depression, its specific effects on suicidal ideation (SI)—a critical symptom of depression—are underexplored. Unlike most studies that adhere to the 84mg dosing paradigm administered twice weekly, this study explores the novel use of varying esketamine doses, including 54mg, 84mg, and 112mg. This study aims to evaluate the impact of varying esketamine doses (54mg, 84mg, and 112mg) on SI in a real-world outpatient population (n=24). This study analyzed data from patients in Southwest Michigan with major depressive disorder (MDD) and psychiatric …
Efficacy Of First Aid Training In The Curriculum Of First Year Medical Students, Timothy Chalom, Sophia L. Braun, Laura Elizabeth Sansoterra, Kevin Chau, Zaid Y. Saadeh, Parmida Abdoli, Charles Hughes, Kristiana Kaufmann
Efficacy Of First Aid Training In The Curriculum Of First Year Medical Students, Timothy Chalom, Sophia L. Braun, Laura Elizabeth Sansoterra, Kevin Chau, Zaid Y. Saadeh, Parmida Abdoli, Charles Hughes, Kristiana Kaufmann
Medical Student Research Symposium
Background
First Aid First (FAF) provides free and accessible first aid training to members of the Detroit community, including first-year medical students, to empower individuals to respond quickly properly, and confidently during real life emergencies.
Methods
First aid training sessions last 1.5 hours, and are taught by Wayne State University School of Medicine (WSUSOM) medical students and physicians. FAF trains incoming WSUSOM medical students on CPR, Stop the Bleed, and many more skills. Didactic instruction and hands-on demonstration allows participants to practice skills under the guidance of trained instructors. A pre-/post 20-question quiz on emergency responses and any prior first …
Complications Of Breast Reconstruction: Does The Area Deprivation Index Predict Risk?, Andrew Hannoudi, Noah M. Atisha, Amolak S. Jhand, Kinan Sawar, Dunya M. Atisha
Complications Of Breast Reconstruction: Does The Area Deprivation Index Predict Risk?, Andrew Hannoudi, Noah M. Atisha, Amolak S. Jhand, Kinan Sawar, Dunya M. Atisha
Medical Student Research Symposium
INTRODUCTION: Despite mandated post-mastectomy reconstruction coverage since the Women’s Health and Cancer Rights Act (1998), vulnerable populations may be prone to breast reconstruction complications. The Area Deprivation Index (ADI) reflects neighborhood socioeconomic status utilizing US census data. This study investigates ADI's relationship to breast reconstruction complications.
METHODS: A retrospective study of immediate pre-pectoral direct-to-implant reconstruction patients at a metropolitan healthcare system from 2018-2022 was conducted. Patients were stratified by ADI: <50th percentile (ADI=1-5) and ≥50th percentile (ADI=6-10). Demographics, medical history, treatment history, and postoperative outcomes were compared. Descriptive statistics identified differences between ADI groups. Minor complications were defined as incidence of hematoma, seroma, superficial wounds, full thickness necrosis, or oral antibiotic-treated cellulitis. Major complications were defined as incidence of hospital readmission or return to OR. Long-term complications were defined as incidence of capsular contracture or ≥3 revisions. Logistic regression assessed ADI’s predictive value, accounting for confounds between cohorts.
RESULTS: Of 195 patients, 147 had low ADI and 48 had high ADI. Significant differences in BMI and race were found between groups. Low ADI demonstrated higher …50th>
A New Paradigm For Looking At Infertility: A Pilot Study From Metropolitan Detroit, Indrea Joplin, Tonia Jones, Melanie Hanna-Johnson, Md, Anil N. F Aranha
A New Paradigm For Looking At Infertility: A Pilot Study From Metropolitan Detroit, Indrea Joplin, Tonia Jones, Melanie Hanna-Johnson, Md, Anil N. F Aranha
Medical Student Research Symposium
No abstract provided.
