Medicine and Health Sciences Commons^™

Efficacy Of Dietary Interventions For Irritable Bowel Syndrome: A Systematic Review And Network Meta-Analysis, Hossein Haghbin, Fariha Hasan, Manesh Kumar Gangwani, Nurruddinkhodja Zakirkhodjaev, Wade Lee-Smith, Azizullah Beran, Faisal Kamal, Benjamin Hart, Muhammad Aziz

Division of Gastroenterology and Hepatology Faculty Papers

Introduction: Irritable bowel syndrome (IBS) is a common condition that alters the quality of life of patients. A variety of dietary interventions have been introduced to address this debilitating condition. The low-FODMAP diet (LFD), gluten-free diet (GFD), and Mediterranean diet are examples showing efficacy. The aim of this network meta-analysis was to compare these interventions to find the best approach. Methods: We performed a systematic review of the available literature through 14 March 2024 in the following databases: Embase, PubMed, MEDLINE OVID, Web of Science, CINAHL Plus, and Cochrane Central. We only included randomized controlled trials (RCTs). We used a …

Impact Of Training For Nursing Staff In The Prevention Of Hapis, Onyinye E. Ohia, Colleen A. Anthony

Master's Projects

Abstract

Background: The incidence of Hospital acquired pressure injuries (HAPIs) have remained a problem in healthcare despite concerted efforts by hospitals and other governmental agencies to eliminate the problem via policy and emphasis on safety. There is support in literature for the training of healthcare professionals as an important tool in the prevention and management of HAPIs. Despite the existence of studies that link training of nurses to a reduction in rates of HAPIs, evidence in support of that is still piecemeal; with poorly defined outcomes.

Aims and objectives: The aim of this integrative review is to identify …

Senior Nursing Students' Perceptions Of Their Effectiveness In The Utilization Of De-Escalation Techniques: A Phenomenological Study, Chinelo N. Anadu

Doctoral Dissertations and Projects

This qualitative phenomenological study explored senior nursing students’ perceptions of their effectiveness in utilizing de-escalation techniques. The theories that guided this study were Bandura’s self-efficacy theory and Kolb’s experiential learning theory. Self-efficacy is one’s ability to organize, conduct, and successfully perform a task. Bandura’s self-efficacy theory focuses on individuals’ perception of their ability to perform a task, not the action’s result. Kolb’s theory emphasizes that learning is a process, and modifying experiences creates knowledge. The participants for this study were senior nursing students from two medium-sized universities in the mid-Atlantic region of the United States. A sample of 11 senior …

Evaluating Pharmacokinetic And Age-Related Parameters In The Static Mechanistic Model To Enhance The Accuracy Of Drug-Drug Interaction Prediction In The Geriatric Population, Jing Wang

Doctoral Dissertations and Projects

Drug-drug interactions (DDIs) can significantly impact drug efficacy, patient safety, and healthcare costs. While potentially life-threatening, DDIs are also predictable, manageable, and avoidable. Due to polypharmacy and age-related physiological changes, DDIs are most prevalent in the geriatric population. However, geriatric patients are often excluded from clinical trials for ethical and scientific reasons. DDI assessments in the geriatric population are typically replied on extrapolated from younger populations, which may not always be appropriate. This research investigates whether the computational model, particularly the static mechanistic model, can accurately and appropriately predict DDIs in the geriatric population by modifying pharmacokinetic and age-related parameters …

Wildlife Factors And Zoonotic Spillover In Sub-Saharan Africa, Bernard Mgba

Doctoral Dissertations and Projects

Zoonotic spillover, the transmission of infectious pathogens from animals to humans, is a critical public health concern in Sub-Saharan Africa. This study examines the role of wildlife factors in zoonotic spillover within this region, highlighting the complex interplay between human-wildlife interactions, environmental changes, and emerging zoonotic diseases. The research underscores that Sub-Saharan Africa is particularly vulnerable due to its rich biodiversity, cultural practices involving wildlife, and socioeconomic challenges. Factors such as habitat encroachment, wildlife consumption, and inadequate health infrastructure contribute to the heightened risk of zoonotic spillover. The study employs an online survey followed with a contextual analysis, and socioeconomic …

