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2024

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Full-Text Articles in Medicine and Health Sciences

Kesintasan Pasien Karsinoma Hepatoselular: Sebuah Studi Komprehensif Tentang Pengaruh Awitan Dini Versus Lambat Dan Faktor Determinannya, Ibrahim Achmad, Chyntia Olivia Maurine Jasirwan, Wulyo Rajabto, Murdani Abdullah, Saut Horas H. Nababan, Sally Aman Nasution, Sukamto Koesnoe, Nina Kemala Sari Sep 2024

Kesintasan Pasien Karsinoma Hepatoselular: Sebuah Studi Komprehensif Tentang Pengaruh Awitan Dini Versus Lambat Dan Faktor Determinannya, Ibrahim Achmad, Chyntia Olivia Maurine Jasirwan, Wulyo Rajabto, Murdani Abdullah, Saut Horas H. Nababan, Sally Aman Nasution, Sukamto Koesnoe, Nina Kemala Sari

Jurnal Penyakit Dalam Indonesia

Introduction. The prognosis for patients with Hepatocellular Carcinoma (HCC) is generally poor because most cases are diagnosed at an advanced stage. Several studies indicate that HCC is more prevalent and has a worse prognosis among younger individuals. This study aims to identify and compare the variations in survival rates between early and late-onset HCC patients at Cipto Mangunkusumo Hospital and investigate the factors that impact survival outcomes in both groups.

Methods. Retrospective cohort study of HCC patients registered in HCC registry 2015-2022. Survival was visualized using Kaplan-Meier curves. Prognostic factor variables in the Cox Proportional Hazard Regression analysis …


Potassium-Competitive Acid Blocker Sebagai Alternatif Penghambat Pompa Proton Untuk Mengatasi Gejala Gastroesophageal Reflux Disease: Sebuah Laporan Kasus Berbasis Bukti, Adam Prabata, Adelia Nova Prahasary, Arya Govinda Sep 2024

Potassium-Competitive Acid Blocker Sebagai Alternatif Penghambat Pompa Proton Untuk Mengatasi Gejala Gastroesophageal Reflux Disease: Sebuah Laporan Kasus Berbasis Bukti, Adam Prabata, Adelia Nova Prahasary, Arya Govinda

Jurnal Penyakit Dalam Indonesia

Gastric acid suppression is one of the main pillars of gastroesophageal reflux disease (GERD) treatment. Proton pump inhibitor (PPI) is the most used drug for suppressing gastric acid in GERD patients currently. Potassium- acid competitive acid blocker (PCAB) is a new class of drug which can be used as an alternative drug for suppressing gastric acid, so hypothetically, this drug could be an alternative of PPI for relieving GERD symptoms. However, the ability of PCAB for relieving GERD symptoms was not established, so this study was aimed to elucidate the ability of PCAB as an alternative drug of PPI for …


Ventilasi Noninvasif Pada Obstructive Sleep Apnea Dan Obesity Hypoventilation Syndrome, Herikurniawan Herikurniawan, Joanna Audrey, Firina Adelya Sep 2024

Ventilasi Noninvasif Pada Obstructive Sleep Apnea Dan Obesity Hypoventilation Syndrome, Herikurniawan Herikurniawan, Joanna Audrey, Firina Adelya

Jurnal Penyakit Dalam Indonesia

Chronic respiratory disease such as obstructive sleep apnea (OSA) and obesity-hypoventilation syndrome (OHS) remain are respiratory sleeping disorder that gradually affect quality of life. Comprehensive treatment such as the use of non-invasive ventilation (NIV) is a method adopted to improve the patient’s quality of life. The correct choice of NIV mode, mask and titration methods will provide optimal therapeutic effects to the patient. This article review lays out an update on the use of non-invasive ventilation as the treatment of OSA and OHS.


Penggunaan Antibiotik Empiris Yang Rasional Pada Era Infeksi Oleh Organisme Multi Drug Resistant, Robert Sinto Sep 2024

Penggunaan Antibiotik Empiris Yang Rasional Pada Era Infeksi Oleh Organisme Multi Drug Resistant, Robert Sinto

Jurnal Penyakit Dalam Indonesia

Resistensi antimikroba (antimicrobial resistance, AMR), secara khusus antibiotik, telah menjadi masalah dunia saat ini. Masalah resistensi antibiotik terjadi pada seluruh jenis antibiotik yang ada, dan terjadi di seluruh negara, termasuk Indonesia. Dalam skala global, Perserikatan Bangsa-Bangsa mengeluarkan World Health Assembly Resolution WHA 68.7 dengan judul Global Action Plan on Antimicrobial Resistance sebagai wujud perhatian yang mendalam terhadap masalah global ini.