Clinical Characteristics And Outcomes Of Pediatric Staphylococcal Scalded Skin Syndrome (Ssss) At An Inner-City Tertiary Care Center, Nina Kb Gust Md, Ashley Frei Bs, Rebecca M. Adams Bs, Elika Ridelman Phd, Christina Shanti Md, Ronald Thomas Phd, Jocelyn Y. Ang Md
Clinical Characteristics And Outcomes Of Pediatric Staphylococcal Scalded Skin Syndrome (Ssss) At An Inner-City Tertiary Care Center, Nina Kb Gust Md, Ashley Frei Bs, Rebecca M. Adams Bs, Elika Ridelman Phd, Christina Shanti Md, Ronald Thomas Phd, Jocelyn Y. Ang Md
Medical Student Research Symposium
Introduction
Staphylococcal Scalded Skin Syndrome (SSSS) is a blistering skin condition caused by a toxin-producing staphylococcus species. Epidemiologic studies on pediatric SSSS in the United States are limited, with a reported incidence of 7.67 cases per million children and 45.1 per million infants. Immature renal function, lack of protective antibodies, and increased exotoxin target desmoglein-1 are hypothesized to increase incidence in younger children. We aimed to determine clinical and microbiological characteristics of pediatric SSSS and factors that could help predict disease severity.
Methods
A retrospective chart review was performed for admitted patients under 18 years old diagnosed with SSSS from …
Socioeconomic Disparities And Challenges In Urban Detroit: Predicting Loss To Follow-Up After Treatment For Intracranial Aneurysms, Hailey Yasmine Rizk, Noah Goldberger, Jared Reese, Pouya Entezami
Socioeconomic Disparities And Challenges In Urban Detroit: Predicting Loss To Follow-Up After Treatment For Intracranial Aneurysms, Hailey Yasmine Rizk, Noah Goldberger, Jared Reese, Pouya Entezami
Medical Student Research Symposium
Intracranial aneurysmal subarachnoid hemorrhages (aSAH) can cause debilitating acute and chronic symptoms, and loss-to-follow-up (LTF) is a prominent issue affecting longitudinal care. Higher rates of follow-up have been correlated with better outcomes, and this study sought to identify disparities in the urban Detroit patient population and factors that may predispose patients to not receiving post-hospitalization care.
This retrospective study identified 352 patients with ruptured aSAH from 2013-2024 treated within a metro-Detroit hospital system. LTF was defined as lack of follow-up imaging >500 days post-discharge. Patient demographics and socioeconomic variables were reviewed, and Chi-square and Fisher’s tests were utilized to determine …
Effects Of Induced Arousal On Subsequent Apnea And Hyperpnea In Central Sleep Apnea, Ahmed Jafri, Safwan Badr, Abdulghani Sankari, Ahmad Aldwaikat, Nishtha Pandya
Effects Of Induced Arousal On Subsequent Apnea And Hyperpnea In Central Sleep Apnea, Ahmed Jafri, Safwan Badr, Abdulghani Sankari, Ahmad Aldwaikat, Nishtha Pandya
Medical Student Research Symposium
Central sleep apnea (CSA) is characterized by recurrent cycles of apnea/hypopnea alternating with hyperpnea. Brief arousals following apnea/hypopnea are postulated to perpetuate CSA via hypocapnia below the apneic threshold.
We hypothesized that apnea or hypopnea would follow hyperventilation due to induced-respiratory arousals. Participants diagnosed with mild to severe sleep-disordered breathing (AHI: 10-64 events per hour) were enrolled. We studied 5 patients with CSA who were otherwise healthy (4 male, 1 female, age: 62-72 years, BMI: 25.6-37.2 kg/m2) During overnight polysomnography (PSG), participants were initially stabilized with PAP therapy set to the pressure level required to maintain airway patency …
Socioeconomic And Demographic Factors In Genetic Testing Utilization Among Advanced Prostate Cancer Patients: A Retrospective Single-Institution Study, Alexandra T. Skowron Ms, Karen Childers, Courtney M. Rose Ms, Kyle C. Mcelyea Md, Avery K. Supernois Bs, Yousuf Hussain, Mohammed Baseer Ms, Sunita Ghosh Phd, Clara Hwang Md
Socioeconomic And Demographic Factors In Genetic Testing Utilization Among Advanced Prostate Cancer Patients: A Retrospective Single-Institution Study, Alexandra T. Skowron Ms, Karen Childers, Courtney M. Rose Ms, Kyle C. Mcelyea Md, Avery K. Supernois Bs, Yousuf Hussain, Mohammed Baseer Ms, Sunita Ghosh Phd, Clara Hwang Md
Medical Student Research Symposium
Introduction
Germline genetic testing in patients with advanced prostate cancer (PCa) is underutilized. Socioeconomic and demographic factors are hypothesized to affect low rates of testing, but causality has not been established. This single institution, retrospective study aimed to understand what barriers may affect germline genetic testing for PCa patients.