Development And Evaluation Of Nurse Practitioner- Driven Appointment Reminder Initiative At An Outpatient Mental Health Clinic, Adaku Ogoke

Doctoral Dissertations and Projects

No-shows or missed appointments have a negative impact on the effectiveness and efficiency of healthcare facilities. No-shows contribute to high healthcare costs and lost revenue due to underutilization of services, unnecessary disruptions in workflow, increased workload, and scheduling challenges. Mental health clinics report high no-show rates due to factors such as forgetfulness among patients. The purpose of this quality improvement project was to implement a text message patient appointment reminder system to reduce the no-show rate and increase provider knowledge in an outpatient mental health clinic in 15 weeks. The project was guided by the Iowa model of evidence-based practice …

The Effectiveness Of Education Utilizing A Digital Patient Education Platform For Nursing Staff Working In A Military Medical Treatment Facility, Meki Bocage

Doctoral Dissertations and Projects

Currently, the use of digital health technology has been found to improve patients’ experiences, health outcomes, and quality of care. Furthermore, the Defense Health Agency (DHA) is focused on leveraging cutting-edge technologies to optimize healthcare delivery and improve patient experiences. The purpose of this evidence-based practice process improvement project supports providing educational intervention to nursing staff through videoconferencing or lecture learning opportunities. The project focused on successfully educating nursing staff from at least three MTFs on the use of a patient education platform by the conclusion of the 30-day intervention through individual web-based pre and post questionnaires. Ultimately, 15 registered …

Injury Prevalence Among Females Playing American Football, Anthea Warren-Williams

Doctoral Dissertations and Projects

While extensive research has examined injuries in men's football, there is a significant lack of studies systematically investigating the types, patterns, and long-term effects of injuries among female football players. This study aimed to address this gap by investigating the types and frequencies of injuries sustained by female American football players. A recruitment letter was sent via email, and following approval, an anonymous online survey was distributed to collect data from participants about their injuries during the 2023 season. The study included 13 teams from the WFA Pro division, with a total of 647 players, recruiting 245 participants aged 19 …

Exploring Generational Differences Within The Nursing Profession: An Evidence-Based Practice Project, Danielle Sienkiewicz

Doctoral Dissertations and Projects

Nursing practice has evolved since its initial presentation. The 2020 pandemic played a significant role in changing nursing dynamics. Acute care nurses have become responsible for a plethora of tasks once a patient enters the doors of their facility. While education and skills training can be implemented, there are other aspects requiring greater attention. Generational differences have become more apparent in practice. Generational differences are only recently gaining attention and could use more focus in large organizations. The workforce has become a combination of Baby Boomers, Generation X, Millennials, and Generation Z. The Silent Generation, also referred to as Veteran …

Promoting Advance Care Planning In Primary Care: A Pilot Study On The Impact Of Clinician Education And Workflow Development, Lisa Nicole Turcotte

Doctoral Dissertations and Projects

Although evidence supports the efficacy of advance care planning (ACP) in improving quality of care and the overall well-being of patients and families, there are many barriers to engagement in this process. Fortunately, clinician and patient education and workflow development in primary care settings have shown promise in their ability to overcome these obstacles to improve awareness of and engagement with the ACP process as part of preventative care. The purpose of this project was to apply current research on this topic to improve patient engagement with ACP in the primary care setting using the Iowa Model of evidence-based practice. …

A Comparison Of Depression, Anxiety, And Stress Amongst Male And Female Clinical Laboratory Leaders, Elizabeth M. Payne