The Effectiveness Of Massage Gun Treatment Combined With Passive Stretching In Reducing Non-Specific Lower Back Pain, Yudik Prasetyo, Sabda Husain As Shafi, Fatkhurahman Arjuna, Atikah Rahayu, Mohd Izwan Bin Shahril, Mohad Anizu Mohd Nor, Edwin Onyango Otieno Sep 2024

The Effectiveness Of Massage Gun Treatment Combined With Passive Stretching In Reducing Non-Specific Lower Back Pain, Yudik Prasetyo, Sabda Husain As Shafi, Fatkhurahman Arjuna, Atikah Rahayu, Mohd Izwan Bin Shahril, Mohad Anizu Mohd Nor, Edwin Onyango Otieno

Jurnal Keolahragaan

Non-specific lower back pain is a common condition characterized by strain, muscle spasms, or weakness of the paraspinal muscles, particularly the multifidus muscle, which affects adjacent musculature such as the gluteus, hamstrings, and quadriceps. This study aimed to investigate whether massage gun treatment combined with passive stretching could reduce non-specific low back pain in patients experiencing subacute and chronic phases of this condition. This pseudo-experimental research employed a one-group pretest-posttest design with three treatments. Participants were selected using purposive sampling based on inclusion criteria: suffering from non-specific low back pain, willingness to participate, and age between 20 and 65 years. …


Abses Iliopsoas Akibat Tuberkulosis: Sebuah Laporan Kasus, Desty Gusti Sari, Rosatya Imanuela, Resultanti Resultanti Sep 2024

Abses Iliopsoas Akibat Tuberkulosis: Sebuah Laporan Kasus, Desty Gusti Sari, Rosatya Imanuela, Resultanti Resultanti

Jurnal Penyakit Dalam Indonesia

Psoas abscess is a rare condition with an unclear clinical presentation where there is a collection of pus in the iliopsoas compartment. The most common cause of an iliopsoas abscess is infection with Staphylococcus aureus. Mycobacterium tuberculosis rarely causes psoas abscesses, with an incidence of about 10–30% of extrapulmonary tuberculosis and only 3% of tuberculosis in general. Psoas abscesses due to tuberculosis is quite rare and has non-specific symptoms, so it sometimes causes a late diagnosis. This case study reports on male aged 43-year-old patient who had previously been diagnosed with spondylitis tuberculosis (TBC) and complained of pain accompanied by …


The American Cancer Society National Lung Cancer Roundtable Strategic Plan: Optimizing Strategies For Lung Nodule Evaluation And Management, Julie A. Barta, Farhood Farjah, Carey Conley Thomson, Debra S. Dyer, Renda Soylemez Wiener, Christopher G. Slatore, Rebecca Smith-Bindman, Lauren S. Rosenthal, Gerard A. Silvestri, Robert A. Smith, Michael K. Gould Sep 2024

The American Cancer Society National Lung Cancer Roundtable Strategic Plan: Optimizing Strategies For Lung Nodule Evaluation And Management, Julie A. Barta, Farhood Farjah, Carey Conley Thomson, Debra S. Dyer, Renda Soylemez Wiener, Christopher G. Slatore, Rebecca Smith-Bindman, Lauren S. Rosenthal, Gerard A. Silvestri, Robert A. Smith, Michael K. Gould

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

Lung nodules are frequently detected on low-dose computed tomography scans performed for lung cancer screening and incidentally detected on imaging performed for other reasons. There is wide variability in how lung nodules are managed by general practitioners and subspecialists, with high rates of guideline-discordant care. This may be due in part to the level of evidence underlying current practice guideline recommendations (primarily based on findings from uncontrolled studies of diagnostic accuracy). The primary aims of lung nodule management are to minimize harms of diagnostic evaluations while expediting the evaluation, diagnosis, and treatment of lung cancer. Potentially useful tools such as …


Digital Education On Hospital Nutrition Diets: What Do Patients Want To Know?, Neha Gutta, Som Singh, Dharti Patel, Aleena Jamal, Fawad Qureshi Sep 2024

Digital Education On Hospital Nutrition Diets: What Do Patients Want To Know?, Neha Gutta, Som Singh, Dharti Patel, Aleena Jamal, Fawad Qureshi

SKMC Student Presentations and Publications

INTRODUCTION: Therapeutic nutrition plays an imperative role during a patient's hospital course. There is a tremendous body of literature that emphasizes the systematic delivery of information regarding hospital nutrition diets. A major component of delivering healthcare information is the principle of providing quality healthcare information, but this has not yet been investigated on hospital nutrition diets. This study aimed to evaluate the comprehension and readability of patient education materials regarding therapeutic hospital diets.