Methods
The Henry Ford Health (HFH) tumor registry was queried for new diagnoses of stage 3, 4A and 4B PCa from 2017-2022. Census tract levels were assigned using patient addresses and neighborhood-based geocoding was completed for Median household income (gMHI) and Social vulnerability index (SVI). gMHI and SVI were divided into …
Bmi, Opioid Use, And Pain Perception: Insights From The Dipa Scale In Orthopedic Patients, Alqasim Elnaggar B.A., Haytham Alqasmi B.S., Ahmad Almaat B.S., Omar Abdalla B.S., Nimr Assaf B.S., Richard Tuttle B.S., Rahul Vaidya M.D.
Bmi, Opioid Use, And Pain Perception: Insights From The Dipa Scale In Orthopedic Patients, Alqasim Elnaggar B.A., Haytham Alqasmi B.S., Ahmad Almaat B.S., Omar Abdalla B.S., Nimr Assaf B.S., Richard Tuttle B.S., Rahul Vaidya M.D.
Medical Student Research Symposium
Introduction
Body Mass Index (BMI) and Morphine Milligram Equivalents (MMEs) are critical factors in pain management, especially for patients undergoing orthopedic procedures such as joint replacement and spinal surgeries. The Detroit Interventional Pain Assessment (DIPA) scale is a novel tool for stratifying pain severity to optimize pain management strategies. This study evaluates the relationship between BMI, MME levels, and pain ratings using this scale, to inform tailored analgesic strategies for orthopedic patients.
Methods
527 patients undergoing joint replacement or spinal procedures were included in this retrospective analysis. Patients were categorized by BMI (<30 or ≥30) and MME levels (0, 1–20, 21–49 MME). Pain ratings (no pain, tolerable, intolerable) were assessed using the DIPA scale. Chi-squared tests were used to evaluate associations between BMI and MME levels for each pain rating category. Sample sizes varied across groups, with higher MME categories limited by smaller sample sizes. Statistical significance was determined at p<0.05.
Results
For MME=0, a significant association was …
30>Variation In Treatment Recommendations For Low-Risk Prostate Cancer: A Focus On Active Surveillance Across Physician Specialties, Sinyu Yang B.S., Tiffany Chu B.S., Cathryn Bock Ph.D, Jinping Xu M.D.
Variation In Treatment Recommendations For Low-Risk Prostate Cancer: A Focus On Active Surveillance Across Physician Specialties, Sinyu Yang B.S., Tiffany Chu B.S., Cathryn Bock Ph.D, Jinping Xu M.D.
Medical Student Research Symposium
Prostate cancer (PC) is the second leading cause of cancer-related death in men globally, with 1 in 8 men in the US diagnosed during their lifetime. For Low-Risk Prostate Cancer (LRPC), management options include Watchful Waiting (WW), Active Surveillance (AS), or curative treatments such as prostatectomy or radiation. While curative treatments can have significant long-term side effects like urinary incontinence and sexual dysfunction, AS is less invasive and preferred due to fewer adverse effects. However, variations in physician training may lead to differing recommendations, potentially causing confusion or frustration for patients consulting multiple specialists. This study investigates whether treatment recommendations—AS, …
Externalizing Behavior Problems And Attentional Domains In A Community-Based Adolescent Sample, Kamakashi Sharma
Externalizing Behavior Problems And Attentional Domains In A Community-Based Adolescent Sample, Kamakashi Sharma
Medical Student Research Symposium
Externalizing behavior problems are characterized by maladaptive behavioral patterns directed toward the external environment, such as poor impulse control, aggression, and inattention. While existing literature suggests that attention may play a critical role in the cognitive profile of externalizing behaviors, the relationship between externalizing problem behaviors and specific attention domains in school-age youth remains understudied. This gap is particularly important as externalizing problems are prevalent during this developmental period and are predictive of adverse outcomes. In this study, we examined the association between externalizing problem behaviors and attentional performance in a community sample of 69 adolescents (M + SD = …
Analysis Of Chromatin Accessibility Changes In Endothelial Cells Exposed To Plastic Contaminants, Mikhail Y. Salnikov, Carly Boye, David B. Witonsky, Gabrielle Garlicki, Adnan Alazizi, Francesca Luca, Roger Pique-Regi
Analysis Of Chromatin Accessibility Changes In Endothelial Cells Exposed To Plastic Contaminants, Mikhail Y. Salnikov, Carly Boye, David B. Witonsky, Gabrielle Garlicki, Adnan Alazizi, Francesca Luca, Roger Pique-Regi
Medical Student Research Symposium