Doctoral Dissertations and Projects

This study examined the potential relationship between male and female emotional disparities -- specifically depression, anxiety, and stress -- in clinical laboratory leaders. The Depression, Anxiety, and Stress Scale-21 (DASS-21) was used to determine levels of depression, anxiety, and stress in 16 male and 16 female clinical laboratory leaders at two laboratory sites in Long Island, NY. Through univariate ANOVA tests, the research evaluated if there are significant differences in mental health outcomes between female and male leaders in clinical laboratory settings. The results demonstrated that female leaders experienced significantly higher levels of depression and anxiety compared to their male …

The Work-Life Balance Of Higher Education Faculty In Light Of Constant Access To Technology: A Case Study, Giordana Morales-Spier

Doctoral Dissertations and Projects

The purpose of this instrumental case study was to explore the perception of constant access to technology for faculty members in the university setting. Constant access to technology was defined as the majority of work tasks taking place in front of the computer, the expectation of quick email responses, and the pressure for continual student interaction, particularly outside of regular business hours. Burnout theory guided this study, which provided views of faculty’s efficiency, stress levels, and personal time. The central research question that guided the study was: How do higher education faculty at CVU guard against burnout while experiencing constant …

End-Of-Life Care Curricula For Respiratory Therapy Students: A Qualitative Study, Ginger Goff Coles

Doctoral Dissertations and Projects

The purpose of this descriptive case study was to understand the current end-of-life curriculum within didactic, laboratory, and clinical courses for entry-to-practice respiratory therapy students at Respiratory Therapy University (RTU), a pseudonym for the university. The theory guiding this study was Bandura’s (1988) social cognitive theory. This study used the four constructs of observational learning, perceived self-efficacy, expectancies, and behavioral capability to explain and address the problem of limited end-of-life care curricula within an entry-to-practice BSRT program. Data collection occurred through semi-structured interviews with 13 Entry-to-practice BSRT students advancing into their senior year. The findings aligned with existing theoretical and …

Health Literacy And Advocation Amongst Community Health Workers, Dustin R. King

Doctoral Dissertations and Projects

Health literacy is an important component of global health maintenance and can be greatly influenced by the DNP. The trigger for the EBP was related to a limited amount of appropriate application of health literacy in South Asian communities and village medical leaders. Health literacy was assessed by distributing short questionnaires to medical professionals such as chemists, doctors, and community health workers. An educational intervention with one specific disease process, hypertension, was then delivered to those who accepted. Upon completion of the teaching, a re-assessment with the same questions was either distributed or reviewed with the participants. Descriptive statistics were …

Experiences Of Midwest Nursing Faculty Decisions To Leave Academia: A Hermeneutic Phenomenological Study, Teresa H. Moorman

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to explore the lived experiences of Midwest nurses related to their decision to leave academic faculty positions. The theory guiding this study was Herzberg’s motivation-hygiene theory. The motivation-hygiene theory examines the factors that inform the relationship between satisfaction and lack of satisfaction, as well as dissatisfaction and lack of dissatisfaction. Herzberg outlined several motivating factors that influence employees to perform at their best, and several hygiene factors that negatively impact performance. Additionally, Dewey’s experiential learning theory underpinned the study. The lived experience comprises the physical environment, perceptions of the person, and the …

Psychotropics And Fall Reduction Through Nursing Education, Jenny L. Stillman

Doctoral Dissertations and Projects

Falls in long-term care centers (LTC) remain a significant problem due to their association with increased mortality, healthcare costs, and decreased patient outcomes. A major contributing factor to falls is the use of psychotropic medications commonly prescribed in LTC facilities despite evidence against their use. This paper discusses a quasi-experimental study aimed at reducing falls through nursing education on how psychotropics contribute to falls. The study also highlights the regulatory requirements for LTC facilities to monitor and reduce fall occurrences and the efforts made by a State Veterans Home to address the number of falls. The results demonstrate a reduction …

Examining The Relationship Of Simulation To Nursing Communication Competency: A Quantitative, Causal-Comparative, Retrospective Study, Patresha Pamella Pearson