METHODOLOGY: The methodology employed the use of publicly available questions regarding hospital nutrition diets and categorized them per Rothwell's Classification of Questions. Additionally, the questions were extracted …


Nongenetic And Genetic Factors Associated With White Matter Brain Aging: Exposome-Wide And Genome-Wide Association Study, Li Feng, Halley S Milleson, Zhenyao Ye, Travis Canida, Hongjie Ke, Menglu Liang, Si Gao, Shuo Chen, L Elliot Hong, Peter Kochunov, David K Y Lei, Tianzhou Ma Sep 2024

Nongenetic And Genetic Factors Associated With White Matter Brain Aging: Exposome-Wide And Genome-Wide Association Study, Li Feng, Halley S Milleson, Zhenyao Ye, Travis Canida, Hongjie Ke, Menglu Liang, Si Gao, Shuo Chen, L Elliot Hong, Peter Kochunov, David K Y Lei, Tianzhou Ma

Faculty, Staff and Student Publications

BACKGROUND/OBJECTIVES: Human brain aging is a complex process that affects various aspects of brain function and structure, increasing susceptibility to neurological and psychiatric disorders. A number of nongenetic (e.g., environmental and lifestyle) and genetic risk factors are found to contribute to the varying rates at which the brain ages among individuals.

METHODS: In this paper, we conducted both an exposome-wide association study (XWAS) and a genome-wide association study (GWAS) on white matter brain aging in the UK Biobank, revealing the multifactorial nature of brain aging. We applied a machine learning algorithm and leveraged fractional anisotropy tract measurements from diffusion tensor …


Analysis Protecting The Health Workers From The Transmission Of Tuberculosis At Teaching Hospital: A Review Of Policy And Practice, Arifah Alfiyyah, Robiana Modjo, Adang Bachtiar Sep 2024

Analysis Protecting The Health Workers From The Transmission Of Tuberculosis At Teaching Hospital: A Review Of Policy And Practice, Arifah Alfiyyah, Robiana Modjo, Adang Bachtiar

Journal of Indonesian Health Policy and Administration

The Tuberculosis (TB) remains a significant threat, especially to healthcare workers exposed by the infected patients in hospitals. Hospital staff with latent TB are at risk of developing active TB. To mitigate this risk, enhancing hospitals through infection prevention and control (IPC) measures is essential. This study aimed to identify policies and practices related to TB prevention, particularly in a teaching hospital where healthcare workers, including medical students, need protection. The research was conducted at a teaching hospital in Depok, West Java, from January to February 2024. The research took place at a teaching hospital in Depok, West Java, from …


Optimizing The Use Of Online Systems In Health Care Facilities, Wendy Damar Aprilano, Mardiati Nadjib Sep 2024

Optimizing The Use Of Online Systems In Health Care Facilities, Wendy Damar Aprilano, Mardiati Nadjib

Journal of Indonesian Health Policy and Administration

The use of web-based information technology or online services can accelerate service delivery. Digitalisation of online health services is one of the growing issues, along with the increasing need for access to health services globally. However, there are things that must be considered in implementing an online health service system so the utilisation can be optimal. This study examines the factors that can support the optimisation of online service systems in health facilities so that innovation can continue to grow and provide benefits in the future. The authors conducted a literature review, with PRISMA guidelines according to the PEO …


Implementation Of Sugar-Sweetened Beverages Excise Policy And Its Implications In Various Countries: Literature Review, Roissiana Khotami, Vetty Yulianty, Ratih Oktarina Sep 2024

Implementation Of Sugar-Sweetened Beverages Excise Policy And Its Implications In Various Countries: Literature Review, Roissiana Khotami, Vetty Yulianty, Ratih Oktarina

Journal of Indonesian Health Policy and Administration

The prevalence of diabetes in the world is projected to continue to increase to 643 million in 2030. Indonesia is ranked 7th with the highest number of diabetes mellitus sufferers and the only one in Southeast Asia with a total of 10.7 million sufferers. Consumption of sweetened drinks is the most dominant factor in the incidence of diabetes mellitus in Indonesia. Indonesia ranks third highest in Southeast Asia in sweetened drink consumption. Excise on sweetened drinks is an effective intervention to reduce consumption of sweetened drinks, but Indonesia has not yet implemented it. This research aims to determine the implementation …