Degradation products from everyday plastic products are known to bioaccumulate and have also been shown to contaminate drinking water and food sources. BPA and phthalates are endocrine disrupting chemicals and plastic components that have previously been associated with endothelial cell dysfunction, atherosclerotic and other adverse cardiovascular events. However, there is a limited understanding of the mechanisms underlying these associations, such as genome-wide chromatin accessibility changes in endothelial cells exposed to these compounds. The purpose of this study is to explore genome-wide changes in chromatin accessibility associated with plastic exposure, as well as the discovery of transcription factor binding motifs dysregulated …
Barriers To Substance Use Treatment In Pregnant Populations: A Literature Review And Patient Perspectives In Detroit, Noor Sulaiman, Ranya Krayem, Sarah Chamdin, Salam Sulaiman, Amy Loree Phd, Alyssa Vanderziel Phd, Julia Felton Phd
Barriers To Substance Use Treatment In Pregnant Populations: A Literature Review And Patient Perspectives In Detroit, Noor Sulaiman, Ranya Krayem, Sarah Chamdin, Salam Sulaiman, Amy Loree Phd, Alyssa Vanderziel Phd, Julia Felton Phd
Medical Student Research Symposium
Introduction:
Substance use during pregnancy is one of the leading preventable causes of pregnancy-associated mortality in Michigan, yet pregnant individuals who use substances are less likely to access prenatal care or substance use disorder (SUD) treatment relative to other pregnant people, leading to worse outcomes for the parent and fetus. Understanding the barriers to treatment that pregnant people with SUD face is essential to improving health outcomes and access to care. The aim of this project is to identify accessibility barriers to substance use treatment in pregnant populations through a literature review and key informant interviews with individuals who misused …
The Impact Of Legislation And Implementation Of An Emergency Department Medications For Opioid Use Disorder Program On Buprenorphine Administration, Jacob Manteuffel, Joseph Miller, Nadine Jawad, Alexis Maroney, Revelle Gappy, Nora Sharba, Grant Zydeck
The Impact Of Legislation And Implementation Of An Emergency Department Medications For Opioid Use Disorder Program On Buprenorphine Administration, Jacob Manteuffel, Joseph Miller, Nadine Jawad, Alexis Maroney, Revelle Gappy, Nora Sharba, Grant Zydeck
Medical Student Research Symposium
The emergency department (ED) plays a critical role in addressing a wide range of healthcare needs and can be the first point of contact for individuals with opioid use disorder (OUD). Buprenorphine, a partial opioid agonist, is a medication that helps treat OUD. On January 12, 2023, federal changes removed a major barrier, allowing all clinicians to prescribe buprenorphine. Later in 2023, a Medications for Opioid Use Disorder (MOUD) program was implemented in a high-volume free-standing ED. We aimed to review the impact of these changes on buprenorphine administration.
We conducted a retrospective chart review of buprenorphine administration and ICD …
Evaluating The Current State Of Quality Measure Reporting In The Merit-Based Incentive Payment System, Kinan Sawar, Geoffrey Potts Md
Evaluating The Current State Of Quality Measure Reporting In The Merit-Based Incentive Payment System, Kinan Sawar, Geoffrey Potts Md
Medical Student Research Symposium
The Merit-Based Incentive Payment System (MIPS) requires physicians to report quality measures along with other metrics that are used to determine an annual percentage adjustment to physician Medicare Part B payments. Unfortunately, physicians have been forced to choose from an ineffective, limited set of quality measures. This has led to an overreliance on process measures, which fail to stratify physician performance effectively; it has also led to differences in the number of reporting options across specialties, resulting in unequal opportunity for physicians to succeed in MIPS. Using Centers for Medicare and Medicaid Services (CMS) public use file data from 2021-2024, …
Clinical And Imaging Correlates Of Cognitive Impairment Patterns In Early Unilateral Brain Injury Associated With Sturge-Weber Syndrome, Halah Keramane, Csaba Juhasz Md, Phd, Michael E. Behen Phd, Aimee Luat Md
Clinical And Imaging Correlates Of Cognitive Impairment Patterns In Early Unilateral Brain Injury Associated With Sturge-Weber Syndrome, Halah Keramane, Csaba Juhasz Md, Phd, Michael E. Behen Phd, Aimee Luat Md
Medical Student Research Symposium
Background: Sturge-Weber syndrome (SWS) is a rare neurocutaneous disease characterized by cerebral venous malformations leading to early damage of affected brain regions. Clinical symptoms include seizures, motor and cognitive impairment. Most SWS patients have unilateral brain involvement, and previous studies reveal substantial neurological plasticity in some of them. Some children with left-hemispheric damage demonstrate, paradoxically, preserved verbal functions and reduced nonverbal functions (a “crowding” effect), suggesting contralateral functional reorganization from damaged cortical regions. We evaluated the incidence as well as clinical and imaging correlates of such functional reorganization/crowding.