Doctoral Dissertations and Projects

This quantitative, causal-comparative, retrospective study investigated the impact of simulation-based education on nurse communication competence by evaluating communication skills between two groups of recently graduated and licensed registered nurses while controlling for total experience hours. Though nursing communication competence significantly impacts patient care outcomes, few studies have addressed the impact of simulation on the communication competence of licensed nurses practicing in the clinical setting. The study was conducted in the clinical setting with 78 participants divided between two categorical groups of recently graduated and licensed registered nurses depending on the proportion of simulation-based education received during clinical experience requirements. The …

An Orphan Kinesin In Trypanosoma Brucei Regulates Hook Complex Assembly And Golgi Biogenesis, Qing Zhou, Yasuhiro Kurasawa, Huiqing Hu, Thiago Souza Onofre, Ziyin Li

Faculty, Staff and Student Publications

Kinesins are microtubule-based motor proteins that play diverse cellular functions by regulating microtubule dynamics and intracellular transport in eukaryotes. The early branching kinetoplastid protozoan Trypanosoma brucei has an expanded repertoire of kinetoplastid-specific kinesins and orphan kinesins, many of which have unknown functions. We report here the identification of an orphan kinesin named KIN-G that plays an essential role in maintaining hook complex integrity and promoting Golgi biogenesis in T. brucei. KIN-G localizes to the distal portion of the centrin arm of the flagellum-associated hook complex through association with the centrin arm protein TbCentrin4. Knockdown of KIN-G in T. brucei …

Non–Invasive Vulvovaginal Rejuvenation: A Review, Jesryn Dhillon, Nelva Karmila Jusuf

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Non–invasive vulvovaginal rejuvenation is a promising option for women who want to restore the appearance and function of the vagina. Vaginal atrophy and vulvovaginal laxity are caused by several circumstances, including ageing, menopause, delivery, and others. Until now, non–invasive vulvovaginal rejuvenation has not been medically indicated, but it is estimated to be the focus of cosmetic dermatology in the future.

Discussion: Non–invasive vulvovaginal rejuvenation can be divided into two methods: using energy-based devices and injectables. Carbon dioxide, Erbium:YAG laser and radiofrequency are the commonly used energy-based devices. Injectables most frequently used are hyaluronic acid and platelet–rich plasma. Some additional …

Mexican Health And Aging Study Biomarker And Genetic Data Profile, Rafael Samper-Ternent, Jesús Daniel Zazueta-Borboa, Alejandra Michaels-Obregon, Dolly Reyes-Dumeyer, Sandra Barral, Giuseppe Tosto, Rebeca Wong

Faculty, Staff and Student Publications

The Mexican Health and Aging Study (MHAS) is one of the largest ongoing longitudinal studies of aging in Latin America, with six waves over 20 years. MHAS includes sociodemographic, economic, and health data from a nationally representative sample of adults 50 years and older in urban and rural Mexico. MHAS is designed to study the impact of diseases on adults' health, function, and mortality. As Mexico is experiencing rapid population aging, providing adequate information to study this phenomenon is vital for designing and implementing public policies. The availability of biomarker and genetic data and longitudinal survey data elevates opportunities for …

Diversity And Characteristics Of The Oral Microbiome Associated With Self-Reported Ancestral/Ethnic Groups, Qingguo Wang, Bing-Yan Wang, She'neka Williams, Hua Xie

Faculty, Staff and Student Publications

Periodontitis disproportionately affects genetic ancestral/ethnic groups. To characterize the oral microbiome from different genetic ancestral/ethnic groups, we collected 161 dental plaque samples from self-identified African Americans (AAs), Caucasian Americans (CAs), and Hispanic Americans (HAs) with clinical gingival health or biofilm-induced gingivitis on an intact periodontium. DNA was extracted from these samples, and then DNA libraries were prepared and sequenced using an Illumina NovaSeq high-throughput sequencer. We found significant differences in the diversity and abundance of microbial taxa among dental plaque samples of the AA, CA, and HA groups. We also identified unique microbial species in a self-reported ancestral/ethnic group. Moreover, …

Etherealbreathing: A Holographic Biofeedback Game To Support Relaxation In Autistic Children, Arturo Morales Téllez, Isabel López Hurtado, Franceli L. Cibrian, Monica Tentori