Prospective Trial Of Sacroiliac Joint Fusion Using 3d-Printed Triangular Titanium Implants: 5-Year Follow-Up, Vikas Patel, S. Craig Meyer, Don Kovalsky, Harry Lockstadt, Jim Farris, Robert Limoni, Abhineet Chowdhary, Philip Yuan, Casey Langel, Andy Kranenburg, Gabriel Tender Sep 2024

Prospective Trial Of Sacroiliac Joint Fusion Using 3d-Printed Triangular Titanium Implants: 5-Year Follow-Up, Vikas Patel, S. Craig Meyer, Don Kovalsky, Harry Lockstadt, Jim Farris, Robert Limoni, Abhineet Chowdhary, Philip Yuan, Casey Langel, Andy Kranenburg, Gabriel Tender

School of Medicine Faculty Publications

Study Design. Prospective, multicenter, single arm study with 5-year follow up Objective. To report long-term (5-year) safety, effectiveness, and radiographic outcomes after sacroiliac (SI) joint fusion (SIJF) with 3D-printed triangular titanium implants (TTI) and compare them with solid titanium plasma spray coated implants Summary of Background Data. A large literature base supports minimally invasive SIJF with TTI for chronic SIJ dysfunction. Methods. SIJF with TTI was performed in 51 subjects and scheduled follow-up occurred at 3, 6, 12, 24 and 60 months. Postoperative visits included quality of life questionnaires and functional tests. A high-resolution CT scan was performed at either …


Nilai Diagnostik Italian Score Untuk Memprediksi Infeksi Bakteri Extended Spectrum Beta-Lactamase (Esbl) Pada Pasien Sepsis Di Rsup Dr. M. Djamil Padang, Fadrian Fadrian, Armen Ahmad, Khairat Khairat Sep 2024

Nilai Diagnostik Italian Score Untuk Memprediksi Infeksi Bakteri Extended Spectrum Beta-Lactamase (Esbl) Pada Pasien Sepsis Di Rsup Dr. M. Djamil Padang, Fadrian Fadrian, Armen Ahmad, Khairat Khairat

Jurnal Penyakit Dalam Indonesia

Introduction. Infections caused by Extended-Spectrum Beta-Lactamase (ESBL) bacteria, especially in septic patients, require adequate management. Giving definitive antibiotics according to culture results takes a long time. Therefore, a clinical scoring system is needed to predict ESBL bacterial infection, one of which is the Italian score.

Methods. This research used a cross-sectional design and was conducted in the inpatient room of RSUP Dr. M. Djamil Padang for 6 months. The samples in this study were septic patients who underwent culture examination at RSUP Dr. M. Djamil Padang who met the research inclusion and exclusion criteria. Sampling was carried out …


High Fat, High Sucrose Diet Promotes Increased Expression Of Ace2 Receptor In The Siv-Infected Host: Implications For Sars-Cov-2 Infection, Elizabeth C. Delery, Danielle E. Levitt, Angela M. Amedee, Patricia E. Molina, Liz Simon Sep 2024

High Fat, High Sucrose Diet Promotes Increased Expression Of Ace2 Receptor In The Siv-Infected Host: Implications For Sars-Cov-2 Infection, Elizabeth C. Delery, Danielle E. Levitt, Angela M. Amedee, Patricia E. Molina, Liz Simon

School of Graduate Studies Faculty Publications

Introduction: People with pre-existing conditions, including metabolic comorbidities, are at greater risk for complications of SARS-CoV-2 infection and expression of machinery required for viral entry into host cells may be a contributing factor. This study tested the hypothesis that high fat, high sucrose diet (HFSD) and alcohol use increase expression of angiotensin converting enzyme 2 (ACE2) receptor and transmembrane serine protease 2 (TMPRSS2) in tissues isolated from simian immunodeficiency virus (SIV) infected macaques, the most clinically relevant model for the study of HIV. Methods: Biospecimens obtained from a longitudinal study of SIV-infected, antiretroviral therapy (ART)-treated female rhesus macaques (Macaca mulatta) …


Early Intervention System Contextual Factors Contributing To Treatment Attendance And Clinical Outcomes, Anthony Eldridge Sep 2024