Methods: Forty-six patients (age: 2.5-24 years) with unilateral SWS underwent neurocognitive evaluations …
Intranasal Delivery Of Human Olfactory Stem Cells In Sci Treatment, Muhammad Dawood Tarar, Alexander Hayes, Camera Dockery, Alexander Weiss, Marwa Elgirsg, Medha Guduguntla, Jean Peduzzi-Nelson
Intranasal Delivery Of Human Olfactory Stem Cells In Sci Treatment, Muhammad Dawood Tarar, Alexander Hayes, Camera Dockery, Alexander Weiss, Marwa Elgirsg, Medha Guduguntla, Jean Peduzzi-Nelson
Medical Student Research Symposium
Background:
Olfactory stem cells hold great promise as a treatment for neural injury and disease. Two types of stem cells are known to be present in the olfactory mucosa – basal epithelial cells and mesenchymal cells in the lamina propria. Basal epithelial cells, under stimulation of mesenchymal cells, are known to differentiate into neurons1,2. Among other immunomodulatory functions3, mesenchymal cells are also observed to differentiate into neurons. Improvement with olfactory stem cells is observed in various animal models, including head injury4, nerve repair5,6, and Alzheimer’s disease7. The purpose of this …
Evaluating Value Of Trigger Finger Release: Ambulatory Surgical Center Vs. Procedure Room, Katiya A. Barkho Bs, Richard Tuttle Bs, Lucas Kopp Bs, Mary Zylinski Bs, Charles Day Md, Mba
Evaluating Value Of Trigger Finger Release: Ambulatory Surgical Center Vs. Procedure Room, Katiya A. Barkho Bs, Richard Tuttle Bs, Lucas Kopp Bs, Mary Zylinski Bs, Charles Day Md, Mba
Medical Student Research Symposium
Introduction:
As healthcare costs rise, improving cost-efficiency is essential. This study evaluates the value of trigger finger release (TFR) surgery in ambulatory surgical centers (ASCs) and procedure rooms (PRs), hypothesizing that PRs offer higher value due to lower overhead costs.
Methods:
The cost of TFR was assessed according to Time-Driven Activity-Based Costing (TDABC) methodology. Expenses were categorized into four categories:
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Direct Labor: Personnel utilization costs
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Direct Fixed: Building and utility fees
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Direct Supply: Equipment costs
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Indirect: Maintenance, administration, and marketing
Changes in pre-operative and 3-month post-operative PROMIS Pain Interference (PI) and Upper Extremity (UE) scores were multiplied by average life-years …
Patient And Healthcare Provider Knowledge Of Exercise During Pregnancy., Robert J. Leone, Dr. Shihyun Kim, Vidhi Sharma, Monique Swain
Patient And Healthcare Provider Knowledge Of Exercise During Pregnancy., Robert J. Leone, Dr. Shihyun Kim, Vidhi Sharma, Monique Swain
Medical Student Research Symposium
Title: Patient and Healthcare Provider Knowledge of Exercise During Pregnancy.
Authors: Leone, R., Kim, S., Sharma, V., Swain, M.
Introduction:
Physical activity before and during pregnancy can significantly improve pregnancy outcomes. ACOG’s evidence-based recommendations help healthcare providers (HCPs) educate patients regarding the benefits of exercise during pregnancy. However, many patients do not engage in regular physical activity. We aim to determine how provider counseling on exercise per ACOG recommendations impacts patients’ exercise and perception of exercise during pregnancy.
Methods:
This is a survey study of HCPs offering prenatal and postpartum care, and pregnant patients. HCPs were given surveys …