Engineering Faculty Articles and Research

Biofeedback training for box breathing is becoming increasingly accessible due to advancements in consumer-grade breathing sensors. However, there is limited research on their design and applications for specialized populations. This study evaluates a novel biofeedback holographic game, EtherealBreathing, designed to support autistic children. In EtherealBreathing, children practice box breathing to collect virtual elements to maintain the Earth's balance, using a wearable sensor to measure chest expansion for breath detection. A deployment study with 20 autistic children revealed that EtherealBreathing effectively promotes box breathing, leading to better health-related outcomes, such as lowering participants’ heart and respiratory rates than traditional practices. Biofeedback …

Colonic Derotation Revisited: The "Deloyers Procedure" For Long-Segment Hirschsprung Disease., Ismael Elhalaby, Irene Isabel P. Lim, Elizaveta Bokova, Ifeanyi K Egbuchulem, Rebecca M. Rentea

Manuscripts, Articles, Book Chapters and Other Papers

Long-segment Hirschsprung disease (HSCR) presents significant challenges in surgical management, often requiring extensive bowel mobilization and creative techniques to achieve tension-free anastomosis. Colonic derotation offers a viable solution for preserving bowel length and maintaining the ileocecal valve, which is crucial for postoperative bowel function. The procedure involves extensive colonic mobilization and strategic vascular divisions of the right and middle colic vessels while preserving the ileocolic and marginal arteries, followed by a 180° counterclockwise rotation of the colon around the ileocolic vascular axis. Critical aspects include ensuring proper bowel orientation post-derotation, the careful assessment of potential compression points, and the preservation …

The Lived Experiences Of Male Nurses In Nursing Education: A Hermeneutic Phenomenological Study, James Robert Nolin

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to discover the lived experiences of male nurses currently in nursing academia to determine what attributes draw them and keep them in academic roles. The phenomenon was viewed through the lens of interpersonal relations theory, social learning theory, and hermeneutic phenomenology, looking for similarities and differences to discover the population’s views, beliefs, and experiences. The sample included 21 male nurses currently teaching in nursing programs. Semi-structured interviews, focus groups, and observations collected through field notes allowed for an in-depth understanding of the lived experiences of male nursing faculty. The data were analyzed …

Nomenclature For Human And Animal Fungal Pathogens And Diseases: A Proposal For Standardized Terminology, Sybren De Hoog, Thomas J Walsh, Sarah A Ahmed, Ana Alastruey-Izquierdo, Maiken Cavling Arendrup, Andrew Borman, Sharon Chen, Anuradha Chowdhary, Robert C Colgrove, Oliver A Cornely, David W Denning, Philippe J Dufresne, Laura Filkins, Jean-Pierre Gangneux, Josepa Gené, Andreas H Groll, Jaques Guillot, Gerhard Haase, Catriona Halliday, David L Hawksworth, Roderick Hay, Martin Hoenigl, Vit Hubka, Tomasz Jagielski, Hazal Kandemir, Sarah E Kidd, Julianne V Kus, June Kwon-Chung, Shawn R Lockhart, Jacques F Meis, Leonel Mendoza, Wieland Meyer, M Hong Nguyen, Yinggai Song, Tania C Sorrell, J Benjamin Stielow, Rachel Vilela, Roxana G Vitale, Nancy L Wengenack, P Lewis White, Luis Ostrosky-Zeichner, Sean X Zhang

Faculty, Staff and Student Publications

Medically important pathogenic fungi invade vertebrate tissue and are considered primary when part of their nature life cycle is associated with an animal host and are usually able to infect immunocompetent hosts. Opportunistic fungal pathogens complete their life cycle in environmental habitats or occur as commensals within or on the vertebrate body, but under certain conditions can thrive upon infecting humans. The extent of host damage in opportunistic infections largely depends on the portal and modality of entry as well as on the host's immune and metabolic status. Diseases caused by primary pathogens and common opportunists, causing the top approximately …