Early Intervention System Contextual Factors Contributing To Treatment Attendance And Clinical Outcomes, Anthony Eldridge

Theses and Dissertations

Early Intervention Programs (EI) are an established method of addressing and treating earlier childhood developmental problems that involves a system of complex processes which families must navigate to secure and maintain care. Extensive wait times and multiple service providers burdensome caregivers which may impact treatment engagement. Telehealth offers some clinical utility for improving EI service provision. However, little is known how system contextual factors predict a child’s Part B Eligibility and level of engagement with treatment. The primary aim of this study is to describe the effect that wait time, number of service providers, number of treatment services, and treatment …


Enhancing Recovery: Surgical Techniques And Rehabilitation Strategies After Direct Anterior Hip Arthroplasty, Alberto Di Martino, Christopher Keating, Micahel J. Butsick, Daniela Platano, Lisa Berti, Louis N. Hunter, Cesare Faldini Sep 2024

Enhancing Recovery: Surgical Techniques And Rehabilitation Strategies After Direct Anterior Hip Arthroplasty, Alberto Di Martino, Christopher Keating, Micahel J. Butsick, Daniela Platano, Lisa Berti, Louis N. Hunter, Cesare Faldini

Department of Physical Therapy Faculty Papers

Total hip arthroplasty (THA) is a common surgical procedure for hip joint pathologies, with the direct anterior approach (DAA) gaining popularity due to potential benefits in postoperative recovery. This review aims to provide a comprehensive analysis of rehabilitation strategies following DAA THA, focusing on surgical techniques, postoperative care, and outcomes. The evolution of the DAA to THA is discussed, highlighting historical advancements and comparisons with other surgical approaches. Surgical techniques and considerations specific to the DAA are detailed, including outcomes and complications compared to alternative approaches. The role of the surgical technique in influencing postoperative rehabilitation is explored, emphasizing the …


Hormone Replacement Therapy And Risk Of Pancreatic Cancer In Postmenopausal Women: Evidence From The Us National Inpatient Sample 2008–2018, Lei Liu, Xinyu Wang, Dekai Guo, Ruirui Ma, Haibing Gong, Congjun Wang Sep 2024

Hormone Replacement Therapy And Risk Of Pancreatic Cancer In Postmenopausal Women: Evidence From The Us National Inpatient Sample 2008–2018, Lei Liu, Xinyu Wang, Dekai Guo, Ruirui Ma, Haibing Gong, Congjun Wang

Faculty, Staff and Student Publications

BACKGROUND: Pancreatic cancer is a serious, usually fatal disease and one of the most aggressive malignancies. Research into whether hormone replacement therapy (HRT) might protect against pancreatic cancer has yielded mixed results. This study aimed to investigate the potential association between HRT and the risk of pancreatic cancer in postmenopausal women.

METHODS: This population-based, retrospective study extracted data from the US National Inpatient Sample (NIS) 2008-2018. Hospitalized females aged ≥55 years were eligible for inclusion. Associations between HRT, other study variables, and pancreatic cancer diagnosis were determined using univariate and multivariable regression analyses.

RESULTS: After 1:4 matching by age, data …


Impact Of Essential Genes On The Success Of Genome Editing Experiments Generating 3313 New Genetically Engineered Mouse Lines, Hillary Elrick, Kevin A Peterson, Brandon J Willis, Denise G Lanza, Elif F Acar, Edward J Ryder, Lydia Teboul, Petr Kasparek, Marie-Christine Birling, David J Adams, Allan Bradley, Robert E Braun, Steve D Brown, Adam Caulder, Gemma F Codner, Francesco J Demayo, Mary E Dickinson, Brendan Doe, Graham Duddy, Marina Gertsenstein, Leslie O Goodwin, Yann Hérault, Lauri G Lintott, K C Kent Lloyd, Isabel Lorenzo, Matthew Mackenzie, Ann-Marie Mallon, Colin Mckerlie, Helen Parkinson, Ramiro Ramirez-Solis, John R Seavitt, Radislav Sedlacek, William C Skarnes, Damien Smedley, Sara Wells, Jacqueline K White, Joshua A Wood, International Mouse Phenotyping Consortium, Stephen A Murray, Jason D Heaney, Lauryl M J Nutter Sep 2024

Impact Of Essential Genes On The Success Of Genome Editing Experiments Generating 3313 New Genetically Engineered Mouse Lines, Hillary Elrick, Kevin A Peterson, Brandon J Willis, Denise G Lanza, Elif F Acar, Edward J Ryder, Lydia Teboul, Petr Kasparek, Marie-Christine Birling, David J Adams, Allan Bradley, Robert E Braun, Steve D Brown, Adam Caulder, Gemma F Codner, Francesco J Demayo, Mary E Dickinson, Brendan Doe, Graham Duddy, Marina Gertsenstein, Leslie O Goodwin, Yann Hérault, Lauri G Lintott, K C Kent Lloyd, Isabel Lorenzo, Matthew Mackenzie, Ann-Marie Mallon, Colin Mckerlie, Helen Parkinson, Ramiro Ramirez-Solis, John R Seavitt, Radislav Sedlacek, William C Skarnes, Damien Smedley, Sara Wells, Jacqueline K White, Joshua A Wood, International Mouse Phenotyping Consortium, Stephen A Murray, Jason D Heaney, Lauryl M J Nutter

Faculty, Staff and Students Publications

The International Mouse Phenotyping Consortium (IMPC) systematically produces and phenotypes mouse lines with presumptive null mutations to provide insight into gene function. The IMPC now uses the programmable RNA-guided nuclease Cas9 for its increased capacity and flexibility to efficiently generate null alleles in the C57BL/6N strain. In addition to being a valuable novel and accessible research resource, the production of 3313 knockout mouse lines using comparable protocols provides a rich dataset to analyze experimental and biological variables affecting in vivo gene engineering with Cas9. Mouse line production has two critical steps - generation of founders with the desired allele and …


Intouch Week Of September 30, 2024, New York Medical College Sep 2024

Blood Pressure During Hospital Stay For Delivery And Risk For Postpartum Readmission For Hypertension, Kaitlyn Taylor, Sai S. Pochana, Andrew Chapple, Maureen Dempsey, Elizabeth F. Sutton Sep 2024

Blood Pressure During Hospital Stay For Delivery And Risk For Postpartum Readmission For Hypertension, Kaitlyn Taylor, Sai S. Pochana, Andrew Chapple, Maureen Dempsey, Elizabeth F. Sutton

School of Medicine Faculty Publications

OBJECTIVE: To evaluate the association of changes in peripartum blood pressure (BP) with risk for postpartum readmission for hypertension. METHODS: We conducted a retrospective cohort study of birthing individuals delivering from January 1, 2017, to March 1, 2020, in Louisiana. We identified patients with postpartum readmission for hypertension (readmission within 30 days of delivery) and compared BP and clinical and sociodemographic characteristics with those of patients who were not readmitted for hypertension. Patients were also grouped by their BP at both admission for delivery and 36 hours postpartum: systolic below 130 mm Hg and diastolic below 80 mm Hg, systolic …


Downregulation Of Piezo2 In The Detrusor Of Men With Bladder Outlet Obstruction And Its Association With Urinary Retention And Decreased Bladder Compliance, Carlos Henrique Suzuki Bellucci, Thiago Souto Hemerly, Luisa Resende Tenório De Albuquerque, Ruan Pimenta, Vanessa Guimaraes Schreiter, Sabrina Thalita Dos Reis, Jose De Bessa Jr, Katia Ramos Moreira Leite, Alberto Antunes, Boopathi Ettickan, William C. Nahas, Cristiano Mendes Gomes Sep 2024

Downregulation Of Piezo2 In The Detrusor Of Men With Bladder Outlet Obstruction And Its Association With Urinary Retention And Decreased Bladder Compliance, Carlos Henrique Suzuki Bellucci, Thiago Souto Hemerly, Luisa Resende Tenório De Albuquerque, Ruan Pimenta, Vanessa Guimaraes Schreiter, Sabrina Thalita Dos Reis, Jose De Bessa Jr, Katia Ramos Moreira Leite, Alberto Antunes, Boopathi Ettickan, William C. Nahas, Cristiano Mendes Gomes

Center for Translational Medicine Faculty Papers

PURPOSE: Recent research has highlighted the mechanotransducer PIEZO2 as a crucial factor in lower urinary tract function, demonstrating associations with bladder compliance (BC), bladder wall thickening, and elevated bladder pressure. We explored the hypothesis that PIEZO2 expression may be associated with lower urinary tract dysfunction in men with bladder outlet obstruction (BOO) due to benign prostatic hyperplasia (BPH).