Staphylococcus Epidermidis St2 Strains Associated With Bloodstream Infections Contain A Unique Mobile Genetic Element Encoding A Plasmin Inhibitor, Amy A Gomez, Clara Kjerfve, Minseo Choi, Wen Liu, Kelly Churion, Sheila Thomas, Holger Rohde, Sam Shelburne, Jon T Skare, Magnus Hook, Srishtee Arora

Faculty, Staff and Student Publications

Staphylococcus epidermidis, a common commensal bacterium, is a leading cause of nosocomial catheter-associated bloodstream infections. S. epidermidis sequence type 2 (ST2) is specifically recognized globally for causing invasive disease. In this study, we identified a novel putative integrated conjugative element, pICE-Sepi-ST2, unique to the genomes of S. epidermidis ST2. Our investigation identified pICE-Sepi-ST2 in all ST2 isolates from bloodstream infections. Meanwhile, ST2 isolates from other infection sources, such as catheters, prosthetic joints, and fracture fixations, showed variable pICE-Sepi-ST2 prevalence. pICE-Sepi-ST2 encodes two putative cell wall anchored proteins that we have designated SesX and SesY. Biochemical characterization of SesY revealed …

Assessing A Reading Score's Ability To Predict Pta Program Student Success, Tiffany H. Bain

Doctoral Dissertations and Projects

Admission into a physical therapist assistant (PTA) program continues to be highly competitive, with consistently more applicants than available seats. Student success is essential for maintaining CAPTE accreditation. There is limited research on admission criteria and predictors of success in physical therapist assistant education. This study aimed to determine if the Accuplacer or ACT reading test scores can predict student success (program completion and first-time NPTE-PTA) in a physical therapist assistant program using Astin’s input-environment-output (IEO) model as the theoretical foundation. This non-experimental logistic regression study used retrospective secondary data from an associate degree-level physical therapist assistant program 2016 through …

Challenged And Chosen: Discipling Christians With Chronic Conditions Towards Kingdom Identity And Purpose, Allison J. Hampton

Doctoral Dissertations and Projects

The purpose for this DMIN action research project was to create an eight-week discipleship program and accompanying workbook to help Christians diagnosed with chronic medical conditions to rediscover their identity in God. Because of the limitations and physical changes that often accompany chronic diagnoses, members of Living Chronic Faith (a faith-first nonprofit organization that serves believers with chronic diagnoses) felt incapable of serving on the same level as their physiotypical counterparts. Marginalized by their faith community and hesitant to engage in their ministry contexts, eleven LCF members participated in this online focus group. This project’s surveys, interviews, journal entries, and …

Exploring The Utility Of The Septicyte In Clinical Decision-Making In The Emergency Department, Sylvia Lowery-Taylor

Doctoral Dissertations and Projects

Know thy enemy. A significant obstacle in treating and managing sepsis is the absence of a test or method to diagnose the disease rapidly. Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection (Sinha & Ray, 2018). Despite improvements to sepsis-related care and sepsis outcomes, it remains a worldwide concern and a leading cause of mortality. Early recognition and management of sepsis is critical to provide rapid treatment and to prevent deaths associated with sepsis and septic shock. Since most patients with sepsis receive their initial care in the emergency department, it is …

Physiological And Biomechanical Perspectives On Elbow Function During Forehand And Backhand Disc Golf Throws: A Novel Investigation, Lauren Rachelle Giles

Doctoral Dissertations and Projects

Over 81% of players have reported injuries linked to disc golfing, predominantly due to overuse. Since disc golf originated, there is a lack of research on the proper biomechanics of the disc golf throw. This descriptive, quantitative study seeks to be the first. We investigated 6 females and 35 males, aged 21-66, registered to compete in disc golf. The goal was to examine the kinetic parameters of healthy disc golfers to identify biomechanics likely associated with safety. Research questions investigated whether there is a connection between lean body mass and disc distance traveled, elbow torque and disc distance, or grip …