METHODS: The study included a consecutive series of patients undergoing open prostatectomy for BPH at our hospital between September 2014 and January 2016. All participants underwent comprehensive preoperative evaluations, including urodynamic assessments. During prostatectomy, a full-thickness fragment of the bladder wall was …


Exploring Racial Disparities In Awareness And Perceptions Of Oncology Clinical Trials: Cross-Sectional Analysis Of Baseline Data From The Mychoice Study, Ariel Hoadley, Linda Fleisher, Cassidy Kenny, Patrick Ja Kelly, Xinrui Ma, Jingwei Wu, Carmen Guerra, Amy E. Leader, Mohammed Alhajji, Paul D'Avanzo, Zoe Landau, Sarah Bauerle Bass Sep 2024

Exploring Racial Disparities In Awareness And Perceptions Of Oncology Clinical Trials: Cross-Sectional Analysis Of Baseline Data From The Mychoice Study, Ariel Hoadley, Linda Fleisher, Cassidy Kenny, Patrick Ja Kelly, Xinrui Ma, Jingwei Wu, Carmen Guerra, Amy E. Leader, Mohammed Alhajji, Paul D'Avanzo, Zoe Landau, Sarah Bauerle Bass

Kimmel Cancer Center Faculty Papers

BACKGROUND: Black/African American adults are underrepresented in oncology clinical trials in the United States, despite efforts at narrowing this disparity.

OBJECTIVE: This study aims to explore differences in how Black/African American oncology patients perceive clinical trials to improve support for the clinical trial participation decision-making process.

METHODS: As part of a larger randomized controlled trial, a total of 244 adult oncology patients receiving active treatment or follow-up care completed a cross-sectional baseline survey on sociodemographic characteristics, clinical trial knowledge, health literacy, perceptions of cancer clinical trials, patient activation, patient advocacy, health care self-efficacy, decisional conflict, and clinical trial intentions. Self-reported …


Artificial Fruit Ripening Agents And Their Impact On Health Of The University Students In Lahore, Muhammad Ahsan, Faraz Ahmad, Faiza Usman, Shamaila Habib, Imran Shahid, Sohail Abbas, Sajida Munir Sep 2024

Artificial Fruit Ripening Agents And Their Impact On Health Of The University Students In Lahore, Muhammad Ahsan, Faraz Ahmad, Faiza Usman, Shamaila Habib, Imran Shahid, Sohail Abbas, Sajida Munir

Journal of Bioresource Management

To evaluate the impact of chemicals used in artificial fruit ripening and to create an approach for raising public awareness of the risks associated with artificial fruit ripening. It was a cross-sectional and observational study, in which data was gathered from 900 university students by convenient sampling technique in Lahore. The duration of research was from May 2021 to Dec 2021. The adverse reactions caused due to different fruits were recorded on a questionnaire. Candidates included in this research were, aged between 18 years to 28 years and healthy, whereas unhealthy were excluded. Out of 900 participants, 247 (27.4 %) …


A Review On Poultry; Semen Storage And Preservation, Zafar Ali Khoso, Nasir Rajput, Imdad Hussain Leghari, Asmatullah Kaka, Tarique Khokhar Sep 2024

A Review On Poultry; Semen Storage And Preservation, Zafar Ali Khoso, Nasir Rajput, Imdad Hussain Leghari, Asmatullah Kaka, Tarique Khokhar

Journal of Bioresource Management

For the improvement of genetic resources and their maintenance, new techniques of assisted reproductive technologies have been developed. Cryopreservation of semen, embryo transfer and artificial insemination in mammals are used, while in the avian technique of artificial insemination after semen cryopreservation is proved fruitful. By using this developed technique, the best fertility rate in chicken can be obtained by artificial insemination. In vitro cryopreservation can affect the motility, life of sperm, viability, fertilizing ability. From mammalian sperm cell, the avian sperm cell is different in shape, size having polyunsaturated fatty acid. The use of suitable cryo-protectants and semen extender can …


Increasing The Frequency Of Behavior Assessment To Reduce Physical Restraint, Breanne N. Ford Sep 2024

Increasing The Frequency Of Behavior Assessment To Reduce Physical Restraint, Breanne N. Ford

Doctor of Nursing Practice Final Project Abstract

Purpose: The purpose of this quality improvement (QI) project was to implement a system that routinely assesses for behavior changes in psychiatric patients presenting to the emergency department to improve staff intervention of escalating behaviors and decrease physical restraint use.

Background: The project was implemented in a 45-bed emergency department in a community-based hospital affiliated with a large hospital system in Houston, Texas.

Methodology: The project utilizes the Behavioral Activity Rating Scale (BARS) to assess patients' behaviors at routine intervals throughout shifts and a comfort cart that houses several non-pharmacological intervention items to use to de-escalate adverse behaviors. The staff …


Quinoxaline 1,4-Di-N-Oxide Derivatives As New Antinocardial Agents, Isidro Palos, Alonzo Gonzalez-Gonzalez, Alma D. Paz-Gonzalez, José C. Espinoza-Hicks, Debasish Bandyopadhyay, Norma Paniagua-Castro, Marlene S. Galeana-Salazar, Jorge Ismael Castañeda-Sánchez, Julieta Luna-Herrera, Gildardo Rivera-Sanchez Sep 2024

Quinoxaline 1,4-Di-N-Oxide Derivatives As New Antinocardial Agents, Isidro Palos, Alonzo Gonzalez-Gonzalez, Alma D. Paz-Gonzalez, José C. Espinoza-Hicks, Debasish Bandyopadhyay, Norma Paniagua-Castro, Marlene S. Galeana-Salazar, Jorge Ismael Castañeda-Sánchez, Julieta Luna-Herrera, Gildardo Rivera-Sanchez

School of Integrative Biological & Chemical Sciences Faculty Publications

Mycetoma is currently considered as a neglected tropical disease. The incidence of mycetoma is unknown but most of the worldwide cases are present in the “mycetoma belt” including countries like Mexico, India, Senegal, and others. The treatment of mycetoma depends on the etiological agent responsible for the case. Treatment success reaches 60 to 90%; however, common treatment has been reported to be ineffective in some cases, due in part to resistance to the prescribed antibiotics. Therefore, it is necessary to develop new therapeutic options. In the past two decades, quinoxaline derivatives have shown relevance as antibacterial agents. Therefore, in this …


Sex Specific Differences In Ed Patient Mortality Predictors And Documentation Of End-Of-Life Goals Of Treatment., Jessica K. Eygnor Do, David B. Burmeister Do, Facep, Cpe, Jennifer Allen Md, Katie Best Rn, Marna R. Greenberg Do, Mph, Facep, Justin Stauffer Pa-C, David M. Richardson Md, Courtney Moore Md, Katelyn Mclain, Angelica Masullo Do, Timothy J. Friel Md Sep 2024

Sex Specific Differences In Ed Patient Mortality Predictors And Documentation Of End-Of-Life Goals Of Treatment., Jessica K. Eygnor Do, David B. Burmeister Do, Facep, Cpe, Jennifer Allen Md, Katie Best Rn, Marna R. Greenberg Do, Mph, Facep, Justin Stauffer Pa-C, David M. Richardson Md, Courtney Moore Md, Katelyn Mclain, Angelica Masullo Do, Timothy J. Friel Md

Department of Emergency Medicine

No abstract provided.


Advances In Deep Learning-Based Ultrasound Microscopy Of Microvasculature: Basic And Clinical Research, Ji-Bin Liu Sep 2024

Advances In Deep Learning-Based Ultrasound Microscopy Of Microvasculature: Basic And Clinical Research, Ji-Bin Liu

Department of Radiology Faculty Papers

No abstract provided.


Trace Out The Improvement Level And Awareness Of Polycyctic Ovary Syndrome (Pcos) Among General People And Educational Institute Of Developed And Developing Countries, Muhammad Rizwan, Maryam Mushtaq, Asif Bilal, Tabassum Nawaz, Kashif Riaz, Maria Hussain, Mirza Fahad Baig, Saira Ashfaq, Ayesha Mushtaq, Umair Riaz, Mariya Basharat Sep 2024

Trace Out The Improvement Level And Awareness Of Polycyctic Ovary Syndrome (Pcos) Among General People And Educational Institute Of Developed And Developing Countries, Muhammad Rizwan, Maryam Mushtaq, Asif Bilal, Tabassum Nawaz, Kashif Riaz, Maria Hussain, Mirza Fahad Baig, Saira Ashfaq, Ayesha Mushtaq, Umair Riaz, Mariya Basharat

Journal of Bioresource Management

One of the most prevalent hormonal problems which affect women is polycystic ovary syndrome (PCOS). It consists of several fundamentals, including reproductive, metabolic, and cardiovascular ones, and has effects on the patient's health throughout the duration of their life. Limited data is available on PCOS in developing countries like Pakistan. The aim of our study is to trace out the prevalence of PCOS in developed countries like America and China as well as developing countries like Pakistan. The study was done in the above mention developed and developing countries through the interviews of people by online questionnaire. This survey research …